Radical-scavenging activity of melatonin, either alone or in combination with vitamin E, ascorbate or 2-mercaptoethanol as co-antioxidants, using the induction period method

In Vivo

Volumn 25, Issue 1, 2011, Pages 49-53

  Kadoma, Yoshinori ^a   Fujisawa, Seiichiro ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

Ascorbate; Induction period method; Melatonin co antioxidant mixtures; Radical scavenging activity; Vitamin E

Indexed keywords

5 METHOXYINDOLE; ALPHA TOCOPHEROL; ASCORBIC ACID; BENZOYL PEROXIDE; BUTYRONITRILE; INDOLE; MELATONIN; MERCAPTOETHANOL; METHACRYLIC ACID METHYL ESTER; PINOLINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DECOMPOSITION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG EFFECT; DRUG MIXTURE; POLYMERIZATION;

EID: 79952021838     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Reiter RJ, Melchiorri D, Sewerynek E, Poeggeler B, Barlow-Walden L, Chuang J, Ortiz GG and Acuna-Castroviejo D: A review of the evidence supporting melatonin's role as an antioxidant. J Pineal Res 18: 1-11, 1995.
2. Lissoni P, Chilelli M, Villa S, Cerizza L and Tancini G: Five years survival in metastatic non-small cell lung cancer patients treated with chemotherapy alone or chemotherapy and melatonin: a randomized trial. J Pineal Res 35: 12-15, 2003. (Pubitemid 36819165)
3. Srinivasan V, Spence DW, Pandi-Perumal SR, Trakht I and Cardinali DP: Therapeutic actions of melatonin in cancer: possible mechanism. Integr Cancer Ther 7: 189-203, 2008.
4. Tan DX, Reiter RJ, Manchester LC et al: Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr Top Med Chem 2: 181-197, 2002.
5. Allegra M, Reiter RJ, Tan DX, Gentile C, Tesoriere L and Livrea MA: The chemistry of melatonin's interaction with reactive species. J Pineal Res 34: 1-10, 2003. (Pubitemid 36140351)
6. Tan D-X, Hardeland R, Manchester LC, Poeggeler B, Lopez-Burillo S, Mayo JC, Sainz RM and Reiter RJ: Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical. J Pineal Res 34: 249-259, 2003. (Pubitemid 36469770)
7. Kawanishi S and Sakurai H: Differential anti-lipid peroxidative activity of melatonin Naturwissenschaften 89: 31-33, 2002.
8. Fujisawa S, Kadoma Y, Ishihara M, Shibuya K and Yokoe I: Kinetic radical-scavenging activity of melatonin. In Vivo 20: 215-220, 2006.
9. Fujisawa S and Kadoma Y: Kinetic evaluation of polyamines as radical scavengers. Anticancer Res 25: 965-969, 2005. (Pubitemid 40546870)
10. Fujisawa S, Ishihara M and Kadoma Y: Kinetics of the radical scavenging of beta-carotene-related compounds. SAR QSAR Environ Res 15: 33-41, 2004. (Pubitemid 38170953)
11. Kadoma Y, Ishihara M, Okada N and Fujisawa S: Free radical interaction between vitamin E (alpha-, beta-, gamma- and delta-tocopherol), ascorbate and flavonoids. In Vivo 20: 823-827, 2006.
12. Burton GW and Ingold KU: Beta-carotene: an unusual type of lipid antioxidant. Science 224: 569-573, 1984. (Pubitemid 14137524)
13. Gitto E, Tan DX, Reiter RJ, Karbownik M, Manchester LC, Cuzzocrea S, Fulia F and Barber I: Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrioxamine (desferoxamine) in rat liver homogenates. J Pharm Pharmacol 53: 1393-1401, 2001. (Pubitemid 32982257)
14. Valastyan S, Thakur V, Johnson A, Kumar K and Manor D: Novel transcriptional activities of vitamin E: inhibition of cholesterol biosynthesis. Biochemistry 47: 744-752, 2008. (Pubitemid 351195445)
15. Soriani M, Pietraforte D and Minetti M: Antioxidant potential of anaerobic human plasma: role of serum albumin and thiols as scavengers of carbon radicals. Arch Biochem Biophys 312: 180-188, 1994.
16. Siu AW, Reiter RJ and To CH: Pineal indoleamines and vitamin E reduce nitric oxide-induced lipid peroxidation in rat retinal homogenates. J Pineal Res 27: 122-128, 1999. (Pubitemid 29440993)
17. Pähkla R, Zilmer M, Kullisaar T and Rägo L: Comparison of the antioxidant activity of melatonin and pinoline in vitro. J Pineal Res 24: 96-101, 1998.
18. Wardman P: Reduction potential of one-electron couples involving free radicals in aqueous solution. J Phys Chem Ref Data 18: 1637-1755, 1989.
19. Mahal HS, Sharma HS and Mukherjee T: Antioxidant properties of melatonin: a pulse radiolysis study. Free Radic Biol Med 26: 557-565, 1999. (Pubitemid 29146258)
20. Wright JS, Johnson ER and DiLabio GA: Predicting the activity of phenolic antioxidants: Theoretical method, analysis of substituent effects, and application to major families of antioxidants. J Am Chem Soc 123: 1173-1183, 2001. (Pubitemid 32148182)
21. Wölfler A, Caluba HC, Abuja PM, Dohr G, Schauenstein K and Liebmann PM: Prooxidant activity of melatonin promotes fas-induced cell death in human leukemic Jurkat cells. FEBS Lett 502: 127-131, 2001. (Pubitemid 32728274)
22. Amorati R, Fiammenta F, Peduli GF and Valgimigli L: Modeling the co-antioxidant behavior of monofuntional phenols. Applications to some relavant compounds. J Org Chem 68: 9654-9658, 2003. (Pubitemid 37509872)