(Arene)Cl2Ru(II) complexes with N-coordinated estrogen and androgen isonicotinates: Interaction with sex hormone binding globulin and anticancer activity

Steroids

Volumn 76, Issue 4, 2011, Pages 393-399

  Schobert, Rainer ^a   Seibt, Sebastian ^a   Effenberger Neidnicht, Katharina ^a   Underhill, Caroline ^b   Biersack, Bernhard ^a   Hammond, Geoffrey L ^b  

^a UNIVERSITY OF BAYREUTH   (Germany)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Anticancer drugs; DNA binding; Ruthenium complexes; Sex hormone binding globulin; Steroid hormones

Indexed keywords

(ETA 6 BENZENE)DICHLORIDO(ISONICOTINIC ACID 17 OXOESTRA 1,3,5(10) TRIEN 3 YL ESTER)RUTHENIUM; ANDROGEN; ANDROGEN ISONICOTINATE; DICHLORIDO(ETA 6 4 CYMENE)(ISONICOTINIC ACID 17 OXOESTRA 1,3,5(10) TRIEN 3 YL ESTER)RUTHENIUM; DNA; ESTROGEN DERIVATIVE; ESTROGEN ISONICOTINATE; ESTROGEN RECEPTOR ALPHA; ISONICOTINIC ACID; PARA CYMENE; PLASMID DNA; RUTHENIUM COMPLEX; SEX HORMONE BINDING GLOBULIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; COORDINATION COMPOUND; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR; RUTHENIUM; TESTOSTERONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL; CANCER CELL CULTURE; CYTOTOXICITY; DRUG SYNTHESIS; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; IC 50; MELANOMA CELL; METALLATION; SALMON; BINDING COMPETITION; CELL MOTION; CELL PROLIFERATION; CELL STRAIN HL 60; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; METABOLISM; PROTEIN BINDING; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COORDINATION COMPLEXES; DRUG SCREENING ASSAYS, ANTITUMOR; ESTRADIOL CONGENERS; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; ISONICOTINIC ACIDS; MOLECULAR STRUCTURE; PROTEIN BINDING; RECEPTORS, ESTROGEN; RUTHENIUM; SEX HORMONE-BINDING GLOBULIN; TESTOSTERONE CONGENERS;

EID: 79951513625     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2010.12.009     Document Type: Article

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