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Volumn 44, Issue 5, 2009, Pages 331-332

Efficacy of dasatinib in a chronic myeloid leukemia patient with disease molecular relapse and chronic GVHD after haploidentical BMT: An immunomodulatory effect?

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BCR ABL PROTEIN; CYCLOSPORIN A; DASATINIB; HLA A2 ANTIGEN; HYDROXYUREA; IMATINIB; MERCAPTOPURINE;

EID: 70349154648     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2009.20     Document Type: Article
Times cited : (10)

References (8)
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    • Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukaemia in chronic phase with resistance or intolerance to imatinib
    • Hochhaus A, Baccarani M, Deininger M, Apperley J, Lipton JH, Goldberg SL et al. Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukaemia in chronic phase with resistance or intolerance to imatinib. Leukemia 2008; 22: 1200-1206.
    • (2008) Leukemia , vol.22 , pp. 1200-1206
    • Hochhaus, A.1    Baccarani, M.2    Deininger, M.3    Apperley, J.4    Lipton, J.H.5    Goldberg, S.L.6
  • 3
    • 38949210227 scopus 로고    scopus 로고
    • Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation
    • Schade AE, Schieven GL, Townsend R, Jankowska AM, Susulic V, Zhang R et al. Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation. Blood 2008; 111 1366-1377.
    • (2008) Blood , vol.111 , pp. 1366-1377
    • Schade, A.E.1    Schieven, G.L.2    Townsend, R.3    Jankowska, A.M.4    Susulic, V.5    Zhang, R.6
  • 4
    • 15244351682 scopus 로고    scopus 로고
    • Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner
    • Seggewiss R, Lorè K, Greiner E, Magnusson MK, Price DA, Douek DC et al. Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner. Blood 2005; 105: 2473-2479.
    • (2005) Blood , vol.105 , pp. 2473-2479
    • Seggewiss, R.1    Lorè, K.2    Greiner, E.3    Magnusson, M.K.4    Price, D.A.5    Douek, D.C.6
  • 5
    • 45749156098 scopus 로고    scopus 로고
    • EBMT Paediatric Working Party. Acute GVHD: Pathogenesis and classification
    • Ball LM, Egeler RM, EBMT Paediatric Working Party. Acute GVHD: pathogenesis and classification. Bone Marrow Transplant 2008; 41(Suppl 2): S58-S64.
    • (2008) Bone Marrow Transplant , vol.41 , Issue.SUPPL. 2
    • Ball, L.M.1    Egeler, R.M.2
  • 6
    • 52049085750 scopus 로고    scopus 로고
    • Dasatinib exerts an immunosuppressive effect on CD8+ T cells specific for viral and leukaemia antigens
    • Fei F, Yu Y, Schmitt A, Rojewski MT, Chen B, Greiner J et al. Dasatinib exerts an immunosuppressive effect on CD8+ T cells specific for viral and leukaemia antigens. Exp Hematol 2008; 36: 1297-1308.
    • (2008) Exp Hematol , vol.36 , pp. 1297-1308
    • Fei, F.1    Yu, Y.2    Schmitt, A.3    Rojewski, M.T.4    Chen, B.5    Greiner, J.6
  • 7
    • 70349095353 scopus 로고    scopus 로고
    • Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
    • Abstract
    • Mustjoki S, Ekblom M, Petteri Arstila T, Dybedal I, Epling-Burnette PK, Garzon F et al. Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy. Blood 2008; 112: 215 (Abstract no. 573).
    • (2008) Blood , vol.112 , Issue.573 , pp. 215
    • Mustjoki, S.1    Ekblom, M.2    Petteri Arstila, T.3    Dybedal, I.4    Epling-Burnette, P.K.5    Garzon, F.6
  • 8
    • 34248166041 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukaemia cells
    • Nam S, Wiliams A, Vultur A, List A, Bhalla K, Smith D et al. Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukaemia cells. Mol Cancer Ther 2007; 6: 1400-1405.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1400-1405
    • Nam, S.1    Wiliams, A.2    Vultur, A.3    List, A.4    Bhalla, K.5    Smith, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.