Analytical validation of accelerator mass spectrometry for pharmaceutical development

Bioanalysis

Volumn 2, Issue 3, 2010, Pages 469-485

  Keck, Bradly D ^a,b   Ognibene, Ted ^c   Vogel, John S ^b,c  

^a PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

^b Vitalea Science   (United States)

^c LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 14; DRUG;

ACCELERATOR MASS SPECTROMETRY; ACCURACY; ANALYTIC METHOD; CALIBRATION; DRUG BLOOD LEVEL; DRUG ISOLATION; DRUG STABILITY; DRUG URINE LEVEL; IONIZATION; ISOTOPE ANALYSIS; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRODUCT DEVELOPMENT; REPRODUCIBILITY; REVIEW; SENSITIVITY AND SPECIFICITY; VALIDATION PROCESS; ANIMAL; DRUG CONTAMINATION; DRUG DEVELOPMENT; HUMAN; METABOLISM; METHODOLOGY; STATISTICAL MODEL;

ANIMALS; DRUG CONTAMINATION; DRUG DISCOVERY; HUMANS; LINEAR MODELS; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS;

EID: 79952010877     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.10.14     Document Type: Review

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