메뉴 건너뛰기




Volumn 108, Issue 4, 2011, Pages 1693-1698

Augmented glucose-induced insulin release in mice lacking Go2, but not Go1or Gi proteins

Author keywords

Exocytosis; G protein coupled receptor; Islet activating protein; Signal transduction; Somatostatin

Indexed keywords

GLUCOSE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PERTUSSIS TOXIN;

EID: 79952126080     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018903108     Document Type: Article
Times cited : (23)

References (50)
  • 1
    • 0030474003 scopus 로고    scopus 로고
    • Mechanisms of inhibition of insulin release
    • Sharp GW (1996) Mechanisms of inhibition of insulin release. Am J Physiol 271:C1781-C1799.
    • (1996) Am J Physiol , vol.271
    • Sharp, G.W.1
  • 2
    • 0033556082 scopus 로고    scopus 로고
    • Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion
    • Lang J (1999) Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion. Eur J Biochem 259:3-17.
    • (1999) Eur J Biochem , vol.259 , pp. 3-17
    • Lang, J.1
  • 4
    • 0029797647 scopus 로고    scopus 로고
    • Regulation of insulin secretion by phospholipase C
    • Zawalich WS, Zawalich KC (1996) Regulation of insulin secretion by phospholipase C. Am J Physiol 271:E409-E416.
    • (1996) Am J Physiol , vol.271
    • Zawalich, W.S.1    Zawalich, K.C.2
  • 5
    • 0014348106 scopus 로고
    • Metabolic effects of pertussis sensitization in mice and rats
    • Gulbenkian A, Schobert L, Nixon, Tabachnick II (1968) Metabolic effects of pertussis sensitization in mice and rats. Endocrinology 83:885-892.
    • (1968) Endocrinology , vol.83 , pp. 885-892
    • Gulbenkian, A.1    Schobert, L.2    Nixon3    Tabachnick, I.I.4
  • 6
    • 0017912701 scopus 로고
    • Islets-activating protein (IAP) in Bordetella pertussis that potentiates insulin secretory responses of rats. Purification and characterization
    • Yajima M, et al. (1978) Islets-activating protein (IAP) in Bordetella pertussis that potentiates insulin secretory responses of rats. Purification and characterization. J Biochem 83:295-303. (Pubitemid 8273508)
    • (1978) Journal of Biochemistry , vol.38 , Issue.1 , pp. 295-303
    • Yajima, M.1    Hosoda, K.2    Kanbayashi, Y.3
  • 7
    • 0018379821 scopus 로고
    • Islet-activating protein. Enhanced insulin secretion and cyclic AMP accumulation in pancreatic islets due to activation of native calcium ionophores
    • Katada T, Ui M (1979) Islet-activating protein. Enhanced insulin secretion and cyclic AMP accumulation in pancreatic islets due to activation of native calcium ionophores. J Biol Chem 254:469-479. (Pubitemid 9142968)
    • (1979) Journal of Biological Chemistry , vol.254 , Issue.2 , pp. 469-479
    • Katada, T.1    Ui, M.2
  • 8
    • 0014040284 scopus 로고
    • A receptor mechanism for the inhibition of insulin release by epinephrine in man
    • Porte D, Jr. (1967) A receptor mechanism for the inhibition of insulin release by epinephrine in man. J Clin Invest 46:86-94.
    • (1967) J Clin Invest , vol.46 , pp. 86-94
    • Porte Jr., D.1
  • 9
    • 0023270607 scopus 로고
    • Inhibition of insulin release by galanin and gastrin-releasing peptide in the anaesthetized rat
    • Schnuerer EM, McDonald TJ, Dupre J (1987) Inhibition of insulin release by galanin and gastrin-releasing peptide in the anaesthetized rat. Regul Pept 18:307-320. (Pubitemid 17138598)
    • (1987) Regulatory Peptides , vol.18 , Issue.5-6 , pp. 307-320
    • Schnuerer, E.M.1    McDonald, T.J.2    Dupre, J.3
  • 10
    • 0037372044 scopus 로고    scopus 로고
    • Dose-dependent inhibition by ghrelin of insulin secretion in the mouse
    • DOI 10.1210/en.2002-220819
    • Reimer MK, Pacini G, Ahrén B (2003) Dose-dependent inhibition by ghrelin of insulin secretion in the mouse. Endocrinology 144:916-921. (Pubitemid 36262858)
    • (2003) Endocrinology , vol.144 , Issue.3 , pp. 916-921
    • Reimer, M.K.1    Pacini, G.2    Ahren, B.3
  • 11
    • 0020490738 scopus 로고
    • ADP ribosylation of the specific membrane protein of C6 cells by islet-activating protein associated with modification of adenylate cyclase activity
    • Katada T, Ui M (1982) ADP ribosylation of the specific membrane protein of C6 cells by islet-activating protein associated with modification of adenylate cyclase activity. J Biol Chem 257:7210-7216.
    • (1982) J Biol Chem , vol.257 , pp. 7210-7216
    • Katada, T.1    Ui, M.2
  • 12
    • 60149091355 scopus 로고    scopus 로고
    • Molecular mechanisms of Go signaling
    • Jiang M, Bajpayee NS (2009) Molecular mechanisms of Go signaling. Neurosignals 17:23-41.
    • (2009) Neurosignals , vol.17 , pp. 23-41
    • Jiang, M.1    Bajpayee, N.S.2
  • 13
    • 11744265275 scopus 로고    scopus 로고
    • Multiple neurological abnormalities in mice deficient in the G protein Go
    • Jiang M, et al. (1998) Multiple neurological abnormalities in mice deficient in the G protein Go. Proc Natl Acad Sci USA 95:3269-3274.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3269-3274
    • Jiang, M.1
  • 15
    • 0029061801 scopus 로고
    • Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice
    • Rudolph U, et al. (1995) Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice. Nat Genet 10:143-150.
    • (1995) Nat Genet , vol.10 , pp. 143-150
    • Rudolph, U.1
  • 16
    • 0021683990 scopus 로고
    • Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase
    • Neer EJ, Lok JM, Wolf LG (1984) Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase. J Biol Chem 259:14222-14229. (Pubitemid 15224000)
    • (1984) Journal of Biological Chemistry , vol.259 , Issue.22 , pp. 14222-14229
    • Neer, E.J.1    Lok, J.M.2    Wolf, L.G.3
  • 17
    • 0021748090 scopus 로고
    • Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain
    • Sternweis PC, Robishaw JD (1984) Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain. J Biol Chem 259:13806-13813. (Pubitemid 15224957)
    • (1984) Journal of Biological Chemistry , vol.259 , Issue.22 , pp. 13806-13813
    • Sternweis, P.C.1    Robishaw, J.D.2
  • 18
    • 0023259760 scopus 로고
    • Immunological localization of the GTP-binding protein G(o) in different tissues of vertebrates and invertebrates
    • Homburger V, et al. (1987) Immunological localization of the GTP-binding protein Go in different tissues of vertebrates and invertebrates. Mol Pharmacol 31:313-319. (Pubitemid 17069797)
    • (1987) Molecular Pharmacology , vol.31 , Issue.4 , pp. 313-319
    • Homburger, V.1    Brabet, P.2    Audigier, Y.3
  • 19
  • 20
    • 36148996843 scopus 로고    scopus 로고
    • G-protein-coupled receptors and islet function-Implications for treatment of type 2 diabetes
    • DOI 10.1016/j.pharmthera.2007.08.002, PII S0163725807001593
    • Winzell MS, Ahrén B (2007) G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes. Pharmacol Ther 116:437-448. (Pubitemid 350116941)
    • (2007) Pharmacology and Therapeutics , vol.116 , Issue.3 , pp. 437-448
    • Winzell, M.S.1    Ahren, B.2
  • 21
    • 0019783304 scopus 로고
    • Islet-activating protein. A modifier of receptor-mediated regulation of rat islet adenylate cyclase
    • Katada T, Ui M (1981) Islet-activating protein. A modifier of receptor-mediated regulation of rat islet adenylate cyclase. J Biol Chem 256:8310-8317. (Pubitemid 12254783)
    • (1981) Journal of Biological Chemistry , vol.256 , Issue.16 , pp. 8310-8317
    • Katada, T.1    Ui, M.2
  • 23
    • 0025193752 scopus 로고
    • 2+-induced insulin secretion in permeabilized HIT-T15 cells
    • Ullrich S, Prentki M, Wollheim CB (1990) Somatostatin inhibition of Ca2(+)-induced insulin secretion in permeabilized HIT-T15 cells. Biochem J 270:273-276. (Pubitemid 20275609)
    • (1990) Biochemical Journal , vol.270 , Issue.1 , pp. 273-276
    • Ullrich, S.1    Prentki, M.2    Wollheim, C.B.3
  • 24
    • 0023875709 scopus 로고
    • GTP-dependent inhibition of insulin secretion by epinephrine in permeabilized RINm5F cells. Lack of correlation between insulin secretion and cyclic AMP levels
    • Ullrich S, Wollheim CB (1988) GTP-dependent inhibition of insulin secretion by epinephrine in permeabilized RINm5F cells. Lack of correlation between insulin secretion and cyclic AMP levels. J Biol Chem 263:8615-8620.
    • (1988) J Biol Chem , vol.263 , pp. 8615-8620
    • Ullrich, S.1    Wollheim, C.B.2
  • 25
    • 0024542459 scopus 로고
    • Galanin inhibits insulin secretion by direct interference with exocytosis
    • DOI 10.1016/0014-5793(89)81379-1
    • Ullrich S, Wollheim CB (1989) Galanin inhibits insulin secretion by direct interference with exocytosis. FEBS Lett 247:401-404. (Pubitemid 19129286)
    • (1989) FEBS Letters , vol.247 , Issue.2 , pp. 401-404
    • Ullrich, S.1    Wollheim, C.B.2
  • 26
    • 77957551212 scopus 로고    scopus 로고
    • Gαo represses insulin secretion by reducing vesicular docking in pancreatic beta-cells
    • Zhao A, et al. (2010) Gαo represses insulin secretion by reducing vesicular docking in pancreatic beta-cells. Diabetes 59:2522-2529.
    • (2010) Diabetes , vol.59 , pp. 2522-2529
    • Zhao, A.1
  • 27
    • 0347224273 scopus 로고    scopus 로고
    • ialpha1 Constraints on Adenylyl Cyclase in the Hippocampus Enhances LTP and Impairs Memory Formation
    • DOI 10.1016/S0896-6273(03)00813-4
    • Pineda VV, et al. (2004) Removal of G(ialpha1) constraints on adenylyl cyclase in the hippocampus enhances LTP and impairs memory formation. Neuron 41:153-163. (Pubitemid 38068441)
    • (2004) Neuron , vol.41 , Issue.1 , pp. 153-163
    • Pineda, V.V.1    Athos, J.I.2    Wang, H.3    Celver, J.4    Ippolito, D.5    Boulay, G.6    Birnbaumer, L.7    Storm, D.R.8
  • 28
    • 84880505498 scopus 로고
    • Islet activating protein (IAP) derived from the culture supernatant fluid of Bordetella pertussis: Effect on spontaneous diabetic rats
    • DOI 10.1007/BF01223023
    • Toyota T, et al. (1978) Islet activating protein (IAP) derived from the culture supernatant fluid of Bordetella pertussis: Effect on spontaneous diabetic rats. Diabetologia 14:319-323. (Pubitemid 8321893)
    • (1978) Diabetologia , vol.14 , Issue.5 , pp. 319-323
    • Toyota, T.1    Kakizaki, M.2    Kimura, K.3
  • 30
    • 0025186375 scopus 로고
    • At least three alternatively spliced mRNAs encoding two alpha subunits of the Go GTP-binding protein can be expressed in a single tissue
    • Bertrand P, Sanford J, Rudolph U, Codina J, Birnbaumer L (1990) At least three alternatively spliced mRNAs encoding two alpha subunits of the Go GTP-binding protein can be expressed in a single tissue. J Biol Chem 265:18576-18580.
    • (1990) J Biol Chem , vol.265 , pp. 18576-18580
    • Bertrand, P.1    Sanford, J.2    Rudolph, U.3    Codina, J.4    Birnbaumer, L.5
  • 31
    • 0025302838 scopus 로고
    • Molecular cloning of a novel splice variant of the alpha subunit of the mammalian Go protein
    • Hsu WH, et al. (1990) Molecular cloning of a novel splice variant of the alpha subunit of the mammalian Go protein. J Biol Chem 265:11220-11226.
    • (1990) J Biol Chem , vol.265 , pp. 11220-11226
    • Hsu, W.H.1
  • 32
    • 0025134833 scopus 로고
    • Alternative splicing produces transcripts encoding two forms of the alpha subunit of GTP-binding protein Go
    • Strathmann M, Wilkie TM, Simon MI (1990) Alternative splicing produces transcripts encoding two forms of the alpha subunit of GTP-binding protein Go. Proc Natl Acad Sci USA 87:6477-6481.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6477-6481
    • Strathmann, M.1    Wilkie, T.M.2    Simon, M.I.3
  • 33
    • 0027245830 scopus 로고
    • Substitution of three amino acids switches receptor specificity of G(q)alpha to that of G(i)alpha
    • DOI 10.1038/363274a0
    • Conklin BR, Farfel Z, Lustig KD, Julius D, Bourne HR (1993) Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha. Nature 363:274-276. (Pubitemid 23158533)
    • (1993) Nature , vol.363 , Issue.6426 , pp. 274-276
    • Conklin, B.R.1    Farfel, Z.2    Lustig, K.D.3    Julius, D.4    Bourne, H.R.5
  • 34
    • 0023716027 scopus 로고
    • Site of G protein binding to rhodopsin mapped with synthetic peptides from the alpha subunit
    • Hamm HE, et al. (1988) Site of G protein binding to rhodopsin mapped with synthetic peptides from the alpha subunit. Science 241:832-835.
    • (1988) Science , vol.241 , pp. 832-835
    • Hamm, H.E.1
  • 35
    • 0025880464 scopus 로고
    • Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents
    • Kleuss C, et al. (1991) Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents. Nature 353:43-48. (Pubitemid 21912448)
    • (1991) Nature , vol.353 , Issue.6339 , pp. 43-48
    • Kleuss, C.1    Hescheler, J.2    Ewel, C.3    Rosenthal, W.4    Schultz, G.5    Wittig, B.6
  • 36
    • 0026429190 scopus 로고
    • Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells
    • Hasty P, Ramírez-Solis R, Krumlauf R, Bradley A (1991) Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells. Nature 350:243-246. (Pubitemid 21912210)
    • (1991) Nature , vol.350 , Issue.6315 , pp. 243-246
    • Hasty, P.1    Ramirez-Solis, R.2    Krumlauf, R.3    Bradley, A.4
  • 38
    • 0030025047 scopus 로고    scopus 로고
    • Insulin action impaired by deficiency of the G-protein subunit G(ialpha2)
    • DOI 10.1038/379840a0
    • Moxham CM, Malbon CC (1996) Insulin action impaired by deficiency of the G-protein subunit G ialpha2. Nature 379:840-844. (Pubitemid 26067728)
    • (1996) Nature , vol.379 , Issue.6568 , pp. 840-844
    • Moxham, C.M.1    Malbon, C.C.2
  • 40
    • 41949090763 scopus 로고    scopus 로고
    • Galphaz negatively regulates insulin secretion and glucose clearance
    • Kimple ME, et al. (2008) Galphaz negatively regulates insulin secretion and glucose clearance. J Biol Chem 283:4560-4567.
    • (2008) J Biol Chem , vol.283 , pp. 4560-4567
    • Kimple, M.E.1
  • 42
    • 70350543344 scopus 로고    scopus 로고
    • Genetic disruption of G proteins, G(i2)alpha or G(o)alpha, does not abolish inotropic and chronotropic effects of stimulating muscarinic cholinoceptors in atrium
    • Boknik P, et al. (2009) Genetic disruption of G proteins, G(i2)alpha or G(o)alpha, does not abolish inotropic and chronotropic effects of stimulating muscarinic cholinoceptors in atrium. Br J Pharmacol 158:1557-1564.
    • (2009) Br J Pharmacol , vol.158 , pp. 1557-1564
    • Boknik, P.1
  • 44
    • 77957828604 scopus 로고    scopus 로고
    • Coordinated control of sensitivity by two splice variants of Gα(o) in retinal on bipolar cells
    • Okawa H, Pahlberg J, Rieke F, Birnbaumer L, Sampath AP (2010) Coordinated control of sensitivity by two splice variants of Gα(o) in retinal ON bipolar cells. J Gen Physiol 136:443-454.
    • (2010) J Gen Physiol , vol.136 , pp. 443-454
    • Okawa, H.1    Pahlberg, J.2    Rieke, F.3    Birnbaumer, L.4    Sampath, A.P.5
  • 45
    • 41949124929 scopus 로고    scopus 로고
    • Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel
    • Zhao Y, Fang Q, Straub SG, Sharp GW (2008) Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel. J Biol Chem 283:5306-5316.
    • (2008) J Biol Chem , vol.283 , pp. 5306-5316
    • Zhao, Y.1    Fang, Q.2    Straub, S.G.3    Sharp, G.W.4
  • 46
    • 0030757059 scopus 로고    scopus 로고
    • Receptors couple to L-type calcium channels via distinct G(o) proteins in rat neuroendocrine cell lines
    • DOI 10.1111/j.1469-7793.1997.321bk.x
    • Degtiar VE, Harhammer R, Nürnberg B (1997) Receptors couple to L-type calcium channels via distinct Go proteins in rat neuroendocrine cell lines. J Physiol 502:321-333. (Pubitemid 27352714)
    • (1997) Journal of Physiology , vol.502 , Issue.2 , pp. 321-333
    • Degtiar, V.E.1    Harhammer, R.2    Nurnberg, B.3
  • 47
    • 0023650902 scopus 로고
    • Presence of three pertussis toxin substrates and Go alpha immunoreactivity in both plasma and granule membranes of chromaffin cells
    • Toutant M, Aunis D, Bockaert J, Homburger V, Rouot B (1987) Presence of three pertussis toxin substrates and Go alpha immunoreactivity in both plasma and granule membranes of chromaffin cells. FEBS Lett 215:339-344.
    • (1987) FEBS Lett , vol.215 , pp. 339-344
    • Toutant, M.1    Aunis, D.2    Bockaert, J.3    Homburger, V.4    Rouot, B.5
  • 48
    • 0026635015 scopus 로고
    • Regulatory role of the GTP-binding protein, G(o), in the mechanism of exocytosis in adrenal chromaffin cells
    • Ohara-Imaizumi M, et al. (1992) Regulatory role of the GTP-binding protein, G(o), in the mechanism of exocytosis in adrenal chromaffin cells. J Neurochem 58:2275-2284.
    • (1992) J Neurochem , vol.58 , pp. 2275-2284
    • Ohara-Imaizumi, M.1
  • 49
    • 0029092604 scopus 로고
    • Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits
    • Lang J, et al. (1995) Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits. EMBO J 14:3635-3644.
    • (1995) EMBO J , vol.14 , pp. 3635-3644
    • Lang, J.1
  • 50
    • 77956750983 scopus 로고    scopus 로고
    • Noradrenaline inhibits exocytosis via the G protein βγ subunit and refilling of the readily releasable granule pool via the α(i1/2) subunit
    • Zhao Y, Fang Q, Straub SG, Lindau M, Sharp GW (2010) Noradrenaline inhibits exocytosis via the G protein βγ subunit and refilling of the readily releasable granule pool via the α(i1/2) subunit. J Physiol 588:3485-3498.
    • (2010) J Physiol , vol.588 , pp. 3485-3498
    • Zhao, Y.1    Fang, Q.2    Straub, S.G.3    Lindau, M.4    Sharp, G.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.