Variation in Lymph Node Assessment After Colon Cancer Resection: Patient, Surgeon, Pathologist, or Hospital?

Journal of Gastrointestinal Surgery

Volumn 15, Issue 3, 2011, Pages 471-479

  Nathan, Hari ^a   Shore, Andrew D ^a   Anders, Robert A ^a   Wick, Elizabeth C ^a   Gearhart, Susan L ^a   Pawlik, Timothy M ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Colon cancer; Lymph node; Outcomes; Quality; Staging

Indexed keywords

AGED; ARTICLE; CANCER REGISTRY; CANCER STAGING; COLON RESECTION; COLON TUMOR; FEMALE; HOSPITAL; HUMAN; LYMPH NODE; LYMPH NODE METASTASIS; MALE; PATHOLOGY; PHYSICIAN; PRACTICE GUIDELINE; QUALITY CONTROL; STATISTICAL MODEL; STATISTICS;

AGED; AGED, 80 AND OVER; BENCHMARKING; COLECTOMY; COLONIC NEOPLASMS; FEMALE; GUIDELINE ADHERENCE; HOSPITALS; HUMANS; LOGISTIC MODELS; LYMPH NODES; LYMPHATIC METASTASIS; MALE; NEOPLASM STAGING; PHYSICIANS; PRACTICE GUIDELINES AS TOPIC; SEER PROGRAM;

EID: 79952073194     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11605-010-1410-9     Document Type: Article

References (38)

1. Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA: a cancer journal for clinicians 2010; 60: 277-300.
2. Sargent D, Sobrero A, Grothey A, et al. Evidence for cure by adjuvant therapy in colon cancer: observations based on individual patient data from 20, 898 patients on 18 randomized trials. J Clin Oncol 2009; 27: 872-7.
3. Chen SL, Bilchik AJ. More extensive nodal dissection improves survival for stages I to III of colon cancer: a population-based study. Annals of surgery 2006; 244: 602-10.
4. Le Voyer TE, Sigurdson ER, Hanlon AL, et al. Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol 2003; 21: 2912-9.
5. Swanson RS, Compton CC, Stewart AK, Bland KI. The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined. Annals of surgical oncology 2003; 10: 65-71.
6. Bui L, Rempel E, Reeson D, Simunovic M. Lymph node counts, rates of positive lymph nodes, and patient survival for colon cancer surgery in Ontario, Canada: a population-based study. Journal of surgical oncology 2006; 93: 439-45.
7. National Quality Forum: National voluntary consensus standards for quality of cancer care: a consensus report. (Accessed at http://www. qualityforum. org/pdf/reports/Cancer_Nonmember_Report. pdf.).
8. Baxter NN, Virnig DJ, Rothenberger DA, Morris AM, Jessurun J, Virnig BA. Lymph node evaluation in colorectal cancer patients: a population-based study. Journal of the National Cancer Institute 2005; 97: 219-25.
9. Wright FC, Law CH, Berry S, Smith AJ. Clinically important aspects of lymph node assessment in colon cancer. J Surg Oncol 2009; 99: 248-55.
10. Tekkis PP, Smith JJ, Heriot AG, Darzi AW, Thompson MR, Stamatakis JD. A national study on lymph node retrieval in resectional surgery for colorectal cancer. Dis Colon Rectum 2006; 49: 1673-83.
11. Bilimoria KY, Stewart AK, Palis BE, Bentrem DJ, Talamonti MS, Ko CY. Adequacy and importance of lymph node evaluation for colon cancer in the elderly. Journal of the American College of Surgeons 2008; 206: 247-54.
12. Etzioni D, Spencer M. Nodal harvest: surgeon or pathologist? Dis Colon Rectum 2008; 51: 366-7; author reply 8.
13. Wang J, Kulaylat M, Rockette H, et al. Should total number of lymph nodes be used as a quality of care measure for stage III colon cancer? Ann Surg 2009; 249: 559-63.
14. Warren JL, Klabunde CN, Schrag D, Bach PB, Riley GF. Overview of the SEER-Medicare data: content, research applications, and generalizability to the United States elderly population. Med Care 2002; 40: IV-3-18.
15. Nathan H, Pawlik TM. Limitations of claims and registry data in surgical oncology research. Ann Surg Oncol 2008; 15: 415-23.
16. Birkmeyer JD, Siewers AE, Finlayson EV, et al. Hospital volume and surgical mortality in the United States. The New England journal of medicine 2002; 346: 1128-37.
17. Schrag D, Bach PB, Dahlman C, Warren JL. Identifying and measuring hospital characteristics using the SEER-Medicare data and other claims-based sources. Medical care 2002; 40: IV-96-103.
18. Hollenbeck BK, Hong J, Zaojun Y, Birkmeyer JD. Misclassification of hospital volume with Surveillance, Epidemiology, and End Results Medicare data. Surg Innov 2007; 14: 192-8.
19. Rabe-Hesketh S, Skrondal A. Multilevel and longitudinal modeling using STATA (ed 2). College Station: STATA; 2008.
20. Larsen K, Merlo J. Appropriate assessment of neighborhood effects on individual health: integrating random and fixed effects in multilevel logistic regression. Am J Epidemiol 2005; 161: 81-8.
21. Wong SL, Ji H, Hollenbeck BK, Morris AM, Baser O, Birkmeyer JD. Hospital lymph node examination rates and survival after resection for colon cancer. Jama 2007; 298: 2149-54.
22. Baxter NN. Is lymph node count an ideal quality indicator for cancer care? J Surg Oncol 2009; 99: 265-8.
23. Johnson PM, Porter GA, Ricciardi R, Baxter NN. Increasing negative lymph node count is independently associated with improved long-term survival in stage IIIB and IIIC colon cancer. J Clin Oncol 2006; 24: 3570-5.
24. Galon J, Costes A, Sanchez-Cabo F, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006; 313: 1960-4.
25. Pages F, Berger A, Camus M, et al. Effector memory T cells, early metastasis, and survival in colorectal cancer. N Engl J Med 2005; 353: 2654-66.
26. Rieger NA, Barnett FS, Moore JW, et al. Quality of pathology reporting impacts on lymph node yield in colon cancer. J Clin Oncol 2007; 25: 463; author reply-4.
27. Ostadi MA, Harnish JL, Stegienko S, Urbach DR. Factors affecting the number of lymph nodes retrieved in colorectal cancer specimens. Surg Endosc 2007; 21: 2142-6.
28. Johnson PM, Malatjalian D, Porter GA. Adequacy of nodal harvest in colorectal cancer: a consecutive cohort study. J Gastrointest Surg 2002; 6: 883-88; discussion 9-90.
29. Evans MD, Barton K, Rees A, Stamatakis JD, Karandikar SS. The impact of surgeon and pathologist on lymph node retrieval in colorectal cancer and its impact on survival for patients with Dukes' stage B disease. Colorectal Dis 2008; 10: 157-64.
30. Lemmens VE, van Lijnschoten I, Janssen-Heijnen ML, Rutten HJ, Verheij CD, Coebergh JW. Pathology practice patterns affect lymph node evaluation and outcome of colon cancer: a population-based study. Ann Oncol 2006; 17: 1803-9.
31. Pheby DF, Levine DF, Pitcher RW, Shepherd NA. Lymph node harvests directly influence the staging of colorectal cancer: evidence from a regional audit. J Clin Pathol 2004; 57: 43-7.
32. Donabedian A. The quality of care. How can it be assessed? Jama 1988; 260: 1743-8.
33. Bull AD, Biffin AH, Mella J, et al. Colorectal cancer pathology reporting: a regional audit. J Clin Pathol 1997; 50: 138-42.
34. Miller EA, Woosley J, Martin CF, Sandler RS. Hospital-to-hospital variation in lymph node detection after colorectal resection. Cancer 2004; 101: 1065-71.
35. Morris EJ, Maughan NJ, Forman D, Quirke P. Identifying stage III colorectal cancer patients: the influence of the patient, surgeon, and pathologist. J Clin Oncol 2007; 25: 2573-9.
36. Kelder W, Inberg B, Plukker JT, Groen H, Baas PC, Tiebosch AT. Effect of modified Davidson's fixative on examined number of lymph nodes and TNM-stage in colon carcinoma. Eur J Surg Oncol 2008; 34: 525-30.
37. Bilimoria KY, Bentrem DJ, Stewart AK, et al. Lymph node evaluation as a colon cancer quality measure: a national hospital report card. J Natl Cancer Inst 2008; 100: 1310-7.
38. Clinical Outcomes of Surgical Therapy Study Group. A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med 2004; 350(20): 2050-9.