Effects of TGF-β1 on gene expression of connective tissue growth factor in lung fibroblasts

Chinese Journal of Contemporary Pediatrics

Volumn 13, Issue 1, 2011, Pages 36-39

  Fu, Jian Hua ^a   Yang, Hai Ping ^a   Pan, Li ^a   Xue, Xin Dong ^a   Gao, Hong ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Connective tissue growth factor; Lung fibroblasts; Rats; Transforming growth factor 1

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; EMBRYO; FIBROBLAST CULTURE; GENE EXPRESSION; LUNG FIBROBLAST; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WISTAR RAT;

ANIMALS; CONNECTIVE TISSUE GROWTH FACTOR; FEMALE; FIBROBLASTS; GENE EXPRESSION; LUNG; PULMONARY FIBROSIS; RATS; RATS, WISTAR; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1;

EID: 79851486030     PISSN: 10088830     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Stenmark KR, Balasubramaniam V. Angiogenic therapy for bronchopulmonary dysplasia: rationale and promise [J]. Circulation, 2005, 112(16): 2383-2385. (Pubitemid 41504486)
2. Smith J. An update on bronchopulmonary dysplasia: is there a relationship to the development of childhood asthma? [J]. Med Hypotheses, 2003, 61(4): 495-502.
3. Kelleher MD, Naureckas ET, Solway J, Hershenson MB. In vivo hyperoxic exposure increases cultured lung fibroblast proliferation and c-Ha-ras expression [J]. Am J Respir Cell Mol boil, 1995, 12(1): 19-26.
4. Lai TC, Pociask DA, Ferris M, Nguyen HT, Miller CA 3rd, Brody A, et al. Small interfering RNAs (siRNAs) targeting TGF-beta1 mRNA suppress asbestos-induced expression of TGF-beta1 and CTGF in fibroblasts [J]. J Environ Pathol Toxicol Oncol, 2009, 28(2): 109-119.
5. Bradham DM, Igarashi A, Potter RL, Grotendorst GR. Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10 [J]. J Cell Biol, 1991, 114(6): 1285-1294. (Pubitemid 21909886)
6. Dziadzio M, Usinger W, Leask A, Abraham D, Black CM, Denton C, et al. N-terminal connective tissue growth factor is a marker of the fibrotic phenotype in scleroderma [J]. QJM, 2005, 98(7): 485-492.
7. Bonniaud P, Martin G, Margetts PJ, Ask K, Robertson J, Gauldie J, et al. Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis resistant" BALB/c mouse lungs [J]. Am J Respir Cell Mol Biol, 2004, 31(5): 510-516.
8. Ogawa E, Elliott WM, Hughes F, Eichholtz TJ, Hogg JC, Hayashi S. Latent adenoviral infection induces production of growth factor relevant to airway remodeling in COPD [J]. Am J Physiol Lung Cell Mol Physiol, 2004, 286(1): L189-L197. (Pubitemid 38055875)
9. Abou-Shady M, Friess H, Zimmermann A, di Mola FF, Guo XZ, Baer HU, et al. Connective tissue growth factor in human liver cirrhosis [J]. Liver, 2000, 20(4): 296-304. (Pubitemid 30488001)
10. Zhou G, Li C, Cai L. Advanced glycation end-products induce connective tissue growth factor-mediated renal fibrosis predominantly through transforming growth factor beta-independent pathway [J]. Am J Pathol, 2004, 165(6): 2033-2043. (Pubitemid 39578381)
11. Brigstock DR. Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals [J]. J Cell Commun Signal, 2010, 4(1): 14.
12. Yokoi H, Mukoyama M, Sugawara A, Mori K, Nagae T, Makino H, et al. Role of connective tissue growth factor in fibronectin expression and tubulointerstitial fibrosis [J]. Am J Physiol Renal Physiol, 2002, 282(5): F933-F942. (Pubitemid 34654499)
13. Chen CM, Wang LF, Chou HC, Lang YD, Lai YP. Up-regulation of connective tissue growth factor in hyperoxia-induced lung fibrosis [J]. Pediatr Rse, 2007, 62(2): 128-133.
14. Tung JN, Lang YD, Wang LF, Chen CM. Paraquat increases connective tissue growth factor and collagen expression via angiotensin signaling pathway in human lung fibroblasts [J]. Toxicol In Vitro, 2010, 24(3): 803-808.