The cellular expression of GABAA receptor α1 subunit during spermatogenesis in the mouse testis

Histology and Histopathology

Volumn 25, Issue 10, 2010, Pages 1229-1238

  Kanbara, Kiyoto ^a   Okamoto, Keiko ^b   Nomura, Sakashi ^c   Kaneko, Takeshi ^b   Watanabe, Masahito ^d   Otsuki, Yoshinori ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c BUKKYO UNIVERSITY   (Japan)

^d OSAKA HEALTH SCIENCE UNIVERSITY   (Japan)

Author keywords

Electron microscopy; GABAergic system; Male reproductive system; Polymerase chain reaction

Indexed keywords

MUS;

4 AMINOBUTYRIC ACID A RECEPTOR; GABRA1 PROTEIN, MOUSE; MESSENGER RNA;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CELL NUCLEUS; CHEMISTRY; CONFOCAL MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MOUSE; PROTEIN TERTIARY STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPERMATOGENESIS; SPERMATOZOON; TESTIS; ULTRASTRUCTURE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; MICROSCOPY, IMMUNOELECTRON; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, GABA-A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPERMATOGENESIS; SPERMATOZOA; TESTIS;

EID: 79952032987     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Abe H., Yanagawa Y., Kanbara K., Maemura K., Hayasaki H., Azuma H., Katsuoka Y., Yabumoto M. and Watanabe M. (2005). Epithelial localization of green fluorescent protein-positive cells in epididymis of the GAD67-GFP knock-in mouse. J. Androl. 26, 568-577.
2. A receptor subunits in peripheral tissues. Neurosci. Res. 35, 145-153.
3. A receptor regulation of stem cell proliferation. Nature Lett.451, 460-464.
4. Barnard E.A., Skolnick P., Olsen R.W., Mohler H., Sieghart W., Biggio G., Braestrup C., Bateson A.N. and Langer S.Z. (1998). International union of pharmacology. XV. Subtypes of g-aminobutyric acidA receptors: Classification on the basis of subunit structure and receptor function. Pharmacol. Rev. 50, 291-313.
5. Calogero A.E., Hall J., Fishel S., Green S., Hunter A. and D'Agata R. (1996). Effects of gamma-aminobutyric acid on human sperm motility and hyperactivation. Mol. Hum. Reprod. 2, 733-738.
6. A-receptor diversity emerges a unified vision of GABAergic inhibition. Annu. Rev. Pharmacol. Toxicol. 38, 321-350.
7. de las Heras M.A., Valcarcel A. and Perez L.J. (1997). In vitro capacitating effect of gamma-aminobutyric acid in ram spermatozoa. Biol. Reprod. 56, 964-968.
8. Fiszman M.L. and Schousboe A. (2004). Role calcium and kinase on the neurotrophic effect induced by GABA. J. Neurosci. Res. 76, 435-441.
9. Hayasaki H., Sohma Y., Kanbara K., Maemura K., Kubota T. and Watanabe M. (2006). A local GABAergic system within rat trigeminal ganglion cells. Eur. J. Neurosci. 23, 1-13.
10. Honda S. and Hirose S. (2003). Stage-specific enhanced expression of mitochondrial fusion and fission factors during spermatogenesis in rat testis. Biochem. Biophys. Res. Commun. 311, 424-432.
11. B receptor subunit proteins during spermatogenesis in rat testis. J. Androl. 26, 485-493.
12. Kawamata M. and Nishimori K. (2006). Mice deficient in Dmrt7 show infertility with spermatogenic arrest at pachytene stage. FEBS Lett. 580, 6442-6446.
13. Kim S., Bardwell V.J. and Zarkower D. (2007). Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation. Dev. Biol. 307, 314-327.
14. B receptors in Schwann cells influence proliferation and myelin protein expression. Eur. J. Neurosci. 19, 2641-2649.
15. A-receptor subtypes really occur in the brain? Trends Neurosci. 19, 139-143.
16. McCarrey J.R., Geyer C.B. and Yoshioka H. (2005). Epigenetic regulation of testis-specific gene expression. Ann. NY Acad. Sci. 1061, 226-242.
17. A receptors. Brain Res. Rev. 29, 196-217.
18. Meizel S. (1997). Amino Acid neurotransmitter receptor/ chloride channels of mammalian sperm and the acrosome reaction. Biol. Reprod. 56, 569-574.
19. Murphy M.W., Zarkower D. and Bardwell V.J. (2007). Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA. BMC Mol. Biol. 8, 1-14.
20. Raymond C.S., Murphy M.W., O'Sullivan M.G., Bardwell V.J. and Zarkower D. (2007). Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation. Genes Dev. 16, 2587-2595.
21. Shaha C. (2007). Modulators of spermatogenic cell survival. Soc. Reprod. Fertil. Suppl. 63, 173-86.
22. Shi Q.X., Yuan Y.Y. and Roldan E.R. (1997). γ-Aminobutyric acid (GABA) induces the acrosome reaction in human spermatozoa. Mol. Hum. Reprod. 3, 677-683.
23. B receptors in rat growth plate chondrocytes: Activation of the GABA receptors promotes proliferation of mouse chondrogenic ATDC5 cells. Mol. Cell Biochem. 273, 117-126.
24. Tillakaratne N.J.K., Medina-Kauwe L. and Gibson K.M. (1995). Gammaaminobutyric acid (GABA) metabolism in mammalian neural and nonneural tissues. Comp. Biochem. Physiol. 112A, 247-263.
25. A receptor is repressed by c-myc and is pro-apoptotic. J. Cell Biochem. 97, 1094-1103.
26. Wang J.M., Johnston P.B., Ball B.G. and Brinton R.D. (2005). The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression. J. Neurosci. 25, 4706-4718.
27. Watanabe M., Maemura K., Kanbara K., Tamayama T. and Hayasaki H. (2002). GABA and GABA receptors in the central nervous system and other organs. Int. Rev. Cytol. 213, 1-47.
28. Xiouri M and Papazafiri P. (2006). Anti-apoptotic effects of allopregnanolone on P19 neurons. Eur. J. Neurosci. 23, 43-54.
29. Zheng J., Xia X., Ding H., Yan A., Hu S., Gong X., Zong S., Zhang Y. and Shengg H.Z. (2008). Erasure of the paternal transcription program during spermiogenesis: The first in the reprogramming of sperm chromatin for zygotic development. Dev. Dyn. 237, 1463-1476.