-
1
-
-
54249104477
-
Nitric oxide in inflammation and pain associated with osteoarthritis
-
Abramson S.B.: Nitric oxide in inflammation and pain associated with osteoarthritis. Arthritis Res. Ther., 2008, 10 (supl. 2), S2.
-
(2008)
Arthritis Res. Ther.
, vol.10
, Issue.SUPL. 2
-
-
Abramson, S.B.1
-
2
-
-
79952181630
-
Efficacy, safety and effects on BP of Naproxcinod 750 Mg bid compared with Placebo and Naproxen 500 Mg bid in patients with osteoarthritis of the hip
-
Epub ahead of print
-
Baerwald C., Verdecchia P., Duquesroix B. i wsp.: Efficacy, safety and effects on BP of Naproxcinod 750 Mg bid compared with Placebo and Naproxen 500 Mg bid in patients with osteoarthritis of the hip. Arthritis Rheum., 2010, 18 [Epub ahead of print].
-
(2010)
Arthritis Rheum.
, pp. 18
-
-
Baerwald, C.1
Verdecchia, P.2
Duquesroix, B.3
-
3
-
-
51449109599
-
Physiological mediators in nonsteroidal anti-inflammatory drugs (NSAIDs)-induced impairment of gastric mucosal defense and adaptation. Focus on nitric oxide and lipoxins
-
Brzozowski T., Konturek P.C., Pajdo R. i wsp.: Physiological mediators in nonsteroidal anti-inflammatory drugs (NSAIDs)-induced impairment of gastric mucosal defense and adaptation. Focus on nitric oxide and lipoxins. J. Physiol. Pharmacol., 2008, 59, supl. 2, 89-102.
-
(2008)
J. Physiol. Pharmacol.
, vol.59
, Issue.SUPL. 2
, pp. 89-102
-
-
Brzozowski, T.1
Konturek, P.C.2
Pajdo, R.3
-
4
-
-
10044244823
-
Nitric oxide (NO)-releasing naproxen (HCT-3012 [(S)-6-methoxy-alpha- methyl-2-naphthaleneacetic acid 4-(nitrooxy)butyl ester]) interactions with aspirin ingastric mucosa of arthritic rats reveal a role for aspirin triggered lipoxin, prostaglandins, and NO in gastric protection
-
Fiorucci S., Di Lorenzo A., Renga B. i wsp.: Nitric oxide (NO)-releasing naproxen (HCT-3012 [(S)-6-methoxy-alpha-methyl-2-naphthaleneacetic acid 4-(nitrooxy)butyl ester]) interactions with aspirin ingastric mucosa of arthritic rats reveal a role for aspirin triggered lipoxin, prostaglandins, and NO in gastric protection. J. Pharmacol. Exp Ther., 2004, 311, 1264-1271.
-
(2004)
J. Pharmacol. Exp Ther.
, vol.311
, pp. 1264-1271
-
-
Fiorucci, S.1
Di Lorenzo, A.2
Renga, B.3
-
5
-
-
33847619273
-
Cyclo-oxygenase (COX) inhibiting nitric oxide donating (CINODs) drugs: A review of their current status
-
Fiorucci S., Distrutti E.: Cyclo-oxygenase (COX) inhibiting nitric oxide donating (CINODs) drugs: a review of their current status. Curr. Top. Med. Chem., 2007, 7, 277-282.
-
(2007)
Curr. Top. Med. Chem.
, vol.7
, pp. 277-282
-
-
Fiorucci, S.1
Distrutti, E.2
-
6
-
-
67649133149
-
Naproxcinod, a new cyclooxygenase-inhibiting nitric oxide donátor (CINOD)
-
Geusens P.: Naproxcinod, a new cyclooxygenase-inhibiting nitric oxide donátor (CINOD). Expert Opin. Biol. Ther., 2009, 9, 649-657.
-
(2009)
Expert Opin. Biol. Ther.
, vol.9
, pp. 649-657
-
-
Geusens, P.1
-
7
-
-
0242329755
-
Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator proof of concept study in humans
-
Hawkey C.J., Jones J.I., Atherton CT. i wsp.: Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator proof of concept study in humans. Gut 2003, 52, 1537-1542.
-
(2003)
Gut
, vol.52
, pp. 1537-1542
-
-
Jones, J.I.1
Atherton, C.T.2
-
8
-
-
33751015422
-
Analgesic efficacy of the cyclooxygenase-inhibiting nitric oxide donor AZD3582 in postoperative dental pain: Comparison with naproxen and rofecoxib in two randomized, double-blind, placebo-controlled studies
-
Hill M.C., Sindet-Pederson S., Seymour R.A. i wsp.: Analgesic efficacy of the cyclooxygenase-inhibiting nitric oxide donor AZD3582 in postoperative dental pain: Comparison with naproxen and rofecoxib in two randomized, double-blind, placebo-controlled studies. Clin. Ther., 2006, 28, 1279-1295.
-
(2006)
Clin. Ther.
, vol.28
, pp. 1279-1295
-
-
Hill, M.C.1
Sindet-Pederson, S.2
Seymour, R.A.3
-
9
-
-
67149147431
-
TJ. Efficacy, safety, and tolerability of the cyclooxygenase-inhibiting nitric oxide donátor naproxcinod in treating osteoarthritis of the hip or knee
-
Karlsson J., Pivodic A., Aguirre D. i wsp.: TJ. Efficacy, safety, and tolerability of the cyclooxygenase-inhibiting nitric oxide donátor naproxcinod in treating osteoarthritis of the hip or knee. J. Rheumatol., 2009, 36(6), 1290-1297.
-
(2009)
J. Rheumatol.
, vol.36
, Issue.6
, pp. 1290-1297
-
-
Karlsson, J.1
Pivodic, A.2
Aguirre, D.3
-
10
-
-
14144252695
-
A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis
-
Lohmander L.S., McKeith D., Svensson O. i wsp.: A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis. Ann. Rheum. Dis., 2005, 64(3), 449-456.
-
(2005)
Ann. Rheum. Dis.
, vol.64
, Issue.3
, pp. 449-456
-
-
Lohmander, L.S.1
McKeith, D.2
Svensson, O.3
-
11
-
-
54249123143
-
Nitric oxide and cardiovascular effects: New insights in the role of nitric oxide for the management of osteoarthritis
-
Mackenzie I.S., Rutherford D., MacDonald T.M.: Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis. Arthritis Res. Ther., 2008, 10, supl. 2, S3.
-
(2008)
Arthritis Res. Ther.
, vol.10
, Issue.SUPL. 2
-
-
Mackenzie, I.S.1
Rutherford, D.2
MacDonald, T.M.3
-
12
-
-
70350127334
-
Lipoxins: Resolutionary road
-
Maderna P., Godson C.: Lipoxins: resolutionary road. Br. J. Pharmacol., 2009, 158 (4), 947-959.
-
(2009)
Br. J. Pharmacol.
, vol.158
, Issue.4
, pp. 947-959
-
-
Maderna, P.1
Godson, C.2
-
13
-
-
33646904034
-
COX-inhibiting nitric oxide donors (CINODs): Potential benefits on cardiovascular and renal function
-
Muscará M.N., Wallace J.L.: COX-inhibiting nitric oxide donors (CINODs): potential benefits on cardiovascular and renal function. Cardiovasc. Hematol. Agents Med. Chem., 2006, 4 (2), 155-164.
-
(2006)
Cardiovasc. Hematol. Agents Med. Chem.
, vol.4
, Issue.2
, pp. 155-164
-
-
Muscará, M.N.1
Wallace, J.L.2
-
14
-
-
77954697249
-
Przeciwzapalne prowygaszeniowe pochodne wielonienasyconych kwasów tluszczowych omega 3 i omega 6
-
Nowak J.Z.: Przeciwzapalne "prowygaszeniowe" pochodne wielonienasyconych kwasów tluszczowych omega 3 i omega 6. Postȩpy Hig. Med. Dośw., 2010, 64, 115-132.
-
(2010)
Postȩpy Hig. Med. Dośw.
, vol.64
, pp. 115-132
-
-
Nowak, J.Z.1
-
15
-
-
2342541859
-
Mechanisms of nonsteroidal anti-inflammatory drug-induced gastrointestinal injury and repair: A window of opportunity for cyclooxygenase-inhibiting nitric oxide donors
-
Perini R., Fiorucci S., Wallace J.L.: Mechanisms of nonsteroidal anti-inflammatory drug-induced gastrointestinal injury and repair: a window of opportunity for cyclooxygenase-inhibiting nitric oxide donors. Can. J. Gastroenterol., 2004, 18 (4), 229-236.
-
(2004)
Can. J. Gastroenterol.
, vol.18
, Issue.4
, pp. 229-236
-
-
Perini, R.1
Fiorucci, S.2
Wallace, J.L.3
-
16
-
-
77952547893
-
Efficacy and safety of naproxcinod in the treatment of patients with osteoarthritis of the knee: A 13-week prospective, randomized, mutticenter study
-
Schnitzer T.J., Kivitz A., Frayssinet H. i wsp.: Efficacy and safety of naproxcinod in the treatment of patients with osteoarthritis of the knee: a 13-week prospective, randomized, mutticenter study. Osteoarthritis Cartilage, 2010, 18, 629-639.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, pp. 629-639
-
-
Schnitzer, T.J.1
Kivitz, A.2
Frayssinet, H.3
-
17
-
-
29144446030
-
Comparison of the COXinhibiting nitric oxide donator AZD3582 and rofecoxib in treating the signs and symptoms of Osteoarthritis of the knee
-
Schnitzer T.J., Kivitz A.J., Lipetz R.S. i wsp.: Comparison of the COXinhibiting nitric oxide donator AZD3582 and rofecoxib in treating the signs and symptoms of Osteoarthritis of the knee. Arthritis Rheum., 2005, 53 (6), 827-837.
-
(2005)
Arthritis Rheum.
, vol.53
, Issue.6
, pp. 827-837
-
-
Schnitzer, T.J.1
Kivitz, A.J.2
Lipetz, R.S.3
-
18
-
-
34748841476
-
Hydrogen sulfide-releasing anti-inflammatory drugs
-
Wallace J.L.: Hydrogen sulfide-releasing anti-inflammatory drugs. Trends Pharmacol. Sci., 2007, 28 (10), 501-505.
-
(2007)
Trends Pharmacol. Sci.
, vol.28
, Issue.10
, pp. 501-505
-
-
Wallace, J.L.1
-
19
-
-
77950792008
-
Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract
-
Wallace J.L.: Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract. Antioxidants & Redox Signaling, 2010, 12, 1125-1133.
-
(2010)
Antioxidants & Redox Signaling
, vol.12
, pp. 1125-1133
-
-
Wallace, J.L.1
-
20
-
-
33846184714
-
Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide-releasing diclofenac derivative in the rat
-
Wallace J.L., Caliendo G., Santagada V. i wsp.: Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide-releasing diclofenac derivative in the rat. Gastroenterology, 2007, 132 (1), 261-271.
-
(2007)
Gastroenterology
, vol.132
, Issue.1
, pp. 261-271
-
-
Wallace, J.L.1
Caliendo, G.2
Santagada, V.3
-
21
-
-
77949379109
-
Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346)
-
Wallace J.L., Caliendo G., Santagada V. i wsp.: Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346). Br. J. Pharmacol., 2010, 159, 1236-1246.
-
(2010)
Br. J. Pharmacol.
, vol.159
, pp. 1236-1246
-
-
Wallace, J.L.1
Caliendo, G.2
Santagada, V.3
-
22
-
-
0033868029
-
Nitric oxide in mucosal defense: A little goes a long way
-
Wallace J.L., Miller M.J.S.: Nitric oxide in mucosal defense: a little goes a long way. Gastroenterology, 2000, 119, 512-20.
-
(2000)
Gastroenterology
, vol.119
, pp. 512-520
-
-
Wallace, J.L.1
Miller, M.J.S.2
-
23
-
-
34347387762
-
The effects of AZD3582 [4-(nitroxy)butyl-(2S)-2-(6-methoxy-2-naphthyl) propanoate], and naproxen on key pathogenic steps in NSAID-enteropathy in the rat
-
Walley M., Sigthorsson G., Hotz-Behofsits C. i wsp.: The effects of AZD3582 [4-(nitroxy)butyl-(2S)-2-(6-methoxy-2-naphthyl) propanoate], and naproxen on key pathogenic steps in NSAID-enteropathy in the rat. Inflammopharmacology, 2007, 15 (3), 119-123.
-
(2007)
Inflammopharmacology
, vol.15
, Issue.3
, pp. 119-123
-
-
Walley, M.1
Sigthorsson, G.2
Hotz-Behofsits, C.3
-
24
-
-
69449105980
-
Effects of the cyclooxygenase inhibiting nitric oxide donator naproxcinod versus naproxen on systemic blood pressure in patients with osteoarthritis
-
White W.B., Schnitzer T.J., Fleming R. i wsp.: Effects of the cyclooxygenase inhibiting nitric oxide donator naproxcinod versus naproxen on systemic blood pressure in patients with osteoarthritis. Am. J. Cardiol., 2009, 104 (6), 840-845.
-
(2009)
Am. J. Cardiol.
, vol.104
, Issue.6
, pp. 840-845
-
-
White, W.B.1
Schnitzer, T.J.2
Fleming, R.3
-
25
-
-
0842327466
-
Nitric oxide and the gut injury induced by non-steroidal antiinflammatory drugs
-
Whittle B.J.: Nitric oxide and the gut injury induced by non-steroidal antiinflammatory drugs. Inflammopharmacology, 2003, 11 (4), 415-422.
-
(2003)
Inflammopharmacology
, vol.11
, Issue.4
, pp. 415-422
-
-
Whittle, B.J.1
-
26
-
-
33644588856
-
Dose-effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects
-
Wilder-Smith C.H., Jonzon B., Fornstedt-Wallin B. i wsp.: Dose-effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects. Scand. J. Gastroenterol., 2006, 41 (3), 264-273.
-
(2006)
Scand. J. Gastroenterol.
, vol.41
, Issue.3
, pp. 264-273
-
-
Wilder-Smith, C.H.1
Jonzon, B.2
Fornstedt-Wallin, B.3
|