Evaluation of effects of ethanolic extract from Platonia insignis mart, on pilocarpine-induced seizures

Journal of Biological Sciences

Volumn 10, Issue 8, 2010, Pages 747-753

  da Costa Jr , Joaquim Soares ^a,b   Feitosa, Chistiane Mendes ^c   das Graças Lopes Citó, Antonia Maria ^b   de Freitas, Rivelilson Mendes ^c   Henriques, João Antonio Pegas ^d   Saffi, Jenifer ^d  

^a UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

^b INSTITUTO FEDERAL DE EDUCAÇÃO   (Brazil)

^c FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

^d FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Ethanolic extract; Lipid peroxidation; Nitrite; P. insignis; Striatum

Indexed keywords

LIPID; NITRITE; PILOCARPINE; PLANT EXTRACT; PLATONIA INSIGNIS EXTRACT; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; LIPID PEROXIDATION; LOCOMOTION; MALE; MEDICINAL PLANT; MOTOR ACTIVITY; NONHUMAN; OXIDATIVE STRESS; PLATONIA INSIGNIS; RAT; SEIZURE; SPECTROPHOTOMETRY;

ANIMALIA; PLATONIA ESCULENTA; RATTUS; RATTUS NORVEGICUS;

EID: 79952077597     PISSN: 17273048     EISSN: 18125719     Source Type: Journal    
DOI: 10.3923/jbs.2010.747.753     Document Type: Article

References (43)

1. Acuna, U.M., N. Jancovski and E.J. Kennelly, 2009. Polyisoprenylated benzophenones from Clusiaceae: Potential drugs and lead compounds. Curr. Top. Med. Chem., 9: 1560-1580.
2. Agra, M.F., P.F. Freitas and J.M. Barbosa-Filho, 2007. Synopsis of the plants known as medicinal and poisonous in Northeast of Brazil. Rev. Bras. Farmacogn., 17: 114-140.
3. Almeida, R.N., A. Falcao, R.S.T. Diniz, L.J. Quintans-Junior and R.M. Polari et al., 1999. Methodology for evaluation of plants with central nervous system and some experimental data. Braz. J. Pharmacognosy, 80: 72-76.
4. Asakura, W., K. Matsumoto, H. Ohta and H. Watanabe, 1993. Effect of [alpha] 2-adrenergic drugs on REM sleep deprivation-induced increase in swimming activity. Pharmacol. Biochem. Behav., 46: 111-115.
5. Barros, D.O., S.M. Xavier, C.O. Barbosa, R.F. Silva and R.L. Freitas et al., 2007. Effects of the vitamin E in catalase activities in hippocampus after status epilepticus induced by pilocarpine in Wistar rats. Neurosci. Lett., 416: 227-230.
6. Boulanger, R., D. Chassagne and J. Crouzet, 1999. Free and bound flavour components of amazonian fruits. 1: Bacuri. Flavour. Frag. J., 14: 303-311.
7. Carlini, E.A., 2003. Plants and the central nervous system. Pharmacol. Biochem. Behav., 75: 501-512.
8. Castagne, V., M. Gautschi, K. Lefevre, A. Posada and P.G.H. Clarke, 1999. Relationships between neuronal death and the cellular redox status focus on the developing nervous system. Prog. Neurobiol., 59: 397-423.
9. Ciochina, R. and R.B. Grossman, 2006. Polycyclic polyprenylated acylphloroglucinols. Chem. Rev., 105: 3963-3986.
10. De Moura, D.F., J.R. De A. Silva, D.T. Ohana, M.S. De Mendonca, J.L.P. Ferreira and A.C.F. Amaral, 2008. Histological study of the leaf, bark and fruit of Vismia cayennensis. Int. J. Bot., 4: 321-325.
11. Draper, H.H. and M. Hadley, 1990. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol., 186: 421-431.
12. Freire, C.M.M., M.O.M. Marques and M. Costa, 2006. Effects of seasonal variation on the central nervous system activity of Ocimum gratissimum L. essential oil. J. Ethnopharmacol., 105: 161-166.
13. Gottlieb, M., R. Leal-Campanario, M.R. Campos-Esparza, M.V. Sanchez-Gomez and E. Alberdi et al., 2006. Neuroprotection by two polyphenols following excitotoxicity and experimental ischemia. Neurobiol. Dis., 23: 374-386.
14. Green, L.C., S.R. Tannenbaum and P. Goldman, 1981. Nitrate synthesis in the germfree and conventional rat. Science, 212: 56-58.
15. Gustafson, K.R., J.W. Blunt H.G.M. Munro, R.W. Fuller and C.T. McKee et al., 1992. HIV inhibitory natural products. The Guttiferones, HIV-inhibitoiy benzophenones from Symphonia globulifera, Garcinia livingstonei, Garcinia ovalifolia and Clusia rosea. Tetrahedron, 48: 10093-10102.
16. Halliwell, B. and J.M.C. Guttendge, 1989. Lipid Peroxidation: A Radical Chain Reaction, Free Radicals in Biology and Medicine. Clarendon Press, Oxford, pp: 188-276.
17. Halliwell, B. and J.M.C. Guttendge, 1999. Free Radicals in Biology and Medicine. Oxford Univ. Press, Oxford.
18. Harborne, J.B., H. Baxter and G.P. Moss, 1999. Phytochemical Dictionary: A Handbook of Bioactive Compounds from Plants. 2nd Edn., Taylor and Francis, London, ISBN-10: 0748406204, pp: 582-590.
19. Hosni, K., K. Msaada, M.B. Taartt, M. Hammami and B. Marzouk, 2010. Bioactive components of three Hypericum species from Tunisia: A comparative study Ind. Crop. Prod., 31: 158-163.
20. Hosseinzadeh, H., G.R. Karimi and M. Rakhshanizadeh, 2005. Anticonvulsant effect of Hypericum perforatum. Role of nitric oxide. J. Ethnopharmacol., 98: 207-208.
21. Iinuma, M., H. Tosa, T. Tanaka, S. Kanamaru and F. Asai et al., 1996. Antibacterial activity of some Garcinia benzophenone derivatives against methicillin-resistant Staphyîococcus aureus. Biol. Pharm. Bull., 19: 311-314.
22. Leite, M.P., J. Fassin Jr, E.M.F. Baziloni, R.N. Almeida, R. Mattel and J.R. Leite, 2008. Behavioral effects of essential oil of Citrus aurantium L. inhalation in rats. Rev. Bras. Farmacogn., 18: 661-666.
23. Lenta, B.N., C. Vonthron-Senecheau, B. Weniger, K.P. Devkota and J. Ngoupayo et al., 2007. Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds from Allanblackia monticola and Symphonia globulifera. Molecules, 12: 1548-1557.
24. Maczurek, A., K. Hager, M. Kenklies, M. Sharmanand R. Martins et al., 2008. Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease. Adv. Drug Deliv. Rev., 60: 1463-1470.
25. Malawska, B., 2005. New anticonvulsant agents. Curr. Top. Med. Chem., 5: 69-85.
26. Marona, H., E. Pekala, B. Filipek, D. Maciag and E. Szneler, 2001. Pharmacological properties of some aminoalkanolic derivatives of xanthone. Pharmazie, 56: 567-572.
27. Marona, H., E. Pekala, L. Antkiewicz-Michaluk, M. Walczak and E. Szneler, 2008. Anticonvulsant activity of some xanthone derivatives. Bioorganic Med. Chem., 16: 7234-7244.
28. Michiels, C., M. Raes, O. Toussaint and J. Remacle, 1994. Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radic. Biol. Med., 17: 235-248.
29. 2 and other solvents. J. Supercritical Fluids, 11: 91-102.
30. Morais, L.C.S.L., L.J. Quintans-Junior, C.I.F. Franco, J.R.G.S. Almeida and R.N. Almeida, 2004. Antiparkinsonian-like effects of Plumbago scandens on tremorine-induced tremors methodology. Pharmacol. Biochem. Behav., 79: 745-749.
31. Netto, S.M., R.W.B. Warela, M.F. Fechine, M.N. Queiroga and L.J. Quintans-Junior, 2009. Anxiolytic-like effect of Rauvolfia ligustrina Willd. ex Roem. and Schult., Apocynaceae, in the elevated plus-maze and hole-board tests. Rev. Bras. Farmacogn., 19: 888-892.
32. Nikalje, A.P.G., M. Ghodke and A. Girbane, 2011. GABA modulating agents: A brief review. Asian J. Biol. Sci., (In Press).
33. Peres, V., T.J. Nagem and F.F. de Oliveira, 2000. Tetraoxygenated naturally occurring xanthones. Phytochemistry, 55: 683-710.
34. Quintans-Junior, L.J., Almeida, J.T. Lima, X.P. Nunes and J.S. Siqueira et al., 2008. Plants with anticonvulsant properties: A review. Rev. Bras. Farmacogn., 18: 798-819.
35. Quintans-Junior, L.J., T.T. Souza, B.S. Leite, N.M.N. Lessa and L.R. Bonjardim et al., 2008. Phythochemical screening and anticonvulsant activity of Cymbopogon winterianus Jowitt (Poaceae) leaf essential oil in rodents. Phytomedecine, 15: 619-624.
36. Rauca, C., I. Wiswedel, R. Zerbe, G. Keilhoff and M. Krug, 2004. The role of superoxide dismutase and alpha-tocopherol in the development of seizures and kindling induced by pentylenetetrazol-Influence of the radical scavenger alpha-phenyl-N-tert-butyl nitrone. Brain Res., 1009: 203-212.
37. Somani, R.R., G. Kadam, R. Vohra, S. Vijayaraghavan and P.Y. Shirodkar, 2010. Studies of cns activities of some mannich bases of 1,3,4-oxadiazole. Int. J. Pharmacol., 6: 696-704.
38. Taha, A.Y., W.M. Burnham and S. Auvin, 2010. Polyunsaturated fatty acids and epilepsy. Epilepsia, 51: 1348-1358.
39. Tejada, S., C. Roca, A. Sureda, R.V. Rial, A. Gamundi and S. Esteban, 2006. Antioxidant response analysis in the brain after pilocarpine treatments. Brain Res. Bull., 69: 587-592.
40. Vyawahare, N.S., A.R. Khandelwal, V.R. Batra and A.P. Nikam, 2007. Herbal anticonvulsants. J. Herb. Med. Toxicol., 1: 9-14.
41. Wu, C.C., J.R. Weng, S.J. Won and C.N. Lin, 2005. Constituents of the pericarp of Garcinia subelliptica. J. Nat. Prod., 68: 1125-1127.
42. Wu, C.C., Y.H. Lu, B.L. Wei, S.C. Yang and S.J. Won et al., 2008. Phloroglucinols with prooxidant activity from Garcinia subelliptica. J. Nat. Prod., 71: 246-250.
43. Xavier, S.M., C.O. Barbosa, D.O. Barros, R.F. Silva, A.A. Oliveira and R.M. Freitas, 2007. Vitamin C antioxidant effects in hippocampus of adult Wistar rats after seizures and status epilepticus induced by pilocarpine. Neurosci. Lett., 420: 76-79.