-
1
-
-
77949910265
-
Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration
-
Gendron TF, Josephs KA, Petrucelli L. Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration. Neuropathol Appl Neurobiol 2010; 36: 97-124
-
(2010)
Neuropathol Appl Neurobiol
, vol.36
, pp. 97-124
-
-
Gendron, T.F.1
Josephs, K.A.2
Petrucelli, L.3
-
3
-
-
47949131497
-
Frontotemporal lobar degeneration with ubiquitin-positive, but TDP-43-negative inclusions
-
Josephs KA, Lin WL, Ahmed Z, Stroh DA, Graff-Radford NR, Dickson DW. Frontotemporal lobar degeneration with ubiquitin-positive, but TDP-43-negative inclusions. Acta Neuropathol 2008; 116: 159-67
-
(2008)
Acta Neuropathol
, vol.116
, pp. 159-167
-
-
Josephs, K.A.1
Lin, W.L.2
Ahmed, Z.3
Stroh, D.A.4
Graff-Radford, N.R.5
Dickson, D.W.6
-
4
-
-
47949123961
-
TDP-43-negative FTLD-U is a significant new clinico-pathological subtype of FTLD
-
Roeber S, Mackenzie IR, Kretzschmar HA, Neumann M. TDP-43-negative FTLD-U is a significant new clinico-pathological subtype of FTLD. Acta Neuropathol 2008; 116: 147-57
-
(2008)
Acta Neuropathol
, vol.116
, pp. 147-157
-
-
Roeber, S.1
Mackenzie, I.R.2
Kretzschmar, H.A.3
Neumann, M.4
-
5
-
-
34249949338
-
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
-
Amador-Ortiz C, Lin WL, Ahmed Z, Personett D, Davies P, Duara R, Graff-Radford NR, Hutton ML, Dickson DW. TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann Neurol 2007; 61: 435-45
-
(2007)
Ann Neurol
, vol.61
, pp. 435-445
-
-
Amador-Ortiz, C.1
Lin, W.L.2
Ahmed, Z.3
Personett, D.4
Davies, P.5
Duara, R.6
Graff-Radford, N.R.7
Hutton, M.L.8
Dickson, D.W.9
-
6
-
-
59249097160
-
Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies
-
Arai T, Mackenzie IR, Hasegawa M, Nonoka T, Niizato K, Tsuchiya K, Iritani S, Onaya M, Akiyama H. Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies. Acta Neuropathol 2009; 117: 125-36
-
(2009)
Acta Neuropathol
, vol.117
, pp. 125-136
-
-
Arai, T.1
Mackenzie, I.R.2
Hasegawa, M.3
Nonoka, T.4
Niizato, K.5
Tsuchiya, K.6
Iritani, S.7
Onaya, M.8
Akiyama, H.9
-
7
-
-
73549109864
-
Transactive response DNA-binding protein 43 burden in familial Alzheimer disease and Down syndrome
-
Lippa CF, Rosso AL, Stutzbach LD, Neumann M, Lee VM, Trojanowski JQ. Transactive response DNA-binding protein 43 burden in familial Alzheimer disease and Down syndrome. Arch Neurol 2009; 66: 1483-8
-
(2009)
Arch Neurol
, vol.66
, pp. 1483-1488
-
-
Lippa, C.F.1
Rosso, A.L.2
Stutzbach, L.D.3
Neumann, M.4
Lee, V.M.5
Trojanowski, J.Q.6
-
8
-
-
36348972414
-
Concurrence of TDP-43, tau and alpha-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies
-
Higashi S, Iseki E, Yamamoto R, Minegishi M, Hino H, Fujisawa K, Togo T, Katsuse O, Uchikado H, Furukawa Y, Kosaka K, Arai H. Concurrence of TDP-43, tau and alpha-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies. Brain Res 2007; 1184: 284-94
-
(2007)
Brain Res
, vol.1184
, pp. 284-294
-
-
Higashi, S.1
Iseki, E.2
Yamamoto, R.3
Minegishi, M.4
Hino, H.5
Fujisawa, K.6
Togo, T.7
Katsuse, O.8
Uchikado, H.9
Furukawa, Y.10
Kosaka, K.11
Arai, H.12
-
9
-
-
66149114101
-
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
-
Zhang YJ, Xu YF, Cook C, Gendron TF, Roettges P, Link CD, Lin WL, Tong J, Castanedes-Casey M, Ash P, Gass J, Rangachari V, Buratti E, Baralle F, Golde TE, Dickson DW, Petrucelli L. Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc Natl Acad Sci USA 2009; 106: 7607-12
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7607-7612
-
-
Zhang, Y.J.1
Xu, Y.F.2
Cook, C.3
Gendron, T.F.4
Roettges, P.5
Link, C.D.6
Lin, W.L.7
Tong, J.8
Castanedes-Casey, M.9
Ash, P.10
Gass, J.11
Rangachari, V.12
Buratti, E.13
Baralle, F.14
Golde, T.E.15
Dickson, D.W.16
Petrucelli, L.17
-
10
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, Bruce J, Schuck T, Grossman M, Clark CM, McCluskey LF, Miller BL, Masliah E, Mackenzie IR, Feldman H, Feiden W, Kretzschmar HA, Trojanowski JQ, Lee VMY. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006; 314: 130-3
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.Y.19
-
11
-
-
0035919837
-
Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies
-
Kuusisto E, Salminen A, Alafuzoff I. Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies. Neuroreport 2001; 12: 2085-90
-
(2001)
Neuroreport
, vol.12
, pp. 2085-2090
-
-
Kuusisto, E.1
Salminen, A.2
Alafuzoff, I.3
-
12
-
-
0036284021
-
Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: possible role in tangle formation
-
Kuusisto E, Salminen A, Alafuzoff I. Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: possible role in tangle formation. Neuropathol Appl Neurobiol 2002; 28: 228-37
-
(2002)
Neuropathol Appl Neurobiol
, vol.28
, pp. 228-237
-
-
Kuusisto, E.1
Salminen, A.2
Alafuzoff, I.3
-
14
-
-
45249105920
-
Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration
-
Babu JR, Lamar Seibenhener M, Peng J, Strom AL, Kemppainen R, Cox N, Zhu H, Wooten MC, Diaz-Meco MT, Moscat J, Wooten MW. Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration. J Neurochem 2008; 106: 107-20
-
(2008)
J Neurochem
, vol.106
, pp. 107-120
-
-
Babu, J.R.1
Lamar Seibenhener, M.2
Peng, J.3
Strom, A.L.4
Kemppainen, R.5
Cox, N.6
Zhu, H.7
Wooten, M.C.8
Diaz-Meco, M.T.9
Moscat, J.10
Wooten, M.W.11
-
15
-
-
56749104288
-
Inclusion-body myositis: muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer's and Parkinson's disease brains
-
Askanas V, Engel WK. Inclusion-body myositis: muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer's and Parkinson's disease brains. Acta Neuropathol 2008; 116: 583-95
-
(2008)
Acta Neuropathol
, vol.116
, pp. 583-595
-
-
Askanas, V.1
Engel, W.K.2
-
16
-
-
66949145779
-
Inclusion body myositis: a degenerative muscle disease associated with intra-muscle fiber multi-protein aggregates, proteasome inhibition, endoplasmic reticulum stress and decreased lysosomal degradation
-
Askanas V, Engel WK, Nogalska A. Inclusion body myositis: a degenerative muscle disease associated with intra-muscle fiber multi-protein aggregates, proteasome inhibition, endoplasmic reticulum stress and decreased lysosomal degradation. Brain Pathol 2009; 19: 493-506
-
(2009)
Brain Pathol
, vol.19
, pp. 493-506
-
-
Askanas, V.1
Engel, W.K.2
Nogalska, A.3
-
17
-
-
33746530058
-
Sporadic inclusion body myositis - diagnosis, pathogenesis and therapeutic strategies
-
Dalakas MC. Sporadic inclusion body myositis - diagnosis, pathogenesis and therapeutic strategies. Nat Clin Pract Neurol 2006; 2: 437-47
-
(2006)
Nat Clin Pract Neurol
, vol.2
, pp. 437-447
-
-
Dalakas, M.C.1
-
18
-
-
68349097450
-
p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis
-
Nogalska A, Terracciano C, D'Agostino C, Engel WK, Askanas V. p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis. Acta Neuropathol 2009; 118: 407-13
-
(2009)
Acta Neuropathol
, vol.118
, pp. 407-413
-
-
Nogalska, A.1
Terracciano, C.2
D'Agostino, C.3
Engel, W.K.4
Askanas, V.5
-
19
-
-
53149138951
-
TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia
-
Weihl CC, Temiz P, Miller SE, Watts G, Smith C, Forman M, Hanson PI, Kimonis V, Pestronk A. TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia. J Neurol Neurosurg Psychiatry 2008; 79: 1186-9
-
(2008)
J Neurol Neurosurg Psychiatry
, vol.79
, pp. 1186-1189
-
-
Weihl, C.C.1
Temiz, P.2
Miller, S.E.3
Watts, G.4
Smith, C.5
Forman, M.6
Hanson, P.I.7
Kimonis, V.8
Pestronk, A.9
-
20
-
-
59249094498
-
TDP-43 accumulation is common in myopathies with rimmed vacuoles
-
Küsters B, van Hoeve BJ, Schelhaas HJ, Ter Laak H, van Engelen BG, Lammens M. TDP-43 accumulation is common in myopathies with rimmed vacuoles. Acta Neuropathol 2009; 117: 209-11
-
(2009)
Acta Neuropathol
, vol.117
, pp. 209-211
-
-
Küsters, B.1
van Hoeve, B.J.2
Schelhaas, H.J.3
Ter Laak, H.4
van Engelen, B.G.5
Lammens, M.6
-
21
-
-
65349175153
-
TAR DNA-Binding protein 43 accumulation in protein aggregate myopathies
-
Olivé M, Janué A, Moreno D, Gámez J, Torrejón-Escribano B, Ferrer I. TAR DNA-Binding protein 43 accumulation in protein aggregate myopathies. J Neuropathol Exp Neurol 2009; 68: 262-73
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 262-273
-
-
Olivé, M.1
Janué, A.2
Moreno, D.3
Gámez, J.4
Torrejón-Escribano, B.5
Ferrer, I.6
-
22
-
-
67650264666
-
Sarcoplasmic redistribution of nuclear TDP-43 in inclusion body myositis
-
Salajegheh M, Pinkus JL, Taylor JP, Amato AA, Nazareno R, Baloh RH, Greenberg SA. Sarcoplasmic redistribution of nuclear TDP-43 in inclusion body myositis. Muscle Nerve 2009; 40: 19-31
-
(2009)
Muscle Nerve
, vol.40
, pp. 19-31
-
-
Salajegheh, M.1
Pinkus, J.L.2
Taylor, J.P.3
Amato, A.A.4
Nazareno, R.5
Baloh, R.H.6
Greenberg, S.A.7
-
23
-
-
24144489814
-
Proteasome inhibition and aggresome formation in sporadic inclusion-body myositis and in amyloid-beta precursor protein-overexpressing cultured human muscle fibers
-
Fratta P, Engel WK, McFerrin J, Davies KJ, Lin SW, Askanas V. Proteasome inhibition and aggresome formation in sporadic inclusion-body myositis and in amyloid-beta precursor protein-overexpressing cultured human muscle fibers. Am J Pathol 2005; 167: 517-26
-
(2005)
Am J Pathol
, vol.167
, pp. 517-526
-
-
Fratta, P.1
Engel, W.K.2
McFerrin, J.3
Davies, K.J.4
Lin, S.W.5
Askanas, V.6
-
24
-
-
77956498664
-
Impaired autophagy in sporadic inclusion-body myositis and in endoplasmic reticulum stress-provoked cultured human muscle fibers
-
doi: 10.2353/ajpath.2010.100050
-
Nogalska A, D'Agostino C, Terracciano C, Engel WK, Askanas V. Impaired autophagy in sporadic inclusion-body myositis and in endoplasmic reticulum stress-provoked cultured human muscle fibers. Am J Pathol 2010; 177; doi: 10.2353/ajpath.2010.100050
-
(2010)
Am J Pathol
, vol.177
-
-
Nogalska, A.1
D'Agostino, C.2
Terracciano, C.3
Engel, W.K.4
Askanas, V.5
-
25
-
-
38149099865
-
Expression of mutant ubiquitin (UBB+1) and p62 in myotilinopathies and desminopathies
-
Olivé M, van Leeuwen FW, Janué A, Moreno D, Torrejón-Escribano B, Ferrer I. Expression of mutant ubiquitin (UBB+1) and p62 in myotilinopathies and desminopathies. Neuropathol Appl Neurobiol 2008; 34: 76-87
-
(2008)
Neuropathol Appl Neurobiol
, vol.34
, pp. 76-87
-
-
Olivé, M.1
van Leeuwen, F.W.2
Janué, A.3
Moreno, D.4
Torrejón-Escribano, B.5
Ferrer, I.6
-
26
-
-
41949141411
-
Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions visualized with ubiquitin-binding protein p62 immunohistochemistry
-
Pikkarainen M, Hartikainen P, Alafuzoff I. Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions visualized with ubiquitin-binding protein p62 immunohistochemistry. J Neuropathol Exp Neurol 2008; 67: 280-98
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, pp. 280-298
-
-
Pikkarainen, M.1
Hartikainen, P.2
Alafuzoff, I.3
-
27
-
-
72649087184
-
Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system
-
Wang X, Fan H, Ying Z, Li B, Wang H, Wang G. Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system. Neurosci Lett 2010; 469: 112-16
-
(2010)
Neurosci Lett
, vol.469
, pp. 112-116
-
-
Wang, X.1
Fan, H.2
Ying, Z.3
Li, B.4
Wang, H.5
Wang, G.6
-
28
-
-
68249126141
-
To aggregate or not to aggregate? A new role for p62
-
Moscat J, Diaz-Meco MT. To aggregate or not to aggregate? A new role for p62. EMBO Rep 2009; 10: 804
-
(2009)
EMBO Rep
, vol.10
, pp. 804
-
-
Moscat, J.1
Diaz-Meco, M.T.2
|