Association Between Mannose-Binding Lectin Gene Polymorphisms and Pre-eclampsia in Brazilian Women

American Journal of Reproductive Immunology

Volumn 64, Issue 5, 2010, Pages 359-374

  Vianna, Priscila ^a   Da Silva, Gabriela Kniphoff ^a   Dos Santos, Bruno Paiva ^a   Bauer, Moisés Evandro ^b   Dalmáz, Caroline Abrão ^a   Bandinelli, Eliane ^a   Chies, José Artur Bogo ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Inflammation; MBL polymorphisms; Pre eclampsia

Indexed keywords

DNA; MANNOSE BINDING LECTIN;

ADULT; ARTICLE; BRAZIL; CHEMISTRY; CHI SQUARE DISTRIBUTION; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; GENETICS; HAPLOTYPE; HUMAN; IMMUNOLOGY; POLYMERASE CHAIN REACTION; PREECLAMPSIA; PREGNANCY; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; SITE DIRECTED MUTAGENESIS;

ADULT; BRAZIL; CHI-SQUARE DISTRIBUTION; DNA; FEMALE; GENETIC VARIATION; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MANNOSE-BINDING LECTIN; MUTAGENESIS, SITE-DIRECTED; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PRE-ECLAMPSIA; PREGNANCY; PROMOTER REGIONS, GENETIC;

EID: 79951512013     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/j.1600-0897.2010.00846.x     Document Type: Article

References (45)

1. Redman CW, Sacks GP, Sargent IL: Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 1999; 180:499-506.
2. Marzi M, Vigano A, Trabattoni D, Villa ML, Salvaggio A, Clerici E, Clerici M: Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy. Clin Exp Immunol 1996; 106:127-133.
3. Raghupathy R: Th1-type immunity is incompatible with successful pregnancy. Immunol Today 1997; 18:478-482.
4. Reinhard G, Noll A, Schlebusch H, Mallmann P, Ruecker AV: Shifts in the TH1/TH2 balance during human pregnancy correlate with apoptotic changes. Biochem Biophys Res Commun 1998; 245:933-938.
5. De Man YA, Dolhain RJ, Van De Geijn FE, Willemsen SP, Hazes JM: Disease activity of rheumatoid arthritis during pregnancy: results from a nationwide prospective study. Arthritis Rheum 2008; 59:1241-1248.
6. Lin D, Moss K, Beck JD, Hefti A, Offenbacher S: Persistently high levels of periodontal pathogens associated with preterm pregnancy outcome. J Periodontol 2007; 78:833-841.
7. Duckitt K, Harrington D: Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. BMJ 2005; 330:565.
8. Fekete A, Ver A, Bogi K, Treszl A, Rigo J Jr: Is preeclampsia associated with higher frequency of HSP70 gene polymorphisms? Eur J Obstet Gynecol Reprod Biol 2006; 126:197-200.
9. Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, Kim YM, Bdolah Y, Lim KH, Yuan HT, Libermann TA, Stillman IE, Roberts D, D'Amore PA, Epstein FH, Sellke FW, Romero R, Sukhatme VP, Letarte M, Karumanchi SA: Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med 2006; 12:642-649.
10. Redman CW, Sargent IL: Latest advances in understanding preeclampsia. Science 2005; 308:1592-1594.
11. Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 2000;183:S1-S22.
12. Gu Y, Lewis DF, Deere K, Groome LJ, Wang Y: Elevated maternal IL-16 levels, enhanced IL-16 expressions in endothelium and leukocytes, and increased IL-16 production by placental trophoblasts in women with preeclampsia. J Immunol 2008; 181:4418-4422.
13. Rusterholz C, Hahn S, Holzgreve W: Role of placentally produced inflammatory and regulatory cytokines in pregnancy and the etiology of preeclampsia. Semin Immunopathol 2007; 29:151-162.
14. Sibai B, Dekker G, Kupferminc M: Pre-eclampsia. Lancet 2005; 365:785-799.
15. Hiby SE, Walker JJ, O'Shaughnessy K M, Redman CW, Carrington M, Trowsdale J, Moffett A: Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. J Exp Med 2004; 200:957-965.
16. Vianna P, Dalmaz CA, Veit TD, Tedoldi C, Roisenberg I, Chies JA: Immunogenetics of pregnancy: role of a 14-bp deletion in the maternal HLA-G gene in primiparous pre-eclamptic Brazilian women. Hum Immunol 2007; 68:668-674.
17. Turner MW: The role of mannose-binding lectin in health and disease. Mol Immunol 2003; 40:423-429.
18. Faulk WP, Jarret R, Keane M, Johnson PM, Boackle RJ: Immunological studies of human placentae: complement components in immature and mature chorionic villi. Clin Exp Immunol 1980; 40:299-305.
19. Tedesco F, Radillo O, Candussi G, Nazzaro A, Mollnes TE, Pecorari D: Immunohistochemical detection of terminal complement complex and S protein in normal and pre-eclamptic placentae. Clin Exp Immunol 1990; 80:236-240.
20. Sziller I, Babula O, Hupuczi P, Nagy B, Rigo B, Szabo G, Papp Z, Linhares IM, Witkin SS: Mannose-binding lectin (MBL) codon 54 gene polymorphism protects against development of pre-eclampsia, HELLP syndrome and pre-eclampsia-associated intrauterine growth restriction. Mol Hum Reprod 2007; 13:281-285.
21. Van De Geijn FE, Dolhain RJ, Van Rijs W, Willemsen SP, Hazes JM, De Groot CJ: Mannose-binding lectin genotypes are associated with shorter gestational age. An evolutionary advantage of low MBL production genotypes?. Mol Immunol 2008; 45:1514-1518.
22. Van De Geijn FE, Roos A, De Man YA, Laman JD, De Groot CJ, Daha MR, Hazes JM, Dolhain RJ: Mannose-binding lectin levels during pregnancy: a longitudinal study. Hum Reprod 2007; 22:362-371.
23. Sinha D, Wells M, Faulk WP: Immunological studies of human placentae: complement components in pre-eclamptic chorionic villi. Clin Exp Immunol 1984; 56:175-184.
24. Madsen HO, Garred P, Thiel S, Kurtzhals JA, Lamm LU, Ryder LP, Svejgaard A: Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol 1995; 155:3013-3020.
25. Garred P, Madsen HO, Halberg P, Petersen J, Kronborg G, Svejgaard A, Andersen V, Jacobsen S: Mannose-binding lectin polymorphisms and susceptibility to infection in systemic lupus erythematosus. Arthritis Rheum 1999; 42:2145-2152.
26. Kilpatrick DC: Mannan-binding lectin and its role in innate immunity. Transfus Med 2002; 12:335-352.
27. Madsen HO, Videm V, Svejgaard A, Svennevig JL, Garred P: Association of mannose-binding-lectin deficiency with severe atherosclerosis. Lancet 1998; 352:959-960.
28. Tsutsumi A, Ikegami H, Takahashi R, Murata H, Goto D, Matsumoto I, Fujisawa T, Sumida T: Mannose binding lectin gene polymorphism in patients with type I diabetes. Hum Immunol 2003; 64:621-624.
29. Monticielo OA, Mucenic T, Xavier RM, Brenol JC, Chies JA: The role of mannose-binding lectin in systemic lupus erythematosus. Clin Rheumatol 2008; 27:413-419.
30. Roos A, Bouwman LH, Munoz J, Zuiverloon T, Faber-Krol MC, Fallaux-van Den Houten FC, Klar-Mohamad N, Hack CE, Tilanus MG, Daha MR: Functional characterization of the lectin pathway of complement in human serum. Mol Immunol 2003; 39:655-668.
31. Larsen F, Madsen HO, Sim RB, Koch C, Garred P: Disease-associated mutations in human mannose-binding lectin compromise oligomerization and activity of the final protein. J Biol Chem 2004; 279:21302-21311.
32. Terai I, Kobayashi K, Matsushita M, Miyakawa H, Mafune N, Kikuta H: Relationship between gene polymorphisms of mannose-binding lectin (MBL) and two molecular forms of MBL. Eur J Immunol 2003; 33:2755-2763.
33. Annells MF, Hart PH, Mullighan CG, Heatley SL, Robinson JS, Bardy P, McDonald HM: Interleukins-1, -4, -6, -10, tumor necrosis factor, transforming growth factor-beta, FAS, and mannose-binding protein C gene polymorphisms in Australian women: risk of preterm birth. Am J Obstet Gynecol 2004; 191:2056-2067.
34. Annells MF, Hart PH, Mullighan CG, Heatley SL, Robinson JS, McDonald HM: Polymorphisms in immunoregulatory genes and the risk of histologic chorioamnionitis in Caucasoid women: a case control study. BMC Pregnancy Childbirth 2005; 5:4.
35. Christiansen OB, Kilpatrick DC, Souter V, Varming K, Thiel S, Jensenius JC: Mannan-binding lectin deficiency is associated with unexplained recurrent miscarriage. Scand J Immunol 1999; 49:193-196.
36. Kilpatrick DC: Human mannan binding protein in pre-eclampsia. Immunol Lett 1996; 49:175-177.
37. Kilpatrick DC, Starrs L, Moore S, Souter V, Liston WA: Mannan binding lectin concentration and risk of miscarriage. Hum Reprod 1999; 14:2379-2380.
38. Kruse C, Rosgaard A, Steffensen R, Varming K, Jensenius JC, Christiansen OB: Low serum level of mannan-binding lectin is a determinant for pregnancy outcome in women with recurrent spontaneous abortion. Am J Obstet Gynecol 2002; 187:1313-1320.
39. Van De Geijn FE, Dolhain RJ, Van Rijs W, Hazes JM, De Groot CJ: Mannose-binding lectin genotypes and pre-eclampsia: a case-control study. Hum Immunol 2007; 68:888-893.
40. Brown MA, Hague WM, Higgins J, Lowe S, McCowan L, Oats J, Peek MJ, Rowan JA, Walters BN: The detection, investigation and management of hypertension in pregnancy: executive summary. Aust N Z J Obstet Gynaecol 2000; 40:133-138.
41. Sibai BM: Diagnosis and management of gestational hypertension and preeclampsia. Obstet Gynecol 2003; 102:181-192.
42. Lahiri DK, Nurnberger JI Jr: A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res 1991; 19:5444.
43. Madsen HO, Satz ML, Hogh B, Svejgaard A, Garred P: Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America. J Immunol 1998; 161:3169-3175.
44. Frakking FN, Brouwer N, Zweers D, Merkus MP, Kuijpers TW, Offringa M, Dolman KM: High prevalence of mannose-binding lectin (MBL) deficiency in premature neonates. Clin Exp Immunol 2006; 145:5-12.
45. Than NG, Romero R, Erez O, Kusanovic JP, Tarca AL, Edwin SS, Kim JS, Hassan SS, Espinoza J, Mittal P, Mazaki-Tovi S, Friel L, Gotsch F, Vaisbuch E, Camacho N, Papp Z: A role for mannose-binding lectin, a component of the innate immune system in preeclampsia. Am J Reprod Immunol 2008; 60:333-345.