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Volumn 7, Issue 1, 2011, Pages 89-96

Optimal glycemic control in the elderly: Where is the evidence and who should be targeted?

Author keywords

cognitive impairment; dementia; diabetes mellitus; elderly; hypoglycemia; pharmacology

Indexed keywords

APOLIPOPROTEIN E; DIPEPTIDYL PEPTIDASE IV INHIBITOR; EXENDIN 4; GLICLAZIDE; GLIPIZIDE; GLITAZONE DERIVATIVE; HEMOGLOBIN A1C; INSULIN; LIRAGLUTIDE; METFORMIN; PIOGLITAZONE; ROSIGLITAZONE; SULFONYLUREA DERIVATIVE;

EID: 79951750306     PISSN: 1745509X     EISSN: 17455103     Source Type: Journal    
DOI: 10.2217/ahe.10.86     Document Type: Review
Times cited : (5)

References (53)
  • 1
    • 0031897103 scopus 로고    scopus 로고
    • Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults: The Third National Health and Nutrition Examination Survey, 1988-1994
    • DOI 10.2337/diacare.21.4.518
    • Harris MI, Flegal KM, Cowie CC et al.: Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults: The Third National Health and Nutrition Examination Survey, 1988-1994. Diabetes Care 21, 518-524 (1998). (Pubitemid 28172927)
    • (1998) Diabetes Care , vol.21 , Issue.4 , pp. 518-524
    • Harris, M.I.1    Flegal, K.M.2    Cowie, C.C.3    Eberhardt, M.S.4    Goldstein, D.E.5    Little, R.R.6    Wiedmeyer, H.-M.7    Byrd-Holt, D.D.8
  • 2
    • 0035847591 scopus 로고    scopus 로고
    • DECODE study group, on behalf of the European Epidemiology Group: Glucose tolerances and cardiovascular mortality: Comparison of fasting and 2-hour diagnostic criteria
    • DECODE study group, on behalf of the European Epidemiology Group: Glucose tolerances and cardiovascular mortality: comparison of fasting and 2-hour diagnostic criteria. Arch. Intern. Med. 162, 397-405 (2001).
    • (2001) Arch. Intern. Med. , vol.162 , pp. 397-405
  • 3
    • 0028069788 scopus 로고
    • NIDDM and its metabolic control predict coronary heart disease in elderly subjects
    • Kuusisto J, Mykkänen L, Pyörälä K, Laakso M: NIDDM and its metabolic control predict coronary heart disease in elderly subjects. Diabetes 43, 960-967 (1994). (Pubitemid 24230698)
    • (1994) Diabetes , vol.43 , Issue.8 , pp. 960-967
    • Kuusisto, J.1    Mykkanen, L.2    Pyorala, K.3    Laakso, M.4
  • 5
    • 0036517377 scopus 로고    scopus 로고
    • Diabetes-related morbidity and mortality in a national sample of U.S. elders
    • DOI 10.2337/diacare.25.3.471
    • Bertoni AG, Krop JS, Anderson GF, Brancati FL: Diabetes-related morbidity and mortality in a national sample of U.S. elders. Diabetes Care 25, 471-475 (2002). (Pubitemid 41103338)
    • (2002) Diabetes Care , vol.25 , Issue.3 , pp. 471-475
    • Bertoni, A.G.1    Krop, J.S.2    Anderson, G.F.3    Brancati, F.L.4
  • 6
    • 65749098338 scopus 로고    scopus 로고
    • Canadian Diabetes Association 2008 clinical practice guidelines for the prevention and management of diabetes in Canada
    • Meneilly GS, Tessier D: Canadian Diabetes Association 2008 clinical practice guidelines for the prevention and management of diabetes in Canada. Can. J. Diabetes 32, S181-S186 (2008).
    • (2008) Can. J. Diabetes , vol.32
    • Meneilly, G.S.1    Tessier, D.2
  • 7
    • 0037968349 scopus 로고    scopus 로고
    • California Healthcare Foundation/American Geriatrics Society on Improving Care for Elders with Diabetes: Guidelines for improving the care of the older person with diabetes mellitus
    • California Healthcare Foundation/American Geriatrics Society on Improving Care for Elders with Diabetes: guidelines for improving the care of the older person with diabetes mellitus. J. Am. Geriatr. Soc. 51, S265-S280 (2003).
    • (2003) J. Am. Geriatr. Soc. , vol.51
  • 8
    • 0032511583 scopus 로고    scopus 로고
    • UK Prospective Diabetes Study (UKPDS) Group: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with Type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with Type 2 diabetes (UKPDS 33). Lancet 352, 837-853 (1998).
    • (1998) Lancet , vol.352 , pp. 837-853
  • 10
    • 45149131667 scopus 로고    scopus 로고
    • The Action of Control Cardiovascular Risk in Diabetes Study Group: Effects of intensive glucose lowering in Type 2 diabetes
    • The Action of Control Cardiovascular Risk in Diabetes Study Group: Effects of intensive glucose lowering in Type 2 diabetes. N. Engl. J. Med. 358, 2545-2559 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2545-2559
  • 11
    • 45149133036 scopus 로고    scopus 로고
    • The ADVANCE Collaborative Group: Intensive blood glucose control and vascular outcomes in patients with Type 2 diabetes
    • The ADVANCE Collaborative Group: Intensive blood glucose control and vascular outcomes in patients with Type 2 diabetes. N. Engl. J. Med. 358, 2560-2572 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2560-2572
  • 12
    • 58149389215 scopus 로고    scopus 로고
    • Glucose control and vascular complications in veterans with Type 2 diabetes
    • Duckworth W, Abraira C, Moritz T et al.: Glucose control and vascular complications in veterans with Type 2 diabetes. N. Engl. J. Med. 360, 129-139 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 129-139
    • Duckworth, W.1    Abraira, C.2    Moritz, T.3
  • 13
    • 84863173671 scopus 로고    scopus 로고
    • The association between symptomatic, severe hypoglycaemia and mortality in Type 2 diabetes: Retrospective epidemiological analysis of the ACCORD study
    • Bonds DE, Miller ME, Bergenstal RM et al.: The association between symptomatic, severe hypoglycaemia and mortality in Type 2 diabetes: retrospective epidemiological analysis of the ACCORD study. BMJ 339, 4909-4918 (2009).
    • (2009) BMJ , vol.339 , pp. 4909-4918
    • Bonds, D.E.1    Miller, M.E.2    Bergenstal, R.M.3
  • 14
    • 70349881450 scopus 로고    scopus 로고
    • Intensive glucose control and macrovascular outcomes in Type 2 diabetes
    • Turnbull FM, Abraira C, Anderson RJ et al.: Intensive glucose control and macrovascular outcomes in Type 2 diabetes. Diabetologia 52, 2288-2298 (2009).
    • (2009) Diabetologia , vol.52 , pp. 2288-2298
    • Turnbull, F.M.1    Abraira, C.2    Anderson, R.J.3
  • 15
    • 70349237376 scopus 로고    scopus 로고
    • Intensive glucose therapy and clinical implications of recent data: A consensus statement from the Global Task Force on Glycaemic Control
    • Akalin S, Berntorp K, Ceriello A et al.: Intensive glucose therapy and clinical implications of recent data: a consensus statement from the Global Task Force on Glycaemic Control. Int. J. Clin. Pract. 63, 1421-1425 (2009).
    • (2009) Int. J. Clin. Pract. , vol.63 , pp. 1421-1425
    • Akalin, S.1    Berntorp, K.2    Ceriello, A.3
  • 16
    • 77954340252 scopus 로고    scopus 로고
    • Strict glycaemic control in diabetic patients with CKD or ESRD: Beneficial or deadly?
    • Schernthaner G, Ritz E, Schernthaner G-H: Strict glycaemic control in diabetic patients with CKD or ESRD: beneficial or deadly? Nephrol. Dial. Transplant. 25, 2044-2046 (2010).
    • (2010) Nephrol. Dial. Transplant. , vol.25 , pp. 2044-2046
    • Schernthaner, G.1    Ritz, E.2    Schernthaner, G.-H.3
  • 18
    • 77951039382 scopus 로고    scopus 로고
    • Severe hypoglycaemia leading to hospital admission in Type 2 diabetic patients aged 80 years or older
    • Greco D, Pisciotta M, Gambina F, Maggio F: Severe hypoglycaemia leading to hospital admission in Type 2 diabetic patients aged 80 years or older. Exp. Clin. Endocrinol. Diabetes 118, 215-219 (2010).
    • (2010) Exp. Clin. Endocrinol. Diabetes , vol.118 , pp. 215-219
    • Greco, D.1    Pisciotta, M.2    Gambina, F.3    Maggio, F.4
  • 19
    • 0030852089 scopus 로고    scopus 로고
    • Incidence and risk factors for serious hypoglycemia in older persons using insulin or sulfonylureas
    • Shorr RI, Ray WA, Daugherty JR, Griffin MR.: Incidence and risk factors for serious hypoglycaemia in older persons using insulin or sulfonylureas. Arch. Int. Med. 157, 1681-1686 (1997). (Pubitemid 27327403)
    • (1997) Archives of Internal Medicine , vol.157 , Issue.15 , pp. 1681-1686
    • Shorr, R.I.1    Ray, W.A.2    Daugherty, J.R.3    Griffin, M.R.4
  • 22
    • 0028292096 scopus 로고
    • Frequency of severe hypoglycaemia in patients with Type 1 diabetes with impaired awareness of hypoglycaemia
    • Gold AE, MacLeod KM, Frier BM: Frequency of severe hypoglycaemia in patients with Type 1 diabetes with impaired awareness of hypoglycaemia. Diabetes Care 17, 697-702 (1994).
    • (1994) Diabetes Care , vol.17 , pp. 697-702
    • Gold, A.E.1    MacLeod, K.M.2    Frier, B.M.3
  • 24
    • 0031969717 scopus 로고    scopus 로고
    • Perceived symptoms of hypoglycaemia in elderly Type 2 diabetic patients treated with insulin
    • DOI 10.1002/(SICI)1096-9136(199805)15:5<398::AID-DIA595>3.0.CO;2-B
    • Jaap AJ, Jones GC, McCrimmon RJ, Deary IJ, Frier BM: Perceived symptoms of hypoglycaemia in elderly Type 2 diabetic patients treated with insulin. Diabet. Med. 15, 398-401 (1998). (Pubitemid 28197108)
    • (1998) Diabetic Medicine , vol.15 , Issue.5 , pp. 398-401
    • Jaap, A.J.1    Jones, G.C.2    McCrimmon, R.J.3    Deary, I.J.4    Frier, B.M.5
  • 25
    • 0034797567 scopus 로고    scopus 로고
    • Symptoms of hypoglycaemia in people with diabetes
    • DOI 10.1046/j.1464-5491.2001.00620.x
    • McAulay V, Deary IJ, Frier BM: Symptoms of hypoglycaemia in people with diabetes. Diabet. Med. 18, 690-705 (2001). (Pubitemid 32955520)
    • (2001) Diabetic Medicine , vol.18 , Issue.9 , pp. 690-705
    • McAulay, V.1    Deary, I.J.2    Frier, B.M.3
  • 26
    • 0028009378 scopus 로고
    • Counterregulatory hormone responses to hypoglycemia in the elderly patient with diabetes
    • Meneilly GS, Cheung E, Tuokko H: Counterregulatory hormone responses to hypoglycemia in the elderly patient with diabetes. Diabetes 43, 403-410 (1994). (Pubitemid 24064247)
    • (1994) Diabetes , vol.43 , Issue.3 , pp. 403-410
    • Meneilly, G.S.1    Cheung, E.2    Tuokko, H.3
  • 27
    • 0036314189 scopus 로고    scopus 로고
    • Hypoglycemia-associated autonomic failure in advanced type 2 diabetes
    • Segel SA, Paramore DS, Cryer PE: Hypoglycemia-associated autonomic failure in advanced Type 2 diabetes. Diabetes 51, 724-733 (2002). (Pubitemid 34760182)
    • (2002) Diabetes , vol.51 , Issue.3 , pp. 724-733
    • Segel, S.A.1    Paramore, D.S.2    Cryer, P.E.3
  • 28
    • 84863173671 scopus 로고    scopus 로고
    • The effects of baseline characteristics, glycaemia treatment approach, and glycated haemoglobin concentration on the risk of severe hypoglycaemia: Post hoc epidemiological analysis of the ACCORD study
    • Miller ME, Bonds DE, Gerstein HC et al.: The effects of baseline characteristics, glycaemia treatment approach, and glycated haemoglobin concentration on the risk of severe hypoglycaemia: post hoc epidemiological analysis of the ACCORD study. BMJ 304, 5444-5456 (2010).
    • (2010) BMJ , vol.304 , pp. 5444-5456
    • Miller, M.E.1    Bonds, D.E.2    Gerstein, H.C.3
  • 29
    • 77954159481 scopus 로고    scopus 로고
    • Epidemiological relationships between A1c and all-cause mortality during a median 3.4 year follow-up of glycemic treatment in the ACCORD trial
    • Riddle MC, Ambrosius WT, Brillon DJ et al.: Epidemiological relationships between A1c and all-cause mortality during a median 3.4 year follow-up of glycemic treatment in the ACCORD trial. Diabetes Care 33, 983-990 (2010).
    • (2010) Diabetes Care , vol.33 , pp. 983-990
    • Riddle, M.C.1    Ambrosius, W.T.2    Brillon, D.J.3
  • 30
    • 77957742069 scopus 로고    scopus 로고
    • Severe hypoglycaemia and risks of vascular events and death
    • Zoungas S, Patel A, Chalmers J et al.: Severe hypoglycaemia and risks of vascular events and death. N. Engl. J. Med. 262, 1410-1418 (2010).
    • (2010) N. Engl. J. Med. , vol.262 , pp. 1410-1418
    • Zoungas, S.1    Patel, A.2    Chalmers, J.3
  • 31
    • 0032707190 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus, cognitive impairment and dementia
    • Stewart R, Liolitsa D: Type 2 diabetes mellitus, cognitive impairment and dementia. Diabet. Med. 16, 93-112 (1999).
    • (1999) Diabet. Med. , vol.16 , pp. 93-112
    • Stewart, R.1    Liolitsa, D.2
  • 32
    • 29044449855 scopus 로고    scopus 로고
    • Risk of dementia in diabetes mellitus: A systematic review
    • DOI 10.1016/S1474-4422(05)70284-2, PII S1474442205702842
    • Biessels GJ, Stackenborg S, Brunner E, Brayne C, Scheltens P: Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol. 5, 64-74 (2006). (Pubitemid 41790697)
    • (2006) Lancet Neurology , vol.5 , Issue.1 , pp. 64-74
    • Biessels, G.J.1    Staekenborg, S.2    Brunner, E.3    Brayne, C.4    Scheltens, P.5
  • 33
    • 64249141005 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus, hypertension, dyslipidemia and obesity: A systematic comparison of their impact on cognition
    • Van den Berg E, Kloppenborg RP, Kessels RP, Kappelle LJ, Biessels GJ: Type 2 diabetes mellitus, hypertension, dyslipidemia and obesity: a systematic comparison of their impact on cognition. Biochim. Biophys. Acta 1792, 470-481 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1792 , pp. 470-481
    • Van Den Berg, E.1    Kloppenborg, R.P.2    Kessels, R.P.3    Kappelle, L.J.4    Biessels, G.J.5
  • 34
    • 67650138159 scopus 로고    scopus 로고
    • Cognitive dysfunction and its clinical and radiological determinants in patients with symptomatic arterial disease and diabetes
    • Tiehuis AM, Mali WP, van Raamt AF et al.: Cognitive dysfunction and its clinical and radiological determinants in patients with symptomatic arterial disease and diabetes. J. Neurol. Sci. 283, 170-174 (2009).
    • (2009) J. Neurol. Sci. , vol.283 , pp. 170-174
    • Tiehuis, A.M.1    Mali, W.P.2    Van Raamt, A.F.3
  • 36
    • 33646383887 scopus 로고    scopus 로고
    • Improving metabolic control leads to better working memory in adults with type 2 diabetes
    • Ryan CM, Freed MI, Rood JA, Cobitz AR, Waterhouse BR, Strachan MW: Improving metabolic control leads to better working memory in adults with Type 2 diabetes. Diabetes Care 29, 345-351 (2006). (Pubitemid 44106516)
    • (2006) Diabetes Care , vol.29 , Issue.2 , pp. 345-351
    • Ryan, C.M.1    Freed, M.I.2    Rood, J.A.3    Cobitz, A.R.4    Waterhouse, B.R.5    Strachan, M.W.J.6
  • 37
    • 65549155203 scopus 로고    scopus 로고
    • Living beyond our physiological means: Small vessel disease of the brain is an expression of systemic failure in arteriolar function: A unifying hypothesis
    • Thompson CS, Hakim AM: Living beyond our physiological means: small vessel disease of the brain is an expression of systemic failure in arteriolar function: a unifying hypothesis. Stroke 40, e322-e330 (2009).
    • (2009) Stroke , vol.40
    • Thompson, C.S.1    Hakim, A.M.2
  • 38
    • 70349850941 scopus 로고    scopus 로고
    • Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with Type 2 diabetes: The Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial
    • De Galan BE, Zoungas S, Chalmers J et al.: Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with Type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial. Diabetologia 52, 2328-2336 (2009).
    • (2009) Diabetologia , vol.52 , pp. 2328-2336
    • De Galan, B.E.1    Zoungas, S.2    Chalmers, J.3
  • 39
    • 68249134074 scopus 로고    scopus 로고
    • The role of apolipoprotein e in Alzheimers disease
    • Kim J, Basak JM, Holtzman DM: The role of apolipoprotein E in Alzheimers disease. Neuron 63, 287-303 (2009).
    • (2009) Neuron , vol.63 , pp. 287-303
    • Kim, J.1    Basak, J.M.2    Holtzman, D.M.3
  • 40
    • 70949097121 scopus 로고    scopus 로고
    • Presence of the APOE E4 allele modifies the relationship between Type 2 diabetes and cognitive performance: The Maine-Syracuse study
    • Dore GA, Elias MF, Robbins MA, Elias PK, Nagy Z: Presence of the APOE E4 allele modifies the relationship between Type 2 diabetes and cognitive performance: the Maine-Syracuse study. Diabetologia 52, 2551-2560 (2009).
    • (2009) Diabetologia , vol.52 , pp. 2551-2560
    • Dore, G.A.1    Elias, M.F.2    Robbins, M.A.3    Elias, P.K.4    Nagy, Z.5
  • 41
    • 0033672908 scopus 로고    scopus 로고
    • Cognitive dysfunction in older subjects with diabetes mellitus: Impact on diabetes self-management and use of care services. All Wales Research into Elderly (AWARE) study
    • Sinclair AJ, Girling AJ, Bayer AL: Cognitive dysfunction in older subjects with diabetes mellitus: impact on diabetes self-management and use of care services. All Wales Research into Elderly (AWARE) study. Diabetes Res. Clin. Pract. 50, 203-212 (2000).
    • (2000) Diabetes Res. Clin. Pract. , vol.50 , pp. 203-212
    • Sinclair, A.J.1    Girling, A.J.2    Bayer, A.L.3
  • 42
    • 31544482787 scopus 로고    scopus 로고
    • Dose-response relation between sulfonylurea drugs and mortality in type 2 diabetes mellitus: A population-based cohort study
    • DOI 10.1503/cmaj.050748
    • Simpson SH, Majumdar SR, Tsuyuki RT, Eurich DT, Johnson JA: Dose-response relation between sulfonylurea drugs and mortality in Type 2 diabetes mellitus: a population-based cohort study. CMAJ 174, 169-174 (2006). (Pubitemid 43166269)
    • (2006) Canadian Medical Association Journal , vol.174 , Issue.2 , pp. 169-174
    • Simpson, S.H.1    Majumdar, S.R.2    Tsuyuki, R.T.3    Eurich, D.T.4    Johnson, J.A.5
  • 43
    • 0032511566 scopus 로고    scopus 로고
    • Group effects of intensive blood-glucose control with metformin on complications in overweight patients with Type 2 diabetes (UKPDS 34)
    • UK Prospective Diabetes Study (UKPDS)
    • UK Prospective Diabetes Study (UKPDS): Group effects of intensive blood-glucose control with metformin on complications in overweight patients with Type 2 diabetes (UKPDS 34). Lancet 352, 854-865 (1998).
    • (1998) Lancet , vol.352 , pp. 854-865
  • 44
    • 33646422782 scopus 로고    scopus 로고
    • Risk of mortality and adverse cardiovascular outcomes in Type 2 diabetes: A comparison of patients treated with sulfonylureas and metformin
    • Evans JM, Ogston SA, Emslie-Smith A, Morris AD: Risk of mortality and adverse cardiovascular outcomes in Type 2 diabetes: a comparison of patients treated with sulfonylureas and metformin. Diabetologia 49, 930-936 (2006).
    • (2006) Diabetologia , vol.49 , pp. 930-936
    • Evans, J.M.1    Ogston, S.A.2    Emslie-Smith, A.3    Morris, A.D.4
  • 45
    • 77952911680 scopus 로고    scopus 로고
    • Review: Metformin: Potential benefits and use in chronic kidney diseas
    • Pilmore HL: Review: metformin: potential benefits and use in chronic kidney diseas. Nephrology 15, 412-418 (2010).
    • (2010) Nephrology , vol.15 , pp. 412-418
    • Pilmore, H.L.1
  • 46
    • 75149171976 scopus 로고    scopus 로고
    • Meformin: Safety in cardiac patients
    • Khurana R, Malik IS: Meformin: safety in cardiac patients. Heart 96, 99-102 (2010).
    • (2010) Heart , vol.96 , pp. 99-102
    • Khurana, R.1    Malik, I.S.2
  • 47
    • 0037031267 scopus 로고    scopus 로고
    • Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus
    • DOI 10.1161/01.CIR.0000025403.20953.23
    • Haffner SM, Greenberg AS, Weston WM, Chen H, Williams K, Freed MI: Effects of rosiglitazone treatment on non-traditional markers of cardiovascular disease in patients with Type 2 diabetes mellitus. Circulation 106, 679-684 (2002). (Pubitemid 34851926)
    • (2002) Circulation , vol.106 , Issue.6 , pp. 679-684
    • Haffner, S.M.1    Greenberg, A.S.2    Weston, W.M.3    Chen, H.4    Williams, K.5    Freed, M.I.6
  • 49
    • 10744221639 scopus 로고    scopus 로고
    • Thiazolidinedione use, fluid retention, and congestive heart failure
    • Nesto RW, Bell D, Bonow RO et al.: Thiazolidinedione use, fluid retention, and congestive heart failure. Diabetes Care 27, 256-263 (2004).
    • (2004) Diabetes Care , vol.27 , pp. 256-263
    • Nesto, R.W.1    Bell, D.2    Bonow, R.O.3
  • 50
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen SE, Wolski K: Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N. Engl. J. Med. 356, 2457-2471 (2007). (Pubitemid 46919772)
    • (2007) New England Journal of Medicine , vol.356 , Issue.24 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 51
    • 77954988618 scopus 로고    scopus 로고
    • Risk of acute myocardial infarction, stroke, heart failure, and death in elderly Medicare patients treated with rosiglitazone or pioglitazone
    • Graham DJ, Ouellet-Hellstrom R, MaCurdy TE et al.: Risk of acute myocardial infarction, stroke, heart failure, and death in elderly Medicare patients treated with rosiglitazone or pioglitazone. JAMA 304, 411-418 (2010).
    • (2010) JAMA , vol.304 , pp. 411-418
    • Graham, D.J.1    Ouellet-Hellstrom, R.2    MacUrdy, T.E.3


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