메뉴 건너뛰기




Volumn 35, Issue 2, 2011, Pages 198-207

Estrogen inhibits NPY secretion through membrane-associated estrogen receptor (ER)-α in clonal, immortalized hypothalamic neurons

Author keywords

AMPK; estrogen; estrogen receptor ; feeding; neuropeptide Y; PI3K

Indexed keywords

1,3,5 TRIS(4 HYDROXYPHENYL) 4 PROPYLPYRAZOLE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 2,3 BIS(4 HYDROXYPHENYL) PROPIONITRILE; CAVEOLIN 1; CHRYSENE; DORSOMORPHIN DIHYDROCHLORIDE; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METHYL PIPERIDINO PYRAZOLE; MITOGEN ACTIVATED PROTEIN KINASE; NEUROPEPTIDE Y; PHOSPHATIDYLINOSITOL 3 KINASE; PROPIONITRILE; PYRAZOLE; R,R TETRAHYDROCHRYSENE; UNCLASSIFIED DRUG; UO 126;

EID: 79951671672     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2010.124     Document Type: Article
Times cited : (56)

References (33)
  • 3
    • 0034071592 scopus 로고    scopus 로고
    • Effect of long-term ovariectomy and estrogen replacement on the expression of estrogen receptor gene in female rats
    • Mohamed MK, Abdel-Rahman AA. Effect of long-term ovariect-omy and estrogen replacement on the expression of estrogen receptor gene in female rats. Eur J Endocrinol 2000; 142: 307-314. (Pubitemid 30176942)
    • (2000) European Journal of Endocrinology , vol.142 , Issue.3 , pp. 307-314
    • Mohamed, M.K.1    Abdel-Rahman, A.A.2
  • 5
    • 0026347185 scopus 로고
    • Postmeno-pausal hormone replacement therapy prevents central distri-bution of body fat after menopause
    • Haarbo J, Marslew U, Gotfredsen A, Christiansen C. Postmeno-pausal hormone replacement therapy prevents central distri-bution of body fat after menopause. Metabolism 1991; 40: 1323-1326.
    • (1991) Metabolism , vol.40 , pp. 1323-1326
    • Haarbo, J.1    Marslew, U.2    Gotfredsen, A.3    Christiansen, C.4
  • 6
    • 0026563288 scopus 로고
    • Effects of in vivo estrogen treatment on adipose tissue metabolism and nuclear estrogen receptor binding in isolated rat adipocytes
    • Pedersen SB, Borglum JD, Moller-Pedersen T, Richelsen B. Effects of in vivo estrogen treatment on adipose tissue metabolism and nuclear estrogen receptor binding in isolated rat adipocytes. Mol Cell Endocrinol 1992; 85: 13-19.
    • (1992) Mol Cell Endocrinol , vol.85 , pp. 13-19
    • Pedersen, S.B.1    Borglum, J.D.2    Moller-Pedersen, T.3    Richelsen, B.4
  • 8
    • 43849093153 scopus 로고    scopus 로고
    • Estradiol decreases the orexigenic effect of neuropeptide Y, but not agouti-related protein, in ovariectomized rats
    • Santollo J, Eckel LA. Estradiol decreases the orexigenic effect of neuropeptide Y, but not agouti-related protein, in ovariectomized rats. Behav Brain Res 2008; 191: 173-177.
    • (2008) Behav Brain Res , vol.191 , pp. 173-177
    • Santollo, J.1    Eckel, L.A.2
  • 9
    • 0028318098 scopus 로고
    • Anorectic effects of estrogen may be mediated by decreased neuropeptide-Y release in the hypothalamic paraventricular nucleus
    • DOI 10.1210/en.134.6.2367
    • Bonavera JJ, Dube MG, Kalra PS, Kalra SP. Anorectic effects of estrogen may be mediated by decreased neuropeptide-Y release in the hypothalamic paraventricular nucleus. Endocrinology 1994; 134: 2367-2370. (Pubitemid 24170844)
    • (1994) Endocrinology , vol.134 , Issue.6 , pp. 2367-2370
    • Bonavera, J.J.1    Dube, M.G.2    Kalra, P.S.3    Kalra, S.P.4
  • 10
    • 34248661568 scopus 로고    scopus 로고
    • Oestrogenic regulation of pro-opiomelanocortin, neuropeptide Y and corticotrophin-releasing hormone mRNAs in mouse hypothalamus
    • DOI 10.1111/j.1365-2826.2007.01548.x
    • Pelletier G, Li S, Luu-The V, Labrie F. Oestrogenic regulation of pro-opiomelanocortin, neuropeptide Y and corticotrophin-releas-ing hormone mRNAs in mouse hypothalamus. J Neuroendocrinol 2007; 19: 426-431. (Pubitemid 46774034)
    • (2007) Journal of Neuroendocrinology , vol.19 , Issue.6 , pp. 426-431
    • Pelletier, G.1    Li, S.2    Luu-The, V.3    Labrie, F.4
  • 12
    • 0022873040 scopus 로고
    • Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity
    • DOI 10.1016/0196-9781(86)90149-X
    • Stanley BG, Kyrkouli S, Lampert S, Leibowitz S. Neuropeptide Y chronically injected into the hypothalamus: a powerful neuro-chemical inducer of hyperphagia and obesity. Peptides 1986; 7: 1189-1192. (Pubitemid 17226746)
    • (1986) Peptides , vol.7 , Issue.6 , pp. 1189-1192
    • Stanley, B.G.1    Kyrkouli, S.E.2    Lampert, S.3    Leibowitz, S.F.4
  • 13
  • 14
    • 0021248888 scopus 로고
    • Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats
    • Clark JT, Kalra PS, Crowley WR, Kalra SP. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 1984; 115: 427-429. (Pubitemid 14086844)
    • (1984) Endocrinology , vol.115 , Issue.1 , pp. 427-429
    • Clark, J.T.1    Kalra, P.S.2    Crowley, W.R.3    Kalra, S.P.4
  • 15
    • 0023759108 scopus 로고
    • Evidence that NPY-containing neurons in the brainstem project into selected hypothalamic nuclei: Implication in feeding behavior
    • Sahu A, Kalra SP, Crowley WR, Kalra PS. Evidence that NPY-containing neurons in the brainstem project into selected hypothalamic nuclei: implication in feeding behavior. Brain Res 1988; 9: 376-378.
    • (1988) Brain Res , vol.9 , pp. 376-378
    • Sahu, A.1    Kalra, S.P.2    Crowley, W.R.3    Kalra, P.S.4
  • 16
    • 0030562069 scopus 로고    scopus 로고
    • Estrogen increases hypothalamic neuropeptide Y (NPY) mRNA expression in ovariectomized obese rat
    • DOI 10.1016/0304-3940(96)12322-3
    • Shimizu H, Ohtani K, Kato Y, Tanaka Y, Mori M. Withdrawal of [corrected] estrogen increases hypothalamic neuropeptide Y (NPY) mRNA expression in ovariectomized obese rat Neurosci Lett 1996; 204: 81-84. (Pubitemid 26053679)
    • (1996) Neuroscience Letters , vol.204 , Issue.1-2 , pp. 81-84
    • Shimizu, H.1    Ohtani, K.-I.2    Kato, Y.3    Tanaka, Y.4    Mori, M.5
  • 17
    • 0347717868 scopus 로고    scopus 로고
    • Generation of a Phenotypic Array of Hypothalamic Neuronal Cell Models to Study Complex Neuroendocrine Disorders
    • DOI 10.1210/en.2003-0946
    • Belsham DD, Cai F, Cui H, Smukler SR, Salapatek AM, Shkreta L. Generation of a phenotypic array of hypothalamic neuronal cell models to study complex neuroendocrine disorders. Endocrinology 2004; 145: 393-400. (Pubitemid 38094535)
    • (2004) Endocrinology , vol.145 , Issue.1 , pp. 393-400
    • Belsham, D.D.1    Cai, F.2    Cui, H.3    Smukler, S.R.4    Salapatek, A.M.F.5    Shkreta, L.6
  • 18
    • 72749091486 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons
    • Belsham DD, Fick LJ, Dalvi PS, Centeno ML, Chalmers JA, Lee PK. et al. Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons. Faseb J 2009; 23: 4256-4265.
    • (2009) Faseb J , vol.23 , pp. 4256-4265
    • Belsham, D.D.1    Fick, L.J.2    Dalvi, P.S.3    Centeno, M.L.4    Chalmers, J.A.5    Lee, P.K.6
  • 19
    • 33747813597 scopus 로고    scopus 로고
    • Coordinate regulation of neuropeptide Y and agouti-related peptide gene expression by estrogen depends on the ratio of estrogen receptor (ER) α to ERβ in clonal hypothalamic neurons
    • DOI 10.1210/me.2006-0027
    • Titolo D, Cai F, Belsham DD. Coordinate regulation of neuropep-tide Y and agouti-related peptide gene expression by estrogen depends on the ratio of estrogen receptor (ER) alpha to ERbeta in clonal hypothalamic neurons. Mol Endocrinol 2006; 20: 2080-2092. (Pubitemid 44286706)
    • (2006) Molecular Endocrinology , vol.20 , Issue.9 , pp. 2080-2092
    • Titolo, D.1    Cai, F.2    Belsham, D.D.3
  • 20
    • 22144443539 scopus 로고    scopus 로고
    • Estrogen modulates endothelial and neuronal nitric oxide synthase expression via an estrogen receptor β-dependent mechanism in hypothalamic slice cultures
    • DOI 10.1210/en.2004-1375
    • Gingerich S, Krukoff TL. Estrogen modulates endothelial and neuronal nitric oxide synthase expression via an estrogen receptor beta-dependent mechanism in hypothalamic slice cultures. Endocrinology 2005; 146: 2933-2941. (Pubitemid 41002800)
    • (2005) Endocrinology , vol.146 , Issue.7 , pp. 2933-2941
    • Gingerich, S.1    Krukoff, T.L.2
  • 21
    • 33751082093 scopus 로고    scopus 로고
    • Estrogen in the paraventricular nucleus attenuates L-glutamate-induced increases in mean arterial pressure through estrogen receptor β and NO
    • DOI 10.1161/01.HYP.0000248754.67128.ff, PII 0000426820061200000023
    • Gingerich S, Krukoff TL. Estrogen in the paraventricular nucleus attenuates L-glutamate-induced increases in mean arterial pres-sure through estrogen receptor beta and NO. Hypertension 2006; 48: 1130-1136. (Pubitemid 44772718)
    • (2006) Hypertension , vol.48 , Issue.6 , pp. 1130-1136
    • Gingerich, S.1    Krukoff, T.L.2
  • 23
    • 46749087424 scopus 로고    scopus 로고
    • Estrogen facilitates both phosphatidylinositol 3-kinase/Akt and ERK1/2 mitogen-activated protein kinase membrane signal-ing required for long-term neuropeptide y transcriptional regulation in clonal, immortalized neurons
    • Titolo D, Mayer CM, Dhillon SS, Cai F, Belsham DD. Estrogen facilitates both phosphatidylinositol 3-kinase/Akt and ERK1/2 mitogen-activated protein kinase membrane signal-ing required for long-term neuropeptide Y transcriptional regulation in clonal, immortalized neurons. J Neurosci 2008; 28: 6473-6482.
    • (2008) J Neurosci , vol.28 , pp. 6473-6482
    • Titolo, D.1    Mayer, C.M.2    Dhillon, S.S.3    Cai, F.4    Belsham, D.D.5
  • 24
    • 0030727813 scopus 로고    scopus 로고
    • Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system
    • DOI 10.1002/(SICI)1096-9861(19971201)388:4<507::AID-CNE1>3.0.CO;2-6
    • Shughrue PJ, Lane MV, Merchenthaler I. Comparative distribu-tion of estrogen receptor-alpha and-beta mRNA in the rat central nervous system. J Comp Neurol 1997; 388: 507-525. (Pubitemid 27481288)
    • (1997) Journal of Comparative Neurology , vol.388 , Issue.4 , pp. 507-525
    • Shughrue, P.J.1    Lane, M.V.2    Merchenthaler, I.3
  • 25
    • 0031910162 scopus 로고    scopus 로고
    • Differential distribution and regulation of estrogen receptor-α and -β mRNA within the female rat brain
    • DOI 10.1016/S0169-328X(97)00351-3, PII S0169328X97003513
    • Osterlund M, Kuiper GG, Gustafsson JA, Hurd YL. Differential distribution and regulation of estrogen receptor-alpha and-beta mRNA within the female rat brain. Brain Res Mol Brain Res 1998; 54: 175-180. (Pubitemid 28119175)
    • (1998) Molecular Brain Research , vol.54 , Issue.1 , pp. 175-180
    • Osterlund, M.1    Kuiper, G.2    Gustafsson, J.-A.3    Hurd, Y.L.4
  • 26
    • 0036140032 scopus 로고    scopus 로고
    • Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis
    • DOI 10.1210/me.16.1.70
    • Filardo EJ, Quinn JA, Frackelton Jr AR, Bland KI. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol Endocrinol 2002; 16: 70-84. (Pubitemid 34044499)
    • (2002) Molecular Endocrinology , vol.16 , Issue.1 , pp. 70-84
    • Filardo, E.J.1    Quinn, J.A.2    Raymond Frackelton Jr., A.3    Bland, K.I.4
  • 27
    • 0001548401 scopus 로고    scopus 로고
    • Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: Studies of ERα and ERβ expressed in chinese hamster ovary cells
    • DOI 10.1210/me.13.2.307
    • Razandi M, Pedram A, Greene GL, Levin ER. Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells. Mol Endocrinol 1999; 13: 307-319. (Pubitemid 29068005)
    • (1999) Molecular Endocrinology , vol.13 , Issue.2 , pp. 307-319
    • Razandi, M.1    Pedram, A.2    Greene, G.L.3    Levin, E.R.4
  • 28
    • 0028925081 scopus 로고
    • Membrane estrogen receptors identified by multiple antibody labeling and impeded-ligand binding
    • Pappas TC, Gametchu B, Watson CS. Membrane estrogen receptors identified by multiple antibody labeling and impeded-ligand binding. Faseb J 1995; 9: 404-410.
    • (1995) Faseb J , vol.9 , pp. 404-410
    • Pappas, T.C.1    Gametchu, B.2    Watson, C.S.3
  • 31
    • 0033038418 scopus 로고    scopus 로고
    • Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
    • DOI 10.1210/er.20.1.68
    • Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 1999; 20: 68-100. (Pubitemid 29092036)
    • (1999) Endocrine Reviews , vol.20 , Issue.1 , pp. 68-100
    • Kalra, S.P.1    Dube, M.G.2    Pu, S.3    Xu, B.4    Horvath, T.L.5    Kalra, P.S.6
  • 32
    • 0031031251 scopus 로고    scopus 로고
    • Involvement of the medial preoptic area in the anorectic action of estrogens
    • Dagnault A, Richard D. Involvement of the medial preoptic area in the anorectic action of estrogens. Am JPhysiol 1997; 272: R311-R317.
    • (1997) Am JPhysiol , vol.272
    • Dagnault, A.1    Richard, D.2
  • 33
    • 0021681046 scopus 로고
    • Intracranial estradiol in ovariectomized guinea pigs: Effects on ingestive behaviors and body weight
    • DOI 10.1016/0006-8993(84)91178-8
    • Butera PC, Czaja JA. Intracranial estradiol in ovariectomized guinea pigs: effects on ingestive behaviors and body weight. Brain Res 1984; 322: 41-48. (Pubitemid 15215717)
    • (1984) Brain Research , vol.322 , Issue.1 , pp. 41-48
    • Butera, P.C.1    Czaja, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.