E3 ubiquitin ligase Cbl-b potentiates the apoptotic action of arsenic trioxide by inhibiting the PI3K/Akt pathway

Brazilian Journal of Medical and Biological Research

Volumn 44, Issue 2, 2011, Pages 105-111

  Li, Yingchun ^a   Qu, Xiujuan ^a   Qu, Jinglei ^a   Zhang, Ye ^a   Liu, Jing ^a   Teng, Yuee ^a   Hu, Xuejun ^b   Hou, Kezuo ^a   Liu, Yunpeng ^a  

^a Department of Medical Oncology ^*  (China)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Arsenic trioxide; Cbl b; PI3K Akt pathway

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ARSENIC TRIOXIDE; CBL PROTEIN; PHOSPHATIDYLINOSITOL; PROTEIN KINASE B INHIBITOR; TRYPAN BLUE; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL STRAIN HL 60; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; GENETIC TRANSFECTION; HEMATOLOGIC MALIGNANCY; HEMATOLOGY; IC 50; MAST CELL LEUKEMIA; MUTATION; NONHUMAN; PROTEIN EXPRESSION; RAT; UPREGULATION; WESTERN BLOTTING;

RATTUS;

EID: 79951497063     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2010007500142     Document Type: Article

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