Interactions of monoamine oxidases with the antiepileptic drug zonisamide: Specificity of inhibition and structure of the human monoamine oxidase B complex

Journal of Medicinal Chemistry

Volumn 54, Issue 3, 2011, Pages 909-912

  Binda, Claudia ^a   Aldeco, Milagros ^b   Mattevi, Andrea ^a   Edmondson, Dale E ^b  

^a UNIVERSITY OF PAVIA   (Italy)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; MONOAMINE OXIDASE A INHIBITOR; MONOAMINE OXIDASE B INHIBITOR; ZONISAMIDE;

ARTICLE; CATALYSIS; COMPETITIVE INHIBITION; DRUG ACTIVITY; DRUG BINDING; DRUG STRUCTURE; ENZYME BINDING; ENZYME INHIBITION; ENZYME SUBSTRATE; EPILEPSY; HUMAN; NONHUMAN; PARKINSON DISEASE; PROTEIN STRUCTURE; RAT;

ANIMALS; ANTICONVULSANTS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; ISOXAZOLES; MODELS, MOLECULAR; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; PROTEIN BINDING; PROTEIN CONFORMATION; RATS;

EID: 79851502469     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm101359c     Document Type: Article

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