-
1
-
-
0035810148
-
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
-
DOI 10.1056/NEJM200104053441404
-
Joensuu H, Roberts PJ, Sarlomo-Rikala M, Andersson LC, Tervahartiala P, Tuveson D, Silberman S, Capdeville R, Dimitrijevic S, Druker B, Demetri GD: Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med 2001;344:1052-1056 (Pubitemid 32267975)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.14
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
Andersson, L.C.4
Tervahartiala, P.5
Tuveson, D.6
Silberman, S.L.7
Capdeville, R.8
Dimitrijevic, S.9
Druker, B.10
Demetri, G.D.11
-
2
-
-
0036305274
-
Clinical management of gastrointestinal stromal tumors: Before and after STI-571
-
DOI 10.1053/hupa.2002.124122
-
Dematteo RP, Heinrich MC, El-Rifai WM, Demetri G: Clinical management of gastrointestinal stromal tumors: Before and after STI-571. Hum Pathol 2002;33:466-477 (Pubitemid 34747865)
-
(2002)
Human Pathology
, vol.33
, Issue.5
, pp. 466-477
-
-
Dematteo, R.P.1
Heinrich, M.C.2
El-Rifai, W.M.3
Demetri, G.4
-
3
-
-
33749459756
-
Gastrointestinal stromal tumors: Review on morphology, molecular pathology, prognosis, and differential diagnosis
-
Miettinen M, Lasota J: Gastrointestinal stromal tumors review on morphology, molecular pathology, prognosis, and differential diagnosis. Arch Pathol Lab Med 2006;130:1466-1478 (Pubitemid 44520713)
-
(2006)
Archives of Pathology and Laboratory Medicine
, vol.130
, Issue.10
, pp. 1466-1478
-
-
Miettinen, M.1
Lasota, J.2
-
4
-
-
0031947592
-
Gastrointestinal pacemaker cell tumor (GIPACT): Gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal
-
Kindblom LG, Remotti HE, Aldenborg F, Meis-Kindblom JM: Gastrointestinal pacemaker cell tumor (GIPACT): Gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol 1998;152:1259-1269 (Pubitemid 28221878)
-
(1998)
American Journal of Pathology
, vol.152
, Issue.5
, pp. 1259-1269
-
-
Kindblom, L.-G.1
Remotti, H.E.2
Aldenborg, F.3
Meis-Kindblom, J.M.4
-
6
-
-
73949094832
-
BRAF mutation status in gastrointestinal stromal tumors
-
Hostein I, Faur N, Primois C, Boury F, Denard J, Emile JF, Bringuier PP, Scoazec JY, Coindre JM: BRAF mutation status in gastrointestinal stromal tumors. Am J Clin Pathol 2010;133:141-148
-
(2010)
Am J Clin Pathol
, vol.133
, pp. 141-148
-
-
Hostein, I.1
Faur, N.2
Primois, C.3
Boury, F.4
Denard, J.5
Emile, J.F.6
Bringuier, P.P.7
Scoazec, J.Y.8
Coindre, J.M.9
-
7
-
-
2742529418
-
Human protooncogene c-kit: A new cell surface receptor tyrosine kinase for an unidentified ligand
-
Yarden Y, Kuang WJ, Yang-Feng T, Coussens L, Munemitsu S, Dull TJ, Chen E, Schlessinger J, Francke U, Ullrich A: Human protooncogene c-kit: A new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J 1987;6:3341-3351
-
(1987)
EMBO J
, vol.6
, pp. 3341-3351
-
-
Yarden, Y.1
Kuang, W.J.2
Yang-Feng, T.3
Coussens, L.4
Munemitsu, S.5
Dull, T.J.6
Chen, E.7
Schlessinger, J.8
Francke, U.9
Ullrich, A.10
-
8
-
-
0025013548
-
Identification of a ligand for the c-kit protooncogene
-
Williams DE, Eisenman J, Baird A, Rauch C, Van Ness K, March CJ, Park LS, Martin U, Mochizuki DY, Boswell HS: Identification of a ligand for the c-kit protooncogene. Cell 1990;63:167-174
-
(1990)
Cell
, vol.63
, pp. 167-174
-
-
Williams, D.E.1
Eisenman, J.2
Baird, A.3
Rauch, C.4
Van Ness, K.5
March, C.J.6
Park, L.S.7
Martin, U.8
Mochizuki, D.Y.9
Boswell, H.S.10
-
9
-
-
0026480717
-
Requirement of c-kit for development of intestinal pacemaker system
-
Maeda H, Yamagata A, Nishikawa S, Yoshinaga K, Kobayashi S, Nishi K, Nishikawa S: Requirement of c-kit for development of intestinal pacemaker system. Development 1992;116:369-375
-
(1992)
Development
, vol.116
, pp. 369-375
-
-
Maeda, H.1
Yamagata, A.2
Nishikawa, S.3
Yoshinaga, K.4
Kobayashi, S.5
Nishi, K.6
Nishikawa, S.7
-
10
-
-
23944452835
-
KIT (CD117): A review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation
-
DOI 10.1097/01.pai.0000173054.83414.22
-
Miettinen M, Lasota J: KIT (CD117): A review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation. Appl Immunohistochem Mol Morphol 2005;13:205-220 (Pubitemid 41209013)
-
(2005)
Applied Immunohistochemistry and Molecular Morphology
, vol.13
, Issue.3
, pp. 205-220
-
-
Miettinen, M.1
Lasota, J.2
-
11
-
-
14344256167
-
PDGFRalpha- and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features
-
DOI 10.1111/j.1365-2559.2005.02061.x
-
Pauls K, Merkelbach-Bruse S, Thal D, Büttner R, Wardelmann E: PDGFRalpha- and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features. Histopathology 2005;46:166-175 (Pubitemid 40293015)
-
(2005)
Histopathology
, vol.46
, Issue.2
, pp. 166-175
-
-
Pauls, K.1
Merkelbach-Bruse, S.2
Thal, D.3
Buttner, R.4
Wardelmann, E.5
-
12
-
-
59149088969
-
Dotlike or Golgi-like KIT and PDGFRA staining in GIST
-
Emile JF, Stock N, Corless CL, Sciot R, Schildhaus HU, Brahimi S, Debiec-Rychter M, Wardelmann E, Coindre JM, Blay JY: Dotlike or Golgi-like KIT and PDGFRA staining in GIST. Am J Surg Pathol 2009;33:157-158
-
(2009)
Am J Surg Pathol
, vol.33
, pp. 157-158
-
-
Emile, J.F.1
Stock, N.2
Corless, C.L.3
Sciot, R.4
Schildhaus, H.U.5
Brahimi, S.6
Debiec-Rychter, M.7
Wardelmann, E.8
Coindre, J.M.9
Blay, J.Y.10
-
13
-
-
42649117800
-
PDGFRA immunostaining can help in the diagnosis of gastrointestinal stromal tumors
-
DOI 10.1097/PAS.0b013e31815c47e8
-
Miselli F, Millefanti C, Conca E, Negri T, Piacenza C, Pierotti MA, Tamborini E, Pilotti S: PDGFRA immunostaining can help in the diagnosis of gastrointestinal stromal tumors. Am J Surg Pathol 2008;32:738-743 (Pubitemid 351600827)
-
(2008)
American Journal of Surgical Pathology
, vol.32
, Issue.5
, pp. 738-743
-
-
Miselli, F.1
Millefanti, C.2
Conca, E.3
Negri, T.4
Piacenza, C.5
Pierotti, M.A.6
Tamborini, E.7
Pilotti, S.8
-
14
-
-
66149129912
-
Dotlike or Golgi-like KIT and PDGFRA staining in GIST
-
Negri T, Orsenigo, M, Conca E, Pierotti M, Tamborini E, Pilotti S: Dotlike or Golgi-like KIT and PDGFRA staining in GIST. Am J Surg Pathol 2009;33:158-159
-
(2009)
Am J Surg Pathol
, vol.33
, pp. 158-159
-
-
Negri, T.1
Orsenigo, M.2
Conca, E.3
Pierotti, M.4
Tamborini, E.5
Pilotti, S.6
-
15
-
-
3042711783
-
Role of KIT and platelet-derived growth factor receptors as oncoproteins
-
Fletcher JA: Role of KIT and platelet-derived growth factor receptors as oncoproteins. Semin Oncol (Suppl 6) 2004;31:4-11
-
(2004)
Semin Oncol
, vol.31
, Issue.SUPPL. 6
, pp. 4-11
-
-
Fletcher, J.A.1
-
16
-
-
35248849299
-
Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl
-
DOI 10.1016/j.yexcr.2007.08.021, PII S0014482707004065
-
Sun J, Pedersen M, Bengtsson S, Rönnstrand L: Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl. Exp Cell Res 2007;313:3935-3942 (Pubitemid 47561898)
-
(2007)
Experimental Cell Research
, vol.313
, Issue.18
, pp. 3935-3942
-
-
Sun, J.1
Pedersen, M.2
Bengtsson, S.3
Ronnstrand, L.4
-
17
-
-
70249090434
-
DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: A study of 1840 cases
-
Miettinen M, Wang ZF, Lasota J: DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: A study of 1840 cases. Am J Surg Pathol 2009;33:1401-1407
-
(2009)
Am J Surg Pathol
, vol.33
, pp. 1401-1407
-
-
Miettinen, M.1
Wang, Z.F.2
Lasota, J.3
-
18
-
-
20944446788
-
PDGFR expression in differential diagnosis between KIT-negative gastrointestinal stromal tumours and other primary soft-tissue tumours of the gastrointestinal tract
-
DOI 10.1111/j.1365-2559.2005.02128.x
-
Rossi G, Valli R, Bertolini F, Marchioni A, Cavazza A, Mucciarini C, Migaldi M, Federico M, Trentini GP, Sgambato A: PDGFR expression in differential diagnosis between KIT-negative gastrointestinal stromal tumours and other primary soft-tissue tumours of the gastrointestinal tract. Histopathology 2005;46:522-531 (Pubitemid 40632309)
-
(2005)
Histopathology
, vol.46
, Issue.5
, pp. 522-531
-
-
Rossi, G.1
Valli, R.2
Bertolini, F.3
Marchioni, A.4
Cavazza, A.5
Mucciarini, C.6
Migaldi, M.7
Federico, M.8
Trentini, G.P.9
Sgambato, A.10
-
19
-
-
45549090311
-
Characteristics of KIT-negative gastrointestinal stromal tumours and diagnostic utility of protein kinase C theta immunostaining
-
DOI 10.1136/jcp.2007.052225
-
Lee HE, Kim MA, Lee HS, Lee BL, Kim WH: Characteristics of KIT-negative gastrointestinal stromal tumours and diagnostic utility of protein kinase C theta immunostaining. J Clin Pathol 2008;61:722-729 (Pubitemid 351859964)
-
(2008)
Journal of Clinical Pathology
, vol.61
, Issue.6
, pp. 722-729
-
-
Lee, H.E.1
Kim, M.A.2
Lee, H.S.3
Lee, B.L.4
Kim, W.H.5
-
20
-
-
3442881363
-
Protein kinase C (PKC) expression and constitutive activation in gastrointestinal stromal tumors (GISTs)
-
Duensing A, Joseph NE, Medeiros F, Smith F, Hornick JL, Heinrich MC, Corless CL, Demetri GD, Fletcher CD, Fletcher JA: Protein kinase C (PKC) expression and constitutive activation in gastrointestinal stromal tumors (GISTs). Cancer Res 2004;64:5127-5131
-
(2004)
Cancer Res
, vol.64
, pp. 5127-5131
-
-
Duensing, A.1
Joseph, N.E.2
Medeiros, F.3
Smith, F.4
Hornick, J.L.5
Heinrich, M.C.6
Corless, C.L.7
Demetri, G.D.8
Fletcher, C.D.9
Fletcher, J.A.10
-
21
-
-
33750326338
-
PKCθ expression in gastrointestinal stromal tumor
-
DOI 10.1038/modpathol.3800673, PII 3800673
-
Kim KM, Kang DW, Moon WS, Park JB, Park CK, Sohn JH, Jeong JS, Cho MY, Jin SY, Choi JS, Kang DY: PKCθ expression in gastrointestinal stromal tumor. Mod Pathol 2006;19:1480-1486 (Pubitemid 44624168)
-
(2006)
Modern Pathology
, vol.19
, Issue.11
, pp. 1480-1486
-
-
Kim, K.-M.1
Kang, D.W.2
Moon, W.S.3
Park, J.B.4
Park, C.K.5
Sohn, J.H.6
Jeong, J.S.7
Cho, M.-Y.8
Jin, S.-Y.9
Choi, J.S.10
Kang, D.Y.11
-
22
-
-
46149104384
-
Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors
-
DOI 10.1073/pnas.0803383105
-
Tarn C, Rink L, Merkel E, Flieder D, Pathak H, Koumbi D, Testa JR, Eisenberg B, von Mehren M, Godwin AK: Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors. PNAS 2008;105:8387-8392 (Pubitemid 351904765)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.24
, pp. 8387-8392
-
-
Tarn, C.1
Rink, L.2
Merkel, E.3
Flieder, D.4
Pathak, H.5
Koumbi, D.6
Testa, J.R.7
Eisenberg, B.8
Von, M.M.9
Godwin, A.K.10
-
23
-
-
46149111291
-
Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients
-
DOI 10.1093/annonc/mdn040
-
Braconi C, Bracci R, Bearzi I, Bianchi F, Sabato S, Mandolesi A, Belvederesi L, Cascinu S, Valeri N, Cellerino R: Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients. Ann Oncol 2008;19:1293-1298 (Pubitemid 351911960)
-
(2008)
Annals of Oncology
, vol.19
, Issue.7
, pp. 1293-1298
-
-
Braconi, C.1
Bracci, R.2
Bearzi, I.3
Bianchi, F.4
Sabato, S.5
Mandolesi, A.6
Belvederesi, L.7
Cascinu, S.8
Valeri, N.9
Cellerino, R.10
-
24
-
-
33749461709
-
Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor
-
DOI 10.1158/0008-5472.CAN-06-0165
-
Bauer S, Yu LK, Demetri GD, Fletcher JA: Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor. Cancer Res 2006;66:9153-9161 (Pubitemid 44521135)
-
(2006)
Cancer Research
, vol.66
, Issue.18
, pp. 9153-9161
-
-
Bauer, S.1
Yu, L.K.2
Demetri, G.D.3
Fletcher, J.A.4
-
25
-
-
34248512697
-
Beyond imatinib: Second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors
-
von Mehren M: Beyond imatinib: Second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors. Clin Colorectal Cancer (Suppl 1) 2006;6:S30-S34
-
(2006)
Clin Colorectal Cancer
, vol.6
, Issue.SUPPL. 1
-
-
Von Mehren, M.1
-
26
-
-
0033793213
-
Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT)
-
Miettinen M, Sobin LH, Sarlomo-Rikala M: Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT). Mod Pathol 2000;13:1134-1142
-
(2000)
Mod Pathol
, vol.13
, pp. 1134-1142
-
-
Miettinen, M.1
Sobin, L.H.2
Sarlomo-Rikala, M.3
-
27
-
-
0035142836
-
Gastrointestinal stromal tumors - Definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis
-
DOI 10.1007/s004280000338
-
Miettinen M, Lasota J: Gastrointestinal stromal tumors: Definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch 2001;438:1-12 (Pubitemid 32128184)
-
(2001)
Virchows Archiv
, vol.438
, Issue.1
, pp. 1-12
-
-
Miettinen, M.1
Lasota, J.2
-
28
-
-
2142747025
-
KIT-negative gastrointestinal stromal tumors: Proof of concept and therapeutic implications
-
DOI 10.1097/00000478-200407000-00007
-
Medeiros F, Corless CL, Duensing A, Hornick JL, Oliveira AM, Heinrich MC, Fletcher JA, Fletcher CD: KIT-negative gastrointestinal stromal tumors proof of concept and therapeutic implications. Am J Surg Pathol 2004;28:889-894 (Pubitemid 38856844)
-
(2004)
American Journal of Surgical Pathology
, vol.28
, Issue.7
, pp. 889-894
-
-
Medeiros, F.1
Corless, C.L.2
Duensing, A.3
Hornick, J.L.4
Oliveira, A.M.5
Heinrich, M.C.6
Fletcher, J.A.7
Fletcher, C.D.M.8
-
29
-
-
22144464484
-
Changing phenotype of gastrointestinal stromal tumours under imatinib mesylate treatment: A potential diagnostic pitfall
-
DOI 10.1111/j.1365-2559.2005.02179.x
-
Pauwels P, Debiec-Rychter M, Stul M, De Wever I, Van Oosterom AT, Sciot R: Changing phenotype of gastrointestinal stromal tumours under imatinib mesylate treatment: A potential diagnostic pitfall. Histopathology 2005;58:41-47 (Pubitemid 40978812)
-
(2005)
Histopathology
, vol.47
, Issue.1
, pp. 41-47
-
-
Pauwels, P.1
Debiec-Rychter, M.2
Stul, M.3
De, W.I.4
Van, O.A.T.5
Sciot, R.6
-
30
-
-
0033782218
-
Congenital gastrointestinal stromal tumors is indistinguishable from the adult form, but does not express CD117 and carries a favourable prognosis
-
Bates AW, Feakins RM, Scheimberg I: Congenital gastrointestinal stromal tumors is indistinguishable from the adult form, but does not express CD117 and carries a favourable prognosis. Histopathology 2000;37:316-322
-
(2000)
Histopathology
, vol.37
, pp. 316-322
-
-
Bates, A.W.1
Feakins, R.M.2
Scheimberg, I.3
-
31
-
-
49649119001
-
Molecular characterization of pediatric gastrointestinal stromal tumors
-
Agaram NP, Laquaglia MP, Ustun B, Guo T, Wong GC, Socci ND, Maki RG, DeMatteo RP, Besmer P, Antonescu CR: Molecular characterization of pediatric gastrointestinal stromal tumors. Clin Cancer Res 2008;14:3204-3215
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3204-3215
-
-
Agaram, N.P.1
Laquaglia, M.P.2
Ustun, B.3
Guo, T.4
Wong, G.C.5
Socci, N.D.6
Maki, R.G.7
DeMatteo, R.P.8
Besmer, P.9
Antonescu, C.R.10
-
32
-
-
1842426806
-
Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity
-
DOI 10.1002/path.1546
-
Debiec-Rychter M, Wasag B, Stul M, De Wever I, Van Oosterom A, Hagemeijer A, Sciot R: Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity. J Pathol 2004;202:430-438 (Pubitemid 38456161)
-
(2004)
Journal of Pathology
, vol.202
, Issue.4
, pp. 430-438
-
-
Debiec-Rychter, M.1
Wasag, B.2
Stul, M.3
De, W.I.4
Van, O.A.5
Hagemeijer, A.6
Sciot, R.7
-
33
-
-
16444380600
-
PKC theta, a novel immunohistochemical marker for gastrointestinal stromal tumors (GIST), especially useful for identifying KIT-negative tumors
-
DOI 10.1111/j.1440-1827.2005.01806.x
-
Motegi A, Sakurai S, Nakayama H, Sano T, Oyama T, Nakajima T: PKC theta, a novel immunohistochemical marker for gastrointestinal stromal tumors (GIST), especially useful for identifying KIT negative tumors. Pathol Int 2005;55:106-112 (Pubitemid 40477221)
-
(2005)
Pathology International
, vol.55
, Issue.3
, pp. 106-112
-
-
Motegi, A.1
Sakurai, S.2
Nakayama, H.3
Sano, T.4
Oyama, T.5
Nakajima, T.6
-
34
-
-
0035893766
-
Gastrointestinal stromal tumors with KIT mutations exhibit a remarkably homogeneous gene expression profile
-
Allander SV, Nupponen NN, Ringnér M, Hostetter G, Maher GW, Goldberger N, Chen Y, Carpten J, Elkahloun AG, Meltzer PS: Gastrointestinal stromal tumors with KIT mutation exhibits a remarkably homogenous gene expression profile. Cancer Res 2001;61:8624-8628 (Pubitemid 34013866)
-
(2001)
Cancer Research
, vol.61
, Issue.24
, pp. 8624-8628
-
-
Allander, S.V.1
Nupponen, N.N.2
Ringner, M.3
Hostetter, G.4
Maher, G.W.5
Goldberger, N.6
Chen, Y.7
Carpten, J.8
Elkahloun, A.G.9
Meltzer, P.S.10
-
35
-
-
0037070754
-
Molecular characterisation of soft tissue tumours: A gene expression study
-
DOI 10.1016/S0140-6736(02)08270-3
-
Nielsen TO, West RB, Linn SC, Alter O, Knowling MA, O'Connell JX, Zhu S, Fero M, Sherlock G, Pollack JR, Brown PO, Botstein D, van de Rijn M: Molecular characterization of soft tissue tumours: A gene expression study. Lancet 2002;359:1301-1307 (Pubitemid 34310636)
-
(2002)
Lancet
, vol.359
, Issue.9314
, pp. 1301-1307
-
-
Nielsen, T.O.1
West, R.B.2
Linn, S.C.3
Alter, O.4
Knowling, M.A.5
O'Connell, J.X.6
Zhu, S.7
Fero, M.8
Sherlock, G.9
Pollack, J.R.10
Brown, P.O.11
Botstein, D.12
De Van, R.M.13
-
36
-
-
0027418818
-
Molecular cloning and characterization of PKCtheta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells
-
Baier G, Telford D, Giampa L, Coggeshall KM, Baier-Bitterlich G, Isakov N, Altman A: Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells. J Biol Chem 1993;268:4997-5004 (Pubitemid 23081623)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.7
, pp. 4997-5004
-
-
Baier, G.1
Telford, D.2
Giampa, L.3
Coggeshall, K.M.4
Baier-Bitterlich, G.5
Isakov, N.6
Altman, A.7
-
37
-
-
0027153592
-
Molecular cloning and expression of a cDNA encoding a novel isoenzyme of protein kinase C (nPKC). A new member of the nPKC family expressed in skeletal muscle, megakaryoblastic cells, and platelets
-
Chang JD, Xu Y, Raychowdhury MK, Ware JA: Molecular cloning and expression of a cDNA encoding a novel isoenzyme of protein kinase C (nPKC): A new member of the nPKC family expressed in skeletal muscle, megakaryoblastic cells, and platelets. J Biol Chem 1993;268:14208-14214 (Pubitemid 23195543)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.19
, pp. 14208-14214
-
-
Chang, J.D.1
Xu, Y.2
Raychowdhury, M.K.3
Ware, J.A.4
-
38
-
-
0034996065
-
Protein kinase C isoenzyme: Selective expression pattern of protein kinase C-θ during mouse development
-
DOI 10.1016/S0925-4773(01)00357-4, PII S0925477301003574
-
Wilda M, Ghaffari-Tabrizi N, Reisert I, Utermann G, Baier G, Hameister H: Protein kinase C isoenzyme: Selective expression pattern of protein kinase C-θ during mouse development. Mech Dev 2001;103:197-200 (Pubitemid 32463269)
-
(2001)
Mechanisms of Development
, vol.103
, Issue.1-2
, pp. 197-200
-
-
Wilda, M.1
Ghaffari-Tabrizi, N.2
Reisert, I.3
Utermann, G.4
Baier, G.5
Hameister, H.6
-
39
-
-
0037732988
-
Localization of protein kinase C immunoreactivity to interstitial cells of Cajal in guinea-pig gastrointestinal tract
-
Southwell BR: Localization of protein kinase C immunoreactivity to interstitial cells of Cajal in guinea-pig gastrointestinal tract. Neurogastroenterol Motil 2003;15:139-147
-
(2003)
Neurogastroenterol Motil
, vol.15
, pp. 139-147
-
-
Southwell, B.R.1
-
40
-
-
3042538269
-
Protein kinase C c is highly expressed in gastrointestinal stromal tumors but not in other mesenchymal neoplasias
-
DOI 10.1158/1078-0432.CCR-04-0630
-
Blay P, Astudillo A, Buesa JM, Campo E, Abad M, García- García J, Miquel R, Marco V, Sierra M, Losa R, Lacave A, Braña A, Balbín M, Freije JM: Protein kinase c is highly expressed in gastrointestinal stromal tumors but not in other mesenchymal neoplasias. Clin Cancer Res 2004;10:4089-4095 (Pubitemid 38812487)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.12 I
, pp. 4089-4095
-
-
Blay, P.1
Astudillo, A.2
Buesa, J.M.3
Campo, E.4
Abad, M.5
Garcia-Garcia, J.6
Miquel, R.7
Marco, V.8
Sierra, M.9
Losa, R.10
Lacave, A.11
Brana, A.12
Balbin, M.13
Freije, J.M.P.14
-
41
-
-
62849083680
-
Monoclonal antibody DOG1.1 shows higher sensitivity than kit in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes
-
Liegl B, Hornick JL, Corless CL, Fletcher CD: Monoclonal antibody DOG1.1 shows higher sensitivity than kit in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes. Am J Surg Pathol 2009;33:437-446
-
(2009)
Am J Surg Pathol
, vol.33
, pp. 437-446
-
-
Liegl, B.1
Hornick, J.L.2
Corless, C.L.3
Fletcher, C.D.4
-
42
-
-
52149094786
-
Protein kinase C-theta regulates KIT expression and proliferation in gastrointestinal stromal tumors
-
Ou WB, Zhu MJ, Demetri GD, Fletcher CD, Fletcher JA: Protein kinase C-theta regulates KIT expression and proliferation in gastrointestinal stromal tumors. Oncogene 2008;27:5624-5634
-
(2008)
Oncogene
, vol.27
, pp. 5624-5634
-
-
Ou, W.B.1
Zhu, M.J.2
Demetri, G.D.3
Fletcher, C.D.4
Fletcher, J.A.5
-
43
-
-
3042594995
-
The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status
-
West RB, Corless CL, Chen X, Rubin BP, Subramanian S, Montgomery K, Zhu S, Ball CA, Nielsen TO, Patel R, Goldblum JR, Brown PO, Heinrich MC, van de Rijn M: The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status. Am J Pathol 2004;165:107-113 (Pubitemid 38821818)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.1
, pp. 107-113
-
-
West, R.B.1
Corless, C.L.2
Chen, X.3
Rubin, B.P.4
Subramanian, S.5
Montgomery, K.6
Zhu, S.7
Ball, C.A.8
Nielsen, T.O.9
Patel, R.10
Goldblum, J.R.11
Brown, P.O.12
Heinrich, M.C.13
De Van, R.M.14
-
44
-
-
0042628162
-
FLJ10261 gene, located within the CCND1-EMS1 locus on the human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products
-
Katoh M, Katoh M: FLJ10261 gene, located within the CCND1-EMS1 locus on the human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products. Int J Oncol 2003;22:1375-1381
-
(2003)
Int J Oncol
, vol.22
, pp. 1375-1381
-
-
Katoh, M.1
Katoh, M.2
-
45
-
-
48449101034
-
Mutation analysis of the novel gene DOG1 in gastrointestinal stromal tumors (GIST)
-
Miwa S, Nakajima T, Murai Y, Takano Y, Sugiyama T: Mutation analysis of the novel gene DOG1 in gastrointestinal stromal tumors (GIST). J Gastroenterol 2008;43:531-537
-
(2008)
J Gastroenterol
, vol.43
, pp. 531-537
-
-
Miwa, S.1
Nakajima, T.2
Murai, Y.3
Takano, Y.4
Sugiyama, T.5
-
46
-
-
54949112835
-
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity
-
Caputo A, Caci E, Ferrera L, Pedemonte N, Barsanti C, Sondo E, Pfeffer U, Ravazzolo R, Zegarra-Moran O, Galietta LJ: TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science 2008;322:590-594
-
(2008)
Science
, vol.322
, pp. 590-594
-
-
Caputo, A.1
Caci, E.2
Ferrera, L.3
Pedemonte, N.4
Barsanti, C.5
Sondo, E.6
Pfeffer, U.7
Ravazzolo, R.8
Zegarra-Moran, O.9
Galietta, L.J.10
-
47
-
-
55249091085
-
TMEM16A confers receptor-activated calcium-dependent chloride conductance
-
Yang YD, Cho H, Koo JY, Tak MH, Cho Y, Shim WS, Park SP, Lee J, Lee B, Kim BM, Raouf R, Shin YK, Oh UYD, Cho H, Koo JY: TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature 2008;455:1210-1215
-
(2008)
Nature
, vol.455
, pp. 1210-1215
-
-
Yang, Y.D.1
Cho, H.2
Koo, J.Y.3
Tak, M.H.4
Cho, Y.5
Shim, W.S.6
Park, S.P.7
Lee, J.8
Lee, B.9
Kim, B.M.10
Raouf, R.11
Shin, Y.K.12
Oh, U.Y.D.13
Cho, H.14
Koo, J.Y.15
-
48
-
-
38649098794
-
A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors
-
DOI 10.1097/PAS.0b013e3181238cec, PII 0000047820080200000005
-
Espinosa I, Lee CH, Kim MK, Rouse BT, Subramanian S, Montgomery K, Varma S, Corless CL, Heinrich MC, Smith KS, Wang Z, Rubin B, Nielsen TO, Seitz RS, Ross DT, West RB, Cleary ML, van de Rijn M: A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors. Am J Surg Pathol 2008;32:210-218 (Pubitemid 351172135)
-
(2008)
American Journal of Surgical Pathology
, vol.32
, Issue.2
, pp. 210-218
-
-
Espinosa, I.1
Lee, C.-H.2
Kim, M.K.3
Rouse, B.-T.4
Subramanian, S.5
Montgomery, K.6
Varma, S.7
Corless, C.L.8
Heinrich, M.C.9
Smith, K.S.10
Wang, Z.11
Rubin, B.12
Nielsen, T.O.13
Seitz, R.S.14
Ross, D.T.15
West, R.B.16
Cleary, M.L.17
De Van, R.M.18
-
49
-
-
72449212435
-
Insulin-like growth factor 1 receptor expression in wild-type GISTs: A potential novel therapeutic target
-
Pantaleo MA, Astolfi A, Di Battista M, Heinrich MC, Paterini P, Scotlandi K, Santini D, Catena F, Manara MC, Nannini M, Maleddu A, Saponara M, Lolli C, Formica S, Biasco G: Insulin-like growth factor 1 receptor expression in wild-type GISTs: A potential novel therapeutic target. Int J Cancer 2009;125:2991-2994
-
(2009)
Int J Cancer
, vol.125
, pp. 2991-2994
-
-
Pantaleo, M.A.1
Astolfi, A.2
Di Battista, M.3
Heinrich, M.C.4
Paterini, P.5
Scotlandi, K.6
Santini, D.7
Catena, F.8
Manara, M.C.9
Nannini, M.10
Maleddu, A.11
Saponara, M.12
Lolli, C.13
Formica, S.14
Biasco, G.15
-
50
-
-
0028908814
-
Gastrointestinal stromal tumors: Value of CD34 antigen in their identification and separation from true leiomyomas and schwannomas
-
Miettinen M, Virolainen M, Sarlomo-Rikala M: Gastrointestinal stromal tumors: Value of CD34 antigen in their identification and separation from true leiomyomas and schwannomas. Am J Surg Pathol 1995;19:207-216
-
(1995)
Am J Surg Pathol
, vol.19
, pp. 207-216
-
-
Miettinen, M.1
Virolainen, M.2
Sarlomo-Rikala, M.3
-
51
-
-
11144284051
-
Gastrointestinal stromal tumors of the stomach: A clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up
-
DOI 10.1097/01.pas.0000146010.92933.de
-
Miettinen M, Sobin LH, Lasota J: Gastrointestinal stromal tumors of the stomach: A clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up. Am J Surg Pathol 2005;29:52-68 (Pubitemid 40023952)
-
(2005)
American Journal of Surgical Pathology
, vol.29
, Issue.1
, pp. 52-68
-
-
Miettinen, M.1
Sobin, L.H.2
Lasota, J.3
-
52
-
-
33646685694
-
Gastrointestinal stromal tumors of the jejunum and ileum: A clinicopathologic, immunohistochemical, and molecular genetic study of 906 cases before imatinib with long-term follow-up
-
DOI 10.1097/00000478-200604000-00008, PII 0000047820060400000008
-
Miettinen M, Makhlouf H, Sobin LH, Lasota J: Gastrointestinal stromal tumors of the jejunum and ileum: A clinicopathologic, immunohistochemical, and molecular genetic study of 906 cases before imatinib with long-term follow-up. Am J Surg Pathol 2006;30:477-489 (Pubitemid 43740149)
-
(2006)
American Journal of Surgical Pathology
, vol.30
, Issue.4
, pp. 477-489
-
-
Miettinen, M.1
Makhlouf, H.2
Sobin, L.H.3
Lasota, J.4
-
53
-
-
0033793213
-
Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT)
-
Miettinen M, Sobin LH, Sarlomo-Rikala M: Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT). Mod Pathol 2000;13:1134-1142
-
(2000)
Mod Pathol
, vol.13
, pp. 1134-1142
-
-
Miettinen, M.1
Sobin, L.H.2
Sarlomo-Rikala, M.3
-
54
-
-
0033793213
-
Immunohistochemical spectrum of GISTs of different locations and their differential diagnosis
-
Miettinen M, Sobin LH, Sarlomo-Rikala M: Immunohistochemical spectrum of GISTs of different locations and their differential diagnosis. Mod Pathol 2000;13:1134-1142
-
(2000)
Mod Pathol
, vol.13
, pp. 1134-1142
-
-
Miettinen, M.1
Sobin, L.H.2
Sarlomo-Rikala, M.3
-
55
-
-
0033974638
-
Esophageal stromal tumors: A clinicopathologic, immunohistochemical, and molecular genetic study of 17 cases and comparison with esophageal leiomyomas and leiomyosarcomas
-
DOI 10.1097/00000478-200002000-00007
-
Miettinen M, Sarlomo-Rikala M, Sobin LH, Lasota J: Esophageal stromal tumors: A clinicopathologic, immunohistochemical, and molecular genetic study of 17 cases and comparison with esophageal leiomyomas and leiomyosarcomas. Am J Surg Pathol 2000;24:211-222 (Pubitemid 30078710)
-
(2000)
American Journal of Surgical Pathology
, vol.24
, Issue.2
, pp. 211-222
-
-
Miettinen, M.1
Sarlomo-Rikala, M.2
Sobin, L.H.3
Lasota, J.4
-
56
-
-
22144464484
-
Changing phenotype of gastrointestinal stromal tumours under imatinib mesylate treatment: A potential diagnostic pitfall
-
DOI 10.1111/j.1365-2559.2005.02179.x
-
Pauwels P, Debiec-Rychter M, Stul M, DeWever I, van Oosterom AT, Sciot R: Changing phenotype of gastrointestinal stromal tumours under imatinib mesylate treatment: A potential diagnostic pitfall. Histopathology 2005;47:41-47 (Pubitemid 40978812)
-
(2005)
Histopathology
, vol.47
, Issue.1
, pp. 41-47
-
-
Pauwels, P.1
Debiec-Rychter, M.2
Stul, M.3
De, W.I.4
Van, O.A.T.5
Sciot, R.6
|