Antinociception produced by Thalassia testudinum extract BM-21 is mediated by the inhibition of acid sensing ionic channels by the phenolic compound thalassiolin B

Molecular Pain

Volumn 7, Issue , 2011, Pages

  Garateix, Anoland ^a   Salceda, Emilio ^b   Menéndez, Roberto ^a   Regalado, Erik L ^a   López, Omar ^b   García, Teidy ^a   Morales, Ruth A ^a   Laguna, Abilio ^a   Thomas, Olivier P ^c   Soto, Enrique ^b  

^a Centro de Bioproductos Marinos   (Cuba)

^b BENEMÉRITA UNIVERSIDAD AUTÓNOMA DE PUEBLA   (Mexico)

^c UNIVERSITÉ CÔTE D'AZUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACID SENSING ION CHANNEL; BM 21; INDOMETACIN; PHENOL DERIVATIVE; PLANT EXTRACT; THALASSIA TESTUDINUM EXTRACT; THALASSIOLIN B; UNCLASSIFIED DRUG; AMILORIDE; ASIC CHANNEL; FLAVONOID; NERVE PROTEIN; PROTON; SODIUM CHANNEL;

ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG SELECTIVITY; ELECTRIC POTENTIAL; IN VITRO STUDY; IN VIVO STUDY; ION CURRENT; LICKING; MALE; MOUSE; NONHUMAN; PAIN; PH; PRIORITY JOURNAL; RAT; RESPONSE TIME; SEAGRASS; SPINAL GANGLION; THALASSIA TESTUDINUM; ANIMAL; CHANNEL GATING; CHEMISTRY; DRUG ANTAGONISM; DRUG MIXTURE; HYDROCHARITACEAE; METABOLISM; MOTOR ACTIVITY; NOCICEPTIVE RECEPTOR; PAIN ASSESSMENT; ROTAROD TEST; TEMPERATURE;

AMILORIDE; ANIMALS; COMPLEX MIXTURES; FLAVONOIDS; GANGLIA, SPINAL; HYDROCHARITACEAE; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; MALE; MICE; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; NOCICEPTORS; PAIN MEASUREMENT; PHENOLS; PLANT EXTRACTS; PROTONS; RATS; ROTAROD PERFORMANCE TEST; SODIUM CHANNELS; TEMPERATURE;

EID: 79851508372     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-7-10     Document Type: Article

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