Overexpression or knockdown of rat tryptophan hyroxylase-2 has opposing effects on anxiety behavior in an estrogen-dependent manner

Neuroscience

Volumn 176, Issue , 2011, Pages 120-131

  Hiroi, R ^a,b   McDevitt, R A ^a,b   Morcos, P A ^c   Clark, M S ^a   Neumaier, J F ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c Gene Tools LLC   (United States)

Author keywords

Estradiol; Gene transfer; Herpes virus vector; MRNA; Raphe; Serotonin

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; ESTROGEN; GREEN FLUORESCENT PROTEIN; HERPESVIRUS VECTOR; MESSENGER RNA; TRYPTOPHAN HYDROXYLASE 2;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; FEMALE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; MALE; NONHUMAN; OPEN FIELD TEST; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; QUANTITATIVE STUDY; RAT; TRANQUILIZING ACTIVITY;

ANIMALS; ANXIETY; ANXIETY DISORDERS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; ESTRADIOL; FEMALE; GENE KNOCKDOWN TECHNIQUES; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; OVARIECTOMY; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; TRYPTOPHAN HYDROXYLASE;

EID: 79851514894     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.12.019     Document Type: Article

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