-
1
-
-
14844292593
-
Blood coagulation and its regulation by anticoagulant pathways: Genetic pathogenesis of bleeding and thrombotic diseases
-
Dahlback B. Blood coagulation and its regulation by anticoagulant pathways: genetic pathogenesis of bleeding and thrombotic diseases. J Intern Med. 2005;257:209-223.
-
(2005)
J Intern Med
, vol.257
, pp. 209-223
-
-
Dahlback, B.1
-
2
-
-
0041317307
-
Congenital Hemorrhagic Disorders: New Insights into the Pathophysiology and Treatment of Hemophilia
-
Hedner U, Ginsburg D, Lusher JM, High KA. Congenital Hemorrhagic Disorders: New Insights into the Pathophysiology and Treatment of Hemophilia. Hematology Am Soc Hematol Educ Program. 2000: 241-265.
-
(2000)
High KA
, pp. 241-265
-
-
Hedner, U.1
Ginsburg, D.2
Lusher, J.M.3
-
3
-
-
0031785486
-
Occurrence of hemophilia in the United States. The Hemophilia Surveillance System Project Investigators
-
Soucie JM, Evatt B, Jackson D. Occurrence of hemophilia in the United States. The Hemophilia Surveillance System Project Investigators. Am J Hematol. 1998;59:288-294.
-
(1998)
Am J Hematol
, vol.59
, pp. 288-294
-
-
Soucie, J.M.1
Evatt, B.2
Jackson, D.3
-
6
-
-
0006351320
-
Inherited hemorrhagic disorders
-
In: Colman W, Hirsh J, Marder V, Clowes A, George J, editors, 4th ed. Philadelphia: Lippincott Williams & Willkins
-
Arun B, Kessler C. Inherited hemorrhagic disorders. In: Colman W, Hirsh J, Marder V, Clowes A, George J, editors. Hemostasis and thrombosis. 4th ed. Philadelphia: Lippincott Williams & Willkins, 2001:815-825.
-
(2001)
Hemostasis and Thrombosis
, pp. 815-825
-
-
Arun, B.1
Kessler, C.2
-
7
-
-
33749822056
-
Evidence for the benefits of prophylaxis in the management of hemophilia A
-
Hoots WK, Nugent DJ. Evidence for the benefits of prophylaxis in the management of hemophilia A. Thromb Haemost. 2006;96:433-440.
-
(2006)
Thromb Haemost
, vol.96
, pp. 433-440
-
-
Hoots, W.K.1
Nugent, D.J.2
-
9
-
-
33845754008
-
Defining 'full-length' recombinant factor VIII: A comparative structural analysis
-
Jankowski MA, Patel H, Rouse JC, Marzilli LA, Weston SB, Sharpe PJ. Defining 'full-length' recombinant factor VIII: a comparative structural analysis. Haemophilia. 2007;13:30-37.
-
(2007)
Haemophilia
, vol.13
, pp. 30-37
-
-
Jankowski, M.A.1
Patel, H.2
Rouse, J.C.3
Marzilli, L.A.4
Weston, S.B.5
Sharpe, P.J.6
-
10
-
-
0031059825
-
Recombinant, B-domain deleted factor VIII (r-VIII SQ): Pharmacokinetics and initial safety aspects in hemophilia A patients
-
Fijnvandraat K, Berntorp E, ten Cate JW, et al. Recombinant, B-domain deleted factor VIII (r-VIII SQ): pharmacokinetics and initial safety aspects in hemophilia A patients. Thromb Haemost. 1997;77:298-302.
-
(1997)
Thromb Haemost
, vol.77
, pp. 298-302
-
-
Fijnvandraat, K.1
Berntorp, E.2
ten Cate, J.W.3
-
11
-
-
0017754787
-
Stabilization of factor VIII in plasma by the von Willebrand factor. Studies on posttransfusion and dissociated factor VIII and in patients with von Willebrand's disease
-
Weiss HJ, Sussman, II, Hoyer LW. Stabilization of factor VIII in plasma by the von Willebrand factor. Studies on posttransfusion and dissociated factor VIII and in patients with von Willebrand's disease. J Clin Invest. 1977;60:390-404.
-
(1977)
J Clin Invest
, vol.60
, pp. 390-404
-
-
Weiss, H.J.1
Sussman, I.I.2
Hoyer, L.W.3
-
12
-
-
56649091115
-
Barriers to primary prophylaxis in haemophilic children: The issue of the venous access
-
Santagostino E, Mancuso ME. Barriers to primary prophylaxis in haemophilic children: the issue of the venous access. Blood Transfus. 2008;6:S12-S16.
-
(2008)
Blood Transfus
, vol.6
-
-
Santagostino, E.1
Mancuso, M.E.2
-
13
-
-
0038170070
-
Development of improved factor VIII molecules and new gene transfer approaches for hemophilia A
-
Saenko EL, Ananyeva NM, Moayeri M, Ramezani A, Hawley RG. Development of improved factor VIII molecules and new gene transfer approaches for hemophilia A. Curr Gene Ther. 2003;3:27-41.
-
(2003)
Curr Gene Ther
, vol.3
, pp. 27-41
-
-
Saenko, E.L.1
Ananyeva, N.M.2
Moayeri, M.3
Ramezani, A.4
Hawley, R.G.5
-
14
-
-
33646254385
-
Current opinion on inhibitor treatment options
-
Mathew P. Current opinion on inhibitor treatment options. Semin Hematol. 2006;43:S8-S13.
-
(2006)
Semin Hematol
, vol.43
-
-
Mathew, P.1
-
15
-
-
0031743928
-
A randomized, double-blind comparison of two dosage levels of recombinant factor VIIa in the treatment of joint, muscle and mucocutaneous haemorrhages in persons with haemophilia A and B, with and without inhibitors. rFVIIa Study Group
-
Lusher JM, Roberts HR, Davignon G, et al. A randomized, double-blind comparison of two dosage levels of recombinant factor VIIa in the treatment of joint, muscle and mucocutaneous haemorrhages in persons with haemophilia A and B, with and without inhibitors. rFVIIa Study Group. Haemophilia. 1998;4:790-798.
-
(1998)
Haemophilia
, vol.4
, pp. 790-798
-
-
Lusher, J.M.1
Roberts, H.R.2
Davignon, G.3
-
16
-
-
0037246119
-
Inhibitor treatment: State of the art
-
Shapiro A. Inhibitor treatment: state of the art. Dis Mon. 2003;49: 22-38.
-
(2003)
Dis Mon
, vol.49
, pp. 22-38
-
-
Shapiro, A.1
-
18
-
-
15244340408
-
Treatment of acquired hemophilia by the Bonn-Malmo Protocol: Documentation of an in vivo immunomodulating concept
-
Zeitler H, Ulrich-Merzenich G, Hess L, et al. Treatment of acquired hemophilia by the Bonn-Malmo Protocol: documentation of an in vivo immunomodulating concept. Blood. 2005;105:2287-2293.
-
(2005)
Blood
, vol.105
, pp. 2287-2293
-
-
Zeitler, H.1
Ulrich-Merzenich, G.2
Hess, L.3
-
20
-
-
59449097322
-
How we treat a hemophilia A patient with a factor VIII inhibitor
-
Kempton CL, White GC 2nd. How we treat a hemophilia A patient with a factor VIII inhibitor. Blood. 2009;113:11-17.
-
(2009)
Blood
, vol.113
, pp. 11-17
-
-
Kempton, C.L.1
White II, G.C.2
-
21
-
-
35148857177
-
Factor eight inhibitor bypass activity (FEIBA) in the management of bleeds in hemophilia patients with high-titer inhibitors
-
Tjonnfjord GE, Holme PA. Factor eight inhibitor bypass activity (FEIBA) in the management of bleeds in hemophilia patients with high-titer inhibitors. Vasc Health Risk Manag. 2007;3:527-531.
-
(2007)
Vasc Health Risk Manag
, vol.3
, pp. 527-531
-
-
Tjonnfjord, G.E.1
Holme, P.A.2
-
22
-
-
0023763216
-
Successful use of recombinant factor VIIa in patient with severe haemophilia A during synovectomy
-
Hedner U, Glazer S, Pingel K, et al. Successful use of recombinant factor VIIa in patient with severe haemophilia A during synovectomy. Lancet. 1988;2:1193.
-
(1988)
Lancet
, vol.2
, pp. 1193
-
-
Hedner, U.1
Glazer, S.2
Pingel, K.3
-
23
-
-
0033758876
-
Efficacy and safety of recombinant factor VIIa in the prophylaxis of bleeding in various surgical procedures in hemophilic patients with factor VIII and factor IX inhibitors
-
Ingerslev J. Efficacy and safety of recombinant factor VIIa in the prophylaxis of bleeding in various surgical procedures in hemophilic patients with factor VIII and factor IX inhibitors. Semin Thromb Hemost. 2000;26:425-432.
-
(2000)
Semin Thromb Hemost
, vol.26
, pp. 425-432
-
-
Ingerslev, J.1
-
24
-
-
18944386159
-
A study of the pharmacokinetics and safety of recombinant activated factor VII in healthy Caucasian and Japanese subjects
-
Fridberg MJ, Hedner U, Roberts HR, Erhardtsen E. A study of the pharmacokinetics and safety of recombinant activated factor VII in healthy Caucasian and Japanese subjects. Blood Coagul Fibrinolysis. 2005;16:259-266.
-
(2005)
Blood Coagul Fibrinolysis
, vol.16
, pp. 259-266
-
-
Fridberg, M.J.1
Hedner, U.2
Roberts, H.R.3
Erhardtsen, E.4
-
25
-
-
0028232368
-
Pharmacokinetics and pharmacodynamics of recombinant factor VIIa
-
Lindley CM, Sawyer WT, Macik BG, et al. Pharmacokinetics and pharmacodynamics of recombinant factor VIIa. Clin Pharmacol Ther. 1994;55:638-648.
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 638-648
-
-
Lindley, C.M.1
Sawyer, W.T.2
Macik, B.G.3
-
27
-
-
17144437423
-
Home treatment of mild to moderate bleeding episodes using recombinant factor VIIa (Novoseven) in haemophiliacs with inhibitors
-
Key NS, Aledort LM, Beardsley D, et al. Home treatment of mild to moderate bleeding episodes using recombinant factor VIIa (Novoseven) in haemophiliacs with inhibitors. J Thromb Haemost. 1998;80: 912-918.
-
(1998)
J Thromb Haemost
, vol.80
, pp. 912-918
-
-
Key, N.S.1
Aledort, L.M.2
Beardsley, D.3
-
28
-
-
33646147385
-
Strategies towards a longer acting factor VIII
-
Gale EL, Pipe SW. Strategies towards a longer acting factor VIII. Haemophilia. 2006;12 Suppl 3:42-51.
-
(2006)
Haemophilia
, vol.12
, Issue.SUPPL. 3
, pp. 42-51
-
-
Gale, E.L.1
Pipe, S.W.2
-
29
-
-
2342666603
-
An engineered interdomain disulfide bond stabilizes human blood coagulation factor VIIIa
-
Gale AJ, Pellequer JL. An engineered interdomain disulfide bond stabilizes human blood coagulation factor VIIIa. J Thromb Haemost. 2003;1:1966-1971.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 1966-1971
-
-
Gale, A.J.1
Pellequer, J.L.2
-
30
-
-
33646765242
-
Intrinsic stability and functional properties of disulfide bond-stabilized coagulation factor VIIIa variants
-
Gale AJ, Radtke KP, Cunningham MA, Chamberlain D, Pellequer JL, Griffin JH. Intrinsic stability and functional properties of disulfide bond-stabilized coagulation factor VIIIa variants. J Thromb Haemost. 2006;4:1315-2132.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 1315-2132
-
-
Gale, A.J.1
Radtke, K.P.2
Cunningham, M.A.3
Chamberlain, D.4
Pellequer, J.L.5
Griffin, J.H.6
-
31
-
-
0030664471
-
Characterization of a genetically engineered inactivation-resistant coagulation factor VIIIa
-
Pipe SW, Kaufman RJ. Characterization of a genetically engineered inactivation-resistant coagulation factor VIIIa. Proc Natl Acad Sci U S A. 1997;94:11851-11856.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 11851-11856
-
-
Pipe, S.W.1
Kaufman, R.J.2
-
32
-
-
77955492929
-
Rational design of a fully active, longacting PEGylated factor VIII for hemophilia A treatment
-
Mei B, Pan C, Jiang H, et al. Rational design of a fully active, longacting PEGylated factor VIII for hemophilia A treatment. Blood.
-
Blood
-
-
Mei, B.1
Pan, C.2
Jiang, H.3
-
33
-
-
38949118588
-
Site-specific PEGylation of rFVIII results in prolonged in vivo efficacy
-
P-T-022
-
Murphy JE, Pan C, Barnett T, et al. Site-specific PEGylation of rFVIII results in prolonged in vivo efficacy. J Thromb Haemost. 2007;5: P-T-022.
-
(2007)
J Thromb Haemost
, vol.5
-
-
Murphy, J.E.1
Pan, C.2
Barnett, T.3
-
34
-
-
38949196337
-
Biological activity of PEGylated factor VIII
-
P-T-026
-
Regan LM, Jiang X, Ramsey P, et al. Biological activity of PEGylated factor VIII. J Thromb Haemost. 2007;5:P-T-026.
-
(2007)
J Thromb Haemost
, vol.5
-
-
Regan, L.M.1
Jiang, X.2
Ramsey, P.3
-
35
-
-
38949084506
-
PEGylation protects factor VIII from the inhibition of antibody inhibitors
-
P-T-036
-
Tang L, Pan C, Atwal H, et al. PEGylation protects factor VIII from the inhibition of antibody inhibitors. J Thromb Haemost. 2007;5: P-T-036.
-
(2007)
J Thromb Haemost
, vol.5
-
-
Tang, L.1
Pan, C.2
Atwal, H.3
-
36
-
-
33847054740
-
A variant of recombinant factor VIIa with enhanced procoagulant and antifibrinolytic activities in an in vitro model of hemophilia
-
Allen GA, Persson E, Campbell RA, Ezban M, Hedner U, Wolberg AS. A variant of recombinant factor VIIa with enhanced procoagulant and antifibrinolytic activities in an in vitro model of hemophilia. Arterioscler Thromb Vasc Biol. 2007;27:683-689.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 683-689
-
-
Allen, G.A.1
Persson, E.2
Campbell, R.A.3
Ezban, M.4
Hedner, U.5
Wolberg, A.S.6
-
37
-
-
55549105470
-
Generation and biochemical characterization of glycoPEGylated factor VIIa derivatives
-
Stennicke HR, Ostergaard H, Bayer RJ, et al. Generation and biochemical characterization of glycoPEGylated factor VIIa derivatives. J Thromb Haemost. 2008;100:920-928.
-
(2008)
J Thromb Haemost
, vol.100
, pp. 920-928
-
-
Stennicke, H.R.1
Ostergaard, H.2
Bayer, R.J.3
-
38
-
-
53449102958
-
Use of albumin fusion technology to prolong the half-life of recombinant factor VIIa
-
Schulte S. Use of albumin fusion technology to prolong the half-life of recombinant factor VIIa. Thromb Res. 2008;122:S14-S19.
-
(2008)
Thromb Res
, vol.122
-
-
Schulte, S.1
-
39
-
-
43549100662
-
Concept and clinical evaluation of carrier-mediated anticancer agents
-
Zamboni WC. Concept and clinical evaluation of carrier-mediated anticancer agents. Oncologist. 2008;13:248-260.
-
(2008)
Oncologist
, vol.13
, pp. 248-260
-
-
Zamboni, W.C.1
-
40
-
-
57049155542
-
Liposomes for targeted delivery of antithrombotic drugs
-
Elbayoumi TA, Torchilin VP. Liposomes for targeted delivery of antithrombotic drugs. Expert Opin Drug Deliv. 2008;5:1185-1198.
-
(2008)
Expert Opin Drug Deliv
, vol.5
, pp. 1185-1198
-
-
Elbayoumi, T.A.1
Torchilin, V.P.2
-
41
-
-
0037681850
-
Pharmacokinetics of pegylated liposomal Doxorubicin: Review of animal and human studies
-
Gabizon A, Shmeeda H, Barenholz Y. Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies. Clin Pharmacokinet. 2003;42:419-436.
-
(2003)
Clin Pharmacokinet
, vol.42
, pp. 419-436
-
-
Gabizon, A.1
Shmeeda, H.2
Barenholz, Y.3
-
42
-
-
0028349925
-
Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes
-
Gabizon A, Catane R, Uziely B, et al. Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res. 1994; 54:987-992.
-
(1994)
Cancer Res
, vol.54
, pp. 987-992
-
-
Gabizon, A.1
Catane, R.2
Uziely, B.3
-
43
-
-
0027162899
-
Prolongation of the circulation time of doxorubicin encapsulated in liposomes containing a polyethylene glycol-derivatized phospholipid: Pharmacokinetic studies in rodents and dogs
-
Gabizon AA, Barenholz Y, Bialer M. Prolongation of the circulation time of doxorubicin encapsulated in liposomes containing a polyethylene glycol-derivatized phospholipid: pharmacokinetic studies in rodents and dogs. Pharm Res. 1993;10:703-708.
-
(1993)
Pharm Res
, vol.10
, pp. 703-708
-
-
Gabizon, A.A.1
Barenholz, Y.2
Bialer, M.3
-
44
-
-
0025341615
-
Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes
-
Klibanov AL, Maruyama K, Torchilin VP, Huang L. Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Lett. 1990;268:235-237.
-
(1990)
FEBS Lett
, vol.268
, pp. 235-237
-
-
Klibanov, A.L.1
Maruyama, K.2
Torchilin, V.P.3
Huang, L.4
-
45
-
-
20444503381
-
Factor VIII efficient and specific non-covalent binding to PEGylated liposomes enables prolongation of its circulation time and haemostatic efficacy
-
Baru M, Carmel-Goren L, Barenholz Y, et al. Factor VIII efficient and specific non-covalent binding to PEGylated liposomes enables prolongation of its circulation time and haemostatic efficacy. J Thromb Haemost. 2005;93:1061-1068.
-
(2005)
J Thromb Haemost
, vol.93
, pp. 1061-1068
-
-
Baru, M.1
Carmel-Goren, L.2
Barenholz, Y.3
-
46
-
-
69949106861
-
Enhancement of haemostatic efficacy of plasma-derived FVIII by formulation with PEGylated liposomes
-
Dayan I, Robinson M, Baru M. Enhancement of haemostatic efficacy of plasma-derived FVIII by formulation with PEGylated liposomes. Haemophilia. 2009;15:1006-1013.
-
(2009)
Haemophilia
, vol.15
, pp. 1006-1013
-
-
Dayan, I.1
Robinson, M.2
Baru, M.3
-
47
-
-
43149122484
-
Enhancement of factor VIIa haemostatic efficacy by formulation with PEGylated liposomes
-
Yatuv R, Dayan I, Carmel-Goren L, et al. Enhancement of factor VIIa haemostatic efficacy by formulation with PEGylated liposomes. Haemophilia. 2008;14:476-483.
-
(2008)
Haemophilia
, vol.14
, pp. 476-483
-
-
Yatuv, R.1
Dayan, I.2
Carmel-Goren, L.3
-
48
-
-
61849169007
-
Binding of proteins to PEGylated liposomes and improvement of G-CSF efficacy in mobilization of hematopoietic stem cells
-
Yatuv R, Carmel-Goren L, Dayan I, Robinson M, Baru M. Binding of proteins to PEGylated liposomes and improvement of G-CSF efficacy in mobilization of hematopoietic stem cells. J Control Release. 2009;135:44-50.
-
(2009)
J Control Release
, vol.135
, pp. 44-50
-
-
Yatuv, R.1
Carmel-Goren, L.2
Dayan, I.3
Robinson, M.4
Baru, M.5
-
49
-
-
33845241302
-
Prolonged bleedingfree period following prophylactic infusion of recombinant factor VIII reconstituted with pegylated liposomes
-
Spira J, Plyushch OP, Andreeva TA, Andreev Y. Prolonged bleedingfree period following prophylactic infusion of recombinant factor VIII reconstituted with pegylated liposomes. Blood. 2006;108:3668-3673.
-
(2006)
Blood
, vol.108
, pp. 3668-3673
-
-
Spira, J.1
Plyushch, O.P.2
Andreeva, T.A.3
Andreev, Y.4
-
50
-
-
70350500718
-
Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice
-
Pan J, Liu T, Kim JY, et al. Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice. Blood. 2009;114:2802-2811.
-
(2009)
Blood
, vol.114
, pp. 2802-2811
-
-
Pan, J.1
Liu, T.2
Kim, J.Y.3
-
51
-
-
34447118419
-
Liposomal approach towards the development of a longeracting factor VIII
-
Powell JS. Liposomal approach towards the development of a longeracting factor VIII. Haemophilia. 2007;13:23-28.
-
(2007)
Haemophilia
, vol.13
, pp. 23-28
-
-
Powell, J.S.1
-
52
-
-
51349110498
-
Evaluation of liposomal dose in recombinant factor VIII reconstituted with pegylated liposomes for the treatment of patients with severe haemophilia A
-
Spira J, Plyushch OP, Andreeva TA, Khametova RN. Evaluation of liposomal dose in recombinant factor VIII reconstituted with pegylated liposomes for the treatment of patients with severe haemophilia A. J Thromb Haemost. 2008;100:429-434.
-
(2008)
J Thromb Haemost
, vol.100
, pp. 429-434
-
-
Spira, J.1
Plyushch, O.P.2
Andreeva, T.A.3
Khametova, R.N.4
-
53
-
-
38349083504
-
Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A
-
Powell JS, Nugent DJ, Harrison JA, et al. Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A. J Thromb Haemost. 2008;6:277-283.
-
(2008)
J Thromb Haemost
, vol.6
, pp. 277-283
-
-
Powell, J.S.1
Nugent, D.J.2
Harrison, J.A.3
-
54
-
-
51249103798
-
Infusion rates of recombinant FVIII-FS with PEGylated liposomes in haemophilia A
-
Martinowitz U, Lalezari S, Luboshitz J, Lubetsky A, Spira J. Infusion rates of recombinant FVIII-FS with PEGylated liposomes in haemophilia A. Haemophilia. 2008;14:1122-1124.
-
(2008)
Haemophilia
, vol.14
, pp. 1122-1124
-
-
Martinowitz, U.1
Lalezari, S.2
Luboshitz, J.3
Lubetsky, A.4
Spira, J.5
-
55
-
-
28244466864
-
Complement activation-related pseudoallergy: A new class of drug-induced acute immune toxicity
-
Szebeni J. Complement activation-related pseudoallergy: a new class of drug-induced acute immune toxicity. Toxicology. 2005;216:106-121.
-
(2005)
Toxicology
, vol.216
, pp. 106-121
-
-
Szebeni, J.1
-
56
-
-
78049295599
-
Safety, pharmacokinetics and efficacy of factor VIIa formulated with PEGylated liposomes in haemophilia A patients with inhibitors to factor VIII. An open label, exploratory, cross over, phase I/II study
-
In Press
-
Spira J, Plyushch OP, Zozulya N, et al. Safety, pharmacokinetics and efficacy of factor VIIa formulated with PEGylated liposomes in haemophilia A patients with inhibitors to factor VIII. An open label, exploratory, cross over, phase I/II study. Haemophilia. 2010; In Press.
-
(2010)
Haemophilia
-
-
Spira, J.1
Plyushch, O.P.2
Zozulya, N.3
-
57
-
-
76149134362
-
Enhancement of the efficacy of therapeutic proteins by formulation with PEGylated liposomes; a case of FVIII, FVIIa and G-CSF
-
Yatuv R, Robinson M, Dayan I, Baru M. Enhancement of the efficacy of therapeutic proteins by formulation with PEGylated liposomes; a case of FVIII, FVIIa and G-CSF. Expert Opin Drug Deliv. 2010;7:187-201.
-
(2010)
Expert Opin Drug Deliv
, vol.7
, pp. 187-201
-
-
Yatuv, R.1
Robinson, M.2
Dayan, I.3
Baru, M.4
-
59
-
-
33745829014
-
The leak stops here: Platelets as delivery vehicles for coagulation factors
-
High KA. The leak stops here: platelets as delivery vehicles for coagulation factors. J Clin Invest. 2006;116:1840-1842.
-
(2006)
J Clin Invest
, vol.116
, pp. 1840-1842
-
-
High, K.A.1
-
60
-
-
0032916792
-
Inhibitors in German hemophilia A patients treated with a double virus inactivated factor VIII concentrate bind to the C2 domain of FVIII light chain
-
Laub R, Di Giambattista M, Fondu P, et al. Inhibitors in German hemophilia A patients treated with a double virus inactivated factor VIII concentrate bind to the C2 domain of FVIII light chain. J Thromb Haemost. 1999;81:39-44.
-
(1999)
J Thromb Haemost
, vol.81
, pp. 39-44
-
-
Laub, R.1
di Giambattista, M.2
Fondu, P.3
-
61
-
-
0031726179
-
Modification of factor VIII in therapeutic concentrates after virus inactivation by solvent-detergent and pasteurisation
-
Raut S, Di Giambattista M, Bevan SA, Hubbard AR, Barrowcliffe TW, Laub R. Modification of factor VIII in therapeutic concentrates after virus inactivation by solvent-detergent and pasteurisation. J Thromb Haemost. 1998;80:624-631.
-
(1998)
J Thromb Haemost
, vol.80
, pp. 624-631
-
-
Raut, S.1
di Giambattista, M.2
Bevan, S.A.3
Hubbard, A.R.4
Barrowcliffe, T.W.5
Laub, R.6
-
62
-
-
0027299669
-
Preclinical toxicology study of liposome encapsulated doxorubicin (TLC D-99): Comparison with doxorubicin and empty liposomes in mice and dogs
-
Kanter PM, Bullard GA, Pilkiewicz FG, Mayer LD, Cullis PR, Pavelic ZP. Preclinical toxicology study of liposome encapsulated doxorubicin (TLC D-99): comparison with doxorubicin and empty liposomes in mice and dogs. In Vivo. 1993;7:85-95.
-
(1993)
In Vivo
, vol.7
, pp. 85-95
-
-
Kanter, P.M.1
Bullard, G.A.2
Pilkiewicz, F.G.3
Mayer, L.D.4
Cullis, P.R.5
Pavelic, Z.P.6
|