Expression of Toll-like receptors by neonatal leukocytes

Pediatric Allergy and Immunology

Volumn 22, Issue 2, 2011, Pages 221-228

  Dasari, Pallave ^a   Zola, Heddy ^b   Nicholson, Ian C ^b  

^a WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

Author keywords

Leukocytes; Monocytes; Neonates; T lymphocytes; Toll like receptors

Indexed keywords

TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9;

ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMATURITY; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; LEUKOCYTE; MONOCYTE; NEWBORN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOBLAST; T LYMPHOCYTE;

ADULT; AGE FACTORS; CELLS, CULTURED; FLOW CYTOMETRY; HUMANS; INFANT, NEWBORN; LEUKOCYTES; MONOCYTES; TOLL-LIKE RECEPTOR 1; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 8; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS;

EID: 79951795840     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2010.01091.x     Document Type: Article

References (33)

1. Levy O. Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat Rev Immunol 2007: 7: 379-90.
2. Velilla PA, Rugeles MT, Chougnet CA. Defective antigen-presenting cell function in human neonates. Clin Immunol 2006: 121: 251-9.
3. Siegrist CA. The challenges of vaccine responses in early life: selected examples. J Comp Pathol 2007: 137 (Suppl 1): S4-9.
4. The World Health Report 2005. Make every mother and child count. World Health Organisation. Geneva:WHO Press 2005.
5. Janeway CA Jr, Medzhitov R. Innate immune recognition. Annu Rev Immunol 2002: 20: 197-216.
6. Medzhitov R, Janeway CA Jr. Innate immunity: the virtues of a nonclonal system of recognition. Cell 1997: 91: 295-8.
7. Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF. A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci USA 1998: 95: 588-93.
8. Takeuchi O, Kawai T, Sanjo H, et al. TLR6: A novel member of an expanding toll-like receptor family. Gene 1999: 231: 59-65.
9. Du X, Poltorak A, Wei Y, Beutler B. Three novel mammalian toll-like receptors: gene structure, expression, and evolution. Eur Cytokine Netw 2000: 11: 362-71.
10. Chuang T, Ulevitch RJ. Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells. Biochim Biophys Acta 2001: 1518: 157-61.
11. Dasari P, Nicholson IC, Zola H. Toll-like receptors. J Biol Regul Homeost Agents 2008: 22: 17-26.
12. Morgado JM, Pratas R, Laranjeira P, et al. The phenotypical and functional characteristics of cord blood monocytes and CD14(-/low)/CD16(+) dendritic cells can be relevant to the development of cellular immune responses after transplantation. Transpl Immunol 2008: 19: 55-63.
13. Komai-Koma M, Jones L, Ogg GS, Xu D, Liew FY. TLR2 is expressed on activated T cells as a costimulatory receptor. Proc Natl Acad Sci U S A 2004: 101: 3029-34.
14. Cottalorda A, Verschelde C, Marcais A, et al. TLR2 engagement on CD8 T cells lowers the threshold for optimal antigen-induced T cell activation. Eur J Immunol 2006: 36: 1684-93.
15. Mazzoni A, Segal DM. Controlling the Toll road to dendritic cell polarization. J Leukoc Biol 2004: 75: 721-30.
16. Peng G, Guo Z, Kiniwa Y, et al. Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Science 2005: 309: 1380-4.
17. Visintin A, Mazzoni A, Spitzer JH, Wyllie DH, Dower SK, Segal DM. Regulation of Toll-like receptors in human monocytes and dendritic cells. J Immunol 2001: 166: 249-55.
18. Hornung V, Rothenfusser S, Britsch S, et al. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 2002: 168: 4531-7.
19. Nakao Y, Funami K, Kikkawa S, et al. Surface-expressed TLR6 participates in the recognition of diacylated lipopeptide and peptidoglycan in human cells. J Immunol 2005: 174: 1566-73.
20. Lun SW, Wong CK, Ko FW, Hui DS, Lam CW. Expression and functional analysis of Toll-like receptors of peripheral Blood cells in asthmatic patients: implication for immunopathological mechanism in asthma. J Clin Immunol 2008: 29: 330-42.
21. Saikh KU, Kissner TL, Sultana A, Ruthel G, Ulrich RG. Human monocytes infected with Yersinia pestis express cell surface TLR9 and differentiate into dendritic cells. J Immunol 2004: 173: 7426-34.
22. Sadeghi K, Berger A, Langgartner M, et al. Immaturity of infection control in preterm and term newborns is associated with impaired toll-like receptor signaling. J Infect Dis 2007: 195: 296-302.
23. Viemann D, Dubbel G, Schleifenbaum S, Harms E, Sorg C, Roth J. Expression of toll-like receptors in neonatal sepsis. Pediatr Res 2005: 58: 654-9.
24. Levy O, Suter EE, Miller RL, Wessels MR. Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells. Blood 2006: 108: 1284-90.
25. Saikh KU, Lee JS, Kissner TL, Dyas B, Ulrich RG. Toll-like receptor and cytokine expression patterns of CD56+ T cells are similar to natural killer cells in response to infection with Venezuelan equine encephalitis virus replicons. J Infect Dis 2003: 188: 1562-70.
26. Wesch D, Beetz S, Oberg HH, Marget M, Krengel K, Kabelitz D. Direct costimulatory effect of TLR3 ligand poly(I:C) on human gamma delta T lymphocytes. J Immunol 2006: 176: 1348-54.
27. Bell MP, Svingen PA, Rahman MK, Xiong Y, Faubion WA Jr. FOXP3 regulates TLR10 expression in human T regulatory cells. J Immunol 2007: 179: 1893-900.
28. Babu S, Blauvelt CP, Kumaraswami V, Nutman TB. Cutting edge: diminished T cell TLR expression and function modulates the immune response in human filarial infection. J Immunol 2006: 176: 3885-9.
29. Crellin NK, Garcia RV, Hadisfar O, Allan SE, Steiner TS, Levings MK. Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells. J Immunol 2005: 175: 8051-9.
30. Elliott SR, Macardle PJ, Zola H. Removal of erythroid cells from umbilical cord blood mononuclear cell preparations using magnetic beads and a monoclonal antibody against glycophorin A. J Immunol Methods 1998: 217: 121-30.
31. Fuss IJ, Kanof ME, Smith PD, Zola H. Isolation of whole mononuclear cells from peripheral blood and cord blood. Curr Protoc Immunol 2009: 1-7. Chapter 7: Unit7 1.
32. Eaton-Bassiri A, Dillon SB, Cunningham M, et al. Toll-like receptor 9 can be expressed at the cell surface of distinct populations of tonsils and human peripheral blood mononuclear cells. Infect Immun 2004: 72: 7202-11.
33. Dasari P, Nicholson IC, Hodge G, Dandie GW, Zola H. Expression of toll-like receptors on B lymphocytes. Cell Immunol 2005: 236: 140-5.