Glucocerebrosidase gene has an alternative upstream promoter, which has features and expression characteristic of housekeeping genes

Blood Cells, Molecules, and Diseases

Volumn 46, Issue 3, 2011, Pages 239-245

  Svobodová, Eva ^a   Mrázová, Lenka ^a   Lukšan, Ondřej ^b   Elstein, Deborah ^c   Zimran, Ari ^c   Stolnaya, Larisa ^a   Minks, Jakub ^a,d   Eberová, Jitka ^b,e   Dvořáková, Lenka ^a   Jirsa, Milan ^b   Hřebíček, Martin ^a  

^a Charles University in Prague and General University Hospital in Prague   (Czech Republic)

^b INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^c SHAARE ZEDEK MEDICAL CENTER   (Israel)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^e Genetwister Technologies BV   (Netherlands)

Author keywords

Alternative promoter; Gaucher disease; Gene expression; Glucocerebrosidase; Housekeeping gene

Indexed keywords

BETA ACTIN; GLUCOSYLCERAMIDASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LUCIFERASE;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL STRAIN HEPG2; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DIAGNOSTIC TEST ACCURACY STUDY; DNA DETERMINATION; GAUCHER DISEASE; GENE CONSTRUCT; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC STABILITY; HOMOZYGOSITY; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TATA BOX; TRANSCRIPTION INITIATION;

BASE SEQUENCE; BINDING SITES; CONSENSUS SEQUENCE; CPG ISLANDS; GAUCHER DISEASE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE ORDER; GENES, REPORTER; GLUCOSYLCERAMIDASE; HEP G2 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; SEQUENCE ALIGNMENT; SEQUENCE DELETION; TRANSCRIPTION INITIATION SITE;

EID: 79952106214     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2010.12.011     Document Type: Article

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