Severe hypoglycaemia leading to hospital admission in type 2 diabetic patients aged 80 years or older

Experimental and Clinical Endocrinology and Diabetes

Volumn 118, Issue 4, 2010, Pages 215-219

  Greco, D ^a   Pisciotta, M ^a   Gambina, F ^a   Maggio, F ^a  

^a Division of Diabetology S Biagio Hospital Marsala (TP)   (Italy)

Author keywords

Dementia; Elderly; Long acting sulphonylurea; Risk factors; Severe hypoglycaemia; Type 2 diabetes

Indexed keywords

ACARBOSE; GLIBENCLAMIDE; GLICLAZIDE; GLIMEPIRIDE; GLIQUIDONE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; METFORMIN; REPAGLINIDE;

AGED; ARTICLE; COGNITIVE DEFECT; COMORBIDITY; DIABETIC PATIENT; DISEASE SEVERITY; GLUCOSE BLOOD LEVEL; HOSPITAL ADMISSION; HUMAN; HYPOGLYCEMIA; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RISK FACTOR;

AGED, 80 AND OVER; BLOOD GLUCOSE SELF-MONITORING; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSE; GLYBURIDE; HOSPITALIZATION; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; INCIDENCE; MALE; PATIENT ADMISSION; RISK FACTORS;

EID: 77951039382     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0029-1241823     Document Type: Article

References (31)

1. Allicar M, Megas F, Houzard S, etal. Frequency and costs of hospital stays for hypoglycemia in France in 1995. Presse Med 2000 29 837-853
2. Amiel SA, Dixon T, Mann R, etal. Hypoglycaemia in type 2 diabetes. Diabet Med 2008 25 245-254
3. Asplund K, Wiholm BE, Lithner F. Glibenclamide-associated hypoglycaemia: a report on 57 cases. Diabetologia 1983 24 412-417
4. Baxter MA. The role of new basal insulin analogues in the initiation and optimisation of insulin therapy in type 2 diabetes. Acta Diabetol 2008 45 253-268
5. Ben-Ami H, Nagachandran P, Mendelson A, etal. Drug-induced hypoglycemic coma in 102 diabetic patients. Arch Intern Med 1999 159 281-284
6. Biessels GJ, Staekenborg S, Brunner E, etal. Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol 2006 5 64-74
7. Chau D, Edelman SV. Clinical management of diabetes in the elderly. Clinical Diabetes 2001 19 172-175
8. Chelliah A, Burge MR. Hypoglycaemia in elderly patients with diabetes mellitus. Drugs Aging 2004 21 511-530
9. Cockroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976 16 31-41
10. Culy CR, Jarvis B. Repaglinide: a review of its therapeutic use in type 2 diabetes mellitus. Drugs 2001 61 1625-1660
11. Gangji AS, Goldsmith CH, Cukierman T, etal. A systematic review and meta-analysis of hypoglycemia and cardiovascular events. Diabetes Care 2007 30 389-394
12. Greco D, Angileri G. Drug-induced severe hypoglycemia in type 2 diabetic patients aged 80 years or older. Diab Nutr Metab 2004 17 23-26
13. Holstein A, Plaschke A, Eick-Hartwig E. Lower incidence of severe hypoglycaemia in patients with type 2 diabetes treated with glimepiride versus glibenclamide. Diabetes Metab Res Rev 2001 17 467-473
14. Holstein A, Plaschke A, Egberts EH. Incidence and costs of severe hypoglycaemia. Diabetes Care 2002 25 2109-2110
15. Holstein A, Plaschke A, Egberts EH. Clinical characterisation of severe hypoglycaemia: a prospective population-based study. Exp Clin Endocrinol Diabetes 2003 111 364-369
16. Holstein A, Egberts EH. Risk of hypoglycaemia with oral antidiabetic agents in patients with type 2 diabetes. Exp Clin Endocrinol Diabetes 2003 111 405-414
17. Jaap AJ, Jones GC, McCrimman RJ, etal. Perceived symptoms of hypoglycaemia in type 2 diabetic patients treated with insulin. Diabet Med 1988 15 398-401
18. Lardinois CK. Type 2 diabetes: glycemic targets and oral therapies for older patients. Geriatrics 1998 53 22-28
19. McAulay V, Frier BM. Insulin analogues and other development in insulin therapy for diabetes. Expert Opin Pharmaco-Ther 2003 4 1141-1156
20. Mutch WJ, Dingwall-Fordyce I. Is it a hypo? Knowledge of the symptoms of hypoglycaemia in elderly diabetic patients. Diabet Med 1985 2 54-56
21. Nattras M, Lauritzen T. Review of prandial glucose regulation with repaglinide: a solution to the problem of hypoglycaemia in the treatment of type 2 diabetes? Int J Obesity 2000 24 (Suppl. 3) S21-S31
22. Pegg A, Fitzgerald D, Wise D, etal. A community-based study of diabetes-related skills and knowledge in elderly people with insulin-requiring diabetes. Diabet Med 1991 8 778-781
23. Rosenstock J. Management of type 2 diabetes mellitus in the elderly. Special considerations. Drugs Aging 2001 18 31-40
24. Seltzer HS. Drug-induced hypoglycemia: a review of 1418 cases. Endocrinol Metab Clin North Am 1999 18 163-183
25. Shorr RI, Ray WA, Daugherty JR, etal. Individual sulfonylureas and serious hypoglycemia in older people. J Am Geriatr Soc 1996 44 871-872
26. Shorr RI, Ray WA, Daugherty JR, etal. Incidence and risk factors for serious hypoglycemia in older persons using insulin or sulfonylureas. Arch Intern Med 1997 157 1681-1686
27. Stahl M, Berger W. Higher incidence of severe hypoglycaemia leading to hospital admission in type 2 diabetic patients treated with long-acting versus short-acting sulphonylureas. Diabet Med 1999 16 586-590
28. Thomson FJ, Masson EA, Leeming JT, etal. Lack of knowledge of symptoms of hypoglycaemia by elderly diabetic patients. Age Ageing 1991 20 404-406
29. van Staa T, Abenhaim L, Monette J. Rates of hypoglycemia in users of sulfonylureas. J Clin Epidemiol 1997 50 735-741
30. Whitmer RA, Karter AJ, Yaffe K, etal. Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus. JAMA 2009 301 1565-1572
31. Zammitt NN, Frier BM. Hypoglycaemia in type 2 diabetes. Diabetes Care 2005 28 2948-2961