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Volumn 29, Issue 10, 2010, Pages 1818-1825

Why observational studies should be among the tools used in comparative effectiveness research

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COMPARATIVE EFFECTIVENESS; METHODOLOGY; OBSERVATION; UNITED STATES;

EID: 79951684079     PISSN: 02782715     EISSN: 15445208     Source Type: Journal    
DOI: 10.1377/hlthaff.2010.0666     Document Type: Article
Times cited : (172)

References (36)
  • 1
    • 84872258624 scopus 로고    scopus 로고
    • US Department of Health and Human Services, Federal Coordinating Council for Comparative Effectiveness Research. Report to the president and the Congress [Internet]. Washington (DC): HHS; 2009 Jun 30 [cited 2010 Aug 27]. Available from
    • US Department of Health and Human Services, Federal Coordinating Council for Comparative Effectiveness Research. Report to the president and the Congress [Internet]. Washington (DC): HHS; 2009 Jun 30 [cited 2010 Aug 27]. Available from: http://www.hhs.gov/recovery/programs/cer/cerannualrpt.pdf
  • 2
    • 84872233455 scopus 로고    scopus 로고
    • Patient Protection and Affordable Care Act of 2010, PL 111-148, sec. 6301
    • Patient Protection and Affordable Care Act of 2010, PL 111-148, sec. 6301.
  • 3
    • 77955752863 scopus 로고    scopus 로고
    • Comparative effectiveness research: methods development and research infrastructure
    • Tunis S, Benner J, McClellan M. Comparative effectiveness research: methods development and research infrastructure. Stat Med. 2010; 29(19):1963-76.
    • (2010) Stat Med. , vol.29 , Issue.19 , pp. 1963-1976
    • Tunis, S.1    Benner, J.2    Mcclellan, M.3
  • 4
    • 0141684982 scopus 로고    scopus 로고
    • Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy
    • Tunis SR, Stryker DB, Clancy CM. Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy. JAMA. 2003;290:1624-32.
    • (2003) JAMA. , vol.290 , pp. 1624-1632
    • Tunis, S.R.1    Stryker, D.B.2    Clancy, C.M.3
  • 5
    • 77952987298 scopus 로고    scopus 로고
    • Using science to improve the nation's health system: NIH's commitment to comparative effectiveness research
    • Lauer MS, Collins FS. Using science to improve the nation's health system: NIH's commitment to comparative effectiveness research. JAMA. 2010;303:2182-3.
    • (2010) JAMA. , vol.303 , pp. 2182-2183
    • Lauer, M.S.1    Collins, F.S.2
  • 6
    • 41549117102 scopus 로고    scopus 로고
    • Observational research, randomized trials and two views of medical science
    • Vandenbroucke JP. Observational research, randomized trials and two views of medical science. PLoS Med. 2008;5:0339-43.
    • (2008) PLoS Med. , vol.5 , pp. 0339-0343
    • Vandenbroucke, J.P.1
  • 7
    • 84872225293 scopus 로고    scopus 로고
    • To access the Technical Appendix, click on the Technical Appendix link in the box to the right of the article online
    • To access the Technical Appendix, click on the Technical Appendix link in the box to the right of the article online.
  • 8
    • 12844267573 scopus 로고    scopus 로고
    • Comparative effectiveness: asking the right questions, choosing the right method
    • Teutsch SM, Berger ML, Weinstein MC. Comparative effectiveness: asking the right questions, choosing the right method. Health Aff (Millwood). 2005;24(1):128-32.
    • (2005) Health Aff (Millwood). , vol.24 , Issue.1 , pp. 128-132
    • Teutsch, S.M.1    Berger, M.L.2    Weinstein, M.C.3
  • 9
    • 57649198083 scopus 로고    scopus 로고
    • De testimonio: on the evidence for decisions about the use of therapeutic interventions
    • Rawlins M. De testimonio: on the evidence for decisions about the use of therapeutic interventions. Lancet. 2008;372:2152-61.
    • (2008) Lancet. , vol.372 , pp. 2152-2161
    • Rawlins, M.1
  • 10
    • 68249130994 scopus 로고    scopus 로고
    • Rethinking randomized clinical trials for comparative effectiveness research: the need for transformational change
    • Luce BR, Kramer JM, Goodman SN, Connor JT, Tunis S, Whicher D, et al. Rethinking randomized clinical trials for comparative effectiveness research: the need for transformational change. Ann Intern Med. 2009;151(3):206-9.
    • (2009) Ann Intern Med. , vol.151 , Issue.3 , pp. 206-209
    • Luce, B.R.1    Kramer, J.M.2    Goodman, S.N.3    Connor, J.T.4    Tunis, S.5    Whicher, D.6
  • 11
    • 0034643512 scopus 로고    scopus 로고
    • Conventional-dose chemotherapy compared with high-dose chemotherapy plus autologous hematopoietic stem-cell transplantation for metastatic breast cancer
    • Stadtmauer EA, O'Neill A, Goldstein LJ, Crilley PA, Mangan KF, Ingle JN, et al. Conventional-dose chemotherapy compared with high-dose chemotherapy plus autologous hematopoietic stem-cell transplantation for metastatic breast cancer. N Engl J Med. 2000;342:1069-76.
    • (2000) N Engl J Med. , vol.342 , pp. 1069-1076
    • Stadtmauer, E.A.1    O'neill, A.2    Goldstein, L.J.3    Crilley, P.A.4    Mangan, K.F.5    Ingle, J.N.6
  • 12
    • 39749090590 scopus 로고    scopus 로고
    • Mortality benefit from unrestricted access to clopidogrel: too good to be true?
    • Suissa S. Mortality benefit from unrestricted access to clopidogrel: too good to be true? CMAJ. 2008;178:425-7.
    • (2008) CMAJ. , vol.178 , pp. 425-427
    • Suissa, S.1
  • 13
    • 84871471904 scopus 로고    scopus 로고
    • Institute of Medicine, Washington (DC): National Academies Press; 2009 Jun [cited 2010 May 12]. Available from
    • Institute of Medicine. Initial national priorities for comparative effectiveness research: report brief [Internet]. Washington (DC): National Academies Press; 2009 Jun [cited 2010 May 12]. Available from: http://www.iom.edu/Reports/2009/ComparativeEffectivenessResearchPriorities.aspx
    • Initial national priorities for comparative effectiveness research: report brief [Internet]
  • 14
    • 77953626306 scopus 로고    scopus 로고
    • Association of corticosteroid dose and route of administration with risk of treatment failure in acute exacerbation of chronic obstructive pulmonary disease
    • Lindenauer PK, Pekow PS, Lahti MC, Lee Y, Benjamin EM, Rothberg MB. Association of corticosteroid dose and route of administration with risk of treatment failure in acute exacerbation of chronic obstructive pulmonary disease. JAMA. 2010: 303(23):2359-67.
    • (2010) JAMA. , vol.303 , Issue.23 , pp. 2359-2367
    • Lindenauer, P.K.1    Pekow, P.S.2    Lahti, M.C.3    Lee, Y.4    Benjamin, E.M.5    Rothberg, M.B.6
  • 15
    • 77953638697 scopus 로고    scopus 로고
    • Acting on comparative effectiveness research in COPD
    • Krishnan JA, Mularski RA. Acting on comparative effectiveness research in COPD. JAMA. 2010;303(23): 2409-10.
    • (2010) JAMA. , vol.303 , Issue.23 , pp. 2409-2410
    • Krishnan, J.A.1    Mularski, R.A.2
  • 16
    • 68149123409 scopus 로고    scopus 로고
    • Impact of asthma controller medications on clinical, economic and patientreported outcomes
    • Tan H, Sarawate C, Singer J, Elward K, Cohen RI, Smart BA, et al. Impact of asthma controller medications on clinical, economic and patientreported outcomes. Mayo Clin Proc. 2009;84(8):675-84.
    • (2009) Mayo Clin Proc. , vol.84 , Issue.8 , pp. 675-684
    • Tan, H.1    Sarawate, C.2    Singer, J.3    Elward, K.4    Cohen, R.I.5    Smart, B.A.6
  • 17
    • 84872222773 scopus 로고    scopus 로고
    • HealthCore [Internet], Press release, HealthCore study reports that compliant patients have better results with inhaled corticosteroids; 2009 Aug 26 [cited 2010 Jul 23]. Available from
    • HealthCore [Internet].Wilmington (DE): HealthCore; c2009. Press release, HealthCore study reports that compliant patients have better results with inhaled corticosteroids; 2009 Aug 26 [cited 2010 Jul 23]. Available from: http://www.drugs.com/clinical_trials/comparativeeffectiveness-research-studymayo-clinic-proceedingsdemonstrated-asthma-patients-had-7960.html
    • (2009) Wilmington (DE): HealthCore
  • 18
    • 65249090204 scopus 로고    scopus 로고
    • Association of physician certification and outcomes among patients receiving an implantable cardioverter-defibrillator
    • Curtis JP, Luebbert JJ, Wang Y, Rathore SS, Chen J, Heidenreich PA, et al. Association of physician certification and outcomes among patients receiving an implantable cardioverter-defibrillator. JAMA. 2009;301:1661-70.
    • (2009) JAMA. , vol.301 , pp. 1661-1670
    • Curtis, J.P.1    Luebbert, J.J.2    Wang, Y.3    Rathore, S.S.4    Chen, J.5    Heidenreich, P.A.6
  • 19
    • 0141765805 scopus 로고    scopus 로고
    • Sirolimuseluting stents versus standard stents in patients with stenosis in a native coronary artery
    • Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, Shaughnessy CO, et al. Sirolimuseluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003;349:1315-23.
    • (2003) N Engl J Med. , vol.349 , pp. 1315-1323
    • Moses, J.W.1    Leon, M.B.2    Popma, J.J.3    Fitzgerald, P.J.4    Holmes, D.R.5    Shaughnessy, C.O.6
  • 21
    • 33847707734 scopus 로고    scopus 로고
    • Stent thrombosis redux: the FDA perspective
    • Farb A, Boam AS. Stent thrombosis redux: the FDA perspective. N Engl J Med. 2007;356:984-7.
    • (2007) N Engl J Med. , vol.356 , pp. 984-987
    • Farb, A.1    Boam, A.S.2
  • 22
    • 34147176083 scopus 로고    scopus 로고
    • Stent thrombosis late after implantation of first-generation drug-eluting stents: a cause for concern
    • Camenzind E, Steg PG, Wijns W. Stent thrombosis late after implantation of first-generation drug-eluting stents: a cause for concern. Circulation. 2007;115:1440-55.
    • (2007) Circulation. , vol.115 , pp. 1440-1455
    • Camenzind, E.1    Steg, P.G.2    Wijns, W.3
  • 26
    • 33847167065 scopus 로고    scopus 로고
    • Early and late coronary stent thrombosis of Sirolimus-eluting and Paclitaxeleluting stents in routine clinical practice: data from a large twoinstitutional cohort study
    • Daemen J, Wenaweser P, Tsuchida K, Abrecht L, Vaina S, Morder C. Early and late coronary stent thrombosis of Sirolimus-eluting and Paclitaxeleluting stents in routine clinical practice: data from a large twoinstitutional cohort study. Lancet. 2007;369:667-8.
    • (2007) Lancet. , vol.369 , pp. 667-668
    • Daemen, J.1    Wenaweser, P.2    Tsuchida, K.3    Abrecht, L.4    Vaina, S.5    Morder, C.6
  • 27
    • 84872249806 scopus 로고    scopus 로고
    • Food and Drug Administration. Update to FDA statement on coronary drug-eluting stents January 4, 2007. MedSun [serial on the Internet]. 2007 Jan 11 [cited 2010 Sep 16]. Available from
    • Food and Drug Administration. Update to FDA statement on coronary drug-eluting stents January 4, 2007. MedSun [serial on the Internet]. 2007 Jan 11 [cited 2010 Sep 16]. Available from: http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/medsun/news/printer.cfm?id=575
  • 28
    • 34248376428 scopus 로고    scopus 로고
    • Clinical outcomes and stent throm-bosis following off-label use of drugeluting stents
    • Win HK, Caldera AE, Maresh K, Lopez J, Rihal CS, Parikh MA, et al. Clinical outcomes and stent throm-bosis following off-label use of drugeluting stents. JAMA. 2007;297(18): 2001-9.
    • (2007) JAMA. , vol.297 , Issue.18 , pp. 2001-2009
    • Win, H.K.1    Caldera, A.E.2    Maresh, K.3    Lopez, J.4    Rihal, C.S.5    Parikh, M.A.6
  • 30
    • 70350776531 scopus 로고    scopus 로고
    • Good research practices for comparative effectiveness research: defining, reporting, and interpreting nonrandomized studies of treatment effects using secondary data sources: the ISPOR Good Research Practices for Retrospective Database Analysis Task Force report- part I
    • Berger ML, Mamdani M, Atkins D, Johnson ML. Good research practices for comparative effectiveness research: defining, reporting, and interpreting nonrandomized studies of treatment effects using secondary data sources: the ISPOR Good Research Practices for Retrospective Database Analysis Task Force report- part I. Value Health. 2009;12: 1044-61.
    • (2009) Value Health. , vol.12
    • Berger, M.L.1    Mamdani, M.2    Atkins, D.3    Johnson, M.L.4
  • 31
    • 70350780206 scopus 로고    scopus 로고
    • Good research practices for comparative effectiveness research: approaches to mitigate bias and confounding in the design of nonrandomized studies of treatment effects using secondary sources: the International Society for Pharmacoeconomics and Outcome Research Good Research Practices for Retrospective Analysis Task Force report-part II
    • Cox E, Martin BC, Van Staa T, Garbe E, Siebert U, Johnson ML. Good research practices for comparative effectiveness research: approaches to mitigate bias and confounding in the design of nonrandomized studies of treatment effects using secondary sources: the International Society for Pharmacoeconomics and Outcome Research Good Research Practices for Retrospective Analysis Task Force report-part II. Value Health. 2009;12:1053-61.
    • (2009) Value Health. , vol.12 , pp. 1053-1061
    • Cox, E.1    Martin, B.C.2    Van Staa, T.3    Garbe, E.4    Siebert, U.5    Johnson, M.L.6
  • 32
    • 70350776529 scopus 로고    scopus 로고
    • Good research practices for comparative effectiveness research: analytic methods to improve causal inference from nonrandomized studies of treatment effects using secondary data sources: the ISPOR Good Research Practices for Retrospective Database Analysis Task Force report-part III
    • Johnson ML, Crown W, Martin BC, Dormuth CR, Siebert U. Good research practices for comparative effectiveness research: analytic methods to improve causal inference from nonrandomized studies of treatment effects using secondary data sources: the ISPOR Good Research Practices for Retrospective Database Analysis Task Force report-part III. Value Health. 2009;12:1062-72.
    • (2009) Value Health. , vol.12 , pp. 1062-1072
    • Johnson, M.L.1    Crown, W.2    Martin, B.C.3    Dormuth, C.R.4    Siebert, U.5
  • 33
    • 84872235641 scopus 로고    scopus 로고
    • Making observational studies count: shaping the future of comparative effectiveness research
    • Dreyer NA. Making observational studies count: shaping the future of comparative effectiveness research. Epidemiology. Forthcoming.
    • Epidemiology. Forthcoming
    • Dreyer, N.A.1
  • 35
    • 31344462100 scopus 로고    scopus 로고
    • Extra scrutiny for industry funded trials: JAMA's demand for an additional hurdle is unfair-and absurd
    • Rothman KJ, Evans S. Extra scrutiny for industry funded trials: JAMA's demand for an additional hurdle is unfair-and absurd. BMJ. 2005;330: 1350-1.
    • (2005) BMJ. , vol.330 , pp. 1350-1351
    • Rothman, K.J.1    Evans, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.