-
2
-
-
63349087565
-
Genome-wide association studies in type 2 diabetes
-
McCarthy MI, Zeggini E 2009 Genome-wide association studies in type 2 diabetes. Curr Diab Rep 9:164-171
-
(2009)
Curr Diab Rep
, vol.9
, pp. 164-171
-
-
McCarthy, M.I.1
Zeggini, E.2
-
4
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P, Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, et al. 2010 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 42:105-116
-
(2010)
Nat Genet
, vol.42
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
Saxena, R.4
Soranzo, N.5
Jackson, A.U.6
Wheeler, E.7
Glazer, N.L.8
Bouatia-Naji, N.9
Gloyn, A.L.10
Lindgren, C.M.11
Mägi, R.12
Morris, A.P.13
Randall, J.14
Johnson, T.15
Elliott, P.16
Rybin, D.17
Thorleifsson, G.18
Steinthorsdottir, V.19
Henneman, P.20
Grallert, H.21
Dehghan, A.22
Hottenga, J.J.23
Franklin, C.S.24
Navarro, P.25
more..
-
5
-
-
67349270566
-
Translating TCF7L2: From gene to function
-
Pearson ER 2009 Translating TCF7L2: from gene to function. Diabetologia 52:1227-1230
-
(2009)
Diabetologia
, vol.52
, pp. 1227-1230
-
-
Pearson, E.R.1
-
6
-
-
33750889376
-
Transcription factor TCF7L2 genetic study in the French population: Expression in human β-cells and adipose tissue and strong association with type 2 diabetes
-
DOI 10.2337/db06-0474
-
Cauchi S, Meyre D, Dina C, Choquet H, Samson C, Gallina S, Balkau B, Charpentier G, Pattou F, Stetsyuk V, Scharfmann R, Staels B, Frühbeck G, Froguel P 2006 Transcription factor TCF7L2 genetic study in the French population: expression in human β-cells and adipose tissue and strong association with type 2 diabetes. Diabetes 55:2903-2908 (Pubitemid 44923694)
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2903-2908
-
-
Cauchi, S.1
Meyre, D.2
Dina, C.3
Choquet, H.4
Samson, C.5
Gallina, S.6
Balkau, B.7
Charpentier, G.8
Pattou, F.9
Stetsyuk, V.10
Scharfmann, R.11
Staels, B.12
Fruhbeck, G.13
Froguel, P.14
-
7
-
-
41449109466
-
Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a U.K.-resident South Asian population
-
Rees SD, Bellary S, Britten AC, O'Hare JP, Kumar S, Barnett AH, Kelly MA 2008 Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a U.K.-resident South Asian population. BMC Med Genet 9:8
-
(2008)
BMC Med Genet
, vol.9
, pp. 8
-
-
Rees, S.D.1
Bellary, S.2
Britten, A.C.3
O'Hare, J.P.4
Kumar, S.5
Barnett, A.H.6
Kelly, M.A.7
-
8
-
-
33750892139
-
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals
-
DOI 10.2337/db06-0381
-
Saxena R, Gianniny L, Burtt NP, Lyssenko V, Giuducci C, Sjögren M, Florez JC, Almgren P, Isomaa B, Orho-Melander M, Lindblad U, Daly MJ, Tuomi T, Hirschhorn JN, Ardlie KG, Groop LC, Altshuler D 2006 Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals. Diabetes 55:2890-2895 (Pubitemid 44923692)
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2890-2895
-
-
Saxena, R.1
Gianniny, L.2
Burtt, N.P.3
Lyssenko, V.4
Giuducci, C.5
Sjogren, M.6
Florez, J.C.7
Almgren, P.8
Isomaa, B.9
Orho-Melander, M.10
Lindblad, U.11
Daly, M.J.12
Tuomi, T.13
Hirschhorn, J.N.14
Ardlie, K.G.15
Groop, L.C.16
Altshuler, D.17
-
9
-
-
53549133639
-
β-Cell glucose sensitivity is decreased by 39% in non-diabetic individuals carrying multiple diabetes-risk alleles compared with those with no risk alleles
-
Pascoe L, Frayling TM, Weedon MN, Mari A, Tura A, Ferrannini E, Walker M 2008 β-Cell glucose sensitivity is decreased by 39% in non-diabetic individuals carrying multiple diabetes-risk alleles compared with those with no risk alleles. Diabetologia 51:1989-1992
-
(2008)
Diabetologia
, vol.51
, pp. 1989-1992
-
-
Pascoe, L.1
Frayling, T.M.2
Weedon, M.N.3
Mari, A.4
Tura, A.5
Ferrannini, E.6
Walker, M.7
-
10
-
-
67349102328
-
The T allele of rs7903146 TCF7L2is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
-
Pilgaard K, Jensen CB, Schou JH, Lyssenko V, Wegner L, Brøns C, Vilsboll T, Hansen T, Madsbad S, Holst JJ, Volund A, Poulsen P, Groop L, Pedersen O, Vaag AA 2009 The T allele of rs7903146 TCF7L2is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men. Diabetologia 52:1298-1307
-
(2009)
Diabetologia
, vol.52
, pp. 1298-1307
-
-
Pilgaard, K.1
Jensen, C.B.2
Schou, J.H.3
Lyssenko, V.4
Wegner, L.5
Brøns, C.6
Vilsboll, T.7
Hansen, T.8
Madsbad, S.9
Holst, J.J.10
Volund, A.11
Poulsen, P.12
Groop, L.13
Pedersen, O.14
Vaag, A.A.15
-
11
-
-
78049512890
-
Piragliatin (RO4389620), a novel glucokinase activator, lowers plasma glucose both in the postabsorptive state and after a glucose challenge in patients with type 2 diabetes mellitus: A mechanistic study
-
Bonadonna RC, Heise T, Arbet-Engels C, Kapitza C, Avogaro A, Grimsby J, Zhi J, Grippo JF, Balena R 2010 Piragliatin (RO4389620), a novel glucokinase activator, lowers plasma glucose both in the postabsorptive state and after a glucose challenge in patients with type 2 diabetes mellitus: a mechanistic study. J Clin Endocrinol Metab 95:5028-5036
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 5028-5036
-
-
Bonadonna, R.C.1
Heise, T.2
Arbet-Engels, C.3
Kapitza, C.4
Avogaro, A.5
Grimsby, J.6
Zhi, J.7
Grippo, J.F.8
Balena, R.9
-
12
-
-
0034037064
-
Effects of glucosamine infusion on insulin secretion and insulin action in humans
-
Monauni T, Zenti MG, Cretti A, Daniels MC, Targher G, Caruso B, Caputo M, McClain D, Del Prato S, Giaccari A, Muggeo M, Bonora E, Bonadonna RC 2000 Effects of glucosamine infusion on insulin secretion and insulin action in humans. Diabetes 49:926-935 (Pubitemid 30349414)
-
(2000)
Diabetes
, vol.49
, Issue.6
, pp. 926-935
-
-
Monauni, T.1
Zenti, M.G.2
Cretti, A.3
Daniels, M.C.4
Targher, G.5
Caruso, B.6
Caputo, M.7
McClain, D.8
Del, P.S.9
Giaccari, A.10
Muggeo, M.11
Bonora, E.12
Bonadonna, R.C.13
-
13
-
-
43249108322
-
Metabolic abnormalities underlying the different prediabetic phenotypes in obese adolescents
-
DOI 10.1210/jc.2007-1722
-
Calí AM, Bonadonna RC, Trombetta M, Weiss R, Caprio S 2008 Metabolic abnormalities underlying the different prediabetic phenotypes in obese adolescents. J Clin Endocrinol Metab 93:1767-1773 (Pubitemid 351656516)
-
(2008)
Journal of Clinical Endocrinology and Metabolism
, vol.93
, Issue.5
, pp. 1767-1773
-
-
Cali, A.M.G.1
Bonadonna, R.C.2
Trombetta, M.3
Weiss, R.4
Caprio, S.5
-
14
-
-
20144378994
-
β-cell function across the spectrum of glucose tolerance in obese youth
-
DOI 10.2337/diabetes.54.6.1735
-
Weiss R, Caprio S, Trombetta M, Taksali SE, Tamborlane WV, Bonadonna R 2005 β-Cell function across the spectrum of glucose tolerance in obese youth. Diabetes 54:1735-1743 (Pubitemid 40774888)
-
(2005)
Diabetes
, vol.54
, Issue.6
, pp. 1735-1743
-
-
Weiss, R.1
Caprio, S.2
Trombetta, M.3
Taksali, S.E.4
Tamborlane, W.V.5
Bonadonna, R.6
-
15
-
-
34547109615
-
Assessment of β-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests
-
DOI 10.1152/ajpendo.00421.2006
-
Cobelli C, Toffolo GM, DallaMan C, Campioni M, Denti P, Caumo A, Butler P, Rizza R 2007 Assessment of β-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests. Am J Physiol Endocrinol Metab 293:E1-E15 (Pubitemid 47105910)
-
(2007)
American Journal of Physiology - Endocrinology and Metabolism
, vol.293
, Issue.1
-
-
Cobelli, C.1
Toffolo, G.M.2
Man, C.D.3
Campioni, M.4
Denti, P.5
Caumo, A.6
Butler, P.7
Rizza, R.8
-
16
-
-
0035129336
-
A model for glucose control of insulin secretion during 24 h of free living
-
Mari A, Camastra S, Toschi E, Giancaterini A, Gastaldelli A, Mingrone G, Ferrannini E 2001 A model for glucose control of insulin secretion during 24 h of free living. Diabetes 50(Suppl 1):S164-S168 (Pubitemid 32148245)
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL. 1
-
-
Mari, A.1
Camastra, S.2
Toschi, E.3
Giancaterini, A.4
Gastaldelli, A.5
Mingrone, G.6
Ferrannini, E.7
-
17
-
-
77956072830
-
Transcription factor 7-like 2 (TCF7L2) polymorphism and hyperglycemia in an adult Italian population-based cohort
-
Gambino R, Bo S, Gentile L, Musso G, Pagano G, Cavallo-Perin P, Cassader M 2010 Transcription factor 7-like 2 (TCF7L2) polymorphism and hyperglycemia in an adult Italian population-based cohort. Diabetes Care 33:1233-1235
-
(2010)
Diabetes Care
, vol.33
, pp. 1233-1235
-
-
Gambino, R.1
Bo, S.2
Gentile, L.3
Musso, G.4
Pagano, G.5
Cavallo-Perin, P.6
Cassader, M.7
-
18
-
-
33846596193
-
Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
-
Helgason A, Pálsson S, Thorleifsson G, Grant SF, Emilsson V, Gunnarsdottir S, Adeyemo A, Chen Y, Chen G, Reynisdottir I, Benediktsson R, Hinney A, Hansen T, Andersen G, Borch-Johnsen K, Jorgensen T, Schäfer H, Faruque M, Doumatey A, Zhou J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Sigurdsson G, Hebebrand J, Pedersen O, Thorsteinsdottir U, Gulcher JR, Kong A, Rotimi C, Stefánsson K 2007 Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat Genet 39:218-225
-
(2007)
Nat Genet
, vol.39
, pp. 218-225
-
-
Helgason, A.1
Pálsson, S.2
Thorleifsson, G.3
Grant, S.F.4
Emilsson, V.5
Gunnarsdottir, S.6
Adeyemo, A.7
Chen, Y.8
Chen, G.9
Reynisdottir, I.10
Benediktsson, R.11
Hinney, A.12
Hansen, T.13
Andersen, G.14
Borch-Johnsen, K.15
Jorgensen, T.16
Schäfer, H.17
Faruque, M.18
Doumatey, A.19
Zhou, J.20
Wilensky, R.L.21
Reilly, M.P.22
Rader, D.J.23
Bagger, Y.24
Christiansen, C.25
Sigurdsson, G.26
Hebebrand, J.27
Pedersen, O.28
Thorsteinsdottir, U.29
Gulcher, J.R.30
Kong, A.31
Rotimi, C.32
Stefánsson, K.33
more..
-
19
-
-
54049088180
-
The transcription factor 7-like 2 gene and increased risk of type 2 diabetes: An update
-
Lyssenko V 2008 The transcription factor 7-like 2 gene and increased risk of type 2 diabetes: an update. Curr Opin Clin Nutr Metab Care 11:385-392
-
(2008)
Curr Opin Clin Nutr Metab Care
, vol.11
, pp. 385-392
-
-
Lyssenko, V.1
-
20
-
-
33847014094
-
Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans
-
Lehman DM, Hunt KJ, Leach RJ, Hamlington J, Arya R, Abboud HE, Duggirala R, Blangero J, Göring HH, Stern MP 2007 Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans. Diabetes 56:389-393
-
(2007)
Diabetes
, vol.56
, pp. 389-393
-
-
Lehman, D.M.1
Hunt, K.J.2
Leach, R.J.3
Hamlington, J.4
Arya, R.5
Abboud, H.E.6
Duggirala, R.7
Blangero, J.8
Göring, H.H.9
Stern, M.P.10
|