Neuroimaging correlates of aggression in schizophrenia: An update

Current Opinion in Psychiatry

Volumn 24, Issue 2, 2011, Pages 100-106

  Hoptman, Matthew J ^a,b   Antonius, Daniel ^b  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

aggression; MRI; schizophrenia; violence

Indexed keywords

AGGRESSION; ARTICLE; BRAIN RADIOGRAPHY; BRAIN REGION; BRAIN SIZE; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENETIC HETEROGENEITY; HUMAN; INFERIOR FRONTAL CORTEX; INFERIOR TEMPORAL CORTEX; NEUROANATOMY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOTON EMISSION TOMOGRAPHY; POSITRON EMISSION TOMOGRAPHY; SCHIZOPHRENIA; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TEMPORAL LOBE; TREATMENT OUTCOME;

AGGRESSION; BRAIN; BRAIN MAPPING; HUMANS; MAGNETIC RESONANCE IMAGING; POSITRON-EMISSION TOMOGRAPHY; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 79951580556     PISSN: 09517367     EISSN: None     Source Type: Journal    
DOI: 10.1097/YCO.0b013e328342c8e0     Document Type: Article

References (66)

1. Hodgins S, Alderton J, Cree A, et al. Aggressive behaviour, victimization and crime among severely mentally ill patients requiring hospitalisation. Br J Psychiatry 2007; 191:343-350. (Pubitemid 47555983)
2. Teplin LA, McClelland GM, Abram KM, Weiner DA. Crime victimization in adults with severe mental illness: comparison with the National Crime Victimization Survey. Arch Gen Psychiatry 2005; 62:911-921. (Pubitemid 41126886)
3. Swanson J, Holzer C III, Ganju V, Tsutumo Jono R. Violence and psychiatric disorder in the community: evidence from the epidemiologic catchment area survey. Hosp Commun Psychiatry 1990; 41:761-770. (Pubitemid 20244681)
4. Walsh E, Buchanan A, Fahy T. Violence and schizophrenia: examining the evidence. Br J Psychiatry 2002; 180:490-495. (Pubitemid 34596798)
5. Swanson JW, Swartz MS, Van Dorn RA, et al. A national study of violent behavior in persons with schizophrenia. Arch Gen Psychiatry 2006; 63:490-499.
6. Fazel S, Langstrom N, Hjern A, et al. Schizophrenia, substance abuse, and violent crime. JAMA 2009; 301:2016-2023.
7. Swanson JW. Mental disorder, substance abuse, and community violence: an epidemiological approach. In: Monahan J, Steadman HJ, editors. Violence and mental disorder: developments in risk assessment. Chicago, IL: University of Chicago Press; 1994. pp. 101-136.
8. Steadman HJ, Mulvey EP, Monahan J, et al. Violence by people discharged from acute psychiatric inpatient facilities and by others in the same neighborhoods. Arch Gen Psychiatry 1998; 55:393-401. (Pubitemid 28237272)
9. Volavka J. Neurobiology of violence. 2nd ed. Washington, DC: APA Publishing; 2002.
10. McEvoy JP. The costs of schizophrenia. J Clin Psychiatry 2007; 68 (Suppl 14):4-7.
11. Ferriman A. The stigma of schizophrenia. BMJ 2000; 320:522.
12. Link BG, Phelan JC, Bresnahan M, et al. Public conceptions of mental illness: labels, causes, dangerousness, and social distance. Am J Public Health 1999; 89:1328-1333. (Pubitemid 29404554)
13. Van Dorn RA, Swanson JW, Elbogen EB, Swartz MS. A comparison of stigmatizing attitudes toward persons with schizophrenia in four stakeholder groups: perceived likelihood of violence and desire for social distance. Psychiatry 2005; 68:152-163. (Pubitemid 41045518)
14. Schug RA, Raine A. Comparative meta-analyses of neuropsychological functioning in antisocial schizophrenic persons. Clin Psychol Rev 2009; 29:230-242.
15. Swanson JW, Swartz MS, Van Dorn RA, et al. Comparison of antipsychotic medication effects on reducing violence in people with schizophrenia. Br J Psychiatry 2008; 193:37-43. (Pubitemid 351946806)
16. Volavka J, Czobor P, Nolan K, et al.Overt aggression and psychotic symptoms in patients with schizophrenia treated with clozapine, olanzapine, risperidone, or haloperidol. J Clin Psychopharmacol 2004; 24:225-228. (Pubitemid 38380848)
17. Cherek DR. A manual for the Point Subtraction Aggression Paradigm. Houston, TX: University of Texas, Houston; 1992.
18. Taylor S. Aggressive behavior and physiological arousal as a function of provocation and the tendency to inhibit aggression. J Personality 1967; 35:297-310.
19. Buckley PF, Wirshing DA, Bhushan P, et al. Lack of insight in schizophrenia: impact on treatment adherence. CNS Drugs 2007; 21:129-141.
20. Swanson JW, SwartzMS, Elbogen EB. Effectiveness of atypical antipsychotic medications in reducing violent behavior among persons with schizophrenia in community-based treatment. Schizophr Bull 2004; 30:3-20. (Pubitemid 38568781)
21. Swanson JW, Van Dorn RA, Swartz MS, et al. Alternative pathways to violence in persons with schizophrenia: the role of childhood antisocial behavior problems. Law Hum Behav 2008; 32:228-240. (Pubitemid 351692047)
22. Naudts K, Hodgins S. Neurobiological correlates of violent behavior among persons with schizophrenia. Schizophr Bull 2006; 32:562-572. (Pubitemid 43992329)
23. Krakowski M, Czobor P, Chou JC. Course of violence in patients with schizophrenia: relationship to clinical symptoms. Schizophr Bull 1999; 25:505-517.
24. Hodgins S. Violent behaviour among people with schizophrenia: a framework for investigations of causes, and effective treatment, and prevention. Philos Trans R Soc Lond B Biol Sci 2008; 363:2505-2518. (Pubitemid 351915140)
25. Hodgins S, Tiihonen J, Ross D. The consequences of conduct disorder for males who develop schizophrenia: associations with criminality, aggressive behavior, substance use, and psychiatric services. Schizophr Res 2005; 78:323-335. (Pubitemid 41254033)
26. Krakowski M. Schizophrenia with aggressive and violent behaviors. Psychiatric Annals 2005; 35:45-49. (Pubitemid 40186664)
27. Siever LJ. Neurobiology of aggression and violence. Am J Psychiatry 2008; 165:429-442. (Pubitemid 351694285)
28. Dolan MC, Fullam RS. Psychopathy and functional magnetic resonance imaging blood oxygenation level-dependent responses to emotional faces in violent patients with schizophrenia. Biol Psychiatry 2009; 66:570-577.
29. Frick PJ, White SF. Research review: the importance of callous-unemotional traits for developmental models of aggressive and antisocial behavior. J Child Psychol Psychiatry 2008; 49:359-375. (Pubitemid 351432222)
30. American Psychiatric Association. Antisocial personality disorder. Washington, DC: American Psychiatric Association; 2010.
31. Sunak S. Deficient affective experience and violence in schizophrenia. London: King s College; 2006.
32. Nolan KA, Czobor P, Roy BB, et al. Characteristics of assaultive behavior in psychiatric inpatients. Psychiatric Serv 2003; 54:1012-1016. (Pubitemid 36793456)
33. Raine A, Buchsbaum MS, Stanley J, et al. Selective reductions in prefrontal glucose metabolism in murderers. Biol Psychiatry 1994; 36:365-373. (Pubitemid 24305943)
34. Raine A, Buchsbaum M, LaCasse L. Brain abnormalities in murderers indicated by positron emission tomography. Biol Psychiatry 1997; 42:495-508. (Pubitemid 27394617)
35. Raine A, Meloy JR, Bihrle S, et al. Reduced prefrontal and increased subcortical brain functioning assessed using positron emission tomography in predatory and affective murderers. Behav Sci Law 1998; 16:319-332. (Pubitemid 28451316)
36. Spalletta G, Troisi A, Alimenti S, et al. Reduced prefrontal cognitive activation associated with aggression in schizophrenia. Schizophr Res 2001; 60:134-135. (Pubitemid 32510896)
37. Wong MTH, Fenwick PBC, Lumsden J, et al. Positron emission tomography in male violent offenders with schizophrenia. Psychiatry Res Neuroimag 1997; 68:111-123. (Pubitemid 27191434)
38. Hoptman MJ, Volavka J, Czobor P, et al. Aggression and quantitative MRI measures of caudate in chronic schizophrenia and schizoaffective disorder. J Neuropsychiatry Clin Neurosci 2006; 18:509-515. (Pubitemid 44713889)
39. Hoptman MJ, Volavka J, Weiss EM, et al. Quantitative MRI measures of orbitofrontal cortex in patients with chronic schizophrenia or schizoaffective disorder. Psychiatry Res Neuroimag 2005; 140:133-145. (Pubitemid 41540425)
40. Rüsch N, Spoletini I, Wilke M, et al. Inferior frontal white matter volume and suicidality in schizophrenia. Psychiatry Res 2008; 164:206 214.
41. Narayan VM, Narr KL, Kumari V, et al. Regional cortical thinning in subjects with violent antisocial personality disorder or schizophrenia. Am J Psychiatry 2007; 164:1418-1427. (Pubitemid 47461143)
42. Hoptman MJ, Volavka J, Johnson G, et al. Frontal white matter, aggression and impulsivity in men with schizophrenia. Biol Psychiatry 2002; 52: 9-14. (Pubitemid 34655551)
43. Joyal CC, Putkonen A, Mancini-Marie A, et al. Violent persons with schizophrenia and comorbid disorders: a functional magnetic resonance imaging study. Schizophr Res 2007; 91:97-102.
44. Kumari V, Das M, Taylor PJ, et al. Neural and behavioural responses to threat in men with a history of serious violence and schizophrenia or antisocial personality disorder. Schizophr Res 2009; 110:47-58.
45. Hoptman MJ, D'Angelo D, Catalano D, et al. Amygdalofrontal functional connectivity and aggression in schizophrenia. Schizophrenia Bull 2010; 36:1020-1028.
46. Yang Y, Raine A. Prefrontal structural and functional brain imaging findings in antisocial, violent, and psychopathic individuals: a meta-analysis. Psychiatry Res 2009; 174:81-88.
47. Raine A, Lencz T, Bihrle S, et al. Reduced prefrontal gray matter volume and reduced autonomic activity in antisocial personality disorder. Arch Gen Psychiatry 2000; 57:119-127. (Pubitemid 30075261)
48. Keshavan MS, Bagwell WW, Haas GL, et al. Changes in caudate volume with neuroleptic treatment. Lancet 1994; 344:1434. (Pubitemid 24365327)
49. Chakos MH, Lieberman JA, Bilder RM, et al. Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs. Am J Psychiatry 1994; 151:1430-1436. (Pubitemid 24301686)
50. Lee H, Tarazi FI, Chakos M, et al. Effects of chronic treatment with typical and atypical antipsychotic drugs on the rat striatum. Life Sci 1999; 64:1595-1602. (Pubitemid 29185340)
51. Glenn AL, Raine A, Yaralian PS, Yang Y. Increased volume of the striatum in psychopathic individuals. Biol Psychiatry 2010; 67:52-58.
52. De Brito SA, Mechelli A, Wilke M, et al. Size matters: increased grey matter in boys with conduct problems and callous-unemotional traits. Brain 2009; 132:843-852.
53. Tiihonen J, Rossi R, Laakso MP, et al. Brain anatomy of persistent violent offenders: more rather than less. Psychiatry Res 2008; 163:201-212.
54. Coccaro EF, Berman ME, Kavoussi RJ. Assessment of life history of aggression: development and psychometric characteristics. Psychiatry Res 1997; 73:147-157. (Pubitemid 28088171)
55. Buss A, Durkee A. An inventory for assessing different kinds of hostility. J Consulting Psychol 1957; 21:343-349.
56. Ardekani BA, Bappal A, D'Angelo D, et al. Brain morphometry using diffusionweighted magnetic resonance imaging: application to schizophrenia. NeuroReport 2005; 16:1455-1459. (Pubitemid 41805663)
57. Narr KL, Hageman N, Woods RP, et al. Mean diffusivity: a biomarker for CSFrelated disease and genetic liability effects in schizophrenia. Psychiatry Res 2009; 171:20-32.
58. Kiehl KA, Smith AM, Hare RD, et al. Limbic abnormalities in affective processing by criminal psychopaths as revealed by functional magnetic resonance imaging. Biol Psychiatry 2001; 50:677-684. (Pubitemid 33043770)
59. Raine A, Park S, Lencz T, et al. Reduced right hemisphere activation in severely abused violent offenders during a working memory task: an fMRI study. Aggressive Behav 2001; 27:111-129.
60. Veit R, Flor H, Erb M, et al. Brain circuits involved in emotional learning in antisocial behavior and social phobia in humans. Neurosci Lett 2002; 328:233-236. (Pubitemid 34876654)
61. Jones AP, Laurens KR, Herba CM, et al. Amygdala hypoactivity to fearful faces in boys with conduct problems and callous-unemotional traits. Am J Psychiatry 2009; 166:95-102.
62. Marsh AA, Finger EC, Mitchell DG, et al. Reduced amygdala response to fearful expressions in children and adolescents with callous-unemotional traits and disruptive behavior disorders. Am J Psychiatry 2008; 165:712-720. (Pubitemid 351810540)
63. Friston KJ. Functional and effective connectivity in neuroimaging: a synthesis. Human Brain Mapping 1994; 2:56-78. (Pubitemid 124000442)
64. Biswal B, Yetkin FZ, Haughton VM, Hyde JS. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 1995; 34:537-541.
65. Stein JL, Wiedholz LM, Bassett DS, et al. A validated network of effective amygdala connectivity. Neuroimage 2007; 36:736-745. (Pubitemid 46915503)
66. Schmamann JD, Pandya DN. Fiber pathways of the brain. New York: Oxford University Press; 2006.