In Vitro interactions of extracellular histones with LDL suggest a potential pro-atherogenic role

PLoS ONE

Volumn 5, Issue 3, 2010, Pages

  Pemberton, Alan D ^a   Brown, Jeremy K ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN; HIGH DENSITY LIPOPROTEIN; HISTONE; LOW DENSITY LIPOPROTEIN; SEPHAROSE;

ANIMAL; ARTICLE; ATHEROSCLEROSIS; CELL NUCLEUS; CHEMISTRY; FOAM CELL; IN VITRO STUDY; INFLAMMATION; MACROPHAGE; METABOLISM; MOUSE;

ANIMALS; ATHEROSCLEROSIS; CELL NUCLEUS; FOAM CELLS; HEPARIN; HISTONES; INFLAMMATION; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; MACROPHAGES; MICE; SEPHAROSE;

EID: 79952116030     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009884     Document Type: Article

References (22)

1. Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ (1997) Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389: 251-260.
2. Courvalin JC, Dumontier M, Bornens M (1982) Solubilization of nuclear structures by the polyanion heparin. J Biol Chem 257: 456-463.
3. Pereira LF, Marco FM, Boimorto R, Caturla A, Bustos A, et al. (1994) Histones interact with anionic phospholipids with high avidity; its relevance for the binding of histone-antihistone immune complexes. Clin Exp Immunol 97: 175-180.
4. Gonias SL, Pasqua JJ, Greenberg C, Pizzo SV (1985) Precipitation of fibrinogen, fibrinogen degradation products and fibrin monomer by histone H3. Thromb Res 39: 97-116.
5. Pemberton AD, Brown JK, Inglis NF (2010) Proteomic identification of interactions between histones and plasma proteins: implications for cytoprotection. Proteomics, in press.
6. Skrzydlewski Z (1976) Low-density lipoprotein complexes with histones. Acta Biol Acad Sci Hung 27: 291-297.
7. Skrzydlewski Z, Worowski K (1977) Formation of insoluble low density lipoprotein (LDL) complexes with basic proteins in vitro and in walls of arteries changed by atheromatosis. Bull Acad Pol Sci Biol 25: 70-77.
8. Koopman R, Schaart G, Hesselink MK (2001) Optimisation of oil red O staining permits combination with immunofluorescence and automated quantification of lipids. Histochem Cell Biol 116: 63-68.
9. Williams KJ, Tabas I (1995) The response-to-retention hypothesis of early atherogenesis. Arterioscler Thromb Vasc Biol 15: 551-561.
10. Tran-Lundmark K, Tran PK, Paulsson-Berne G, Friden V, Soininen R, et al. (2008) Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation. Circ Res 103: 43-52.
11. Capila I, Linhardt RJ (2002) Heparin-protein interactions. Angew Chem Int Ed Engl 41: 391-412.
12. Weisgraber KH, Rall SC, Jr. (1987) Human apolipoprotein B-100 heparinbinding sites. J Biol Chem 262: 11097-11103.
13. Gustafsson M, Levin M, Skalen K, Perman J, Friden V, et al. (2007) Retention of low-density lipoprotein in atherosclerotic lesions of the mouse: evidence for a role of lipoprotein lipase. Circ Res 101: 777-783.
14. Henriquez JP, Casar JC, Fuentealba L, Carey DJ, Brandan E (2002) Extracellular matrix histone H1 binds to perlecan, is present in regenerating skeletal muscle and stimulates myoblast proliferation. J Cell Sci 115: 2041-2051.
15. Bilozur ME, Biswas C (1990) Identification and characterization of heparan sulfate-binding proteins from human lung carcinoma cells. J Biol Chem 265: 19697-19703.
16. Watson K, Gooderham NJ, Davies DS, Edwards RJ (1999) Nucleosomes bind to cell surface proteoglycans. J Biol Chem 274: 21707-21713.
17. Omenn GS, States DJ, Adamski M, Blackwell TW, Menon R, et al. (2005) Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database. Proteomics 5: 3226-3245.
18. Wilson PW (2008) Evidence of systemic inflammation and estimation of coronary artery disease risk: a population perspective. Am J Med 121: S15-20.
19. van Leuven SI, Franssen R, Kastelein JJ, Levi M, Stroes ES, et al. (2008) Systemic inflammation as a risk factor for atherothrombosis. Rheumatology (Oxford) 47: 3-7.
20. Xu J, Zhang X, Pelayo R, Monestier M, Ammollo CT, et al. (2009) Extracellular histones are major mediators of death in sepsis. Nat Med 15: 1318-1321.
21. Zheng X, Wu SL, Hincapie M, Hancock WS (2009) Study of the human plasma proteome of rheumatoid arthritis. J Chromatogr A 1216: 3538-3545.
22. Galkina E, Ley K (2009) Immune and inflammatory mechanisms of atherosclerosis (*). Annu Rev Immunol 27: 165-197.