Analysis of 2-[Fluorine-18]-Fluoro-2-deoxy-D-glucose Uptake Kinetics in PET Studies of Pulmonary Inflammation

Academic Radiology

Volumn 18, Issue 4, 2011, Pages 418-423

  Schroeder, Tobias ^a   Vidal Melo, Marcos F ^a   Venegas, Jose G ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Acute respiratory distress syndrome; Chronic obstructive pulmonary disease; Compartmental modeling; Cystic fibrosis; FDG; Lung inflammation; Positron emission tomography; Radionuclide imaging

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG UPTAKE; HUMAN; LUNG BURN; NON INVASIVE PROCEDURE; NONHUMAN; PNEUMONIA; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SHEEP;

COMPUTER SIMULATION; FLUORODEOXYGLUCOSE F18; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; KINETICS; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; PNEUMONIA; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS;

EID: 79952160098     PISSN: 10766332     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.acra.2010.11.019     Document Type: Article

References (39)

1. Jones H.A. Inflammation imaging. Proc Am Thorac Soc 2005, 2:513-514. 545-548.
2. Jones H.A., Donovan T., Goddard M.J., et al. Use of 18FDG-pet to discriminate between infection and rejection in lung transplant recipients. Transplantation 2004, 77:1462-1464.
3. Jones H.A., Marino P.S., Shakur B.H., et al. In vivo assessment of lung inflammatory cell activity in patients with COPD and asthma. Eur Respir J 2003, 21:567-573.
4. Costa E.L., Musch G., Winkler T., et al. Mild endotoxemia during mechanical ventilation produces spatially heterogeneous pulmonary neutrophilic inflammation in sheep. Anesthesiology 2010, 112:658-669.
5. de Prost N., Tucci M.R., Vidal Melo M.F. Assessment of lung inflammation with 18F-FDG PET during acute lung injury. Am J Roentgenol 2010, 195:292-300.
6. Schroeder T., Vidal Melo M.F., Musch G., et al. PET imaging of regional 18F-FDG uptake and lung function after cigarette smoke inhalation. J Nucl Med 2007, 48:413-419.
7. Chen D.L., Rosenbluth D.B., Mintun M.A., et al. FDG-PET imaging of pulmonary inflammation in healthy volunteers after airway instillation of endotoxin. J Appl Physiol 2006, 100:1602-1609.
8. Chen D.L., Ferkol T.W., Mintun M.A., et al. Quantifying pulmonary inflammation in cystic fibrosis with positron emission tomography. Am J Respir Crit Care Med 2006, 173:1363-1369.
9. Rodrigues R.S., Miller P.R., Bozza F.A., et al. FDG-PET in patients at risk for acute respiratory distress syndrome: a preliminary report. Intensive Care Med 2008, 34:2273-2278.
10. Jones H.A., Cadwallader K.A., White J.F., et al. Dissociation between respiratory burst activity and deoxyglucose uptake in human neutrophil granulocytes: implications for interpretation of (18)F-FDG PET images. J Nucl Med 2002, 43:652-657.
11. Jones H.A., Schofield J.B., Krausz T., et al. Pulmonary fibrosis correlates with duration of tissue neutrophil activation. Am J Respir Crit Care Med 1998, 158:620-628.
12. Gamelli R.L., Liu H., He L.K., et al. Augmentations of glucose uptake and glucose transporter-1 in macrophages following thermal injury and sepsis in mice. J Leukoc Biol 1996, 59:639-647.
13. Chakrabarti R., Jung C.Y., Lee T.P., et al. Changes in glucose transport and transporter isoforms during the activation of human peripheral blood lymphocytes by phytohemagglutinin. J Immunol 1994, 152:2660-2668.
14. Jones H.A., Clark R.J., Rhodes C.G., et al. In vivo measurement of neutrophil activity in experimental lung inflammation. Am J Respir Crit Care Med 1994, 149:1635-1639.
15. Hartwig W., Carter E.A., Jimenez R.E., et al. Neutrophil metabolic activity but not neutrophil sequestration reflects the development of pancreatitis-associated lung injury. Crit Care Med 2002, 30:2075-2082.
16. Chen D.L., Schuster D.P. Positron emission tomography with [18F]fluorodeoxyglucose to evaluate neutrophil kinetics during acute lung injury. Am J Physiol Lung Cell Mol Physiol 2004, 286:L834-L840.
17. Jones H.A., Sriskandan S., Peters A.M., et al. Dissociation of neutrophil emigration and metabolic activity in lobar pneumonia and bronchiectasis. Eur Respir J 1997, 10:795-803.
18. Holmes J.H., Sorkness R.L., Meibom S.K., et al. Noninvasive mapping of regional response to segmental allergen challenge using magnetic resonance imaging and [F-18]fluorodeoxyglucose positron emission tomography. Magn Reson Med 2005, 53:1243-1250.
19. Taylor I.K., Hill A.A., Hayes M., et al. Imaging allergen-invoked airway inflammation in atopic asthma with [18F]-fluorodeoxyglucose and positron emission tomography. Lancet 1996, 347:937-940.
20. Musch G., Venegas J.G., Bellani G., et al. Regional gas exchange and cellular metabolic activity in ventilator-induced lung injury. Anesthesiology 2007, 106:723-735.
21. Costa E.L., Vidal Melo M.F. Lung water: what you see (with computed tomography) and what you get (with a bedside device). Anesthesiology 2009, 111:933-935.
22. Miyauchi T., Wahl R.L. Regional 2-[18F]fluoro-2-deoxy-D-glucose uptake varies in normal lung. Eur J Nucl Med 1996, 23:517-523.
23. Mamede M., Higashi T., Kitaichi M., et al. 18F]FDG uptake and PCNA, Glut-1, and Hexokinase-II expressions in cancers and inflammatory lesions of the lung. Neoplasia 2005, 7:369-379.
24. Zasadny K.R., Wahl R.L. Standardized uptake values of normal tissues at PET with 2-[fluorine-18]-fluoro-2-deoxy-D-glucose: variations with body weight and a method for correction. Radiology 1993, 189:847-850.
25. Labiris N.R., Nahmias C., Freitag A.P., et al. Uptake of 18fluorodeoxyglucose in the cystic fibrosis lung: a measure of lung inflammation?. Eur Respir J 2003, 21:848-854.
26. Brudin L.H., Valind S.O., Rhodes C.G., et al. Fluorine-18 deoxyglucose uptake in sarcoidosis measured with positron emission tomography. Eur J Nucl Med 1994, 21:297-305.
27. Huang S.C. Anatomy of SUV. Standardized uptake value. Nucl Med Biol 2000, 27:643-646.
28. Hamberg L.M., Hunter G.J., Alpert N.M., et al. The dose uptake ratio as an index of glucose metabolism: useful parameter or oversimplification?. J Nucl Med 1994, 35:1308-1312.
29. Chen D.L., Mintun M.A., Schuster D.P. Comparison of methods to quantitate 18F-FDG uptake with PET during experimental acute lung injury. J Nucl Med 2004, 45:1583-1590.
30. Patlak C.S., Blasberg R.G., Fenstermacher J.D. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 1983, 3:1-7.
31. Schroeder T., Vidal Melo M.F., Musch G., et al. Image-derived input function for assessment of 18F-FDG uptake by the inflamed lung. J Nucl Med 2007, 48:1889-1896.
32. Gambhir S.S., Schwaiger M., Huang S.C., et al. Simple noninvasive quantification method for measuring myocardial glucose utilization in humans employing positron emission tomography and fluorine-18 deoxyglucose. J Nucl Med 1989, 30:359-366.
33. de Geus-Oei L.F., Visser E.P., Krabbe P.F., et al. Comparison of image-derived and arterial input functions for estimating the rate of glucose metabolism in therapy-monitoring 18F-FDG PET studies. J Nucl Med 2006, 47:945-949.
34. Ohtake T., Kosaka N., Watanabe T., et al. Noninvasive method to obtain input function for measuring tissue glucose utilization of thoracic and abdominal organs. J Nucl Med 1991, 32:1432-1438.
35. Reivich M., Kuhl D., Wolf A., et al. The [18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man. Circ Res 1979, 44:127-137.
36. Sokoloff L., Reivich M., Kennedy C., et al. The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 1977, 28:897-916.
37. Marquardt D. An algorithm for least-squares estimation of nonlinear parameters. SIAM J Appl Math 1963, 11:431-441.
38. Lammertsma A.A. Measurement of tumor response using [18F]-2-fluoro-2-deoxy-D-glucose and positron-emission tomography. J Clin Pharmacol 2001, (Suppl):104S-106S.
39. Schroeder T., Vidal Melo M.F., Musch G., et al. Modeling pulmonary kinetics of 2-deoxy-2-[(18)F]fluoro-d-glucose during acute lung injury. Acad Radiol 2008, 15:763-775.