Bed nucleus of the stria terminalis α1- and α 2-adrenoceptors differentially modulate the cardiovascular responses to exercise in rats

Neuroscience

Volumn 177, Issue , 2011, Pages 74-83

  Alves, F H F ^a   Resstel, L B M ^a   Correa, F M A ^a   Crestani, C C ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Adrenoceptors; Central nervous system; Dynamic exercise; Noradrenergic neurotransmission; Open field test; Treadmill

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BED NUCLEUS OF THE STRIA TERMINALIS; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; DYNAMIC EXERCISE; HEART RATE; MALE; MEAN ARTERIAL PRESSURE; MOTOR PERFORMANCE; NEUROMODULATION; NONHUMAN; OPEN FIELD TEST; PRESSOR RESPONSE; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; STRIA TERMINALIS; TACHYCARDIA; TREADMILL EXERCISE;

ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS; ADRENERGIC ALPHA-2 RECEPTOR ANTAGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; DIOXANES; EXERCISE TOLERANCE; IDAZOXAN; MALE; PHYSICAL CONDITIONING, ANIMAL; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, ALPHA-2; SEPTAL NUCLEI; SYNAPTIC TRANSMISSION;

EID: 79952003823     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.01.003     Document Type: Article

References (77)

1. Ally A., Hand G.A., Mitchell J.H. Cardiovascular responses to static exercise in conscious cats: effects of intracerebroventricular injection of clonidine. J Physiol 1996, 491(Pt 2):519-527.
2. Alves F.H., Crestani C.C., Gomes F.V., Guimaraes F.S., Correa F.M., Resstel L.B. Cannabidiol injected into the bed nucleus of the stria terminalis modulates baroreflex activity through 5-HT1A receptors. Pharmacol Res 2010, 62:228-236.
3. Alves F.H., Crestani C.C., Resstel L.B., Correa F.M. Cardiovascular effects of carbachol microinjected into the bed nucleus of the stria terminalis of the rat brain. Brain Res 2007, 1143:161-168.
4. Alves F.H., Crestani C.C., Resstel L.B., Correa F.M. Bed nucleus of the stria terminalis N-methyl-D-aspartate receptors and nitric oxide modulate the baroreflex cardiac component in unanesthetized rats. J Neurosci Res 2009, 87:1703-1711.
5. Amaral S.L., Michelini L.C. Validation of transit-time flowmetry for chronic measurements of regional blood flow in resting and exercising rats. Braz J Med Biol Res 1997, 30:897-908.
6. Braga D.C., Mori E., Higa K.T., Morris M., Michelini L.C. Central oxytocin modulates exercise-induced tachycardia. Am J Physiol Regul Integr Comp Physiol 2000, 278:R1474-R1482.
7. Byrum C.E., Guyenet P.G. Afferent and efferent connections of the A5 noradrenergic cell group in the rat. J Comp Neurol 1987, 261:529-542.
8. Crestani C.C., Alves F.H., Correa F.M., Guimaraes F.S., Joca S.R. Acute reversible inactivation of the bed nucleus of stria terminalis induces antidepressant-like effect in the rat forced swimming test. Behav Brain Funct 2010, 6:30.
9. Crestani C.C., Alves F.H., Resstel L.B., Correa F.M. The bed nucleus of the stria terminalis modulates baroreflex in rats. Neuroreport 2006, 17:1531-1535.
10. Crestani C.C., Alves F.H., Resstel L.B., Correa F.M. Cardiovascular effects of noradrenaline microinjection in the bed nucleus of the stria terminalis of the rat brain. J Neurosci Res 2007, 85:1592-1599.
11. Crestani C.C., Alves F.H., Resstel L.B., Correa F.M. Bed nucleus of the stria terminalis alpha(1)-adrenoceptor modulates baroreflex cardiac component in unanesthetized rats. Brain Res 2008, 1245:108-115.
12. Crestani C.C., Alves F.H., Resstel L.B., Correa F.M. Both alpha1 and alpha2-adrenoceptors mediate the cardiovascular responses to noradrenaline microinjected into the bed nucleus of the stria terminal of rats. Br J Pharmacol 2008, 153:583-590.
13. Crestani C.C., Alves F.H., Resstel L.B., Correa F.M. The bed nucleus of the stria terminalis modulates exercise-evoked cardiovascular responses in rats. Exp Physiol 2010, 95:69-79.
14. Crestani C.C., Alves F.H., Tavares R.F., Correa F.M. Role of the bed nucleus of the stria terminalis in the cardiovascular responses to acute restraint stress in rats. Stress 2009, 12:268-278.
15. Crestani C.C., Busnardo C., Tavares R.F., Alves F.H., Correa F.M. Involvement of hypothalamic paraventricular nucleus non-N-methyl-D-aspartate receptors in the pressor response to noradrenaline microinjected into the bed nucleus of the stria terminalis of unanesthetized rats. Eur J Neurosci 2009, 29:2166-2176.
16. Dampney R.A., Horiuchi J., McDowall L.M. Hypothalamic mechanisms coordinating cardiorespiratory function during exercise and defensive behaviour. Auton Neurosci 2008, 142:3-10.
17. De Angelis K., Ogawa T., Sanches I.C., Rigatto K.V., Krieger E.M., Irigoyen M.C. Impairment on cardiac output and blood flow adjustments to exercise in l-NAME-induced hypertensive rats. J Cardiovasc Pharmacol 2006, 47:371-376.
18. DiCarlo S.E., Bishop V.S. Onset of exercise shifts operating point of arterial baroreflex to higher pressures. Am J Physiol 1992, 262:H303-H307.
19. DiCarlo S.E., Bishop V.S. Central baroreflex resetting as a means of increasing and decreasing sympathetic outflow and arterial pressure. Ann N Y Acad Sci 2001, 940:324-337.
20. Dong H.W., Petrovich G.D., Watts A.G., Swanson L.W. Basic organization of projections from the oval and fusiform nuclei of the bed nuclei of the stria terminalis in adult rat brain. J Comp Neurol 2001, 436:430-455.
21. Dong H.W., Swanson L.W. Organization of axonal projections from the anterolateral area of the bed nuclei of the stria terminalis. J Comp Neurol 2004, 468:277-298.
22. Dufloth D.L., Morris M., Michelini L.C. Modulation of exercise tachycardia by vasopressin in the nucleus tractus solitarii. Am J Physiol 1997, 273:R1271-R1282.
23. Dunn J.D. Plasma corticosterone responses to electrical stimulation of the bed nucleus of the stria terminalis. Brain Res 1987, 407:327-331.
24. Dunn J.D., Williams T.J. Effect of sinoaortic denervation on arterial pressure changes evoked by bed nucleus stimulation. Brain Res Bull 1998, 46:361-365.
25. Egli R.E., Kash T.L., Choo K., Savchenko V., Matthews R.T., Blakely R.D., Winder D.G. Norepinephrine modulates glutamatergic transmission in the bed nucleus of the stria terminalis. Neuropsychopharmacology 2005, 30:657-668.
26. Fisher J.P., White M.J. Muscle afferent contributions to the cardiovascular response to isometric exercise. Exp Physiol 2004, 89:639-646.
27. Gelsema A.J., Calaresu F.R. Chemical microstimulation of the septal area lowers arterial pressure in the rat. Am J Physiol 1987, 252:R760-R767.
28. Giancola S.B., Roder S., Ciriello J. Contribution of caudal ventrolateral medulla to the cardiovascular responses elicited by activation of bed nucleus of the stria terminalis. Brain Res 1993, 606:162-166.
29. Goldsmith R.L., Bloomfield D.M., Rosenwinkel E.T. Exercise and autonomic function. Coron Artery Dis 2000, 11:129-135.
30. Gray T.S., Magnuson D.J. Neuropeptide neuronal efferents from the bed nucleus of the stria terminalis and central amygdaloid nucleus to the dorsal vagal complex in the rat. J Comp Neurol 1987, 262:365-374.
31. Hatam M., Nasimi A. Glutamatergic systems in the bed nucleus of the stria terminalis, effects on cardiovascular system. Exp Brain Res 2007, 178:394-401.
32. Higa-Taniguchi K.T., Felix J.V., Michelini L.C. Brainstem oxytocinergic modulation of heart rate control in rats: effects of hypertension and exercise training. Exp Physiol 2009, 94:1103-1113.
33. Higa-Taniguchi K.T., Silva F.C., Silva H.M., Michelini L.C., Stern J.E. Exercise training-induced remodeling of paraventricular nucleus (nor)adrenergic innervation in normotensive and hypertensive rats. Am J Physiol Regul Integr Comp Physiol 2007, 292:R1717-R1727.
34. Hill J.M., Kaufman M.P. Attenuating effects of intrathecal clonidine on the exercise pressor reflex. J Appl Physiol 1991, 70:516-522.
35. Kaufman M.P., Forster H.V. Reflexes controlling circulatory, ventilatory and airway response to exercise. Handbook of physiology, section 12, Exercise: regulation and integration of multiple systems 1996, 381-447. Oxford University Press, New York, chap. 10. L.B. Rowell, J.T. Shepherd (Eds.).
36. Kitaoka R., Fujikawa T., Miyaki T., Matsumura S., Fushiki T., Inoue K. Increased noradrenergic activity in the ventromedial hypothalamus during treadmill running in rats. J Nutr Sci Vitaminol (Tokyo) 2010, 56:185-190.
37. Kretz R. Local cobalt injection: a method to discriminate presynaptic axonal from postsynaptic neuronal activity. J Neurosci Methods 1984, 11:129-135.
38. Lambert G.W., Jonsdottir I.H. Influence of voluntary exercise on hypothalamic norepinephrine. J Appl Physiol 1998, 85:962-966.
39. Li J. Central integration of muscle reflex and arterial baroreflex in midbrain periaqueductal gray: roles of GABA and NO. Am J Physiol Heart Circ Physiol 2004, 287:H1312-H1318.
40. Li J., Potts J.T., Mitchell J.H. Effect of barodenervation on c-Fos expression in the medulla induced by static muscle contraction in cats. Am J Physiol 1998, 274:H901-H908.
41. Lomber S.G. The advantages and limitations of permanent or reversible deactivation techniques in the assessment of neural function. J Neurosci Methods 1999, 86:109-117.
42. Ludbrook J., Potocnik S.J. Circulatory changes during spontaneous motor activity: role of arterial baroreflexes. Am J Physiol 1986, 250:H426-H433.
43. Matsui H., Yamamoto C. The possible involvement of adenylate cyclase inhibition in the field potential suppression through alpha-2 adrenergic receptors in the bed nucleus of the stria terminalis. Brain Res 1984, 293:187-190.
44. Michelini L.C., Stern J.E. Exercise-induced neuronal plasticity in central autonomic networks: role in cardiovascular control. Exp Physiol 2009, 94:947-960.
45. Miki K., Yoshimoto M., Tanimizu M. Acute shifts of baroreflex control of renal sympathetic nerve activity induced by treadmill exercise in rats. J Physiol 2003, 548:313-322.
46. Moore R.Y. Catecholamin innervation of the basal forebrain. I. The septal area. J Comp Neurol 1978, 177:665-684.
47. Morrison S.F. Differential control of sympathetic outflow. Am J Physiol Regul Integr Comp Physiol 2001, 281:R683-R698.
48. Ohiwa N., Saito T., Chang H., Omori T., Fujikawa T., Asada T., Soya H. Activation of A1 and A2 noradrenergic neurons in response to running in the rat. Neurosci Lett 2006, 395:46-50.
49. Overton J.M. Influence of autonomic blockade on cardiovascular responses to exercise in rats. J Appl Physiol 1993, 75:155-161.
50. Pagliari R., Peyrin L. Norepinephrine release in the rat frontal cortex under treadmill exercise: a study with microdialysis. J Appl Physiol 1995, 78:2121-2130.
51. Paxinos G., Watson C. The rat brain in stereotaxic coordinates 1997, Academic Press, Sidney, Australia.
52. Pezuk P., Aydin E., Aksoy A., Canbeyli R. Effects of BNST lesions in female rats on forced swimming and navigational learning. Brain Res 2008, 1228:199-207.
53. Pezuk P., Goz D., Aksoy A., Canbeyli R. BNST lesions aggravate behavioral despair but do not impair navigational learning in rats. Brain Res Bull 2006, 69:416-421.
54. Phelix C.F., Liposits Z., Paull W.K. Monoamine innervation of bed nucleus of stria terminalis: an electron microscopic investigation. Brain Res Bull 1992, 28:949-965.
55. Potts J.T. Inhibitory neurotransmission in the nucleus tractus solitarii: implications for baroreflex resetting during exercise. Exp Physiol 2006, 91:59-72.
56. Raven P.B., Fadel P.J., Ogoh S. Arterial baroreflex resetting during exercise: a current perspective. Exp Physiol 2006, 91:37-49.
57. Raven P.B., Fadel P.J., Smith S.A. The influence of central command on baroreflex resetting during exercise. Exerc Sport Sci Rev 2002, 30:39-44.
58. Resstel L.B., Alves F.H., Reis D.G., Crestani C.C., Correa F.M., Guimaraes F.S. Anxiolytic-like effects induced by acute reversible inactivation of the bed nucleus of stria terminalis. Neuroscience 2008, 154:869-876.
59. Rowell L.B. Neural control of muscle blood flow: importance during dynamic exercise. Clin Exp Pharmacol Physiol 1997, 24:117-125.
60. Rowell L.B., O'Leary D.S. Reflex control of the circulation during exercise: chemoreflexes and mechanoreflexes. J Appl Physiol 1990, 69:407-418.
61. Schulz D., Canbeyli R.S. Lesion of the bed nucleus of the stria terminalis enhances learned despair. Brain Res Bull 2000, 52:83-87.
62. Sved A.F., Ito S., Madden C.J. Baroreflex dependent and independent roles of the caudal ventrolateral medulla in cardiovascular regulation. Brain Res Bull 2000, 51:129-133.
63. Swanson L.W., Hartman B.K. The central adrenergic system. An immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine-beta-hydroxylase as a marker. J Comp Neurol 1975, 163:467-505.
64. Takatsu S., Ishiwata T., Meeusen R., Sarre S., Hasegawa H. Serotonin release in the preoptic area and anterior hypothalamus is not involved in thermoregulation during low-intensity exercise in a warm environment. Neurosci Lett 2010, 482:7-11.
65. Timofeeva E., Huang Q., Richard D. Effects of treadmill running on brain activation and the corticotropin-releasing hormone system. Neuroendocrinology 2003, 77:388-405.
66. Ulrich-Lai Y.M., Herman J.P. Neural regulation of endocrine and autonomic stress responses. Nat Rev Neurosci 2009, 10:397-409.
67. Vertes R.P. Differential projections of the infralimbic and prelimbic cortex in the rat. Synapse 2004, 51:32-58.
68. Wade C.E. Response, regulation, and actions of vasopressin during exercise: a review. Med Sci Sports Exerc 1984, 16:506-511.
69. Waldrop T.G., Eldridge F.L., Iwamoto G.A., Mitchell J.H. Central neural control of respiration and circulation during exercise. Handbook of physiology, section 12, Exercise: regulation and integration of multiple systems 1996, 333-380. Oxford University Press, New York. L.B. Rowell, J.T. Shepherd, J.T. Shepherd (Eds.).
70. Waldrop T.G., Stremel R.W. Muscular contraction stimulates posterior hypothalamic neurons. Am J Physiol 1989, 256:R348-R356.
71. Williams C.A. Effect of clonidine and naloxone on the pressor response during contraction of cat hind-limb muscles. Cardiovasc Res 1985, 19:474-482.
72. Williams C.A., Blevins L.S., Paul D.J. Possible catecholaminergic-opioidergic control of blood pressure during muscular contraction. Cardiovasc Res 1987, 21:471-480.
73. Williamson J. The relevance of central command for the neural cardiovascular control of exercise. Exp Physiol 2010, 95:1043-1048.
74. Williamson J.W., Fadel P.J., Mitchell J.H. New insights into central cardiovascular control during exercise in humans: a central command update. Exp Physiol 2006, 91:51-58.
75. Winder W.W., Hagberg J.M., Hickson R.C., Ehsani A.A., McLane J.A. Time course of sympathoadrenal adaptation to endurance exercise training in man. J Appl Physiol 1978, 45:370-374.
76. Woulfe J.M., Hrycyshyn A.W., Flumerfelt B.A. Collateral axonal projections from the A1 noradrenergic cell group to the paraventricular nucleus and bed nucleus of the stria terminalis in the rat. Exp Neurol 1988, 102:121-124.
77. Yasui Y., Breder C.D., Saper C.B., Cechetto D.F. Autonomic responses and efferent pathways from the insular cortex in the rat. J Comp Neurol 1991, 303:355-374.