-
1
-
-
2542428557
-
Glutathione propagates oxidative stress triggered by myeloperoxidase in HL-60 cells: Evidence for glutathionyl radical-induced peroxidation of phospholipids and cytotoxicity
-
DOI 10.1074/jbc.M400119200
-
Borisenko GG, Martin I, Zhao Q, Amoscato AA, Tyurina YY, and Kagan VE (2004) Glutathione propagates oxidative stress triggered by myeloperoxidase in HL-60 cells. Evidence for glutathionyl radical-induced peroxidation of phospholipids and cytotoxicity. J Biol Chem 279: 23453-23462. (Pubitemid 38685656)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.22
, pp. 23453-23462
-
-
Borisenko, G.G.1
Martin, I.2
Zhao, Q.3
Amoseato, A.A.4
Tyurina, Y.Y.5
Kagan, V.E.6
-
2
-
-
43049173503
-
Mammalian heme peroxidases: From molecular mechanisms to health implications
-
DOI 10.1089/ars.2007.1927
-
Davies MJ, Hawkins CL, Pattison DI, and Rees MD (2008) Mammalian heme peroxidases: from molecular mechanisms to health implications. Antioxid Redox Signal 10:1199-1234. (Pubitemid 351634397)
-
(2008)
Antioxidants and Redox Signaling
, vol.10
, Issue.7
, pp. 1199-1234
-
-
Davies, M.J.1
Hawkins, C.L.2
Pattison, D.I.3
Rees, M.D.4
-
3
-
-
0032912983
-
Peroxidase-catalyzed pro- Versus antioxidant effects of 4- hydroxytamoxifen: Enzyme specificity and biochemical sequelae
-
DOI 10.1021/tx980137r
-
Day BW, Tyurin VA, Tyurina YY, Liu M, Facey JA, Carta G, Kisin ER, Dubey RK, and Kagan VE (1999) Peroxidase-catalyzed pro- versus antioxidant effects of 4-hydroxytamoxifen: enzyme specificity and biochemical sequelae. Chem Res Toxicol 12:28-37. (Pubitemid 29048829)
-
(1999)
Chemical Research in Toxicology
, vol.12
, Issue.1
, pp. 28-37
-
-
Day, B.W.1
Tyurin, V.A.2
Tyurina, Y.Y.3
Liu, M.4
Facey, J.A.5
Carta, G.6
Kisin, E.R.7
Dubey, R.K.8
Kagan, V.E.9
-
4
-
-
0023621645
-
An interaction of benzene metabolites reproduces the myelotoxicity observed with benzene exposure
-
Eastmond DA, Smith MT, and Irons RD (1987) An interaction of benzene metabolites reproduces the myelotoxicity observed with benzene exposure. Toxicol Appl Pharmacol 91:85-95.
-
(1987)
Toxicol Appl Pharmacol
, vol.91
, pp. 85-95
-
-
Eastmond, D.A.1
Smith, M.T.2
Irons, R.D.3
-
5
-
-
33746211294
-
Myeloperoxidase-catalyzed metabolism of etoposide to its quinone and glutathione adduct forms in HL60 cells
-
DOI 10.1021/tx0600595
-
Fan Y, Schreiber EM, Giorgianni A, Yalowich JC, and Day BW (2006) Myeloperoxidase-catalyzed metabolism of etoposide to its quinone and glutathione adduct forms in HL60 cells. Chem Res Toxicol 19:937-943. (Pubitemid 44092360)
-
(2006)
Chemical Research in Toxicology
, vol.19
, Issue.7
, pp. 937-943
-
-
Fan, Y.1
Schreiber, E.M.2
Giorgianni, A.3
Yalowich, J.C.4
Day, B.W.5
-
6
-
-
33747892853
-
Topoisomerase II and the etiology of chromosomal translocations
-
DOI 10.1016/j.dnarep.2006.05.031, PII S1568786406001716, Mechanisms of Chromosomal Translocations
-
Felix CA, Kolaris CP, and Osheroff N (2006) Topoisomerase II and the etiology of chromosomal translocations. DNA Repair (Amst) 5: 1093-1108. (Pubitemid 44291622)
-
(2006)
DNA Repair
, vol.5
, Issue.9-10
, pp. 1093-1108
-
-
Felix, C.A.1
Kolaris, C.P.2
Osheroff, N.3
-
7
-
-
0002774487
-
Environmental and nutritional phenols: Bioactivation to phenoxyl radicals and their cytotoxic and/or protective interactions with intracellular reductants
-
Goldman R, Bors W, Michel C, Day BW, and Kagan VE (1997) Environmental and nutritional phenols: bioactivation to phenoxyl radicals and their cytotoxic and/or protective interactions with intracellular reductants. Environ Nutr Interact 1:97-118.
-
(1997)
Environ Nutr Interact
, vol.1
, pp. 97-118
-
-
Goldman, R.1
Bors, W.2
Michel, C.3
Day, B.W.4
Kagan, V.E.5
-
8
-
-
0033231439
-
Myeloperoxidase-catalyzed redox-cycling of phenol promotes lipid peroxidation and thiol oxidation in HL-60 cells
-
DOI 10.1016/S0891-5849(99)00140-9, PII S0891584999001409
-
Goldman R, Claycamp GH, Sweetland MA, Sedlov AV, Tyurin VA, Kisin ER, Tyurina YY, Ritov VB, Wenger SL, Grant SG, et al. (1999) Myeloperoxidase- catalyzed redox-cycling of phenol promotes lipid peroxidation and thiol oxidation in HL-60 cells. Free Radic Biol Med 27:1050-1063. (Pubitemid 29508794)
-
(1999)
Free Radical Biology and Medicine
, vol.27
, Issue.9-10
, pp. 1050-1063
-
-
Goldman, R.1
Claycamp, G.H.2
Sweetland, M.A.3
Sedlov, A.V.4
Tyurin, V.A.5
Kisin, E.R.6
Tyurina, Y.Y.7
Ritov, V.B.8
Wenger, S.L.9
Grant, S.G.10
Kagan, V.E.11
-
9
-
-
0023552961
-
Peroxidase-catalyzed metabolism of etoposide (VP-16-213) and covalent binding of reactive intermediates to cellular macromolecules
-
Haim N, Nemec J, Roman J, and Sinha BK (1987) Peroxidase-catalyzed metabolism of etoposide (VP-16-213) and covalent binding of reactive intermediates to cellular macromolecules. Cancer Res 47:5835-5840. (Pubitemid 18018715)
-
(1987)
Cancer Research
, vol.47
, Issue.22
, pp. 5835-5840
-
-
Haim, N.1
Nemec, J.2
Roman, J.3
Sinha, B.K.4
-
10
-
-
0032168167
-
Etoposide: Four decades of development of a topoisomerase II inhibitor
-
Hande KR (1998) Etoposide: four decades of development of a topoisomerase II inhibitor. Eur J Cancer 34:1514-1521.
-
(1998)
Eur J Cancer
, vol.34
, pp. 1514-1521
-
-
Hande, K.R.1
-
11
-
-
0033789365
-
In vivo metabolism of tert-butyl hydroperoxide to methyl radicals. EPR spin-trapping and DNA methylation studies
-
Hix S, Kadiiska MB, Mason RP, and Augusto O (2000) In vivo metabolism of tert-butyl hydroperoxide to methyl radicals. EPR spin-trapping and DNA methylation studies. Chem Res Toxicol 13:1056-1064.
-
(2000)
Chem Res Toxicol
, vol.13
, pp. 1056-1064
-
-
Hix, S.1
Kadiiska, M.B.2
Mason, R.P.3
Augusto, O.4
-
12
-
-
0030445214
-
Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene
-
Hutt AM and Kalf GF (1996) Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene. Environmental Health Perspectives 104:1265-1269. (Pubitemid 27046153)
-
(1996)
Environmental Health Perspectives
, vol.104
, Issue.SUPPL. 6
, pp. 1265-1269
-
-
Hutt, A.M.1
Kalf, G.F.2
-
13
-
-
15744397830
-
Exploitation of the unusual thermodynamic properties of human myeloperoxidase in inhibitor design
-
DOI 10.1016/j.bcp.2005.02.006
-
Jantschko W, Furtmüller PG, Zederbauer M, Neugschwandtner K, Lehner I, Jakopitsch C, Arnhold J, and Obinger C (2005) Exploitation of the unusual thermodynamic properties of human myeloperoxidase in inhibitor design. Biochem Pharmacol 69:1149-1157. (Pubitemid 40417486)
-
(2005)
Biochemical Pharmacology
, vol.69
, Issue.8
, pp. 1149-1157
-
-
Jantschko, W.1
Furtmuller, P.G.2
Zederbauer, M.3
Neugschwandtner, K.4
Lehner, I.5
Jakopitsch, C.6
Arnhold, J.7
Obinger, C.8
-
14
-
-
0035502997
-
Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: Role of myeloperoxidase
-
Kagan VE, Kuzmenko AI, Tyurina YY, Shvedova AA, Matsura T, and Yalowich JC (2001) Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: role of myeloperoxidase. Cancer Res 61:7777-7784. (Pubitemid 33049364)
-
(2001)
Cancer Research
, vol.61
, Issue.21
, pp. 7777-7784
-
-
Kagan, V.E.1
Kuzmenko, A.I.2
Tyurina, Y.Y.3
Shvedova, A.A.4
Matsura, T.5
Yalowich, J.C.6
-
15
-
-
0032868183
-
Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia: Free radical/antioxidant approach
-
Kagan VE, Yalowich JC, Borisenko GG, Tyurina YY, Tyurin VA, Thampatty P, and Fabisiak JP (1999) Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia: free radical/antioxidant approach. Mol Pharmacol 56:494-506. (Pubitemid 29406876)
-
(1999)
Molecular Pharmacology
, vol.56
, Issue.3
, pp. 494-506
-
-
Kagan, V.E.1
Yalowich, J.C.2
Borisenko, G.G.3
Tyurina, Y.Y.4
Tyurin, V.A.5
Thampatty, P.6
Fabisiak, J.P.7
-
16
-
-
0027989781
-
Ascorbate is the primary reductant of the phenoxyl radical of etoposide in the presence of thiols both in cell homogenates and in model systems
-
Kagan VE, Yalowich JC, Day BW, Goldman R, Gantchev TG, and Stoyanovsky DA (1994) Ascorbate is the primary reductant of the phenoxyl radical of etoposide in the presence of thiols both in cell homogenates and in model systems. Biochemistry 33:9651-9660. (Pubitemid 24272924)
-
(1994)
Biochemistry
, vol.33
, Issue.32
, pp. 9651-9660
-
-
Kagan, V.E.1
Yalowich, J.C.2
Day, B.W.3
Goldman, R.4
Gantchev, T.G.5
Stoyanovsky, D.A.6
-
17
-
-
0024372292
-
Characterization of free radicals produced during oxidation of etoposide (VP-16) and its catechol and quinone derivatives. An ESR study
-
DOI 10.1021/bi00437a048
-
Kalyanaraman B, Nemec J, and Sinha BK (1989) Characterization of free radicals produced during oxidation of etoposide (VP-16) and its catechol and quinone derivatives. An ESR Study. Biochemistry 28:4839-4846. (Pubitemid 19151065)
-
(1989)
Biochemistry
, vol.28
, Issue.11
, pp. 4839-4846
-
-
Kalyanaraman, B.1
Nemec, J.2
Sinha, B.K.3
-
18
-
-
0030958484
-
Spontaneous DNA lesions poison human Topoisomerase IIalpha and stimulate cleavage proximal to leukemic 11q23 chromosomal breakpoints
-
DOI 10.1021/bi970507v
-
Kingma PS, Greider CA, and Osheroff N(1997) Spontaneous DNA lesions poison human topoisomerase IIalpha and stimulate cleavage proximal to leukemic 11q23 chromosomal breakpoints. Biochemistry 36:5934-5939. (Pubitemid 27257858)
-
(1997)
Biochemistry
, vol.36
, Issue.20
, pp. 5934-5939
-
-
Kingma, P.S.1
Greider, C.A.2
Osheroff, N.3
-
19
-
-
0037427860
-
A cross-platform public domain PC image-analysis program for the comet assay
-
DOI 10.1016/S1383-5718(02)00251-6, PII S1383571802002516
-
Końca K, Lankoff A, Banasik A, Lisowska H, Kuszewski T, Góźdź S, Koza Z, and Wojcik A (2003) A cross-platform public domain PC image-analysis program for the comet assay. Mutat Res 534: 15-20. (Pubitemid 36015835)
-
(2003)
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.534
, Issue.1-2
, pp. 15-20
-
-
Konca, K.1
Lankoff, A.2
Banasik, A.3
Lisowska, H.4
Kuszewski, T.5
Gozdz, S.6
Koza, Z.7
Wojcik, A.8
-
20
-
-
14944354802
-
+ cells and remain stable after clonal expansion
-
DOI 10.1182/blood-2004-07-2683
-
Libura J, Slater DJ, Felix CA, and Richardson C (2005) Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion. Blood 105:2124-2131. (Pubitemid 40731801)
-
(2005)
Blood
, vol.105
, Issue.5
, pp. 2124-2131
-
-
Libura, J.1
Slater, D.J.2
Felix, C.A.3
Richardson, C.4
-
21
-
-
0035955646
-
EPR Detection of Glutathionyl and Protein-tyrosyl Radicals during the Interaction of Peroxynitrite with Macrophages (J774)
-
DOI 10.1074/jbc.M104012200
-
Lopes de Menezes S and Augusto O (2001) EPR detection of glutathionyl and protein-tyrosyl radicals during the interaction of peroxynitrite with macrophages (J774). J Biol Chem 276:39879-39884. (Pubitemid 37391399)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.43
, pp. 39879-39884
-
-
De Lopes, M.S.1
Augusto, O.2
-
22
-
-
0035814808
-
Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints
-
DOI 10.1021/bi002361x
-
Lovett BD, Strumberg D, Blair IA, Pang S, Burden DA, Megonigal MD, Rappaport EF, Rebbeck TR, Osheroff N, Pommier YG, et al. (2001) Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints. Biochemistry 40:1159-1170. (Pubitemid 32142877)
-
(2001)
Biochemistry
, vol.40
, Issue.5
, pp. 1159-1170
-
-
Lovett, B.D.1
Strumberg, D.2
Blair, I.A.3
Pang, S.4
Burden, D.A.5
Megonigal, M.D.6
Rappaport, E.F.7
Rebbeck, T.R.8
Osheroff, N.9
Pommier, Y.G.10
Felix, C.A.11
-
23
-
-
0026522710
-
Reactions of glutathione with the catechol, the ortho-quinone and the semi-quinone free radical of etoposide. Consequences for DNA inactivation
-
Mans DR, Lafleur MV, Westmijze EJ, Horn IR, Bets D, Schuurhuis GJ, Lankelma J, and Retèl J (1992) Reactions of glutathione with the catechol, the ortho-quinone and the semi-quinone free radical of etoposide. Consequences for DNA inactivation. Biochem Pharmacol 43:1761-1768.
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 1761-1768
-
-
Mans, D.R.1
Lafleur, M.V.2
Westmijze, E.J.3
Horn, I.R.4
Bets, D.5
Schuurhuis, G.J.6
Lankelma, J.7
Retèl, J.8
-
24
-
-
33644693972
-
'In vivo' time course of plasma myeloperoxidase levels after granulocyte colony-stimulating factor-induced stem cell mobilization
-
DOI 10.1111/j.1365-3148.2005.00605.x
-
Morabito F, Tomaino A, Cristani M, Martino M, Minciullo PL, Saija A, and Gangemi S (2005) 'In vivo' time course of plasma myeloperoxidase levels after granulocyte colony-stimulating factor-induced stem cell mobilization. Transfus Med 15:425-428. (Pubitemid 43942851)
-
(2005)
Transfusion Medicine
, vol.15
, Issue.5
, pp. 425-428
-
-
Morabito, F.1
Tomaino, A.2
Cristani, M.3
Martino, M.4
Minciullo, P.L.5
Saija, A.6
Gangemi, S.7
-
25
-
-
0023845997
-
Myeloperoxidase: A myeloid cell nuclear antigen with DNA-binding properties
-
Murao S, Stevens FJ, Ito A, and Huberman E (1988) Myeloperoxidase: a myeloid cell nuclear antigen with DNA-binding properties. Proc Natl Acad Sci USA 85:1232-1236. (Pubitemid 18073983)
-
(1988)
Proceedings of the National Academy of Sciences of the United States of America
, vol.85
, Issue.4
, pp. 1232-1236
-
-
Murao, S.-I.1
Stevens, F.J.2
Ito, A.3
Huberman, E.4
-
26
-
-
0036043817
-
The comet assay. An overview of techniques
-
Olive PL (2002) The comet assay. An overview of techniques. Methods Mol Biol 203:179-194.
-
(2002)
Methods Mol Biol
, vol.203
, pp. 179-194
-
-
Olive, P.L.1
-
27
-
-
0028111790
-
The post-translational processing of myeloperoxidase is regulated by the availability of heme
-
DOI 10.1006/abbi.1994.1331
-
Pinnix IB, Guzman GS, Bonkovsky HL, Zaki SR, and Kinkade JM Jr (1994) The post-translational processing of myeloperoxidase is regulated by the availability of heme. Arch Biochem Biophys 312:447-458. (Pubitemid 24259098)
-
(1994)
Archives of Biochemistry and Biophysics
, vol.312
, Issue.2
, pp. 447-458
-
-
Pinnix, I.B.1
Guzman, G.S.2
Bonkovsky, H.L.3
Zaki, S.R.4
Kinkade Jr., J.M.5
-
28
-
-
0028009274
-
O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4
-
Relling MV, Nemec J, Schuetz EG, Schuetz JD, Gonzalez FJ, and Korzekwa KR (1994) O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. Mol Pharmacol 45:352-358. (Pubitemid 24063092)
-
(1994)
Molecular Pharmacology
, vol.45
, Issue.2
, pp. 352-358
-
-
Relling, M.V.1
Nemec, J.2
Schuetz, E.G.3
Schuetz, J.D.4
Gonzalez, F.J.5
Korzekwa, K.R.6
-
29
-
-
0024445579
-
Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity
-
Smith MT, Yager JW, Steinmetz KL, and Eastmond DA (1989) Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity. Environ Health Perspect 82:23-29. (Pubitemid 19231531)
-
(1989)
Environmental Health Perspectives
, vol.82
, pp. 23-29
-
-
Smith, M.T.1
Yager, J.W.2
Steinmetz, K.L.3
Eastmond, D.A.4
-
30
-
-
27144512265
-
+ hematopoietic stem and progenitor cells
-
DOI 10.1634/stemcells.2005-0066
-
Soucek P, Anzenbacher P, Skoumalová I, and Dvorák M (2005) Expression of cytochrome P450 genes in CD34+ hematopoietic stem and progenitor cells. Stem Cells 23:1417-1422. (Pubitemid 41504929)
-
(2005)
Stem Cells
, vol.23
, Issue.9
, pp. 1417-1422
-
-
Soucek, P.1
Anzenbacher, P.2
Skoumalova, I.3
Dvorak, M.4
-
31
-
-
0030854622
-
Considerable plasma levels of a cytotoxic etoposide metabolite in patients undergoing high-dose chemotherapy
-
DOI 10.1016/S0959-8049(97)00087-7, PII S0959804997000877
-
Stremetzne S, Jaehde U, Kasper R, Beyer J, Siegert W, and Schunack W (1997) Considerable plasma levels of a cytotoxic etoposide metabolite in patients undergoing high-dose chemotherapy. Eur J Cancer 33:978-979. (Pubitemid 27287055)
-
(1997)
European Journal of Cancer Part A
, vol.33
, Issue.6
, pp. 978-979
-
-
Stremetzne, S.1
Jaehde, U.2
Kasper, R.3
Beyer, J.4
Siegert, W.5
Schunack, W.6
-
32
-
-
0027367901
-
+ normal human hematopoietic cells
-
Strobl H, Takimoto M, Majdic O, Fritsch G, Scheinecker C, Höcker P, and Knapp W (1993) Myeloperoxidase expression in CD34+ normal human hematopoietic cells. Blood 82:2069-2078. (Pubitemid 23293989)
-
(1993)
Blood
, vol.82
, Issue.7
, pp. 2069-2078
-
-
Strobl, H.1
Takimoto, M.2
Majdic, O.3
Fritsch, G.4
Scheinecker, C.5
Hocker, P.6
Knapp, W.7
-
33
-
-
33747882412
-
Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: New insights and new questions
-
DOI 10.1016/j.dnarep.2006.05.018, PII S1568786406001595, Mechanisms of Chromosomal Translocations
-
Sung PA, Libura J, and Richardson C (2006) Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions. DNA Repair 5:1109-1118. (Pubitemid 44291612)
-
(2006)
DNA Repair
, vol.5
, Issue.9-10
, pp. 1109-1118
-
-
Sung, P.A.1
Libura, J.2
Richardson, C.3
-
34
-
-
33746256434
-
Mechanisms of cardiolipin oxidation by cytochrome c: Relevance to pro- And antiapoptotic functions of etoposide
-
DOI 10.1124/mol.106.022731
-
Tyurina YY, Kini V, Tyurin VA, Vlasova II, Jiang J, Kapralov AA, Belikova NA, Yalowich JC, Kurnikov IV, and Kagan VE (2006) Mechanisms of cardiolipin oxidation by cytochrome c: relevance to pro- and antiapoptotic functions of etoposide. Mol Pharmacol 70:706-717. (Pubitemid 44092331)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.2
, pp. 706-717
-
-
Tyurina, Y.Y.1
Kini, V.2
Tyurin, V.A.3
Vlasova, I.I.4
Jiang, J.5
Kapralov, A.A.6
Belikova, N.A.7
Yalowich, J.C.8
Kurnikov, I.V.9
Kagan, V.E.10
-
35
-
-
0028957350
-
Phenoxyl radicals of etoposide (VP-16) can directly oxidize intracellular thiols: Protective versus damaging effects of phenolic antioxidants
-
Tyurina YY, Tyurin VA, Yalowich JC, Quinn PJ, Claycamp HG, Schor NF, Pitt BR, and Kagan VE (1995) Phenoxyl radicals of etoposide (VP-16) can directly oxidize intracellular thiols: protective versus damaging effects of phenolic antioxidants. Toxicol Appl Pharmacol 131:277-288.
-
(1995)
Toxicol Appl Pharmacol
, vol.131
, pp. 277-288
-
-
Tyurina, Y.Y.1
Tyurin, V.A.2
Yalowich, J.C.3
Quinn, P.J.4
Claycamp, H.G.5
Schor, N.F.6
Pitt, B.R.7
Kagan, V.E.8
-
36
-
-
0025684823
-
Tyrosinase-induced free radical formation from VP-16,213: Relationship to cytotoxicity
-
Usui N and Sinha BK (1990) Tyrosinase-induced free radical formation from VP-16,213: relationship to cytotoxicity. Free Radic Res Commun 10:287-293.
-
(1990)
Free Radic Res Commun
, vol.10
, pp. 287-293
-
-
Usui, N.1
Sinha, B.K.2
-
37
-
-
0037195783
-
Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation
-
DOI 10.1074/jbc.M209124200
-
Zhang R, Brennan ML, Shen Z, MacPherson JC, Schmitt D, Molenda CE, and Hazen SL (2002) Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation. J Biol Chem 277:46116-46122. (Pubitemid 35417600)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.48
, pp. 46116-46122
-
-
Zhang, R.1
Brennan, M.-L.2
Shen, Z.3
MacPherson, J.C.4
Schmitt, D.5
Molenda, C.E.6
Hazen, S.L.7
-
38
-
-
2442616994
-
Plasma Etoposide Catechol Increases in Pediatric Patients Undergoing Multiple-Day Chemotherapy with Etoposide
-
DOI 10.1158/1078-0432.CCR-03-0221
-
Zheng N, Felix CA, Pang S, Boston R, Moate P, Scavuzzo J, and Blair IA (2004) Plasma etoposide catechol increases in pediatric patients undergoing multiple-day chemotherapy with etoposide. Clin Cancer Res 10:2977-2985. (Pubitemid 38619673)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.9
, pp. 2977-2985
-
-
Zheng, N.1
Felix, C.A.2
Pang, S.3
Boston, R.4
Moate, P.5
Scavuzzo, J.6
Blair, I.A.7
-
39
-
-
33845347814
-
Characterization of an etoposide-glutathione conjugate derived from metabolic activation by human cytochrome P450
-
DOI 10.2174/138920006779010638
-
Zheng N, Pang S, Oe T, Felix CA, Wehrli S, and Blair IA (2006) Characterization of an etoposide-glutathione conjugate derived from metabolic activation by human cytochrome p450. Curr Drug Metab 7:897-911. (Pubitemid 44873714)
-
(2006)
Current Drug Metabolism
, vol.7
, Issue.8
, pp. 897-911
-
-
Zheng, N.1
Pang, S.2
Oe, T.3
Felix, C.A.4
Wehrli, S.5
Blair, I.A.6
-
40
-
-
4143090798
-
Kinetics and regulation of cytochrome P450-mediated etoposide metabolism
-
Zhuo X, Zheng N, Felix CA, and Blair IA (2004) Kinetics and regulation of cytochrome P450-mediated etoposide metabolism. Drug Metab Dispos 32:993-1000. (Pubitemid 39096060)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.9
, pp. 993-1000
-
-
Zhuo, X.1
Zheng, N.2
Felix, C.A.3
Blair, I.A.4
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