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Volumn 9, Issue 1, 2011, Pages

Common disease: Are causative alleles common or rare?

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

EID: 79851472702     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001009     Document Type: Editorial
Times cited : (11)

References (9)
  • 1
    • 0035451780 scopus 로고    scopus 로고
    • On the allelic spectrum of human disease
    • Reich D. E, Lander E. S (2001) On the allelic spectrum of human disease. Trends Genet 17: 502-510.
    • (2001) Trends Genet , vol.17 , pp. 502-510
    • Reich, D.E.1    Lander, E.S.2
  • 2
    • 0036137130 scopus 로고    scopus 로고
    • Linkage disequilibrium and the mapping of complex human traits
    • Weiss K. M, Clark A. G (2002) Linkage disequilibrium and the mapping of complex human traits Trends Genet 18: 19-24.
    • (2002) Trends Genet , vol.18 , pp. 19-24
    • Weiss, K.M.1    Clark, A.G.2
  • 3
    • 0034969437 scopus 로고    scopus 로고
    • Are rare variants responsible for susceptibility to complex diseases?
    • Pritchard J. K (2001) Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet 69: 124-137.
    • (2001) Am J Hum Genet , vol.69 , pp. 124-137
    • Pritchard, J.K.1
  • 4
    • 78049407733 scopus 로고    scopus 로고
    • Genomics: the search for association
    • Baker M (2010) Genomics: the search for association. Nature 467: 1135-1138.
    • (2010) Nature , vol.467 , pp. 1135-1138
    • Baker, M.1
  • 5
    • 77249134594 scopus 로고    scopus 로고
    • Rare variants create synthetic genome-wide associations
    • doi: 10.1371/journal.pbio.1000294
    • Dickson S. P, Wang K, Krantz I, Hakonarson H, Goldstein D. B (2010) Rare variants create synthetic genome-wide associations. PLoS Biol 8: e1000294 doi:10.1371/journal.pbio.1000294.
    • (2010) PLoS Biol , vol.8
    • Dickson, S.P.1    Wang, K.2    Krantz, I.3    Hakonarson, H.4    Goldstein, D.B.5
  • 6
    • 78650603522 scopus 로고    scopus 로고
    • Genes show limited value in predicting disease
    • Available:. Accessed 10 December 2010, 15 April
    • Wade N (15 April 2009) Genes show limited value in predicting disease. The New York Times Available: http://www.nytimes.com/2009/04/16/health/research/16gene.html. Accessed 10 December 2010.
    • (2009) The New York Times
    • Wade, N.1
  • 7
    • 79851487367 scopus 로고    scopus 로고
    • Synthetic associations created by rare variants do not explain most GWAS results
    • doi: 10.1371/journal.pbio.1000579
    • Wray N. R, Purcell S. M, Visscher P. M (2011) Synthetic associations created by rare variants do not explain most GWAS results. PLoS Biol 9: e1000579 doi:10.1371/journal.pbio.1000579.
    • (2011) PLoS Biol , vol.9
    • Wray, N.R.1    Purcell, S.M.2    Visscher, P.M.3
  • 8
    • 79851468862 scopus 로고    scopus 로고
    • Synthetic associations are unlikely to account for many common disease genome-wide association signals
    • doi: 10.1371/journal.pbio.1000580
    • Anderson C. A, Soranzo N, Zeggini E, Barrett J. C (2011) Synthetic associations are unlikely to account for many common disease genome-wide association signals. PLoS Biol 9: e1000580 doi:10.1371/journal.pbio.1000580.
    • (2011) PLoS Biol , vol.9
    • Anderson, C.A.1    Soranzo, N.2    Zeggini, E.3    Barrett, J.C.4
  • 9
    • 79851487366 scopus 로고    scopus 로고
    • The importance of synthetic associations will only be resolved empirically
    • doi: 10.1371/journal.pbio.1001008
    • Goldstein D. B (2011) The importance of synthetic associations will only be resolved empirically. PLoS Biol 9: e1001008 doi:10.1371/journal.pbio.1001008.
    • (2011) PLoS Biol , vol.9
    • Goldstein, D.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.