The IL1RN promoter rs4251961 correlates with IL-1 receptor antagonist concentrations in human infection and is differentially regulated by GATA-1

Journal of Immunology

Volumn 186, Issue 4, 2011, Pages 2329-2335

  Carrol, Enitan D ^a,c,d   Payton, Antony ^b   Payne, Deborah ^b   Miyajima, Fabio ^c   Chaponda, Mas ^c   Mankhambo, Limangeni A ^a,d   Banda, Daniel L ^a   Molyneux, Elizabeth M ^d   Cox, Helen ^c   Jacobson, Greg ^c   Carr, Daniel F ^c   Molyneux, Malcolm E ^a   Stewart, James P ^c   Quinn, John P ^c   Hart, C Anthony ^c   Ollier, William E ^b  

^a MALAWI LIVERPOOL WELLCOME TRUST CLINICAL RESEARCH PROGRAMME   (Malawi)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d UNIVERSITY OF MALAWI   (Malawi)

Author keywords

[No Author keywords available]

Indexed keywords

GLOBIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TRANSCRIPTION FACTOR GATA 1;

ALLELE; ARTICLE; CHILD; COHORT ANALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE SEVERITY; EMBRYO; FEMALE; GENE CONSTRUCT; GENETIC TRANSFECTION; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; INVASIVE PNEUMOCOCCAL DISEASE; MAJOR CLINICAL STUDY; MALE; PATHOPHYSIOLOGY; PLASMID; PNEUMOCOCCAL INFECTION; PRESCHOOL CHILD; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVOR;

ADULT; ALLELES; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; GATA1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, BACTERIAL; HEK293 CELLS; HUMANS; INFANT; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; MALE; MENINGITIS, PNEUMOCOCCAL; PNEUMONIA, PNEUMOCOCCAL; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; YOUNG ADULT;

EID: 79951828169     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002402     Document Type: Article

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