Gαo represses insulin secretion by reducing vesicular docking in pancreatic β-cells

Diabetes

Volumn 59, Issue 10, 2010, Pages 2522-2529

  Zhao, Aizhen ^a   Ohara Imaizumi, Mica ^b   Brissova, Marcella ^a,c,d   Benninger, Richard K P ^a   Xu, Yanwen ^a   Hao, Yuhan ^a   Abramowitz, Joel ^e   Boulay, Guylain ^f   Powers, Alvin C ^a,c,d   Piston, David ^a   Jiang, Meisheng ^g   Nagamatsu, Shinya ^b   Birnbaumer, Lutz ^e   Gu, Oqiang ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^f UNIVERSITÉ DE SHERBROOKE   (Canada)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GUANINE NUCLEOTIDE BINDING PROTEIN; HORMONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASSAY; CELL COUNT; CELL ISOLATION; CELL MEMBRANE; CELL VACUOLE; ELECTRON MICROSCOPE; GENE DELETION; IMMUNOASSAY; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; MOLECULAR DOCKING; MOUSE; MUTANT; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

ANIMALS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS; HOMEODOMAIN PROTEINS; HOMEOSTASIS; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 77957551212     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-1719     Document Type: Article

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