Variant mannose-binding lectin alleles are not associated with susceptibility to or outcome of invasive pneumococcal infection in randomly included patients

Journal of Infectious Diseases

Volumn 185, Issue 10, 2002, Pages 1517-1520

  Kronborg, Gitte ^a   Weis, Nina ^b   Madsen, Hans O ^a   Pedersen, Svend S ^c   Wejse, Christian ^d   Nielsen, Henrik ^e   Skinhøj, Peter ^a   Garred, Peter ^a  

^a International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^b HVIDOVRE HOSPITAL   (Denmark)

^c ODENSE UNIVERSITY HOSPITAL   (Denmark)

^d AARHUS UNIVERSITY HOSPITAL   (Denmark)

^e AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

LECTIN; MANNOSE BINDING LECTIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOMES RESEARCH; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; BACTEREMIA; CARRIER PROTEINS; COLLECTINS; DENMARK; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HOSPITALS; HUMANS; LECTINS; MALE; MIDDLE AGED; PNEUMOCOCCAL INFECTIONS; PROSPECTIVE STUDIES; STREPTOCOCCUS PNEUMONIAE; VARIATION (GENETICS);

EID: 0037094086     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/340216     Document Type: Article

References (15)

1. Acute respiratory infections and mannose-binding lectin insufficiency during early childhood
2. Increased frequency of homozygosity of abnormal mannan-binding-protein alleles in patients with suspected immunodeficiency
3. Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis
4. Association of mutations in mannose binding protein gene with childhood infections in consecutive hospital series
5. Association of variants of the gene for mannose-binding lectin with susceptibility to meningococcal disease
6. Invasive pneumococcal disease in England and Wales: Vaccination implications
7. Bacteremia with Streptococcus pneumonia: Implications for therapy and prevention
8. Mannose-binding lectin: Structure, function, genetics and disease associations
9. Mannose-binding lectin polymorphisms and susceptibility to infection in systemic lupus erythematosus
10. Different molecular events result in low protein levels of mannan-binding lectin in populations from Southeast Africa and South America
11. Susceptibility to HIV infection and progression to AIDS in relation to variant alleles of mannose-binding lectin
12. Mannose-binding lectin binds to a range of clinically relevant microorganisms and promotes complement deposition
13. Differential binding of mannose-binding lectin to respiratory pathogens in cystic fibrosis
14. Prospective study of prognostic factors in community-acquired bacteremic pneumococcal disease in 5 countries
15. Cigarette smoking and invasive pneumococcal disease