Case 6-2011: A 77-year-old man with dyspnea, weakness, and diaphoresis

New England Journal of Medicine

Volumn 364, Issue 8, 2011, Pages 759-767

  Tsibris, Athe M N ^a,b   Shepard, Jo Anne O ^a,b   Zukerberg, Lawrence R ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFEPIME; METRONIDAZOLE; VANCOMYCIN;

ABDOMINAL INFECTION; AGED; ANAPLASMA PHAGOCYTOPHILUM; ARTICLE; ATELECTASIS; BLOOD SMEAR; CARDIOMEGALY; CASE REPORT; DIAPHORESIS; DIFFERENTIAL DIAGNOSIS; DYSPNEA; ECG ABNORMALITY; HEART ATRIUM FIBRILLATION; HUMAN; HUMAN GRANULOCYTIC ANAPLASMOSIS; LABORATORY TEST; MALE; PLEURA EFFUSION; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SEPSIS; THORAX RADIOGRAPHY; WEAKNESS; ANAPLASMOSIS; ASTHENIA; BACTERIAL PNEUMONIA; BLOOD; CARDIOMYOPATHY; CLINICAL OBSERVATION; CLINICAL STUDY; DIAGNOSIS; FATALITY; INFECTION; ISOLATION AND PURIFICATION; MICROBIOLOGY; NEUTROPHIL; SWEATING;

AGED; ANAPLASMA PHAGOCYTOPHILUM; ANAPLASMOSIS; ASTHENIA; CARDIOMYOPATHIES; DIAGNOSIS, DIFFERENTIAL; DYSPNEA; FATAL OUTCOME; HUMANS; INFECTION; MALE; NEUTROPHILS; PNEUMONIA, BACTERIAL; SWEATING;

EID: 79952035062     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcpc1011320     Document Type: Article

References (20)

1. Panda A, Arjona A, Sapey E, et al. Human innate immunosenescence: causes and consequences for immunity in old age. Trends Immunol 2009;30:325-33.
2. Shanley DP, Aw D, Manley NR, Palmer DB. An evolutionary perspective on the mechanisms of immunosenescence. Trends Immunol 2009;30:374-81.
3. Marston BJ, Plouffe JF, File TM Jr, et al. Incidence of community-acquired pneumonia requiring hospitalization: results of a population-based active surveillance study in Ohio. Arch Intern Med 1997;157:1709-18. (Pubitemid 27327407)
4. Case Records of the Massachusetts General Hospital (Case 29-2009). N Engl J Med 2009;361:1189-98.
5. Health, United States, 2008: with special feature on the health of young adults. Hyattsville, MD: National Center for Health Statistics. (http://www.cdc.gov/nchs/data/hus/hus08.pdf.)
6. Baddour LM, Wilson WR, Bayer AS, et al. Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America. Circulation 2005;111(23):e394-434. [Errata, Circulation 2005;112:2373, 2007;115(15): e408, 116(21):e547, 2008;118(12):e497.]
7. Lew JF, Glass RI, Gangarosa RE, Cohen IP, Bern C, Moe CL. Diarrheal deaths in the United States, 1979 through 1987: a special problem for the elderly. JAMA 1991;265:3280-4.
8. Zilberberg MD, Shorr AF, Kollef MH. Increase in adult Clostridium difficile-related hospitalizations and case-fatality rate, United States, 2000-2005. Emerg Infect Dis 2008;14:929-31.
9. Biedenbach DJ, Moet GJ, Jones RN. Occurrence and antimicrobial resistance pattern comparisons among bloodstream infection isolates from the SENTRY Antimicrobial Surveillance Program (1997-2002). Diagn Microbiol Infect Dis 2004;50:59-69.
10. Rocky Mountain spotted fever - statistics. Atlanta: Centers for Disease Control and Prevention. (http://www.cdc.gov/ticks/diseases/rocky-mountain- spotted-fever/statistics.html.)
11. Sexton DJ, Corey GR. Rocky Mountain "spotless" and "almost spotless" fever: a wolf in sheep's clothing. Clin Infect Dis 1992;15:439-48.
12. Bakken JS, Dumler JS, Chen SM, Eckman MR, Van Etta LL, Walker DH. Human granulocytic ehrlichiosis in the upper Midwest United States: a new species emerging? JAMA 1994;272:212-8.
13. Bakken JS, Dumler S. Human granulocytic anaplasmosis. Infect Dis Clin North Am 2008;22:433-48.
14. Dumler JS, Choi KS, Garcia-Garcia JC, et al. Human granulocytic anaplasmosis and Anaplasma phagocytophilum. Emerg Infect Dis 2005;11:1828-34. (Pubitemid 43361465)
15. Anaplasmosis - statistics. Atlanta: Centers for Disease Control and Prevention. (http://www.cdc.gov/ticks/diseases/anaplasmosis/statistics.html.)
16. Ehrlichiosis - statistics. Atlanta: Centers for Disease Control and Prevention. (http://www.cdc.gov/ticks/diseases/ehrlichiosis/statistics.html.)
17. Anaplasmosis HG (HGA) surveillance in Massachusetts. Boston: Massachusetts Department of Public Health, 2008.
18. Holman MS, Caporale DA, Goldberg J, et al. Anaplasma phagocytophilum, Babesia microti, and Borrelia burgdorferi in Ixodes scapularis, southern coastal Maine. Emerg Infect Dis 2004;10:744-6. (Pubitemid 38425479)
19. Bakken JS, Krueth JK, Lund T, Malkovitch D, Asanovich K, Dumler JS. Exposure to deer blood may be a cause of human granulocytic ehrlichiosis. Clin Infect Dis 1996;23:198. (Pubitemid 26323830)
20. Horowitz HW, Kilchevsky E, Haber S, et al. Perinatal transmission of the agent of human granulocytic ehrlichiosis. N Engl J Med 1998;339:375-8. (Pubitemid 28363800)