Differential toxicity profile of ricin isoforms correlates with their glycosylation levels

Toxicology

Volumn 282, Issue 1-2, 2011, Pages 56-67

  Sehgal, Payal ^a   Kumar, Om ^a   Kameswararao, Mula ^a   Ravindran, Jayaraj ^a   Khan, Mohsin ^a   Sharma, Shashi ^a   Vijayaraghavan, Rajagopalan ^a   Prasad, G B K S ^b  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

^b JIWAJI UNIVERSITY   (India)

Author keywords

Cytotoxicity; Glycosylation; Isoforms; MALDI TOF MS; Oxidative stress; Ricin

Indexed keywords

CATALASE; GLYCOPEPTIDE; HEXOSE; ISOPROTEIN; LACTATE DEHYDROGENASE; MANNOSE; REACTIVE OXYGEN METABOLITE; RICIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA FRAGMENTATION; ENZYME ACTIVITY; ENZYME ASSAY; GLYCOSYLATION; IN VITRO STUDY; ION EXCHANGE CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; VERO CELL;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; DNA FRAGMENTATION; GLYCOPEPTIDES; GLYCOSYLATION; IMMUNOTOXINS; INHIBITORY CONCENTRATION 50; MANNOSE; MOLECULAR WEIGHT; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; PROTEIN ISOFORMS; REACTIVE OXYGEN SPECIES; RICIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY; VERO CELLS;

RICINUS COMMUNIS;

EID: 79951581494     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2011.01.012     Document Type: Article

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