Differential subcellular distribution of rat brain dopamine receptors and subtype-specific redistribution induced by cocaine

Molecular and Cellular Neuroscience

Volumn 46, Issue 3, 2011, Pages 645-654

  Voulalas, Pamela J ^b   Schetz, John ^c   Undieh, Ashiwel S ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Cellular subdomains; Cocaine; D1 dopamine receptor; D2 dopamine receptor; D5 dopamine receptor; Lipid rafts; Receptor translocation

Indexed keywords

COCAINE; DETERGENT; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 5 RECEPTOR; RECEPTOR PROTEIN; RECEPTOR SUBTYPE;

ANIMAL TISSUE; ARTICLE; BRAIN; CAVEOLA; CELL FRACTIONATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DENSITY GRADIENT CENTRIFUGATION; FRONTAL CORTEX; IMMUNOREACTIVITY; LIPID RAFT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR SOLUBILIZATION; SUCROSE GRADIENT;

ANIMALS; CELL MEMBRANE; COCAINE; CYTOPLASM; DETERGENTS; DOPAMINE UPTAKE INHIBITORS; FRONTAL LOBE; MALE; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE; SUBCELLULAR FRACTIONS;

RATTUS;

EID: 79951851111     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2011.01.004     Document Type: Article

References (67)

1. Agnati L.F., Ferre S., Lluis C., Franco R., Fuxe K. Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons. Pharmacol. Rev. 2003, 55:509-550.
2. Aldridge G.M., Podrebarac D.M., Greenough W.T., Weiler I.J. The use of total protein stains as loading controls: an alternative to high-abundance single-protein controls in semi-quantitative immunoblotting. J. Neurosci. Meth. 2008, 172:250-254.
3. Allen J.A., Halverson-Tamboli R.A., Rasenick M.M. Lipid raft microdomains and neurotransmitter signalling. Nat. Rev. Neurosci. 2007, 8:128-140.
4. Anderson S.M., Pierce R.C. Cocaine-induced alterations in dopamine receptor signaling: implications for reinforcement and reinstatement. Pharmacol. Ther. 2005, 106:389-403.
5. Archibald K., Molnar E., Henley J.M. Differential changes in the subcellular distribution of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate and N-methyl-d-aspartate receptors in neonate and adult rat cortex. Neurosci. Lett. 1999, 270:49-52.
6. Ariano M.A., Wang J., Noblett K.L., Larson E.R., Sibley D.R. Cellular distribution of the rat D1B receptor in central nervous system using anti-receptor antisera. Brain Res. 1997, 746:141-150.
7. Balfour D.J., Wright A.E., Benwell M.E., Birrell C.E. The putative role of extra-synaptic mesolimbic dopamine in the neurobiology of nicotine dependence. Behav. Brain Res. 2000, 113:73-83.
8. Bergson C., Mrzljak L., Smiley J.F., Pappy M., Levenson R., Goldman-Rakic P.S. Regional, cellular, and subcellular variations in the distribution of D1 and D5 dopamine receptors in primate brain. J. Neurosci. 1995, 15:7821-7836.
9. Berke J.D., Hyman S.E. Addiction, dopamine, and the molecular mechanisms of memory. Neuron 2000, 25:515-532.
10. Berthet A., Porras G., Doudnikoff E., Stark H., Cador M., Bezard E., Bloch B. Pharmacological analysis demonstrates dramatic alteration of D1 dopamine receptor neuronal distribution in the rat analog of l-DOPA-induced dyskinesia. J. Neurosci. 2009, 29:4829-4835.
11. Brady J.D., Rich T.C., Le X., Stafford K., Fowler C.J., Lynch L., Karpen J.W., Brown R.L., Martens J.R. Functional role of lipid raft microdomains in cyclic nucleotide-gated channel activation. Mol. Pharmacol. 2004, 65:503-511.
12. Canobbio I., Trionfini P., Guidetti G.F., Balduini C., Torti M. Targeting of the small GTPase Rap2b, but not Rap1b, to lipid rafts is promoted by palmitoylation at Cys176 and Cys177 and is required for efficient protein activation in human platelets. Cell. Signal. 2008, 20:1662-1670.
13. Cho D.I., Beom S., Van Tol H.H., Caron M.G., Kim K.M. Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors. Biochem. Biophys. Res. Commun. 2006, 350:634-640.
14. Ciliax B.J., Nash N., Heilman C., Sunahara R., Hartney A., Tiberi M., Rye D.B., Caron M.G., Niznik H.B., Levey A.I. Dopamine D(5) receptor immunolocalization in rat and monkey brain. Synapse 2000, 37:125-145.
15. Donati R.J., Rasenick M.M. Chronic antidepressant treatment prevents accumulation of gsalpha in cholesterol-rich, cytoskeletal-associated, plasma membrane domains (lipid rafts). Neuropsychopharmacology 2005, 30:1238-1245.
16. Dumartin B., Caille I., Gonon F., Bloch B. Internalization of D1 dopamine receptor in striatal neurons in vivo as evidence of activation by dopamine agonists. J. Neurosci. 1998, 18:1650-1661.
17. Dumartin B., Jaber M., Gonon F., Caron M.G., Giros B., Bloch B. Dopamine tone regulates D1 receptor trafficking and delivery in striatal neurons in dopamine transporter-deficient mice. Proc. Natl Acad. Sci. USA 2000, 97:1879-1884.
18. Fiorentini C., Gardoni F., Spano P., Di Luca M., Missale C. Regulation of dopamine D1 receptor trafficking and desensitization by oligomerization with glutamate N-methyl-d-aspartate receptors. J. Biol. Chem. 2003, 278:20196-20202.
19. Fishburn C.S., Elazar Z., Fuchs S. Differential glycosylation and intracellular trafficking for the long and short isoforms of the D2 dopamine receptor. J. Biol. Chem. 1995, 270:29819-29824.
20. Friedman E., Wang H.Y. Prenatal cocaine exposure alters signal transduction in the brain D1 dopamine receptor system. Ann. NY Acad. Sci. 1998, 846:238-247.
21. Friedman E., Yadin E., Wang H.Y. Effect of prenatal cocaine on dopamine receptor-G protein coupling in mesocortical regions of the rabbit brain. Neuroscience 1996, 70:739-747.
22. Gerfen C.R. D1 dopamine receptor supersensitivity in the dopamine-depleted striatum animal model of Parkinson's disease. Neuroscientist 2003, 9:455-462.
23. Graybiel A.M., Aosaki T., Flaherty A.W., Kimura M. The basal ganglia and adaptive motor control. Science 1994, 265:1826-1831.
24. Guigoni C., Doudnikoff E., Li Q., Bloch B., Bezard E. Altered D(1) dopamine receptor trafficking in parkinsonian and dyskinetic non-human primates. Neurobiol. Dis. 2007, 26:452-463.
25. Hancock J.F. Lipid rafts: contentious only from simplistic standpoints. Nat. Rev. Mol. Cell Biol. 2006, 7:456-462.
26. Hanyaloglu A.C., von Zastrow M. Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu. Rev. Pharmacol. Toxicol. 2008, 48:537-568.
27. Harding A.S., Hancock J.F. Using plasma membrane nanoclusters to build better signaling circuits. Trends Cell Biol. 2008, 18:364-371.
28. He Y., Yu L.P., Jin G.Z. Differential distributions and trafficking properties of dopamine D1 and D5 receptors in nerve cells. Neurosci. Bull. 2009, 25:43-53.
29. Head B.P., Patel H.H., Roth D.M., Murray F., Swaney J.S., Niesman I.R., Farquhar M.G., Insel P.A. Microtubules and actin microfilaments regulate lipid raft/caveolae localization of adenylyl cyclase signaling components. J. Biol. Chem. 2006, 281:26391-26399.
30. Henry D.J., White F.J. Repeated cocaine administration causes persistent enhancement of D1 dopamine receptor sensitivity within the rat nucleus accumbens. J. Pharmacol. Exp. Ther. 1991, 258:882-890.
31. Jones L.B., Stanwood G.D., Reinoso B.S., Washington R.A., Wang H.Y., Friedman E., Levitt P. In utero cocaine-induced dysfunction of dopamine D1 receptor signaling and abnormal differentiation of cerebral cortical neurons. J. Neurosci. 2000, 20:4606-4614.
32. Karpa K.D., Lidow M.S., Pickering M.T., Levenson R., Bergson C. N-linked glycosylation is required for plasma membrane localization of D5, but not D1, dopamine receptors in transfected mammalian cells. Mol. Pharmacol. 1999, 56:1071-1078.
33. Kelly J.F., Storie K., Skamra C., Bienias J., Beck T., Bennett D.A. Relationship between Alzheimer's disease clinical stage and Gq/11 in subcellular fractions of frontal cortex. J. Neural Transm. 2005, 112:1049-1056.
34. Khan Z.U., Gutierrez A., Martin R., Penafiel A., Rivera A., de la Calle A. Dopamine D5 receptors of rat and human brain. Neuroscience 2000, 100:689-699.
35. Klawans H.L., Margolin D.I., Dana N., Crosset P. Supersensitivity to d-amphetamine- and apomorphine-induced stereotyped behavior induced by chronic d-amphetamine administration. J. Neurol. Sci. 1975, 25:283-289.
36. Kong M.M., Hasbi A., Mattocks M., Fan T., O'Dowd B.F., George S.R. Regulation of D1 dopamine receptor trafficking and signaling by caveolin-1. Mol. Pharmacol. 2007, 72:1157-1170.
37. Korf J., Loopuijt L.D. Synaptic and non-synaptic striatal dopamine D2 receptors: possible implications in normal and pathological behaviour. Acta Morphol. Neerl. Scand. 1988, 26:177-190.
38. Lee S.P., Xie Z., Varghese G., Nguyen T., O'Dowd B.F., George S.R. Oligomerization of dopamine and serotonin receptors. Neuropsychopharmacology 2000, 23:S32-S40.
39. Lee F.J., Xue S., Pei L., Vukusic B., Chery N., Wang Y., Wang Y.T., Niznik H.B., Yu X.M., Liu F. Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor. Cell 2002, 111:219-230.
40. Lee S.P., So C.H., Rashid A.J., Varghese G., Cheng R., Lanca A.J., O'Dowd B.F., George S.R. Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal. J. Biol. Chem. 2004, 279:35671-35678.
41. Luedtke R.R., Griffin S.A., Conroy S.S., Jin X., Pinto A., Sesack S.R. Immunoblot and immunohistochemical comparison of murine monoclonal antibodies specific for the rat D1a and D1b dopamine receptor subtypes. J. Neuroimmunol. 1999, 101:170-187.
42. McGinty J.F., Shi X.D., Schwendt M., Saylor A., Toda S. Regulation of psychostimulant-induced signaling and gene expression in the striatum. J. Neurochem. 2008, 104:1440-1449.
43. Memo M., Lovenberg W., Hanbauer I. Agonist-induced subsensitivity of adenylate cyclase coupled with a dopamine receptor in slices from rat corpus striatum. Proc. Natl Acad. Sci. USA 1982, 79:4456-4460.
44. Mishra R.K., Gardner E.L., Katzman R., Makman M.H. Enhancement of dopamine-stimulated adenylate cyclase activity in rat caudate after lesions in substantia nigra: evidence for denervation supersensitivity. Proc. Natl Acad. Sci. USA 1974, 71:3883-3887.
45. Oda S., Funato H., Adachi-Akahane S., Ito M., Okada A., Igarashi H., Yokofujita J., Kuroda M. Dopamine D5 receptor immunoreactivity is differentially distributed in GABAergic interneurons and pyramidal cells in the rat medial prefrontal cortex. Brain Res. 2010, 1329:89-102.
46. Olsen M., Krog L., Edvardsen K., Skovgaard L.T., Bock E. Intact transmembrane isoforms of the neural cell adhesion molecule are released from the plasma membrane. Biochem. J. 1993, 295(Pt 3):833-840.
47. Ostrom R.S., Insel P.A. The evolving role of lipid rafts and caveolae in G protein-coupled receptor signaling: implications for molecular pharmacology. Br. J. Pharmacol. 2004, 143:235-245.
48. Panchalingam S., Undie A.S. Physicochemical modulation of agonist-induced [35s]GTPgammaS binding: implications for coexistence of multiple functional conformations of dopamine D1-like receptors. J. Recept. Signal Transduct. Res. 2005, 25:125-146.
49. Paspalas C.D., Goldman-Rakic P.S. Microdomains for dopamine volume neurotransmission in primate prefrontal cortex. J. Neurosci. 2004, 24:5292-5300.
50. Patel H.H., Murray F., Insel P.A. G-protein-coupled receptor-signaling components in membrane raft and caveolae microdomains. Handb. Exp. Pharmacol. 2008, 167-184.
51. Patra S.K. Dissecting lipid raft facilitated cell signaling pathways in cancer. Biochim. Biophys. Acta 2008, 1785:182-206.
52. Pei L., Lee F.J., Moszczynska A., Vukusic B., Liu F. Regulation of dopamine D1 receptor function by physical interaction with the NMDA receptors. J. Neurosci. 2004, 24:1149-1158.
53. Pin J.P., Neubig R., Bouvier M., Devi L., Filizola M., Javitch J.A., Lohse M.J., Milligan G., Palczewski K., Parmentier M., Spedding M. International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers. Pharmacol. Rev. 2007, 59:5-13.
54. Rivera A., Alberti I., Martin A.B., Narvaez J.A., de la Calle A., Moratalla R. Molecular phenotype of rat striatal neurons expressing the dopamine D5 receptor subtype. Eur. J. Neurosci. 2002, 16:2049-2058.
55. Sadowski L., Pilecka I., Miaczynska M. Signaling from endosomes: location makes a difference. Exp. Cell Res. 2009, 315:1601-1609.
56. Sahu A., Tyeryar K.R., Vongtau H.O., Sibley D.R., Undieh A.S. D5 dopamine receptors are required for dopaminergic activation of phospholipase C. Mol. Pharmacol. 2009, 75:447-453.
57. Sidhu A. A novel affinity purification of D-1 dopamine receptors from rat striatum. J. Biol. Chem. 1990, 265:10065-10072.
58. Sidhu A., Kimura K., Vachvanichsanong P. Induction of G protein-independent agonist high-affinity binding sites of D-1 dopamine receptors by beta-mercaptoethanol. Biochemistry 1994, 33:11246-11253.
59. Stanwood G.D., Levitt P. Prenatal exposure to cocaine produces unique developmental and long-term adaptive changes in dopamine D1 receptor activity and subcellular distribution. J. Neurosci. 2007, 27:152-157.
60. Sun W., Ginovart N., Ko F., Seeman P., Kapur S. In vivo evidence for dopamine-mediated internalization of D2-receptors after amphetamine: differential findings with [3H]raclopride versus [3H]spiperone. Mol. Pharmacol. 2003, 63:456-462.
61. Undie A.S., Friedman E. Stimulation of a dopamine D1 receptor enhances inositol phosphates formation in rat brain. J. Pharmacol. Exp. Ther. 1990, 253:987-992.
62. Vazquez V., Weiss S., Giros B., Martres M.P., Dauge V. Maternal deprivation and handling modify the effect of the dopamine D3 receptor agonist, BP 897 on morphine-conditioned place preference in rats. Psychopharmacology (Berl) 2007, 193:475-486.
63. Vickery R.G., von Zastrow M. Distinct dynamin-dependent and -independent mechanisms target structurally homologous dopamine receptors to different endocytic membranes. J. Cell Biol. 1999, 144:31-43.
64. Yao K., Paliyath G., Humphrey R.W., Hallett F.R., Thompson J.E. Identification and characterization of nonsedimentable lipid-protein microvesicles. Proc. Natl Acad. Sci. USA 1991, 88:2269-2273.
65. Yasuda K., Nagafuku M., Shima T., Okada M., Yagi T., Yamada T., Minaki Y., Kato A., Tani-Ichi S., Hamaoka T., Kosugi A. Cutting edge: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells. J. Immunol. 2002, 169:2813-2817.
66. Yu P., Yang Z., Jones J.E., Wang Z., Owens S.A., Mueller S.C., Felder R.A., Jose P.A. D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells. Kidney Int. 2004, 66:2167-2180.
67. Zhang J., Vinuela A., Neely M.H., Hallett P.J., Grant S.G., Miller G.M., Isacson O., Caron M.G., Yao W.D. Inhibition of the dopamine D1 receptor signaling by PSD-95. J. Biol. Chem. 2007, 282:15778-15789.