Tumor angiogenesis in keratocystic odontogenic tumor assessed by using CD-105 antigen

Journal of Oral Pathology and Medicine

Volumn 40, Issue 3, 2011, Pages 263-269

  Gadbail, Amol Ramchandra ^a   Hande, Alka ^a   Chaudhary, Minal ^a   Nikam, Atul ^a   Gawande, Madhuri ^a   Patil, Swati ^a   Tekade, Satyajit ^b   Gondivkar, Shailesh ^c  

^a DATTA MEGHE INSTITUTE OF MEDICAL SCIENCES   (India)

^b Modern Dental College and Research Centre ^*  (India)

^c MGV's KBH Dental College and Hospital   (India)

Author keywords

Angiogenesis; CD105 (Endoglin); Dentigerous cyst; Keratocystic odontogenic tumor (KCOT); Ki 67

Indexed keywords

ENDOGLIN; KI 67 ANTIGEN;

ANGIOGENESIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KERATOCYSTIC ODONTOGENIC TUMOR; MORPHOMETRICS; MOUTH MUCOSA; ODONTOGENIC KERATOCYST; ODONTOGENIC TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; TERATOMA;

ANTIGENS, CD; BASEMENT MEMBRANE; CELL PROLIFERATION; DENTIGEROUS CYST; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; EPITHELIUM; HUMANS; KI-67 ANTIGEN; MICROVESSELS; MOUTH MUCOSA; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; ODONTOGENIC TUMORS; RECEPTORS, CELL SURFACE;

EID: 79951890267     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2010.00962.x     Document Type: Article

References (52)

1. Blanas N, Freund B, Schwartz M, Forst IM. Systemic review of the treatment and prognosis of the odontogenic keratocyst. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000; 90: 553-8.
2. Myoung H, Hong SP, Hong SD, Lee JI. Odontogenic keratocyst: review of 256 cases for recurrence and clinicopathologic parameters. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001; 91: 328-33.
3. Chirapathomsakul D, Sastravaha P, Jansisyanont P. A review of odontogenic keratocysts and the behavior of recurrences. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 101: 5-9.
4. Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 1. Clinical and early experimental evidence of aggressive behaviour Oral Oncol 2002; 38: 219-26.
5. Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 2. Proliferation and genetic studies Oral Oncol 2002; 38: 323-31.
6. Barreto DC, Gomez RS, Bale AE, Boson WL, De Marco L. PTCH gene mutation in odontogenic keratocysts. J Dent Res 2000; 79: 1418-22.
7. Thosaporn W, Iamaroon A, Pongsiriwet S, Ng KH. A comparative study of epithelial cell proliferation between the odontogenic keratocyst, orthokeratinized odontogenic cyst, dentigerous cyst, and ameloblastoma. Oral Dis 2004; 10: 22-6.
8. Kolar Z, Geierova M, Bouchal J, Pazdera J, Zboril V, Tvrdy P. Immunohistochemical analysis of the biological potential of odontogenic keratocysts. J Oral Pathol Med 2006; 35: 75-80.
9. Tsuneki M, Cheng J, Maruyama S, Ida-Yonemochi H, Nakajima M, Saku T. Perlecan-rich epithelial linings as a background of proliferative potentials of keratocystic odontogenic tumour. J Oral Pathol Med 2008; 37: 287-93.
10. Gadbail AR, Chaudhary M, Patil S, Gawande M. Actual proliferating index and p53 protein expression as prognostic marker in odontogenic cysts. Oral Dis 2009; 15: 490-8.
11. Philipsen HP. Keratocystic odontogenic tumor. In: Barnes L, Eveson JW, Reichart P, Sidransky D eds. World Health Organization classification of tumors. Pathology and genetics of head and neck tumors. Lyon: IARC Press, 2005; 306-7.
12. Shear M, ed. Dentigerous cyst. In: Cysts of the oral regions, 3rd edn. Oxford: Butterworth-Heinemann, 1992; 75-98.
13. De Oliveira MD, De Miranda JL, De Amorim RF, De Souza LB, De Almeida Freitas R. Tenascin and fibronectin expression in odontogenic cysts. J Oral Pathol Med 2004; 33: 354-9.
14. De Wever O, Mareel M. Role of tissue stroma in cancer cell invasion. J Pathol 2003; 200: 429-47.
15. Kumar V, Abbas AK, Fausto N. In robbins and cotran pathologic basis of diseases, 7th edn. Philadelphia: Saunders, 2004: 309-11.
16. Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407: 249-57.
17. Folkman J. Angiogenesis in cancer, vascular, rheumatoid, and other disease. Nat Med 1995; 1: 27-31.
18. Hillen F, Griffioen AW. Tumour vascularization: sprouting angiogenesis and beyond. Cancer Metastasis Rev 2007; 26: 489-502.
19. Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis: correlation in invasion breast carcinoma. N Engl J Med 1991; 324: 1-8.
20. Kumamoto H, Ohki K, Ooya K. Association between vascular endothelial growth factor (VEGF) expression and tumor angiogenesis in ameloblastomas. J Oral Pathol Med 2002; 31: 28-34.
21. Tao X, Huang Y, Li R, et al. Assessment of local angiogenesis and vascular endothelial growth factor in the patients with atrophic erosive and reticular lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 103: 661-9.
22. Marioni G, Alessandro ED, Giacomelli L, Staffieri A. CD105 is a marker of tumour vasculature and a potential target for the treatment of head and neck squamous cell carcinoma. J Oral Pathol Med 2010; 39: 361-7.
23. Du JR, Jiang Y, Zhang YM, Fu H. Vascular endothelial growth factor and microvascular density in esophageal and gastric carcinomas. World J Gastroenterol 2003; 9: 1604-6.
24. Sharma S, Sharma MC, Sarkar C. Morphology of angiogenesis in human cancer: a conceptual overview, histoprognostic perspective and significance of neoangiogenesis. Histopathology 2005; 46: 481.
25. Fonsatti E, Altomonte M, Nicotra MR, Natali PG, Maio M. Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels. Oncogene 2003; 22: 6557-63.
26. Sanchez-Elsner T, Botella LM, Velasco B, Langa C, Bernabeu C. Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways. J Biol Chem 2002; 277: 43799-808.
27. Goumans MJ, Lebrin F, Valdimarsdottir G. Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways. Trends Cardiovasc Med 2003; 13: 301-7.
28. Minhajat R, Mori D, Yamasaki F, Sugita Y, Satoh T, Tokunaga O. Organ-specific endoglin (CD105) expression in the angiogenesis of human cancers. Pathol Int 2006; 56: 717-23.
29. Ding S, Li C, Lin S, et al. Comparative evaluation of microvessel density determined by CD34 or CD105 in benign and malignant gastric lesions. Hum Pathol 2006; 37: 861-6.
30. Brown DC, Gatter KC. Ki67 protein: the immaculate deception? Histopathology 2002; 40: 2-11.
31. Kichi E, Enokiya Y, Muramatsu T, et al. Cell proliferation, apoptosis, and apoptosis-related factors in odontogenic keratocysts and in dentigerous cysts. J Oral Pathol Med 2005; 34: 280-6.
32. Kim DK, Ahn SG, Kim J, Yoon JH. Comparison of Ki-67 expression and apoptosis in the odontogenic keratocyst associated with or without and impacted tooth in addition to unilocular and multilocular varieties. Yonsei Med J 2003; 44: 841-6.
33. Saracogly U, Kurt B, Gunhan O, Guven O. MIB-1 expression in odontogenic epithelial rests, epithelium of healthy oral mucosa and epithelium of selected odontogenic cysts An immunohistochemical study. Intl J Oral Maxillofac Surg 2005; 34: 432-5.
34. Li T, Browne RM, Matthews JB. Epithelial cell proliferation in odontogenic keratocysts: Immunocytochemical study of Ki67 in simple, recurrent, and basal cell naevus syndrome (BCNS)-associated lesions. J Oral Pathol Med 1995; 24: 221-6.
35. Browne RM. The pathogenesis of odontogenic cysts: a review. J Oral Pathol 1975; 4: 31-46.
36. Amorim RF, Godoy GP, GalvãO HC, Souza LB, Freitas RA. Immunohistochemical assessment of extracellular matrix components in syndrome and non-syndrome odontogenic keratocysts. Oral Dis 2004; 10: 265-70.
37. Da Silva TA, Batista AC, Mendonça EF, Leles CR, Fukada S, Cunha FQ. Comparative expression of RANK, RANKL, and OPG in keratocystic odontogenic tumours, ameloblastomas, and dentigerous cysts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 105: 333-41.
38. Poomsawat S, Punyasingh J, Weerapradist W. Expression of basement membrane components in odontogenic cysts. Oral Dis 2006; 12: 290-6.
39. Vedtofte P, Holmstrup P, Dabelsteen E. Human odontogenic keratocyst transplants in nude mice. Scand J Dent Res 1982; 90: 306-14.
40. Hirshberg A, Buchner A, Dayan D. The central odontogenic fibroma and the hyperplastic dental follicle: a study with picrosirius red and polarizing microscopy. J Oral Pathol Med 1996; 25: 125-7.
41. Hirshberg A, Sherman S, Buchner A, Dayan D. Collagen fibers in the wall of odontogenic keratocysts: a study with picrosirius red and polarizing microscopy. J Oral Pathol Med 1999; 28: 410-2.
42. Saadi RS, Liu YL, Nathan G, Celebrezze J, Medich D, Silverman JF. Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in colorectal cancer. Mod Pathol 2004; 17: 197-203.
43. Marioni G, Marino F, Giacomelli L, et al. Endoglin expression is associated with poor oncologic outcome in oral and oropharyngeal carcinoma. Acta Otolaryngol 2006; 126: 633-9.
44. Alaeddini M, Salah S, Dehghan F, Eshghyar N, Etemad-Moghadam S. Comparison of angiogenesis in keratocystic odontogenic tumours, dentigerous cysts and ameloblastomas. Oral Dis 2009; 15: 422-7.
45. Kurokava H, Matsumoto S, Murata T, et al. Immunohistochemical study of Syndecan 2 down regulation and the expression of p53 protein or Ki-67 antigen in oral Leukoplakia with or withought dysplasia. J Oral Pathol Med 2003; 32: 513-21.
46. Pazouki S, Chisholm DM, Adi MM, et al. The association between tumor progression and vascularity in the oral mucosa. J Pathol 1997; 183: 39-43.
47. Dellas A, Moch H, Schultheiss E, et al. Angiogenesis in cervical neoplasia: microvessel quantitation in precancerous lesions and invasive carcinomas with clinicopathological correlations. Gynecol Oncol 1997; 67: 27-33.
48. El-Labban NG, Aghabeigi B. A comparative stereologic and ultrastructural study of blood vessels in odontogenic keratocysts and dentigerous cysts. J Oral Pathol Med 1990; 19: 442-6.
49. Vered M, Shohat I, Buchner A, Dayan D. Myofibroblasts in stroma of odontogenic cysts ant tumors can contribute to variations in the biological behaviour of lesions. Oral Oncol 2005; 41: 1028-33.
50. Katase N, Nagatsuka H, Tsujigiwa H, et al. Analysis of the neoplastic nature and biological potential of sporadic and nevoid basal cell carcinoma syndrome associated keratocystic odontogenic tumor. J Oral Pathol Med 2007; 36: 550-4.
51. Vlodavsky I, Abboud-Jarrous G, Elkin M, et al. The impact of heparanese and heparin on cancer metastasis and angiogenesis. Pathophysiol Haemost Thromb. 2006; 35: 116-27.
52. Mitrou GK, Tosios KI, Kyroudi A, Sklavounou A. Odotogenic keratocyst expresses vascular endothelial growth factor: an immunohistochemical study. J Oral Pathol Med 2009; 38: 470-5.