-
1
-
-
0033614446
-
Chronic myeloid leukemia
-
Apr 29
-
Sawyers CL. Chronic myeloid leukemia. N Engl J Med. 1999 Apr 29;340(17):1330-40.
-
(1999)
N Engl J Med.
, vol.340
, Issue.17
, pp. 1330-1340
-
-
Sawyers, C.L.1
-
2
-
-
0033565561
-
The biology of chronic myeloid leukemia
-
Jul 15
-
Faderl S, Talpaz M, Estrov Z, O'Brien S, Kurzrock R, Kantarjian HM. The biology of chronic myeloid leukemia. N Engl J Med. 1999 Jul 15;341(3):164-72.
-
(1999)
N Engl J Med.
, vol.341
, Issue.3
, pp. 164-172
-
-
Faderl, S.1
Talpaz, M.2
Estrov, Z.3
O'Brien, S.4
Kurzrock, R.5
Kantarjian, H.M.6
-
3
-
-
0015694748
-
Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
-
Jun 1
-
Rowley JD. Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature. 1973 Jun 1;243(5405):290-3.
-
(1973)
Nature
, vol.243
, Issue.5405
, pp. 290-293
-
-
Rowley, J.D.1
-
4
-
-
0021811764
-
Structural organization of the bcr gene and its role in the Ph' translocation
-
Jun 27-Jul 3
-
Heisterkamp N, Stam K, Groffen J, de Klein A, Grosveld G. Structural organization of the bcr gene and its role in the Ph' translocation. Nature. 1985 Jun 27-Jul 3;315(6022):758-61.
-
(1985)
Nature
, vol.315
, Issue.6022
, pp. 758-761
-
-
Heisterkamp, N.1
Stam, K.2
Groffen, J.3
de Klein, A.4
Grosveld, G.5
-
5
-
-
0025348013
-
Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
-
Mar 2
-
Lugo TG, Pendergast AM, Muller AJ, Witte ON. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science. 1990 Mar 2;247(4946):1079-82.
-
(1990)
Science
, vol.247
, Issue.4946
, pp. 1079-1082
-
-
Lugo, T.G.1
Pendergast, A.M.2
Muller, A.J.3
Witte, O.N.4
-
6
-
-
0038100233
-
Molecular mechanisms of transformation by the BCR-ABL oncogene
-
Apr
-
Sattler M, Griffin JD. Molecular mechanisms of transformation by the BCR-ABL oncogene. Semin Hematol. 2003 Apr;40(2 Suppl 2):4-10.
-
(2003)
Semin Hematol.
, vol.40
, Issue.2 SUPPL 2
, pp. 4-10
-
-
Sattler, M.1
Griffin, J.D.2
-
7
-
-
0042360542
-
Chronic myeloid leukemia: Pathophysiology, diagnostic parameters, and current treatment concepts
-
Aug 14
-
Sillaber C, Mayerhofer M, Agis H, et al. Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts. Wien Klin Wochenschr. 2003 Aug 14;115(13-14):485-504.
-
(2003)
Wien Klin Wochenschr.
, vol.115
, Issue.13-14
, pp. 485-504
-
-
Sillaber, C.1
Mayerhofer, M.2
Agis, H.3
-
8
-
-
0025117392
-
Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome
-
Feb 16
-
Daley GQ, van Etten RA, Baltimore D. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science. 1990 Feb 16;247(4944):824-30.
-
(1990)
Science
, vol.247
, Issue.4944
, pp. 824-830
-
-
Daley, G.Q.1
van Etten, R.A.2
Baltimore, D.3
-
9
-
-
72149087674
-
NCCN clinical practice guidelines in oncology: Chronic myelogenous leukemia
-
Oct
-
O'Brien S, Berman E, Borghaei H, et al. NCCN clinical practice guidelines in oncology: chronic myelogenous leukemia. J Natl Compr Canc Netw. 2009 Oct;7(9):984-1023.
-
(2009)
J Natl Compr Canc Netw.
, vol.7
, Issue.9
, pp. 984-1023
-
-
O'Brien, S.1
Berman, E.2
Borghaei, H.3
-
10
-
-
73349122639
-
Chronic myeloid leukemia: An update of concepts and management recommendations of European LeukemiaNet
-
Dec 10
-
Baccarani M, Cortes J, Pane F, et al. Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet. J Clin Oncol. 2009 Dec 10;27(35):6041-51.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.35
, pp. 6041-6051
-
-
Baccarani, M.1
Cortes, J.2
Pane, F.3
-
11
-
-
77949767505
-
International randomized study of interferon vs. STI571 (IRIS) 8-year follow up: Sustained survival and low risk for progression of events in patients with newly diagnosed chronic lymphocytic leukemia in chronic phase (CML-CP) treated with imatinib
-
(abstr)
-
Deininger M, O'Brien SG, Guilhot F, et al. International randomized study of interferon vs. STI571 (IRIS) 8-year follow up: sustained survival and low risk for progression of events in patients with newly diagnosed chronic lymphocytic leukemia in chronic phase (CML-CP) treated with imatinib. Blood (ASH Annual Meeting Abstracts). 2009;114(462): (abstr 1126).
-
(2009)
Blood (ASH Annual Meeting Abstracts)
, vol.114
, Issue.462
, pp. 1126
-
-
Deininger, M.1
O'Brien, S.G.2
Guilhot, F.3
-
12
-
-
45149087139
-
Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib
-
Jun
-
Hochhaus A, Baccarani M, Deininger M, et al. Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib. Leukemia. 2008 Jun;22(6):1200-6.
-
(2008)
Leukemia
, vol.22
, Issue.6
, pp. 1200-1206
-
-
Hochhaus, A.1
Baccarani, M.2
Deininger, M.3
-
13
-
-
41349123259
-
Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: Practical advice on the use and interpretation of monitoring methods
-
Feb 15
-
Kantarjian H, Schiffer C, Jones D, Cortes J. Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: practical advice on the use and interpretation of monitoring methods. Blood. 2008 Feb 15;111(4):1774-80.
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 1774-1780
-
-
Kantarjian, H.1
Schiffer, C.2
Jones, D.3
Cortes, J.4
-
14
-
-
13844251975
-
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
-
Feb
-
Weisberg E, Manley PW, Breitenstein W. Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer Cell. 2005 Feb;7(2):129-41.
-
(2005)
Cancer Cell
, vol.7
, Issue.2
, pp. 129-141
-
-
Weisberg, E.1
Manley, P.W.2
Breitenstein, W.3
-
15
-
-
21144451094
-
In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants
-
Jun 1
-
O'Hare T, Walters DK, Stoffregen EP. In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. Cancer Res. 2005 Jun 1;65(11):4500-5.
-
(2005)
Cancer Res.
, vol.65
, Issue.11
, pp. 4500-4505
-
-
O'Hare, T.1
Walters, D.K.2
Stoffregen, E.P.3
-
16
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
Jul 16
-
Shah NP, Tran C, Lee FY, Chen P, Norris D, Sawyers CL. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science. 2004 Jul 16;305(5682):399-401.
-
(2004)
Science
, vol.305
, Issue.5682
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
Chen, P.4
Norris, D.5
Sawyers, C.L.6
-
17
-
-
33745283618
-
The structure of Dasatinib (BMS- 354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants
-
Jun 1
-
Tokarski JS, Newitt JA, Chang CY, et al. The structure of Dasatinib (BMS- 354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants. Cancer Res. 2006 Jun 1;66(11):5790-7.
-
(2006)
Cancer Res.
, vol.66
, Issue.11
, pp. 5790-5797
-
-
Tokarski, J.S.1
Newitt, J.A.2
Chang, C.Y.3
-
18
-
-
67749135477
-
New dosing schedules of dasatinib for CML and adverse event management
-
Wong SF. New dosing schedules of dasatinib for CML and adverse event management. J Hematol Oncol. 2009;2:10.
-
(2009)
J Hematol Oncol.
, vol.2
, pp. 10
-
-
Wong, S.F.1
-
19
-
-
34248324467
-
Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or - intolerant chronic myeloid leukemia in accelerated phase
-
May 15
-
Guilhot F, Apperley J, Kim DW, et al. Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or - intolerant chronic myeloid leukemia in accelerated phase. Blood. 2007 May 15;109(10):4143-50.
-
(2007)
Blood
, vol.109
, Issue.10
, pp. 4143-4150
-
-
Guilhot, F.1
Apperley, J.2
Kim, D.W.3
-
20
-
-
34948829146
-
Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: Interim results of a phase 2 study
-
Oct 1
-
Ottmann O, Dombret H, Martinelli G, et al. Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: interim results of a phase 2 study. Blood. 2007 Oct 1;110(7):2309-15.
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2309-2315
-
-
Ottmann, O.1
Dombret, H.2
Martinelli, G.3
-
21
-
-
76549116248
-
Potent, transient inhibition of BCRABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib
-
Feb
-
Shah NP, Kim DW, Kantarjian H, et al. Potent, transient inhibition of BCRABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib. Haematologica. 2010 Feb;95(2):232-40.
-
(2010)
Haematologica
, vol.95
, Issue.2
, pp. 232-240
-
-
Shah, N.P.1
Kim, D.W.2
Kantarjian, H.3
-
22
-
-
37349115522
-
Dasatinib 140 mg QD vs. 70 mg BID in advanced-phase CML or PhBBALL resistant or intolerant to imatinib: Results from a randomized, Phase-III trial (CA180035)
-
(Proceedings Presented at 12th Congress of the European Hematology Association)
-
Dombret H, Ottmann O, Goh Y, et al. Dasatinib 140 mg QD vs. 70 mg BID in advanced-phase CML or PhBBALL resistant or intolerant to imatinib: results from a randomized, Phase-III trial (CA180035). Haematologica. 2007;92(Suppl 1):319. (Proceedings Presented at 12th Congress of the European Hematology Association).
-
(2007)
Haematologica
, vol.92
, Issue.SUPPL 1
, pp. 319
-
-
Dombret, H.1
Ottmann, O.2
Goh, Y.3
-
24
-
-
77953725855
-
Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
-
Jun 17
-
Kantarjian H, Shah NP, Hochhaus A, et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2010 Jun 17;362(24):2260-70.
-
(2010)
N Engl J Med.
, vol.362
, Issue.24
, pp. 2260-2270
-
-
Kantarjian, H.1
Shah, N.P.2
Hochhaus, A.3
-
25
-
-
77951671751
-
Imatinib-induced pancreatitis
-
Feb
-
Varma MR, Mathew S, Krishnadas D, Vinayakumar KR. Imatinib-induced pancreatitis. Indian J Pharmacol. 2010 Feb;42(1):50-2.
-
(2010)
Indian J Pharmacol.
, vol.42
, Issue.1
, pp. 50-52
-
-
Varma, M.R.1
Mathew, S.2
Krishnadas, D.3
Vinayakumar, K.R.4
-
26
-
-
73149123364
-
Pancreatic enzyme elevation in chronic myeloid leukemia patients treated with nilotinib after imatinib failure
-
Dec
-
Palandri F, Castagnetti F, Soverini S, et al. Pancreatic enzyme elevation in chronic myeloid leukemia patients treated with nilotinib after imatinib failure. Haematologica. 2009 Dec;94(12):1758-61.
-
(2009)
Haematologica
, vol.94
, Issue.12
, pp. 1758-1761
-
-
Palandri, F.1
Castagnetti, F.2
Soverini, S.3
-
27
-
-
36348968931
-
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance
-
Nov 15
-
Kantarjian HM, Giles F, Gattermann N, et al. Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance. Blood. 2007 Nov 15;110(10):3540-6.
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3540-3546
-
-
Kantarjian, H.M.1
Giles, F.2
Gattermann, N.3
-
28
-
-
41349083969
-
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or -intolerant accelerated-phase chronic myelogenous leukemia
-
Feb 15
-
Le Coutre P, Ottmann OG, Giles F, et al. Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or -intolerant accelerated-phase chronic myelogenous leukemia. Blood. 2008 Feb 15;111(4):1834-9.
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 1834-1839
-
-
le Coutre, P.1
Ottmann, O.G.2
Giles, F.3
-
29
-
-
53049083618
-
Tasigna for chronic and accelerated phase Philadelphia chromosome-positive chronic myelogenous leukemia resistant to or intolerant of imatinib
-
Sep 1
-
Hazarika M, Jiang X, Liu Q, et al. Tasigna for chronic and accelerated phase Philadelphia chromosome-positive chronic myelogenous leukemia resistant to or intolerant of imatinib. Clin Cancer Res. 2008 Sep 1;14(17):5325-31.
-
(2008)
Clin Cancer Res.
, vol.14
, Issue.17
, pp. 5325-5331
-
-
Hazarika, M.1
Jiang, X.2
Liu, Q.3
-
30
-
-
77954612906
-
Clinical impact of dose reductions and interruptions of second-generation tyrosine kinase inhibitors in patients with chronic myeloid leukaemia
-
Aug
-
Santos FP, Kantarjian H, Fava C, et al. Clinical impact of dose reductions and interruptions of second-generation tyrosine kinase inhibitors in patients with chronic myeloid leukaemia. Br J Haematol. 2010 Aug;150(3):303-12.
-
(2010)
Br J Haematol.
, vol.150
, Issue.3
, pp. 303-312
-
-
Santos, F.P.1
Kantarjian, H.2
Fava, C.3
-
31
-
-
35349001079
-
Lung abnormalities after dasatinib treatment for chronic myeloid leukemia: A case series
-
Oct 15
-
Bergeron A, Rea D, Levy V, et al. Lung abnormalities after dasatinib treatment for chronic myeloid leukemia: a case series. Am J Respir Crit Care Med. 2007 Oct 15;176(8):814-8.
-
(2007)
Am J Respir Crit Care Med.
, vol.176
, Issue.8
, pp. 814-818
-
-
Bergeron, A.1
Rea, D.2
Levy, V.3
-
32
-
-
70349154648
-
Efficacy of dasatinib in a chronic myeloid leukemia patient with disease molecular relapse and chronic GVHD after haploidentical BMT: An immunomodulatory effect?
-
Sep
-
Breccia M, Cannella L, Stefanizzi C, Carotti A, Santopietro M, Alimena G. Efficacy of dasatinib in a chronic myeloid leukemia patient with disease molecular relapse and chronic GVHD after haploidentical BMT: an immunomodulatory effect? Bone Marrow Transplant. 2009 Sep;44(5):331-2.
-
(2009)
Bone Marrow Transplant
, vol.44
, Issue.5
, pp. 331-332
-
-
Breccia, M.1
Cannella, L.2
Stefanizzi, C.3
Carotti, A.4
Santopietro, M.5
Alimena, G.6
-
33
-
-
77955269560
-
Successful treatment using low-dose dasatinib for chronic myelogenous leukemia in a patient with megakaryoblastic transformation concomitant with myelofibrosis and an extramedullary tumor
-
Sep
-
Yamaguchi M, Munemoto S, Kasada A, Murata R, Ueda M. Successful treatment using low-dose dasatinib for chronic myelogenous leukemia in a patient with megakaryoblastic transformation concomitant with myelofibrosis and an extramedullary tumor. Leuk Res. 2010 Sep;34(9):e237-9.
-
(2010)
Leuk Res.
, vol.34
, Issue.9
-
-
Yamaguchi, M.1
Munemoto, S.2
Kasada, A.3
Murata, R.4
Ueda, M.5
|