Electrocardiography as an early cardiac screening test in children with mitochondrial disease

Korean Journal of Pediatrics

Volumn 53, Issue 5, 2010, Pages 644-647

  Baik, Ran ^a   Chae, Jung Hyun ^a   Lee, Young Mock ^a   Kang, Hoon Chul ^a   Lee, Joon Soo ^a   Kim, Heung Dong ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Child; Conductivity; Electrocardiography; Heart; Mitochondria; Respiratory chain

Indexed keywords

EID: 79951708878     PISSN: 17381061     EISSN: 20927258     Source Type: Journal    
DOI: 10.3345/kjp.2010.53.5.644     Document Type: Article

References (30)

1. MacFarland R, Taylor RW, Turnbull DM. Mitochondrial diseases-its impact, etiology, and pathology. Curr Top Dev Biol 2007;77:113-55.
2. Finsterer J. Mitochondriopathies. Eur J Neurol 2004;11:163-86.
3. Munnich A, Rötig A, Chretien D, Cormire V, Bourgeron T, Bonnefont JP, et al. Clinical presentation of mitochondrial disorders in childhood. J Inherited Metab Dis 1996;19:521-7.
4. Gillis L, Kaye E. Diagnosis and management of mitochondrial diseases. Pediatr Clin N Am 2002;49:203-19.
5. Haas RH, Parikh S, Falk MJ, Saneto RP, Wolf NI, Darin N, et al. Mitochondrial disease: a practical approach for primary care physicians. Pediatrics 2007;120:1326-33.
6. Bettinelli A, Tosetto C, Colussi G, Tommasini G, Edefonti A, Bianchetti MG. Electrocardiogram with prolonged QT interval in Gitelman disease. Kidney Int 2002;62:580-4.
7. Bondy CA, Ceniceros I, Van PL, Bakalov VK, Rosing DR. Prolonged rate-corrected QT interval and other electrocardiogram abnormalities in girls with Turner syndrome. Pediatrics 2006;118:e1220-5.
8. Baumgartner D, Scholl-Bürgi S, Sass JO, Sperl W, Schweigmann U, Stein JI, et al. Prolonged QTc intervals and decreased left ventricular contractility in patients with propionic acidemia. J Pediatr 2007;150:192-7.
9. Giunti S, Bruno G, Lillaz E, Gruden G, Lolli V, Chaturvedi N, et al. Incidence and risk factors of prolonged QTc interval in type 1 diabetes: the EURODIAB Prospective Complications Study. Diabetes Care 2007;30:2057-63.
10. Soliman OI, van der Beek NA, van Doorn PA, Vletter WB, Nemes A, Van Dalen BM, et al. Cardiac involvement in adults with Pompe disease. J Intern Med 2008;264:333-9.
11. Lev D, Nissenkorn A, Leshinsky-Silver E, Sadeh M, Zeharia A, Garty BZ, et al. Clinical presentations of mitochondrial cardiomyopathies. Pediatr Cardiol 2004;25:443-50.
12. Holmgren D, Wåhlander H, Eriksson BO, Oldfors A, Holme E, Tulinius M. Cardiomyopathy in children with mitochondrial disease; clinical course and cardiological findings. Eur Heart J 2003;24:280-8.
13. Finsterer J, Stöllberger C, Blazek G, Kunafer M, Prager E. Cardiac involvement over 10 years in myotonic and Becker muscular dystrophy and mitochondrial disorder. Int J Cardiol 2007;119:176-84.
14. Finsterer J. Overview on visceral manifestations of mitochondrial disorders. Neth J Med 2006;64:61-71.
15. Rustin P, Chretien D, Bourgeron T, Gérard B, Rötig A, Saudubray JM, et al. Biochemical and molecular investigations in respiratory chain deficiencies. Clin Chim Acta 1994;228:35-51.
16. Desai M, Li L, Desta Z, Malik M, Flockhart D. Variability of heart rate correction methods for the QT interval. Br J Clin Pharmacol 2003;55:511-7.
17. Piccirillo G, Magrì D, Matera S, Magnanti M, Torrini A, Pasquazzi E, et al. QT variability strongly predicts sudden cardiac death in asymptomatic subjects with mild or moderate left ventricular systolic dysfunction: a prospective study. Eur Heart J 2007;28:1344-50.
18. Schouten EG, Dekker JM, Meppelink P, Kok FJ, Vandenbroucke JP, Pool J. QT interval prolongation predicts cardiovascular mortality in an apparently healthy population. Circulation 1991;84:1516-23.
19. van Noord C, Straus SM, Sturkenboom MC, Hofman A, Aarnoudse AJ, Bagnardi V, et al. Psycotropic drugs associated with corrected QT interval prolongation. J Clin Psychopharmacol 2009;29:9-15.
20. Salles GF, Bloch KV, Cardoso CR. Mortality and predictors of mortality in a cohort of Brazilian type 2 diabetic patients. Diabetes Care 2004;27:1299-305.
21. Okin PM, Devereux RB, Lee ET, Galloway JM, Howard BV. Electrocardiographic repolarization complexity and abnormality predict all-cause and cardiovascular mortality in diabetes: the strong heart study. Diabetes 2004;53:434-40.
22. Ishikawa K, Kimura S, Kobayashi A, Sato T, Matsumoto H, Ujiie Y, et al. Increased reactive oxygen species and anti-oxidative response in mitochondrial cardiomyopathy. Circ J 2005;69:617-20.
23. Bonnet D, de Lonlay P, Gautier I, Rustin P, Rötig A, Kachaner J, et al. Efficiency of metabolic screening in childhood cardiomyopathies. Eur Heart J 1998;19:790-3.
24. Skinner JR, Yang T, Purvis D, Chung SK, Roden DM, Rees MI. Coinheritance of long QT syndrome and Kearns-Sayre syndrome. Heart Rhythm 2007;4:1568-72.
25. Barrera-Ramírez CF, Barragán-Campos HM, Ilarraza H, Iturralde P, Avila-Casado MC, Oseguera J. Cardiac involvement in Kearns-Sayre syndrome. Rev Esp Cardiol 2005;58:443-6.
26. Bonnet D, Martin D, De Lonlay P, Villain E, Jouvet P, Rabier D, et al. Arrhythmias and conduction defects as presenting symptoms of fatty acid oxidation disorders in children. Circulation 1999;100:2248-53.
27. Koizumi A, Nozaki J, Ohura T, Kayo T, Wada Y, Nezu J, et al. Genetic epidemiology of the carnitine transporter OCTN2 gene in a Japanese population and phenotypic characterization in Japanese pedigrees with primary systemic carnitine deficiency. Hum Mol Genet 1999;8:2247-54.
28. Kim JT, Lee YJ, Lee YM, Kang HC, Lee JS, Kim HD. Clinical characteristics of patients with non-specific and non-categorized mitochondrial diseases. Acta Paediatr 2009;98:1825-9.
29. Lee SM, Kim JH, Lee YM, Lee JS, Kim HD. Evaluation of renal function in children with mitochondrial respiratory chain complex defect: usefulness of cystatin C. Acta Paediatr 2009;98:1014-8.
30. Lee YM, Kang HC, Lee JS, Kim SH, Kim EY, Lee SK, et al. Mitochondrial respiratory chain defects: underlying etiology in various epileptic conditions. Epilepsia 2008;49:685-90.