PET imaging of regional18F-FDG uptake and lung function after cigarette smoke inhalation

Journal of Nuclear Medicine

Volumn 48, Issue 3, 2007, Pages 413-419

  Schroeder, Tobias ^a   Melo, Marcos F Vidal ^a   Musch, Guido ^a   Harris, R Scott ^a   Winkler, Tilo ^a   Venegas, Jose G ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

FDG; Inflammation; Positron emission tomography; Pulmonary gas exchange; Smoke inhalation injury

Indexed keywords

FLUORODEOXYGLUCOSE F 18; DIAGNOSTIC AGENT;

ANIMAL CELL; ARTICLE; ARTIFICIAL VENTILATION; CELL HETEROGENEITY; CIGARETTE SMOKING; CONTROLLED STUDY; CORRELATION COEFFICIENT; GAS ANALYSIS; LUNG FUNCTION; LUNG PERFUSION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; ANIMAL; EXPOSURE; FEMALE; LUNG; PHYSIOLOGY; SHEEP; SMOKE; TOBACCO;

ANIMALS; FEMALE; FLUORODEOXYGLUCOSE F18; INHALATION EXPOSURE; LUNG; POSITRON-EMISSION TOMOGRAPHY; SHEEP; SMOKE; TOBACCO;

EID: 34247195630     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. van der Vaart H, Postma DS, Timens W, ten Hacken NH. Acute effects of cigarette smoke on inflammation and oxidative stress: a review. Thorax. 2004;59:713-721.
2. MacNee W, Wiggs B, Belzberg AS, Hogg JC. The effect of cigarette smoking on neutrophil kinetics in human lungs. N Engl J Med. 1989;321:924-928.
3. Traber DL, Linares HA, Herndon DN, Prien T. The pathophysiology of inhalation injury: a review. Burns Incl Therm Inj. 1988;14:357-364.
4. Basadre JO, Sugi K, Traber DL, Traber LD, Niehaus GD, Herndon DN. The effect of leukocyte depletion on smoke inhalation injury in sheep. Surgery. 1988;104:208-215.
5. Ryan CM, Schoenfeld DA, Thorpe WP, Sheridan RL, Cassem EH, Tompkins RG. Objective estimates of the probability of death from burn injuries. N Engl J Med. 1998;338:362-366.
6. Devereux G. ABC of chronic obstructive pulmonary disease: definition, epidemiology, and risk factors. BMJ. 2006;332:1142-1144.
7. Chapman KR, Mannino DM, Soriano JB, et al. Epidemiology and costs of chronic obstructive pulmonary disease. Eur Respir J. 2006;27:188-207.
8. Gamble E, Qiu Y, Wang D, et al. Variability of bronchial inflammation in chronic obstructive pulmonary disease: implications for study design. Eur Respir J. 2006;27:293-299.
9. Willey-Courand DB, Harris RS, Galletti GG, Hales CA, Fischman A, Venegas JG. Alterations in regional ventilation, perfusion, and shunt after smoke inhalation measured by PET. J Appl Physiol. 2002;93:1115-1122.
10. Dhami R, Gilks B, Xie C, Zay K, Wright JL, Churg A. Acute cigarette smoke-induced connective tissue breakdown is mediated by neutrophils and prevented by alpha1-antitrypsin. Am J Respir Cell Mol Biol. 2000;22:244-252.
11. 18F]fluorodeoxyglucose to evaluate neutrophil kinetics during acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2004;286:L834-L840.
12. Jones HA, Schofield JB, Krausz T, Boobis AR, Haslett C. Pulmonary fibrosis correlates with duration of tissue neutrophil activation. Am J Respir Crit Care Med. 1998;158:620-628.
13. Chen DL, Rosenbluth DB, Mintun MA, Schuster DP. FDG-PET imaging of pulmonary inflammation in healthy volunteers after airway instillation of endotoxin. J Appl Physiol. 2006;100:1602-1609.
14. Vidal Melo MF, Layfield D, Harris RS, et al. Quantification of regional ventilation-perfusion ratios with PET. J Nucl Med. 2003;44:1982-1991.
15. Mijailovich SM, Treppo S, Venegas JG. Effects of lung motion and tracer kinetics corrections on PET imaging of pulmonary function. J Appl Physiol. 1997;82:1154-1162.
16. Harris RS, Willey-Courand DB, Head CA, Galletti GG, Call DM, Venegas JG. Regional VA, Q, and VA/Q during PLV: effects of nitroprusside and inhaled nitric oxide. J Appl Physiol. 2002;92:297-312.
17. Galletti GG, Venegas JG. Tracer kinetic model of regional pulmonary function using positron emission tomography. J Appl Physiol. 2002;93:1104-1114.
18. Patlak CS, Blasberg RG. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data: generalizations. J Cereb Blood Flow Metab. 1985;5:584-590.
19. Melo MF, Harris RS, Layfield JD, Venegas JG. Topographic basis of bimodal ventilation-perfusion distributions during bronchoconstriction in sheep. Am J Respir Crit Care Med. 2005;171:714-721.
20. Jones HA, Sriskandan S, Peters AM, et al. Dissociation of neutrophil emigration and metabolic activity in lobar pneumonia and bronchiectasis. Eur Respir J. 1997;10:795-803.
21. 18F-FDG uptake with PET during experimental acute lung injury. J Nucl Med. 2004;45:1583-1590.