-
1
-
-
19644368252
-
Adeno-associated virus vectors in clinical trials
-
Carter, B.J. Adeno-associated virus vectors in clinical trials. Hum. Gene Ther. 2005, 16, 541-550.
-
(2005)
Hum. Gene Ther
, vol.16
, pp. 541-550
-
-
Carter, B.J.1
-
2
-
-
21244441929
-
Immune responses to adeno-associated virus vectors
-
Zaiss, A.K.; Muruve, D.A. Immune responses to adeno-associated virus vectors. Curr. Gene Ther. 2005, 5, 323-331.
-
(2005)
Curr. Gene Ther
, vol.5
, pp. 323-331
-
-
Zaiss, A.K.1
Muruve, D.A.2
-
3
-
-
22644433751
-
No evidence for tumorigenesis of AAV vectors in a large-scale study in mice
-
Bell, P.; Wang, L.; Lebherz, C.; Flieder, D.B.; Bove, M.S.; Wu, D.; Gao, G.P.; Wilson, J.M.; Wivel, N.A. No evidence for tumorigenesis of AAV vectors in a large-scale study in mice. Mol. Ther. 2005, 12, 299-306.
-
(2005)
Mol. Ther
, vol.12
, pp. 299-306
-
-
Bell, P.1
Wang, L.2
Lebherz, C.3
Flieder, D.B.4
Bove, M.S.5
Wu, D.6
Gao, G.P.7
Wilson, J.M.8
Wivel, N.A.9
-
4
-
-
10944269753
-
Integration of adeno-associated virus (AAV) and recombinant AAV vectors
-
McCarty, D.M.; Young, S.M., Jr.; Samulski, R.J. Integration of adeno-associated virus (AAV) and recombinant AAV vectors. Annu. Rev. Genet. 2004, 38, 819-845.
-
(2004)
Annu. Rev. Genet
, vol.38
, pp. 819-845
-
-
McCarty, D.M.1
Young Jr., S.M.2
Samulski, R.J.3
-
5
-
-
71549132206
-
Adeno-associated viral vectors and their redirection to cell-type specific receptors
-
Michelfelder, S.; Trepel, M. Adeno-associated viral vectors and their redirection to cell-type specific receptors. Adv. Genet. 2009, 67, 29-60.
-
(2009)
Genet
, vol.67
, pp. 29-60
-
-
Michelfelder, S.1
Trepel, M.2
-
6
-
-
0036726577
-
Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy
-
Nicklin, S.A.; Baker, A.H. Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy. Curr. Gene Ther. 2002, 2, 273-293.
-
(2002)
Curr. Gene Ther
, vol.2
, pp. 273-293
-
-
Nicklin, S.A.1
Baker, A.H.2
-
7
-
-
33746874152
-
Adeno-associated virus serotypes: Vector toolkit for human gene therapy
-
Wu, Z.; Asokan, A.; Samulski, R.J. Adeno-associated virus serotypes: Vector toolkit for human gene therapy. Mol. Ther. 2006, 14, 316-327.
-
(2006)
Mol. Ther
, vol.14
, pp. 316-327
-
-
Wu, Z.1
Asokan, A.2
Samulski, R.J.3
-
8
-
-
0032870158
-
Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2
-
Girod, A.; Ried, M.; Wobus, C.; Lahm, H.; Leike, K.; Kleinschmidt, J.; Deleage, G.; Hallek, M. Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2. Nat. Med. 1999, 5, 1052-1056.
-
(1999)
Nat. Med
, vol.5
, pp. 1052-1056
-
-
Girod, A.1
Ried, M.2
Wobus, C.3
Lahm, H.4
Leike, K.5
Kleinschmidt, J.6
Deleage, G.7
Hallek, M.8
-
9
-
-
0034963928
-
Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids
-
Grifman, M.; Trepel, M.; Speece, P.; Gilbert, L.B.; Arap, W.; Pasqualini, R.; Weitzman, M.D. Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids. Mol. Ther. 2001, 3, 964-975.
-
(2001)
Mol. Ther
, vol.3
, pp. 964-975
-
-
Grifman, M.1
Trepel, M.2
Speece, P.3
Gilbert, L.B.4
Arap, W.5
Pasqualini, R.6
Weitzman, M.D.7
-
10
-
-
0038027345
-
RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism
-
Shi, W.; Bartlett, J.S. RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism. Mol. Ther. 2003, 7, 515-525.
-
(2003)
Mol. Ther
, vol.7
, pp. 515-525
-
-
Shi, W.1
Bartlett, J.S.2
-
11
-
-
0033007934
-
Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody
-
Bartlett, J.S.; Kleinschmidt, J.; Boucher, R.C.; Samulski, R.J. Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody. Nat. Biotechnol. 1999, 17, 181-186.
-
(1999)
Nat. Biotechnol
, vol.17
, pp. 181-186
-
-
Bartlett, J.S.1
Kleinschmidt, J.2
Boucher, R.C.3
Samulski, R.J.4
-
12
-
-
0036893196
-
Conjugate-based targeting of recombinant adeno-associated virus type 2 vectors by using avidin-linked ligands
-
Ponnazhagan, S.; Mahendra, G.; Kumar, S.; Thompson, J.A.; Castillas, M., Jr. Conjugate-based targeting of recombinant adeno-associated virus type 2 vectors by using avidin-linked ligands. J. Virol. 2002, 76, 12900-12907.
-
(2002)
J. Virol
, vol.76
, pp. 12900-12907
-
-
Ponnazhagan, S.1
Mahendra, G.2
Kumar, S.3
Thompson, J.A.4
Castillas Jr, M.5
-
13
-
-
0034692421
-
Molecular adaptors for vascular-targeted adenoviral gene delivery
-
Trepel, M.G., Weitzman, M.D.; Pasqualini, R. Molecular adaptors for vascular-targeted adenoviral gene delivery. Hum. Gene Ther. 2000, 11, 1971-1981.
-
(2000)
Hum. Gene Ther
, vol.11
, pp. 1971-1981
-
-
Trepel, M.G.1
Weitzman, M.D.2
Pasqualini, R.3
-
14
-
-
0042360384
-
Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors
-
Müller, O.J.; Kaul, F.; Weitzman, M.D.; Pasqualini, R.; Arap, W.; Kleinschmidt, J.A.; Trepel, M. Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors. Nat. Biotechnol. 2003, 21, 1040-1046.
-
(2003)
Nat. Biotechnol
, vol.21
, pp. 1040-1046
-
-
Müller, O.J.1
Kaul, F.2
Weitzman, M.D.3
Pasqualini, R.4
Arap, W.5
Kleinschmidt, J.A.6
Trepel, M.7
-
15
-
-
33751256855
-
Isolation of targeted AAV2 vectors from novel virus display libraries
-
Waterkamp, D.A.; Muller, O.J.; Ying, Y.; Trepel, M.; Kleinschmidt, J.A. Isolation of targeted AAV2 vectors from novel virus display libraries. J. Gene Med. 2006, 8, 1307-1319.
-
(2006)
J. Gene Med
, vol.8
, pp. 1307-1319
-
-
Waterkamp, D.A.1
Muller, O.J.2
Ying, Y.3
Trepel, M.4
Kleinschmidt, J.A.5
-
16
-
-
36148986778
-
Vectors selected from adeno-associated viral display peptide libraries for leukemia cell-targeted cytotoxic gene therapy
-
Michelfelder, S.; Lee, M.K.; deLima-Hahn, E.; Wilmes, T.; Kaul, F.; Muller, O.; Kleinschmidt, J.A.; Trepel, M. Vectors selected from adeno-associated viral display peptide libraries for leukemia cell-targeted cytotoxic gene therapy. Exp. Hematol. 2007, 35, 1766-1776.
-
(2007)
Exp. Hematol
, vol.35
, pp. 1766-1776
-
-
Michelfelder, S.1
Lee, M.K.2
Delima-Hahn, E.3
Wilmes, T.4
Kaul, F.5
Muller, O.6
Kleinschmidt, J.A.7
Trepel, M.8
-
17
-
-
65249116937
-
Successful expansion but not complete restriction of tropism of adeno-associated virus by in vivo biopanning of random virus display peptide libraries
-
Michelfelder, S.; Kohlschutter, J.; Skorupa, A.; Pfennings, S.; Muller, O.; Kleinschmidt, J.A.; Trepel, M. Successful expansion but not complete restriction of tropism of adeno-associated virus by in vivo biopanning of random virus display peptide libraries. PLoS One 2009, 4, e5122.
-
(2009)
PLoS One
, vol.4
-
-
Michelfelder, S.1
Kohlschutter, J.2
Skorupa, A.3
Pfennings, S.4
Muller, O.5
Kleinschmidt, J.A.6
Trepel, M.7
-
18
-
-
77955654722
-
Heart-targeted adeno-associated viral vectors selected by in vivo biopanning of a random viral display peptide library
-
Ying, Y.; Muller, O.J.; Goehringer, C.; Leuchs, B.; Trepel, M.; Katus, H.A.; Kleinschmidt, J.A. Heart-targeted adeno-associated viral vectors selected by in vivo biopanning of a random viral display peptide library. Gene Ther. 2010, 17, 980-990.
-
(2010)
Gene Ther
, vol.17
, pp. 980-990
-
-
Ying, Y.1
Muller, O.J.2
Goehringer, C.3
Leuchs, B.4
Trepel, M.5
Katus, H.A.6
Kleinschmidt, J.A.7
-
19
-
-
27744497012
-
Adeno-associated virus vectors: Potential applications for cancer gene therapy
-
Li, C.; Bowles, D.E.; van Dyke, T.; Samulski, R.J. Adeno-associated virus vectors: Potential applications for cancer gene therapy. Canc. Gene Ther. 2005, 12, 913-925.
-
(2005)
Canc. Gene Ther
, vol.12
, pp. 913-925
-
-
Li, C.1
Bowles, D.E.2
van Dyke, T.3
Samulski, R.J.4
-
20
-
-
0029921190
-
Selective killing of AFP-positive hepatocellular carcinoma cells by adeno-associated virus transfer of the herpes simplex virus thymidine kinase gene
-
Su, H.; Chang, J.C.; Xu, S.M.; Kan, Y.W. Selective killing of AFP-positive hepatocellular carcinoma cells by adeno-associated virus transfer of the herpes simplex virus thymidine kinase gene. Hum. Gene Ther. 1996, 7, 463-470.
-
(1996)
Hum. Gene Ther
, vol.7
, pp. 463-470
-
-
Su, H.1
Chang, J.C.2
Xu, S.M.3
Kan, Y.W.4
-
21
-
-
33646034578
-
A hybrid vector for ligand-directed tumor targeting and molecular imaging
-
Hajitou, A.; Trepel, M.; Lilley, C.E.; Soghomonyan, S.; Alauddin, M.M.; Marini, F.C., 3rd; Restel, B.H.; Ozawa, M.G.; Moya, C.A.; Rangel, R.; Sun, Y.; Zaoui, K.; Schmidt, M.; von Kalle, C.; Weitzman, M.D.; Gelovani, J.G.; Pasqualini, R.; Arap, W. A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell 2006, 125, 385-398.
-
(2006)
Cell
, vol.125
, pp. 385-398
-
-
Hajitou, A.1
Trepel, M.2
Lilley, C.E.3
Soghomonyan, S.4
Alauddin, M.M.5
Marini III, F.C.6
Restel, B.H.7
Ozawa, M.G.8
Moya, C.A.9
Rangel, R.10
Sun, Y.11
Zaoui, K.12
Schmidt, M.13
von Kalle, C.14
Weitzman, M.D.15
Gelovani, J.G.16
Pasqualini, R.17
Arap, W.18
-
22
-
-
68849090740
-
A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer
-
Trepel, M.; Stoneham, C.A.; Eleftherohorinou, H.; Mazarakis, N.D.; Pasqualini, R.; Arap, W.; Hajitou, A. A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer. Mol. Canc. Ther. 2009, 8, 2383-2391.
-
(2009)
Mol. Canc Ther
, vol.8
, pp. 2383-2391
-
-
Trepel, M.1
Stoneham, C.A.2
Eleftherohorinou, H.3
Mazarakis, N.D.4
Pasqualini, R.5
Arap, W.6
Hajitou, A.7
-
23
-
-
44449139974
-
Potent antitumor effect of TRAIL mediated by a novel adeno-associated viral vector targeting to telomerase activity for human hepatocellular carcinoma
-
Wang, Y.; Huang, F.; Cai, H.; Zhong, S.; Liu, X.; Tan, W.S. Potent antitumor effect of TRAIL mediated by a novel adeno-associated viral vector targeting to telomerase activity for human hepatocellular carcinoma. J. Gene Med. 2008, 10, 518-526.
-
(2008)
J. Gene Med
, vol.10
, pp. 518-526
-
-
Wang, Y.1
Huang, F.2
Cai, H.3
Zhong, S.4
Liu, X.5
Tan, W.S.6
-
24
-
-
44149084623
-
AAV-mediated TRAIL gene expression driven by hTERT promoter suppressed human hepatocellular carcinoma growth in mice
-
Zhang, Y.; Ma, H.; Zhang, J.; Liu, S.; Liu, Y.; Zheng, D. AAV-mediated TRAIL gene expression driven by hTERT promoter suppressed human hepatocellular carcinoma growth in mice. Life Sci. 2008, 82, 1154-1161.
-
(2008)
Life Sci
, vol.82
, pp. 1154-1161
-
-
Zhang, Y.1
Ma, H.2
Zhang, J.3
Liu, S.4
Liu, Y.5
Zheng, D.6
-
25
-
-
0032445097
-
A strategy for enhancing the transcriptional activity of weak cell type-specific promoters
-
Nettelbeck, D.M.; Jerome, V.; Muller, R. A strategy for enhancing the transcriptional activity of weak cell type-specific promoters. Gene Ther. 1998, 5, 1656-1664.
-
(1998)
Gene Ther
, vol.5
, pp. 1656-1664
-
-
Nettelbeck, D.M.1
Jerome, V.2
Muller, R.3
-
26
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen, M.; Bujard, H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 1992, 89, 5547-5551.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
27
-
-
0026552246
-
The crystal structure of diphtheria toxin
-
Choe, S.; Bennett, M.J.; Fujii, G.; Curmi, P.M.; Kantardjieff, K.A.; Collier, R.J.; Eisenberg, D. The crystal structure of diphtheria toxin. Nature 1992, 357, 216-222.
-
(1992)
Nature
, vol.357
, pp. 216-222
-
-
Choe, S.1
Bennett, M.J.2
Fujii, G.3
Curmi, P.M.4
Kantardjieff, K.A.5
Collier, R.J.6
Eisenberg, D.7
-
28
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
Nakano, K.; Vousden, K.H. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell. 2001, 7, 683-694.
-
(2001)
Mol. Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
29
-
-
0026587657
-
Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease
-
Guy, C.T.; Cardiff, R.D.; Muller, W.J. Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol. Cell. Biol. 1992, 12, 954-961.
-
(1992)
Mol. Cell. Biol
, vol.12
, pp. 954-961
-
-
Guy, C.T.1
Cardiff, R.D.2
Muller, W.J.3
-
30
-
-
0032773889
-
Titration of AAV-2 particles via a novel capsid ELISA: Packaging of genomes can limit production of recombinant AAV-2
-
Grimm, D.; Kern, A.; Pawlita, M.; Ferrari, F.; Samulski, R.; Kleinschmidt, J. Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2. Gene Ther. 1999, 6, 1322-1330.
-
(1999)
Gene Ther
, vol.6
, pp. 1322-1330
-
-
Grimm, D.1
Kern, A.2
Pawlita, M.3
Ferrari, F.4
Samulski, R.5
Kleinschmidt, J.6
-
31
-
-
0036209722
-
Cell-specific Cre-mediated activation of the diphtheria toxin gene in pituitary tumor cells: Potential for cytotoxic gene therapy
-
Lee, E.J.; Jameson, J.L. Cell-specific Cre-mediated activation of the diphtheria toxin gene in pituitary tumor cells: Potential for cytotoxic gene therapy. Hum. Gene Ther. 2002, 13, 533-542.
-
(2002)
Hum. Gene Ther
, vol.13
, pp. 533-542
-
-
Lee, E.J.1
Jameson, J.L.2
-
32
-
-
2642642141
-
Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
-
Xiao, X.; Li, J.; Samulski, R.J. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J. Virol. 1998, 72, 2224-2232.
-
(1998)
J. Virol
, vol.72
, pp. 2224-2232
-
-
Xiao, X.1
Li, J.2
Samulski, R.J.3
-
33
-
-
2442737801
-
Purification of recombinant adeno-associated virus by iodixanol gradient ultracentrifugation allows rapid and reproducible preparation of vector stocks for gene transfer in the nervous system
-
Hermens, W.T.; ter Brake, O.; Dijkhuizen, P.A.; Sonnemans, M.A.; Grimm, D.; Kleinschmidt, J.A.; Verhaagen, J. Purification of recombinant adeno-associated virus by iodixanol gradient ultracentrifugation allows rapid and reproducible preparation of vector stocks for gene transfer in the nervous system. Hum. Gene Ther. 1999, 10, 1885-1891.
-
(1999)
Hum. Gene Ther
, vol.10
, pp. 1885-1891
-
-
Hermens, W.T.1
Ter, B.O.2
Dijkhuizen, P.A.3
Sonnemans, M.A.4
Grimm, D.5
Kleinschmidt, J.A.6
Verhaagen, J.7
-
34
-
-
50549158051
-
Studies on succinate-tetrazolium reductase systems. Iii. Points of coupling of four different tetrazolium salts
-
Slater, T.F.; Sawyer, B.; Straeuli, U. Studies on Succinate-Tetrazolium Reductase Systems. Iii. Points of Coupling of Four Different Tetrazolium Salts. Biochim. Biophys. Acta 1963, 77, 383-393.
-
(1963)
Biochim. Biophys. Acta
, vol.77
, pp. 383-393
-
-
Slater, T.F.1
Sawyer, B.2
Straeuli, U.3
-
35
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Method. 1983, 65, 55-63.
-
(1983)
J. Immunol. Method
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
36
-
-
33646415691
-
Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs
-
Wang, H.; Qian, H.; Yu, J.; Zhang, X.; Zhang, L.; Fu, M.; Liang, X.; Zhan, Q.; Lin, C. Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs. Canc. Biol. Ther. 2006, 5, 380-385.
-
(2006)
Canc. Biol. Ther
, vol.5
, pp. 380-385
-
-
Wang, H.1
Qian, H.2
Yu, J.3
Zhang, X.4
Zhang, L.5
Fu, M.6
Liang, X.7
Zhan, Q.8
Lin, C.9
-
37
-
-
33646741204
-
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
-
Yu, J.; Yue, W.; Wu, B.; Zhang, L. PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation. Clin. Canc. Res. 2006, 12, 2928-2936.
-
(2006)
Clin. Canc. Res
, vol.12
, pp. 2928-2936
-
-
Yu, J.1
Yue, W.2
Wu, B.3
Zhang, L.4
-
38
-
-
0027483695
-
The bystander effect: Tumor regression when a fraction of the tumor mass is genetically modified
-
Freeman, S.M.; Abboud, C.N.; Whartenby, K.A.; Packman, C.H.; Koeplin, D.S.; Moolten, F.L.; Abraham, G.N. The bystander effect: Tumor regression when a fraction of the tumor mass is genetically modified. Canc. Res. 1993, 53, 5274-5283.
-
(1993)
Canc. Res
, vol.53
, pp. 5274-5283
-
-
Freeman, S.M.1
Abboud, C.N.2
Whartenby, K.A.3
Packman, C.H.4
Koeplin, D.S.5
Moolten, F.L.6
Abraham, G.N.7
-
39
-
-
0031446784
-
Regulated expression of the diphtheria toxin A chain by a tumor-specific chimeric transcription factor results in selective toxicity for alveolar rhabdomyosarcoma cells
-
Massuda, E.S.; Dunphy, E.J.; Redman, R.A.; Schreiber, J.J.; Nauta, L.E.; Barr, F.G.; Maxwell, I.H.; Cripe, T.P. Regulated expression of the diphtheria toxin A chain by a tumor-specific chimeric transcription factor results in selective toxicity for alveolar rhabdomyosarcoma cells. Proc. Natl. Acad. Sci. USA 1997, 94, 14701-14706.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14701-14706
-
-
Massuda, E.S.1
Dunphy, E.J.2
Redman, R.A.3
Schreiber, J.J.4
Nauta, L.E.5
Barr, F.G.6
Maxwell, I.H.7
Cripe, T.P.8
-
40
-
-
0018167496
-
One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell
-
Yamaizumi, M.M., E.; Uchida, T.; Okada, Y. One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell. Cell 1978, 15, 245-250.
-
(1978)
Cell
, vol.15
, pp. 245-250
-
-
Yamaizumi, M.M.E.1
Uchida, T.2
Okada, Y.3
|