Synthetic Versus Natural Cat Odorant Effects on Rodent Behavior and Medial Amygdala Plasticity

Behavioral Neuroscience

Volumn 125, Issue 1, 2011, Pages 124-129

  Collins, Dawn R ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Anxiety; Behavior; LTP; Predator; Stress

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; AVOIDANCE BEHAVIOR; CONTROLLED STUDY; EX VIVO STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEAR; FREEZING; HABITUATION; LONG TERM POTENTIATION; MALE; MEDIAL AMYGDALA; NERVE CELL PLASTICITY; NONHUMAN; ODOR; PERCEPTION; RAT; RODENT; SMELLING;

AMYGDALA; ANIMALS; ANXIETY; AVOIDANCE LEARNING; CATS; MALE; NEURONAL PLASTICITY; ODORS; PHEROMONES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 79951834269     PISSN: 07357044     EISSN: 19390084     Source Type: Journal    
DOI: 10.1037/a0021955     Document Type: Article

References (44)

1. Adamec R.E., Blundell J., Burton P. Neural circuit changes mediating lasting brain and behavioral response to predator stress. Neuroscience and Biobehavioral Reviews 2005, 29:1225-1241.
2. Apfelbach R., Blanchard C.D., Blanchard R.J., Hayes R.A., McGregor I.S. The effects of predator odors in mammalian prey species: A review of field and laboratory studies. Neuroscience and Biobehavioral Reviews 2005, 29:1123-1144.
3. Bauer E.P., LeDoux J.E., Nader K. Fear conditioning and LTP in the lateral amygdala are sensitive to the same stimulus contingencies. Nature Neuroscience 2001, 4:687-688.
4. Blanchard D.C., Canteras N.S., Markham C.M., Pentkowski N.S., Blanchard R.J. Lesions of structures showing FOS expression to cat presentation: Effects on responsivity to a Cat, Cat odor, and nonpredator threat. Neuroscience and Biobehavioral Reviews 2005, 29:1243-1253.
5. Blanchard R.J., Yang M., Li C.I., Gervacio A., Blanchard D.C. Cue and context conditioning of defensive behaviors to cat odor stimuli. Neuroscience and Biobehavioral Reviews 2001, 25:587-595.
6. Campeau S., Nyhuis T.J., Sasse S.K., Day H.E.W., Masini C.V. Acute and chronic effects of ferret odor exposure in Sprague-Dawley rats. Neuroscience and Biobehavioral Reviews 2008, 32:1277-1286.
7. Clarin T., Sandhu S., Apfelbach R. Odor detection and odor discrimination in subadult and adult rats for two enantiomeric odorants supported by c-fos data. Behavioral Brain Research 2010, 206:229-235.
8. Collins D.R. Differential modulation of hippocampal plasticity in a non-noxious conflict model of anxiety. Neuroscience 2009, 162:963-969.
9. Dielenberg R.A., Hunt G.E., McGregor I.S. " When a rat smells a cat": the distribution of Fos immunoreactivity in rat brain following exposure to a predatory odor. Neuroscience 2001, 104:1085-1097.
10. Dielenberg R.A., McGregor I.S. Defensive behavior in rats towards predatory odors: A review. Neuroscience and Biobehavioral Reviews 2001, 25:597-609.
11. Fendt M., Endres T. 2,3,5-Trimethyl-3-thiazoline (TMT), a component of fox odor: just repugnant or really fear-inducing? Neuroscience and Biobehavioral Reviews 2008, 32:1259-1266.
12. Hubbard D.T., Blanchard D.C., Yang M., Markham C.M., Gervacio A., Chun-I L., Blanchard R.J. Development of defensive behavior and conditioning to cat odor in the rat. Physiology and Behavior 2004, 80:525-530.
13. Izquierdo I., Quillfeldt J.A., Zanatta M.S., Quevedo J., Schaeffer E., Schmitz P.K., Medina J.H. Sequential role of hippocampus and amygdala, entorhinal cortex and parietal cortex in formation and retrieval of memory for inhibitory avoidance in rats. European Journal of Neuroscience 1997, 9:786-793.
14. Martinez-Marcos A. On the organization of olfactory and vomeronasal cortices. Progress in Neurobiology 2009, 87:21-30.
15. Masini C.V., Garcia R.J., Sasse S.K., Nyhuis T.J., Day H.E.W., Campeau S. Accessory and main olfactory systems influences on predator odor-induced behavioral and endocrine stress responses in rats. Behavioral Brain Research 2010, 207:70-77.
16. McGregor I.S., Schrama L., Ambermoon P., Dielenberg R.A. Not all 'predator odors' are equal: Cat odor but not 2,4,5 trimethylthiazoline (TMT; fox odor) elicits specific defensive behaviors in rats. Behavioral Brain Research 2002, 129:1-16.
17. McKernan M.G., Shinnick-Gallagher P. Fear conditioning induces a lasting potentiation of synaptic currents in vitro. Nature 1997, 390:607-611.
18. Meredith M. Vomeronasal, olfactory, hormonal convergence in the brain. Cooperation or coincidence? Annals of the New York Academy of Sciences 1998, 855:349-361.
19. Meredith M., Westberry J.M. Distinctive responses in the medial amygdala to same-species and different-species pheromones. Journal of Neuroscience 2004, 24:5719-5725.
20. Otterson O.P. Afferent connections to the amygdaloid complex of the rat and cat: II. Afferents from the hypothalamus and the basal telencephalon. The Journal of Comparative Anatomy 1980, 194:267-289.
21. Pape H.C., Narayanan R.T., Smid J., Stork O., Seidenbecher T. Theta activity in neurons and networks of the amygdala related to long-term fear memory. Hippocampus 2005, 15:874-880.
22. Pape H.C., Paré D. Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear. Physiological reviews 2010, 90:419-463.
23. Paré D., Collins D.R. Neuronal correlates of fear in the lateral amygdala: Multiple extracellular recordings in conscious cats. Journal of Neuroscience 2000, 20:2701-2710.
24. Paxinos G., Watson C. The rat brain in stereotaxic coordinates 1998, Academic Press Ltd., London. 4th ed.
25. Pitkanen A., Savander V., LeDoux J.E. Organization of intra-amygdaloid circuitries in the rat: An emerging framework for understanding functions of the amygdala. Trends in Neurosciences 1997, 20:517-523.
26. Pro-Sistiaga P., Mohedano-Moriano A., Úbeda-bañón I., Del Mar Arroyo-Jiminaez M., Marcos P., Artacho-Pérula E., Crespo C., Insausti R., Martinez-Marcos A. Convergence of olfactory and vomeronasal projections in the rat basal telencephalon. The Journal of Comparative Anatomy 2007, 504:346-362.
27. Rodrigues S.M., Schafe G.E., LeDoux J.E. Molecular mechanisms underlying emotional learning and memory in the lateral amygdala. Neuron 2004, 44:75-91.
28. Rogan M.T., Stäubli U.V., LeDoux J.E. Fear conditioning induces associative long-term potentiation in the amygdala. Nature 1997, 390:604-607.
29. Rosen J.B., West E.A., Donley M.P. Not all rat strains are equal: Differential unconditioned fear responses to the synthetic fox odor 2,4,5-trimethylthiazoline in three outbred rat strains. Behavioral Neuroscience 2006, 120:290-297.
30. Rosenkrantz J.A., Grace A.A. Dopamine-mediated modulation of odor-evoked amygdala potentials during pavlovian conditioning. Nature 2002, 417:282-287.
31. Sah P., Westbrook R.F., Lüthi A. Fear conditioning and long-term potentiation in the amygdala: What really is the connection? Annals of the New York Academy of Sciences 2008, 1129:88-95.
32. Samuelsen C.L., Meredith M. Categorization of biologically relevant chemical signals in the medial amygdala. Brain Research 2009, 1263:33-42.
33. Schettino L.F., Otto T. Patterns of Fos expression in the amygdala and ventral perirhinal cortex induced by training in an olfactory fear conditioning paradigm. Behavioral Neuroscience 2001, 115:1257-1272.
34. Seidenbecher T., Laxmi T.R., Stork O., Pape H.C. Amygdalar and hippocampal theta rhythm synchronization during fear memory retrieval. Science 2003, 301:846-850.
35. Selden N.R., Everitt B.J., Jarrard L.E., Robbins T.W. Complementary roles for the amygdala and hippocampus in aversive conditioning to explicit and contextual cues. Neuroscience 1991, 42:335-350.
36. Sevelinges Y., Gervais R., Messaoudi B., Granjon L., Mouly A.M. Olfactory fear conditioning induces field potential potentiation in rat olfactory cortex and amygdala. Learning and Memory 2004, 11:761-769.
37. Staples L.G., McGregor I.S. Defensive responses of Wistar and Sprague-Dawley rats to cat odor and TMT. Behavioral Brain Research 2006, 172:351-354.
38. Staples L.G., McGregor I.S., Apfelbach R., Hunt G.E. Cat odor, but not trimethylthiazoline (fox odor), activates accessory olfactory and defense-related brain regions in rats. Neuroscience 2008, 151:937-947.
39. Takahashi L.K., Chan M.M., Pilar M.L. Predator odor fear conditioning: Current perspectives and new directions. Neuroscience and Biobehavioral Reviews 2008, 32:1218-1227.
40. Takahashi L.K., Nakashima B.R., Hong H., Watanabe K. The smell of danger: A behavioral and neural analysis of predator odor-induced fear. Neuroscience and Biobehavioral Reviews 2005, 29:1157-1167.
41. Tsvetkov E., Carlezon W.A., Benesm F.M., Kandel E.R., Bolshakov V.Y. Fear conditioning occludes LTP-induced presynaptic enhancement of synaptic transmission in the cortical pathway to the lateral amygdala. Neuron 2002, 34:289-300.
42. Winans S.S., Scalia F. Amygdaloid nucleus: New afferent input from the vomeronasal organ. Science 1970, 170:330-332.
43. Wong M., Chen Y., Moss R.L. Excitatory and inhibitory synaptic processing in the accessory olfactory system of the female rat. Neuroscience 1993, 56:355-365.
44. Xu L., Anwyl R., Rowan M.J. Behavioral stress facilitates the induction of long-term depression in the hippocampus. Nature 1997, 387:497-500.