Investigations on parotid gland recovery after IMRT in head and neck tumor patients

Strahlentherapie und Onkologie

Volumn 186, Issue 12, 2010, Pages 665-671

  Stock, Markus ^a   Dörr, Wolfgang ^a,b   Stromberger, Carmen ^a   Mock, Ulrike ^a   Koizar, Susanne ^a   Pötter, Richard ^a   Georg, Dietmar ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Head and neck; IMRT; Parotid gland; Scintigraphy; Xerostomia

Indexed keywords

CISPLATIN; FLUOROURACIL; MITOMYCIN C;

ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; CONVALESCENCE; DOSIMETRY; FEMALE; HEAD AND NECK TUMOR; HISTOGRAM; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MALE; MOUTH CANCER; ORGAN SIZE; OROPHARYNX CANCER; PAROTID GLAND; PAROTID GLAND FUNCTION; PAROTID GLAND SCINTIGRAPHY; RADIATION DOSE; SCINTIGRAPHY; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT PLANNING;

ADULT; AGED; AGED, 80 AND OVER; CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; NEOADJUVANT THERAPY; NEOPLASM STAGING; OROPHARYNGEAL NEOPLASMS; PAROTID GLAND; RADIATION INJURIES; RADIONUCLIDE IMAGING; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; RADIOTHERAPY, INTENSITY-MODULATED; SALIVATION; SODIUM PERTECHNETATE TC 99M; XEROSTOMIA; YOUNG ADULT;

EID: 79951681945     PISSN: 01797158     EISSN: 1439099X     Source Type: Journal    
DOI: 10.1007/s00066-010-2157-7     Document Type: Article

References (35)

1. Barker JL, Garden AS, Ang KK, et al. Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-andneck cancer using an integrated CT/linear accelerator system. Int J Radiat Oncol Biol Phys 2004;59:960-70. (Pubitemid 38834288)
2. Beer KT, Zehnder D, Lussi A, Greiner RH. Sparing of contralateral major salivary glands has a significant effect on oral health in patients treated with radical radiotherapy of head and neck tumors. Strahlenther Onkol 2002;178:722-6. (Pubitemid 35470268)
3. Bohuslavizki KH, Brenner W, Klutmann S, et al. Implementation and indications for quantitative sialoscintigraphy. Laryngorhinootologie 1997;76: 614-24.
4. Bussels B, Maes A, Flamen P, et al. Dose-response relationships within the parotid gland after radiotherapy for head and neck cancer. Radiother Oncol 2004;73:297-306. (Pubitemid 39601077)
5. Chao KS, Deasy JO, Markman J, et al. A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensitymodulated or three-dimensional radiation therapy: initial results. Int J Radiat Oncol Biol Phys 2001;49(4):907-16. (Pubitemid 32184597)
6. Cooper JS, Fu K, Marks J, et al. Late effects of radiation therapy in the head and neck region. Int J Radiat Oncol Biol Phys 1995;31:1141-1164.
7. Deasy JO, Moiseenko V, Marks L, et al. Radiotherapy dose-volume effects on salivary gland function. Int J Radiat Oncol Biol Phys 2010;76(Suppl): S58-S64.
8. Delana A, Menegotti L, Bolner A, et al. Impact of residual setup error on parotid gland dose in intensity-modulated radiation therapy with or without planning organ-at-risk margin. Strahlenther Onkol 2009;185:453-9.
9. Eisbruch A, Ship JA, Dawson LA, et al. Salivary gland sparing and improved target irradiation by conformal and intensity modulated irradiation of head and neck cancer. World J Surg 2003;27:832-7. (Pubitemid 37022398)
10. Eisbruch A, Ten Haken RK, Kim HM, et al. Dose, volume, and function relationships in parotid salivary glands following conformal and intensitymodulated irradiation of head and neck cancer. Int J Radiat Oncol Biol Phys 1999;45:577-87. (Pubitemid 29462636)
11. Georg D, Bogner J, Dieckmann K, Pötter R. Is mask-based stereotactic headand- neck fixation as precise as stereotactic head fixation for precision radiotherapy? Int J Radiat Oncol Biol Phys 2006;66(4 Suppl):561-566.
12. Georg D, Georg P, Hillbrand M, et al. Assessment of improved organ at risk sparing for advanced cervix carcinoma utilizing precision radiotherapy techniques. Strahlenther Onkol 2008;184:586-91.
13. Georg D, Kroupa B, Georg P, et al. Inverse planning-a comparative intersystem and interpatient constraint study. Strahlenther Onkol 2006; 182:473-80. (Pubitemid 44214491)
14. Gregoire V, Levendag P, Ang KK, et al. CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC,RTOG consensus guidelines. Radiother Oncol 2003; 69:227-36. (Pubitemid 37485996)
15. Guerrero Urbano MT, Clark CH, Kong C, et al. Target volume definition for head and neck intensity modulated radiotherapy: pre-clinical evaluation of PARSPORT trial guidelines. Clin Oncol (R Coll Radiol) 2007;19:604-13. (Pubitemid 47308656)
16. Hey J, Setz J, Gerlach R, et al. Parotid-gland-sparing 3D conformal radiotherapy in patients with bilateral radiotherapy of the head and neck region - results in clinical practice. Oral Oncol 2009;45:e11-7.
17. Hsiung CY, Ting HM, Huang HY, et al. Parotid-sparing intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma: Preserved parotid function after IMRT on quantitative salivary scintigraphy, and comparison with historical data after conventional radiotherapy. Int J Radiat Oncol Biol Phys 2006;66:454-461.
18. Kuhnt T, Janich M, Götz U, et al. Presentation of a 3D conformal radiotherapy technique for head-and-neck tumors resulting in substantial protection of the parotid glands. Strahlenther Onkol 2006;182(6):325-30. (Pubitemid 43727350)
19. Kuhnt T, Jirsak N, M?ller AC, et al. Quantitative and qualitative investigations of salivary gland function in dependence on irradiation dose and volume for reduction of xerostomia in patients with head-and-neck cancer. Strahlenther Onkol 2005;181:520-8. (Pubitemid 41059522)
20. Kwong DL, Pow EH, Sham JS, et al. Intensity-modulated radiotherapy for early-stage nasopharyngeal carcinoma: a prospective study on disease control and preservation of salivary function. Cancer 2004;101:1584-93. (Pubitemid 39318905)
21. Lee C, Langen KM, Lu W, et al. Evaluation of geometric changes of parotid glands during head and neck cancer radiotherapy using daily MVCT and automatic deformable registration. Radiother Oncol 2008;89:81-88.
22. Li C, Taylor JMG, Ten Haken RK, et al. The impact of dose on parotid salivary recovery in head and neck cancer patients treated with radiation therapy. Int J Radiat Oncol Biol Phys 2007;67:660-9. (Pubitemid 46215864)
23. Lin KK, Pajak TF, Trotti A, et al. A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003. Int J Radiat Oncol Biol Phys 2000;48:7-16. (Pubitemid 30488207)
24. Marzi S, Iaccarino G, Pasciuti K, et al. Analysis of salivary flow and dosevolume modeling of complication incidence in patients with head-and-neck cancer receiving intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 2009;73:1252-9.
25. M?nter MW, Karger CP, Hoffner SG, et al. Evaluation of salivary gland function after treatment of head-and-neck tumors with intensity-modulated radiotherapy by quantitative pertechnetate scintigraphy. Int J Radiat Oncol Biol Phys 2004;58:175-84. (Pubitemid 38010351)
26. Nutting C, A?Hern R, Rogers MS, et al. First results of a phase III multicenter randomized controlled trial of intensity modulated (IMRT) versus conventional radiotherapy (RT) in head and neck cancer (PARSPORT: ISRCTN48243537; CRUK/03/005). J Clin Oncol 2009;27(suppl):18s (abstr LBA6006).
27. Ortholan C, Chamorey E, Benezery K, et al. Modeling of salivary production recovery after radiotherapy using mixed models: Determination of optimal dose constraint for IMRT planning and construction of convenient tools to predict salivary function. Int J Radiat Oncol Biol Phys 2009;73:178-86.
28. Pacholke HD, Amdur RJ, Morris CG, et al. Late xerostomia after intensitymodulated radiation therapy versus conventional radiotherapy. Am J Clin Oncol 2005;28:351-8. (Pubitemid 41099539)
29. Pow EHN, Kwong DLW, McMillan AS, et al. Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: initial report on a randomized controlled clinical trial. Int J Radiat Oncol Biol Phys 2001;66:981-91. (Pubitemid 44633504)
30. Rades D, Stoehr M, Meyners T, et al. Evaluation of prognostic factors and two radiation techniques in patients treated with surgery followed by radio(chemo)therapy or definitive radio(chemo)therapy for locally advanced head-and-neck cancer. Strahlenther Onkol 2008;184:198-205. (Pubitemid 351508132)
31. Roesink JM, Moerland MA, Hoekstra A, et al. Scintigraphic assessment of early and late parotid gland function after radiotherapy for head-and-neck cancer: A prospective study of dose-volume response relationships. Int J Radiat Oncol Biol Phys 2004;58:1451-60. (Pubitemid 38438307)
32. SAS Institute Inc., Cary, NC, SAS/STAT Users Guide Version 6. 1990.
33. Voordeckers M, Everaert H, Tournel K, et al. Longitudinal assessment of parotid function in patients receiving tomotherapy for head-and-neck cancer. Strahlenther Onkol 2008;184:400-5.
34. Wiggenraad R, Mast M, van Santvoort J, et al. ConPas: a 3-D conformal parotid gland-sparing irradiation technique for bilateral neck treatment as an alternative to IMRT. Strahlenther Onkol 2005;181:673-82. (Pubitemid 41437264)
35. Wilkens JJ, Alaly JR, Zakarian K, et al. IMRT treatment planning based on prioritizing prescription goals. Phys Med Biol 2007;52:1675-92. (Pubitemid 46646374)