-
1
-
-
9244239811
-
G 1 cell-cycle control and cancer
-
Massague J: G 1 cell-cycle control and cancer. Nature 2004; 432: 298-306.
-
(2004)
Nature
, vol.432
, pp. 298-306
-
-
Massague, J.1
-
2
-
-
0032981481
-
Induced expression of p16(INK4α) inhibits both CDK4- and CDK2- associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes
-
McConnell BB, Gregory FJ, Stott FJ, Hara E, Peters G: Induced expression of p16 INK4a inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin- CDK-inhibitor complexes. Mol Cell Biol 1999; 19: 1981-1989. (Pubitemid 29098256)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.3
, pp. 1981-1989
-
-
McConnell, B.B.1
Gregory, F.J.2
Stott, F.J.3
Hara, E.4
Peters, G.5
-
3
-
-
0031842101
-
Requirement of cyclin E-Cdk2 inhibition in p16(INK4α)-mediated growth suppression
-
Jiang H, Chou HS, Zhu L: Requirement of cyclin E-Cdk2 inhibition in p16 INK4a -mediated growth suppression. Mol Cell Biol 1998; 18: 5284-5290. (Pubitemid 28388112)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.9
, pp. 5284-5290
-
-
Jiang, H.1
Chou, H.S.2
Zhu, L.3
-
4
-
-
1242342071
-
Retinoblastoma protein in human renal cell carcinoma in relation to alterations in G1/S regulatory proteins
-
DOI 10.1002/ijc.11665
-
Hedberg Y, Ljungberg B, Roos G, Landberg G: Retinoblastoma protein in human renal cell carcinoma in relation to alterations in G 1 /S regulatory proteins. Int J Cancer 2004; 109: 189-193. (Pubitemid 38240919)
-
(2004)
International Journal of Cancer
, vol.109
, Issue.2
, pp. 189-193
-
-
Hedberg, Y.1
Ljungberg, B.2
Roos, G.3
Landberg, G.4
-
5
-
-
0032505753
-
Regulation of expression and activity of distinct pRB, E2F, D-type cyclin, and CKI family members during terminal differentiation of P19 cells
-
DOI 10.1006/excr.1998.4197
-
Gill RM, Slack R, Kiess M, Hamel PA: Regulation of expression and activity of distinct pRb, E2F, D-type cyclin, and CKI family members during terminal differentiation of p19 cells. Exp Cell Res 1998; 244: 157-170. (Pubitemid 28480864)
-
(1998)
Experimental Cell Research
, vol.244
, Issue.1
, pp. 157-170
-
-
Gill, R.M.1
Slack, R.2
Kiess, M.3
Hamel, P.A.4
-
6
-
-
0345167184
-
INK4A pathway in endometrial carcinogenesis
-
DOI 10.1016/j.canlet.2003.09.012
-
Semczuk A, Jakowicki JA: Alterations of pRb1-cyclin D1-cdk4/6-p16 INK4A pathway in endometrial carcinogenesis. Cancer Lett 2004; 203: 1-12. (Pubitemid 37506078)
-
(2004)
Cancer Letters
, vol.203
, Issue.1
, pp. 1-12
-
-
Semczuk, A.1
Jakowicki, J.A.2
-
7
-
-
33751293168
-
Retinoblastoma pathway defects show differential ability to activate the constitutive DNA damage response in human tumorigenesis
-
DOI 10.1158/0008-5472.CAN-06-2178
-
Tort F, Bartkova J, Sehested M, Orntoft T, Lukas J, Bartek J: Retinoblastoma pathway defects show differential ability to activate the constitutive DNA damage response in human tumorigenesis. Cancer Res 2006; 66: 10258-10263. (Pubitemid 44799741)
-
(2006)
Cancer Research
, vol.66
, Issue.21
, pp. 10258-10263
-
-
Tort, F.1
Bartkova, J.2
Sehested, M.3
Oorntoft, T.4
Lukas, J.5
Bartek, J.6
-
8
-
-
3142606708
-
ARF, in human reference urothelium and bladder carcinomas, according to pRb and p53 protein status
-
DOI 10.1016/j.humpath.2004.01.019, PII S0046817704000735
-
le Frère-Belda MA, Gil Diez de Medina S, Daher A, Martin N, Albaud B, Heudes D, Abbou CC, Thiery JP, Zafrani ES, Radvanyi F, Chopin D: Profiles of the 2 INK4a gene products, p16 and p14 ARF , in human reference urothelium and bladder carcinomas, according to pRb and p53 protein status. Hum Pathol 2004; 35: 817-824. (Pubitemid 38903074)
-
(2004)
Human Pathology
, vol.35
, Issue.7
, pp. 817-824
-
-
Le Frere-Belda, M.-A.1
Gil Diez De Medina, S.2
Daher, A.3
Martin, N.4
Albaud, B.5
Heudes, D.6
Abbou, C.C.7
Thiery, J.P.8
Zafrani, E.S.9
Radvanyi, F.10
Chopin, D.11
-
9
-
-
4644324676
-
INK4a in cell defenses against transformation
-
Drayton S, Brookes S, Rowe J, Peters G: The significance of p16INK4a in cell defenses against transformation. Cell Cycle 2004; 3: 611-615. (Pubitemid 40278203)
-
(2004)
Cell Cycle
, vol.3
, Issue.5
, pp. 611-615
-
-
Drayton, S.1
Brookes, S.2
Rowe, J.3
Peters, G.4
-
10
-
-
0032786446
-
Alterations of expression of Rb, p16(INK4A) and cyclin D1 in non-small cell lung carcinoma and their clinical significance
-
DOI 10.1002/(SICI)1096-9896(199 908)188:4<351::AID-PATH385>3.0. CO;2-W
-
Brambilla E, Moro D, Gazzeri S, Brambilla C: Alterations of expression of Rb, p16 INK4A and cyclin D1 in non-small cell lung carcinoma and their clinical significance. J Pathol 1999; 188: 351-360. (Pubitemid 29327432)
-
(1999)
Journal of Pathology
, vol.188
, Issue.4
, pp. 351-360
-
-
Brambilla, E.1
Moro, D.2
Gazzeri, S.3
Brambilla, C.4
-
11
-
-
0032935233
-
Changes in expression of pRb, p16 and cyclin D1 in non-small cell lung cancer: An immunohistochemical study
-
Malusecka E, Zborek A, Krzyzowska-Gruca S: Changes in expression of pRb, p16 and cyclin D1 in non-small cell lung cancer: an immunohistochemical study. Folia Histochem Cytobiol 1999; 37: 19-24. (Pubitemid 29067625)
-
(1999)
Folia Histochemica et Cytobiologica
, vol.37
, Issue.1
, pp. 19-24
-
-
Malusecka, E.1
Zborek, A.2
Krzyzowska-Gruca, S.3
-
12
-
-
58149316237
-
Relationship of phospho- pRb (Ser-807/811) level to exposure to tobacco smoke in primary non-small cell lung cancer
-
Ko E, Kim Y, Lee BB, Han J, Song SY, Shim YM, Park J, Kim DH: Relationship of phospho- pRb (Ser-807/811) level to exposure to tobacco smoke in primary non-small cell lung cancer. Cancer Lett 2009; 274: 225-232.
-
(2009)
Cancer Lett
, vol.274
, pp. 225-232
-
-
Ko, E.1
Kim, Y.2
Lee, B.B.3
Han, J.4
Song, S.Y.5
Shim, Y.M.6
Park, J.7
Kim, D.H.8
-
13
-
-
0036890048
-
INK4A and retinoblastoma proteins in non-small-cell lung carcinoma
-
DOI 10.1016/S0169-5002(02)00301-X, PII S016950020200301X
-
Akin H, Yilmazbayhan D, Kiliçaslan Z, Dilege S, Doǧan O, Toker A, Kalayci G: Clinical significance of p16 INK4A and retinoblastoma proteins in non-small-cell lung carcinoma. Lung Cancer 2002; 38: 253-260. (Pubitemid 35341799)
-
(2002)
Lung Cancer
, vol.38
, Issue.3
, pp. 253-260
-
-
Akin, H.1
Yilmazbayhan, D.2
Kilicaslan, Z.3
Dilege, S.4
Dogan, O.5
Toker, A.6
Kalayci, G.7
-
14
-
-
0032849595
-
Expression of p16 and lack of pRB in primary small cell lung cancer
-
DOI 10.1002/(SICI)1096-9896(199 911)189:3<358::AID-PATH452>3.0. CO;2-1
-
Yuan J, Knorr J, Altmannsberger M, Goeckenjan G, Ahr A, Scharl A, Strebhardt K: Expression of p16 and lack of pRB in primary small cell lung cancer. J Pathol 1999; 189: 358-362. (Pubitemid 29489220)
-
(1999)
Journal of Pathology
, vol.189
, Issue.3
, pp. 358-362
-
-
Yuan, J.1
Knorr, J.2
Altmannsberger, M.3
Goeckenjan, G.4
Ahr, A.5
Scharl, A.6
Strebhardt, K.7
-
15
-
-
34250210567
-
Prognostic implications of cell cycle-related proteins in primary resectable pathologic N2 nonsmall cell lung cancer
-
DOI 10.1002/cncr.22651
-
Mohamed S, Yasufuku K, Hiroshima K, Nakajima T, Yoshida S, Suzuki M, Sekine Y, Shibuya K, Iizasa T, Farouk A, Fujisawa T: Prognostic implications of cell cycle-related proteins in primary resectable pathologic N2 nonsmall cell lung cancer. Cancer 2007; 109: 2506-2514. (Pubitemid 46906470)
-
(2007)
Cancer
, vol.109
, Issue.12
, pp. 2506-2514
-
-
Mohamed, S.1
Yasufuku, K.2
Hiroshima, K.3
Nakajima, T.4
Yoshida, S.5
Suzuki, M.6
Sekine, Y.7
Shibuya, K.8
Lizasa, T.9
Farouk, A.10
Fujisawa, T.11
-
16
-
-
33846224772
-
P16INK4a expression and clinicopathologic parameters in renal cell carcinoma
-
Ikuerowo SO, Kuczyk MA, von Wasielewski R, Shittu OB, Jonas U, Machtens S, Serth J: p16INK4a expression and clinicopathologic parameters in renal cell carcinoma. Eur Urol 2007; 51: 732-737.
-
(2007)
Eur Urol
, vol.51
, pp. 732-737
-
-
Ikuerowo, S.O.1
Kuczyk, M.A.2
Von Wasielewski, R.3
Shittu, O.B.4
Jonas, U.5
MacHtens, S.6
Serth, J.7
-
17
-
-
0028949020
-
Expression of tumour-suppressor gene Rb, apoptosis-suppressing protein Bcl-2 and c-Myc have no independent prognostic value in renal adenocarcinoma
-
Lipponen P, Eskelinen M, Syrjänen K: Expression of tumour-suppressor gene Rb, apoptosis-suppressing protein Bcl-2 and c-Myc have no independent prognostic value in renal adenocarcinoma. Br J Cancer 1995; 71: 863-867.
-
(1995)
Br J Cancer
, vol.71
, pp. 863-867
-
-
Lipponen, P.1
Eskelinen, M.2
Syrjänen, K.3
-
18
-
-
0029026742
-
Loss of heterozygosity occurs centromeric to RB without associated abnormalities in the retinoblastoma gene in tumors from patients with metastatic renal cell carcinoma
-
Walther MM, Gnarra JR, Elwood L, Xu HJ, Florence C, Anglard P, Hu SX, King C, Trahan E, Hurley K, et al: Loss of heterozygosity occurs centromeric to RB without associated abnormalities in the retinoblastoma gene in tumors from patients with metastatic renal cell carcinoma. J Urol 1995; 153: 2050-2054.
-
(1995)
J Urol
, vol.153
, pp. 2050-2054
-
-
Walther, M.M.1
Gnarra, J.R.2
Elwood, L.3
Xu, H.J.4
Florence, C.5
Anglard, P.6
Hu, S.X.7
King, C.8
Trahan, E.9
Hurley, K.10
-
19
-
-
0034865174
-
Expression of the cell cycle proteins P21, P27, and PRB in clear cell renal cell carcinoma and their prognostic significance
-
DOI 10.1016/S0090-4295(01)01188-8, PII S0090429501011888
-
Haitel A, Wiener HG, Neudert B, Marberger M, Susani M: Expression of the cell cycle proteins p21, p27, and pRb in clear cell renal cell carcinoma and their prognostic significance. Urology 2001; 58: 477-481. (Pubitemid 32816374)
-
(2001)
Urology
, vol.58
, Issue.3
, pp. 477-481
-
-
Haitel, A.1
Wiener, H.G.2
Neudert, B.3
Marberger, M.4
Susani, M.5
-
20
-
-
0029942347
-
Expression of the retinoblastoma gene product in renal tumors
-
Presti JC Jr, Reuter VE, Cordon-Cardo C, Motzer RJ, Albino AP, Jhanwar SC, Nanus DM: Expression of the retinoblastoma gene product in renal tumors. Anticancer Res 1996; 16: 549-556. (Pubitemid 26181980)
-
(1996)
Anticancer Research
, vol.16
, Issue.2
, pp. 549-556
-
-
Presti Jr., J.C.1
Reuter, V.E.2
Cordon-Cardo, C.3
Motzer, R.J.4
Albino, A.P.5
Jhanwar, S.C.6
Nanus, D.M.7
-
21
-
-
0025883860
-
Lack of nuclear RB protein staining in G0/middle G1 cells: Correlation to changes in total RB protein level
-
Xu HJ, Hu SX, Benedict WF: Lack of nuclear RB protein staining in G 0 /middle G 1 cells: correlation to changes in total RB protein level. Oncogene 1991; 6: 1139-1146. (Pubitemid 21924200)
-
(1991)
Oncogene
, vol.6
, Issue.7
, pp. 1139-1146
-
-
Xu, H.-J.1
Hu, S.-X.2
Benedict, W.F.3
-
22
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman JG, Merlo A, Mao L, Lapidus RG, Issa JP, Davidson NE, Sidransky D, Baylin SB: Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 1995; 55: 4525-4530.
-
(1995)
Cancer Res
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
Lapidus, R.G.4
Issa, J.P.5
Davidson, N.E.6
Sidransky, D.7
Baylin, S.B.8
-
23
-
-
0026653420
-
The essentials of DNA methylation
-
Bird A: The essentials of DNA methylation. Cell 1992; 70: 5-8.
-
(1992)
Cell
, vol.70
, pp. 5-8
-
-
Bird, A.1
-
24
-
-
0029011539
-
5′CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB, Sidransky D: 5′CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995; 1: 686-692.
-
(1995)
Nat Med
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
25
-
-
0035670518
-
INK4a genes renal cell carcinomas
-
Kawada Y, Nakamura M, Ishida E, Shimada K, Oosterwijk E, Uemura H, Hirao Y, Chul KS, Konishi N: Aberrations of the p14 ARF and p16 INK4a genes in renal cell carcinomas. Jpn J Cancer Res 2001; 92: 1293-1299. (Pubitemid 34036892)
-
(2001)
Japanese Journal of Cancer Research
, vol.92
, Issue.12
, pp. 1293-1299
-
-
Kawada, Y.1
Nakamura, M.2
Ishida, E.3
Shimada, K.4
Oosterwijk, E.5
Uemura, H.6
Hirao, Y.7
Chul, K.S.8
Konishi, N.9
-
26
-
-
33751369174
-
Human papillomavirus DNA and P16INK4A are not detected in renal tumors with immunohistochemistry and signal-amplified in situ hybridization in paraffin-embedded tissue
-
DOI 10.1097/01.pai.0000205059.42421.cb, PII 0012903920061200000011
-
Hodges A, Talley L, Gokden N: Human papillomavirus DNA and P16 INK4A are not detected in renal tumors with immunohistochemistry and signal-amplified in situ hybridization in paraffin-embedded tissue. Appl Immunohistochem Mol Morphol 2006; 14: 432-435. (Pubitemid 44813704)
-
(2006)
Applied Immunohistochemistry and Molecular Morphology
, vol.14
, Issue.4
, pp. 432-435
-
-
Hodges, A.1
Talley, L.2
Gokden, N.3
-
27
-
-
42949122614
-
Inactivation of p16 by CpG hypermethylation in renal cell carcinoma
-
DOI 10.1016/j.urolonc.2007.01.018, PII S1078143907000270
-
Vidaurreta M, Maestro ML, Sanz-Casla MT, Maestro C, Rafael S, Veganzones S, Moreno J, Blanco J, Silmi A, Arroyo M: Inactivation of p16 by CpG hypermethylation in renal cell carcinoma. Urol Oncol 2008; 26: 239-245. (Pubitemid 351608573)
-
(2008)
Urologic Oncology: Seminars and Original Investigations
, vol.26
, Issue.3
, pp. 239-245
-
-
Vidaurreta, M.1
Maestro, M.L.2
Sanz-Casla, M.T.3
Maestro, C.4
Rafael, S.5
Veganzones, S.6
Moreno, J.7
Blanco, J.8
Silmi, A.9
Arroyo, M.10
-
28
-
-
0042564565
-
Loss of heterozygosity and methylation of p16 in renal cell carcinoma
-
DOI 10.1007/s00240-003-0308-3
-
Sanz-Casla MT, Maestro ML, del Barco V, Zanna I, Moreno J, Vidaurreta M, Almansa I, Fernández C, Blanco J, Maestro C, Resel L: Loss of heterozygosity and methylation of p16 in renal cell carcinoma. Urol Res 2003; 31: 159-162. (Pubitemid 36962022)
-
(2003)
Urological Research
, vol.31
, Issue.3
, pp. 159-162
-
-
Sanz-Casla, M.T.1
Maestro, M.L.2
Del Barco, V.3
Zanna, I.4
Moreno, J.5
Vidaurreta, M.6
Almansa, I.7
Fernandez, C.8
Blanco, J.9
Maestro, C.10
Resel, L.11
-
29
-
-
0035187023
-
ARF cell cycle regulatory pathways in primary neuroblastoma: P16 expression is associated with advanced stage disease
-
Omura-Minamisawa M, Diccianni MB, Chang RC, Batova A, Bridgeman LJ, Schiff J, Cohn SL, London WB, Yu AL: p16/p14 ARF cell cycle regulatory pathways in primary neuroblastoma: p16 expression is associated with advanced stage disease. Clin Cancer Res 2001; 7: 3481-3490. (Pubitemid 33069984)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.11
, pp. 3481-3490
-
-
Omura-Minamisawa, M.1
Diccianni, M.B.2
Chang, R.C.3
Batova, A.4
Bridgeman, L.J.5
Schiff, J.6
Cohn, S.L.7
London, W.B.8
Yu, A.L.9
-
31
-
-
38949096774
-
Alterations found in p16/Rb/cyclin D1 pathway in the dysplastic and malignant cervical epithelium
-
DOI 10.3727/096504007783438367
-
Vijayalakshmi N, Selvaluxmi G, Majhi U, Rajkumar T: Alterations found in p16/Rb/cyclin D1 pathway in the dysplastic and malignant cervical epithelium. Oncol Res 2007; 16: 527-533. (Pubitemid 351211325)
-
(2007)
Oncology Research
, vol.16
, Issue.11
, pp. 527-533
-
-
Vijayalakshmi, N.1
Selvaluxmi, G.2
Majhi, U.3
Rajkumar, T.4
-
33
-
-
54049096336
-
Alterations in the p16 INK4a /cyclin D1/RB pathway in gastrointestinal tract endocrine tumors
-
Li AF, Li AC, Tsay SH, Li WY, Liang WY, Chen JY: Alterations in the p16 INK4a /cyclin D1/RB pathway in gastrointestinal tract endocrine tumors. Am J Clin Pathol 2008; 130: 535-542.
-
(2008)
Am J Clin Pathol
, vol.130
, pp. 535-542
-
-
Li, A.F.1
Li, A.C.2
Tsay, S.H.3
Li, W.Y.4
Liang, W.Y.5
Chen, J.Y.6
-
34
-
-
55149101963
-
Current status of prognostic immunohistochemical markers for urothelial bladder cancer
-
Rosenblatt R, Jonmarker S, Lewensohn R, Egevad L, Sherif A, Kälkner KM, Nilsson S, Valdman A, Ullén A: Current status of prognostic immunohistochemical markers for urothelial bladder cancer. Tumour Biol 2008; 29: 311-322.
-
(2008)
Tumour Biol
, vol.29
, pp. 311-322
-
-
Rosenblatt, R.1
Jonmarker, S.2
Lewensohn, R.3
Egevad, L.4
Sherif, A.5
Kälkner, K.M.6
Nilsson, S.7
Valdman, A.8
Ullén, A.9
-
35
-
-
53549099376
-
Histologic and epidemiologic correlates of P-MAPK, Brn-2, pRb, p53, and p16 immunostaining in cutaneous melanomas
-
Richmond-Sinclair NM, Lee E, Cummings MC, Williamson R, Muller K, Green AC, Hayward NK, Whiteman DC: Histologic and epidemiologic correlates of P-MAPK, Brn-2, pRb, p53, and p16 immunostaining in cutaneous melanomas. Melanoma Res 2008; 18: 336-345.
-
(2008)
Melanoma Res
, vol.18
, pp. 336-345
-
-
Richmond-Sinclair, N.M.1
Lee, E.2
Cummings, M.C.3
Williamson, R.4
Muller, K.5
Green, A.C.6
Hayward, N.K.7
Whiteman, D.C.8
|