Expression and distribution of immunoglobulin G and its receptors in the human nervous system

International Journal of Biochemistry and Cell Biology

Volumn 43, Issue 4, 2011, Pages 556-563

  Niu, Na ^a,b   Zhang, Jie ^a   Guo, Yong ^b,c   Zhao, Yingying ^b   Korteweg, Christine ^d   Gu, Jiang ^b,d  

^a WEIFANG MEDICAL UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c FUWAI HOSPITAL   (China)

^d SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

Human; IgG receptor; Immunoglobulin G; Nervous system; Neuro immune crosstalk; Neuron

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; BETA ACTIN; CD16 ANTIGEN; CD19 ANTIBODY; CONSTANT REGIONS OF HUMAN IMMUNOGLOBULIN G1; FC RECEPTOR; FC RECEPTOR I; FC RECEPTOR IIA; FCRN PROTEIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; MESSENGER RNA; PROTEIN; RAG1 PROTEIN; RAG2 PROTEIN; UNCLASSIFIED DRUG; VDJ SEGMENT OF IMMUNOGLOBULIN GAMMA;

ANTIBODY DETECTION; ANTIBODY PRODUCTION; ARTICLE; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CONTROLLED STUDY; DENDRITE; DENTATE GYRUS; FRONTAL LOBE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN PRODUCTION; IMMUNOREACTIVITY; INFERIOR MESENTERIC GANGLION; MEDULLA OBLONGATA; MICROGLIA; NERVE CELL; OCCIPITAL CORTEX; PERIPHERAL NERVOUS SYSTEM; PONS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PURKINJE CELL; QUANTITATIVE ANALYSIS; SPINAL CORD DORSAL HORN; SPINAL CORD VENTRAL HORN; STELLATE CELL; TEMPORAL CORTEX; VASCULAR ENDOTHELIUM;

CENTRAL NERVOUS SYSTEM; GENE EXPRESSION REGULATION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; PERIPHERAL NERVOUS SYSTEM; RECEPTORS, FC; RECEPTORS, IGG; RNA, MESSENGER;

EID: 79952101057     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.12.012     Document Type: Article

References (35)

1. F. Aloisi Immune function of microglia Glia 36 2001 165 179 [PubMed:2139103] (Pubitemid 33055905)
2. T. Andoh, and Y. Kuraishi Direct action of immunoglobulin G on primary sensory neurons through Fc gamma receptor I FASEB J 18 2004 182 184 [PubMed:14630707]
3. T. Aoki, K. Tashiro, S. Miyatake, T. Nakano, Y. Oda, and H. Kikuchi Expression of the RAG-2 gene in murine central nervous system tumor cell lines Biochem Biophys Res Commun 181 1991 151 158 [PubMed:1683534]
4. T.V. Arumugam, S.C. Tang, J.D. Lathia, A. Cheng, M.R. Mughal, and S. Chigurupati Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death Proc Natl Acad Sci USA 104 2007 14104 14109 [PubMed:17715065] (Pubitemid 350003342)
5. A. Bouloukos, J. Lekakis, J. Michael, and A. Kalofoutis Immunoglobulins in cerebrospinal fluid in various neurologic disorders Clin Chem 26 1980 115 116 [PubMed:7356542] (Pubitemid 10175869)
6. M.J. Carson, J.M. Doose, B. Melchior, C.D. Schmid, and C.C. Ploix CNS immune privilege: hiding in plain sight Immunol Rev 213 2006 48 65 [PubMed:16972896] (Pubitemid 44401493)
7. Z. Chen, and J. Gu Immunoglobulin G expression in carcinomas and cancer cell lines FASEB J 21 2007 2931 2938 [PubMed:17475920] (Pubitemid 47372759)
8. J.J. Chun, D.G. Schatz, M.A. Oettinger, R. Jaenisch, and D. Baltimore The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system Cell 64 1991 189 200 [PubMed:1986864] (Pubitemid 121001150)
9. R. Deane, A. Sagare, K. Hamm, M. Parisi, B. LaRue, and H. Guo IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor J Neurosci 25 2005 11495 11503 [PubMed:16354907] (Pubitemid 43102486)
10. R. Deng, M. Lu, C. Korteweg, Z. Gao, M.A. McNutt, and J. Ye Distinctly different expression of cytokines and chemokines in the lungs of two H5N1 avian influenza patients J Pathol 216 2008 328 336 [PubMed:18788084]
11. R.H. Fabian Uptake of plasma IgG by CNS motoneurons: comparison of antineuronal and normal IgG Neurology 38 1988 1775 1780 [PubMed:3185914] (Pubitemid 18265046)
12. D. Goldman, X. Song, R. Kitai, A. Casadevall, M.L. Zhao, and S.C. Lee Cryptococcus neoformans induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta in human microglia: role of specific antibody and soluble capsular polysaccharide Infect Immun 69 2001 1808 1815 [PubMed:11179358] (Pubitemid 32187640)
13. J. Huang, X. Sun, Y. Mao, X. Zhu, P. Zhang, and L. Zhang Expression of immunoglobulin gene with classical V-(D)-J rearrangement in mouse brain neurons Int J Biochem Cell Biol 40 2008 1604 1615 [PubMed:18243769]
14. R.E. Hulse, W.G. Swenson, P.E. Kunkler, D.M. White, and R.P. Kraig Monomeric IgG is neuroprotective via enhancing microglial recycling endocytosis and TNF-alpha J Neurosci 28 2008 12199 12211 [PubMed:19020014]
15. P.G. Kennedy, R.P. Lisak, and M.C. Raff Cell type-specific markers for human glial and neuronal cells in culture Lab Invest 43 1980 342 351 [PubMed:6160316] (Pubitemid 10008960)
16. M. Kerschensteiner, E. Meinl, and R. Hohlfeld Neuro-immune crosstalk in CNS diseases Neuroscience 158 2009 1122 1132 [PubMed:18848864]
17. H.D. Liu, H. Zheng, M. Li, D.S. Hu, M. Tang, and Y. Cao Upregulated expression of kappa light chain by Epstein-Barr virus encoded latent membrane protein 1 in nasopharyngeal carcinoma cells via NF-kappaB and AP-1 pathways Cell Signal 19 2007 419 427 [PubMed:16979873] (Pubitemid 46001832)
18. E. Mix, R. Goertsches, and U.K. Zettl Immunology and neurology J Neurol 2007 254 Suppl. 2 2007 II2 II7 [PubMed:17503123]
19. H.A. Mohamed, D.R. Mosier, L.L. Zou, L. Siklos, M.E. Alexianu, and J.I. Engelhardt Immunoglobulin Fc gamma receptor promotes immunoglobulin uptake, immunoglobulin-mediated calcium increase, and neurotransmitter release in motor neurons J Neurosci Res 2002 69 2002 110 116 [PubMed:12111822] (Pubitemid 34734171)
20. M. Muramatsu, K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme Cell 102 2000 553 563 [PubMed:11007474]
21. J. Nakahara, K. Tan-Takeuchi, C. Seiwa, M. Gotoh, T. Kaifu, and A. Ujike Signaling via immunoglobulin Fc receptors induces oligodendrocyte precursor cell differentiation Dev Cell 4 2003 841 852 [PubMed:12791269] (Pubitemid 36676036)
22. N. Niu, J. Zhang, Y. Guo, C. Yang, and J. Gu Cystic fibrosis transmembrane conductance regulator expression in human spinal and sympathetic ganglia Lab Invest 89 2009 636 644 [PubMed:19333236]
23. M.A. Oettinger, D.G. Schatz, C. Gorka, and D. Baltimore RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination Science 248 1990 1517 1523 [PubMed:2360047]
24. X. Qiu, X. Zhu, L. Zhang, Y. Mao, J. Zhang, and P. Hao Human epithelial cancers secrete immunoglobulin G with unidentified specificity to promote growth and survival of tumor cells Cancer Res 63 2003 6488 6495 [PubMed:14559841] (Pubitemid 37255201)
25. M. Raghavan, and P.J. Bjorkman Fc receptors and their interactions with immunoglobulins Annu Rev Cell Dev Biol 12 1996 181 220 [PubMed:8970726] (Pubitemid 26422713)
26. H. Reiber, S. Ungefehr, and C. Jacobi The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis Mult Scler 4 1998 111 117 [PubMed:9762657] (Pubitemid 28410034)
27. D.C. Roopenian, and S. Akilesh FcRn: the neonatal Fc receptor comes of age Nat Rev Immunol 7 2007 715 725 [PubMed:17703228] (Pubitemid 47327396)
28. F. Schlachetzki, C. Zhu, and W.M. Pardridge Expression of the neonatal Fc receptor (FcRn) at the blood-brain barrier J Neurochem 81 2002 203 206 [PubMed:12067234] (Pubitemid 34808868)
29. X. Song, S. Shapiro, D.L. Goldman, A. Casadevall, M. Scharff, and S.C. Lee Fc gamma receptor I- and III-mediated macrophage inflammatory protein 1alpha induction in primary human and murine microglia Infect Immun 70 2002 5177 5184 [PubMed:12183568]
30. A. Stahlberg, P. Aman, B. Ridell, P. Mostad, and M. Kubista Quantitative real-time PCR method for detection of B-lymphocyte monoclonality by comparison of kappa and lambda immunoglobulin light chain expression Clin Chem 49 2003 51 59 [PubMed:12507960] (Pubitemid 36078553)
31. E.J. Thompson, P.G. Riches, and J. Kohn Antibody synthesis within the central nervous system: comparisons of CSF IgG indices and electrophoresis J Clin Pathol 36 1983 312 315 [PubMed:6826780] (Pubitemid 13160695)
32. M.B. Upender, J.A. Dunn, S.M. Wilson, and J.R. Naegele Immunoglobulin molecules are present in early-generated neuronal populations in the rat cerebral cortex and retina J Comp Neurol 384 1997 271 282 [PubMed:9215722] (Pubitemid 27282043)
33. C.A. Vedeler Demonstration of Fc gamma receptors on human peripheral nerve fibres J Neuroimmunol 15 1987 207 216 [PubMed:2953759] (Pubitemid 17075153)
34. J.A. Weiner, and J. Chun Maternally derived immunoglobulin light chain is present in the fetal mammalian CNS J Neurosci 17 1997 3148 3156 [PubMed:9096149] (Pubitemid 27175827)
35. Y. Zhang, and W.M. Pardridge Mediated efflux of IgG molecules from brain to blood across the blood-brain barrier J Neuroimmunol 114 2001 168 172 [PubMed:11240028] (Pubitemid 32184738)