Change in cytokine levels after administration of saikokaryuukotsuboreito or testosterone in patients with symptoms of late-onset hypogonadism

Aging Male

Volumn 14, Issue 1, 2011, Pages 76-81

  Tsujimura, Akira ^a   Miyagawa, Yasushi ^a   Okuda, Hidenobu ^a   Yamamoto, Keisuke ^a   Fukuhara, Shinichiro ^a   Nakayama, Jiro ^a   Takao, Tetsuya ^a   Nonomura, Norio ^a   Okuyama, Akihiko ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cytokine; LOH; saikokaryukotsuboreito; testosterone replacement

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; SAIKO KA RYUKOTSU BOREI TO; TESTOSTERONE; TESTOSTERONE ENANTATE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADULT; AGING MALE SYMPTOMS SCALE; ANDROGEN THERAPY; ARTICLE; CLINICAL ARTICLE; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DRUG EFFICACY; HUMAN; HYPOGONADISM; LATE ONSET HYPOGONADISM; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; TESTOSTERONE BLOOD LEVEL;

ADULT; AGE FACTORS; AGED; AGING; ANDROGENS; CYTOKINES; DRUGS, CHINESE HERBAL; HEALTH STATUS INDICATORS; HORMONE REPLACEMENT THERAPY; HUMANS; HYPOGONADISM; INTERLEUKIN-13; INTERLEUKIN-8; MALE; MEDICINE, KAMPO; MIDDLE AGED; PROSPECTIVE STUDIES; QUESTIONNAIRES; TESTOSTERONE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79751503954     PISSN: 13685538     EISSN: 14730790     Source Type: Journal    
DOI: 10.3109/13685538.2010.502268     Document Type: Article

References (40)

1. Wang C, Nieschlag E, Swerdloff RS, Behre H, Hellstrom WJ, Gooren LJ, Kaufman JM, Legros JJ, Lunenfeld B, Morales A, et al. ISA, ISSAM, EAU, EAA and ASA recommendations: investigation, treatment and monitoring of late-onset hypogonadism in males. Aging Male 2009;12:5-12.
2. Morales A, Buvat J, Gooren LJ, Guay AT, Kaufman JM, Tan HM, Torres LO. Endocrine aspects of sexual dysfunction in men. J Sex Med 2004;1:69-81. (Pubitemid 40424669)
3. Comhaire FH. Andropause: hormone replacement therapy in the ageing male. Eur Urol 2000;38:655-662.
4. Morales A, Johnston B, Heaton JP, Lundie M. Testosterone supplementation for hypogonadal impotence: assessment of biochemical measures and therapeutic outcomes. J Urol 1997;157:849-854. (Pubitemid 27066265)
5. Morley JE. Testosterone replacement and the physiologic aspects of aging in men. Mayo Clin Proc 2000;75 (Suppl):S83-S87.
6. Morley JE. Testosterone replacement in older men and women. J Gend Specif Med 2001;4:49-53. (Pubitemid 34023963)
7. Morley JE, Perry HM III. Androgen treatment of male hypogonadism in older males. J Steroid Biochem Mol Biol 2003;85:367-373. (Pubitemid 37011112)
8. Tsujimura A, Matsumiya K, Miyagawa Y, Takao T, Fujita K, Takada S, Koga M, Iwasa A, Takeyama M, Okuyama A. Comparative study on evaluation methods for serum testosterone level for PADAM diagnosis. Int J Impot Res 2005;17:259-263. (Pubitemid 40675509)
9. Tsujimura A, Takada S, Matsuoka Y, Nakayama J, Takao T, Miyagawa Y, Nonomura N, Okuyama A. Clinical trial of treatment with saikokaryukotsuboreito for eugonadal patients with late-inset hypogonadism-related symptoms. Aging Male 2008;11:95-99. (Pubitemid 351878780)
10. Heinemann LA, Zimmermann T, Vermeulen A, Thiel C. A new 'aging males' symptoms' (AMS) rating scale. Aging Male 1999;2:105-114. (Pubitemid 29411279)
11. Amano T, Imao T, Takemae K. Clinical efficacy of Japanese traditional herbal medicine (Kampo) in patients with lateonset hypogonadism. Aging Male, in press. [Epub ahead of print].
12. Ushiroyama T, Ikeda A, Sakuma K, Ueki M. Changes in serum tumor necrosis factor (TNF-a) with kami-shoyo-san administration in depressed climacteric patients. Am J Chin Med 2004;32:621-629. (Pubitemid 39302679)
13. Ushiroyama T, Ikeda A, Sakuma K, Ueki M. Chai-hu-gui-zhigan- jiang-tang regulates plasma interleukin-6 and soluble interleukin-6 receptor concentrations and improves depressed mood in climacteric women with insomnia. Am J Chin Med 2005;33:703-711. (Pubitemid 41319920)
14. Namiki M, Akaza H, Shimazui T, Ito N, Iwamoto T, Baba K, Kumano H, Koh E, Tsujimura A, Matsumiya K, et al. Clinical practice manual for late-onset hypogonadism syndrome. Int J Urol 2008;15:377-388. (Pubitemid 351623887)
15. Morales A, Lunenfeld B. Investigation, treatment and monitoring of late-onset hypogonadism in males. Official recommendations of ISSAM. International Society for the Study of the Aging Male. Aging Male 2002;5:74-86.
16. Amory JK, Watts NB, Easley KA, Sutton PR, Anawalt BD, Matsumoto AM, Bremner WJ, Tenover JL. Exogenous testosterone or testosterone with finasteride increases bone mineral density in older men with low serum testosterone. J Clin Endocrinol Metab 2004;89:503-510. (Pubitemid 38269849)
17. Page ST, Amory JK, Bowman FD, Anawalt BD, Matsumoto AM, Bremner WJ, Tenover JL. Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T. J Clin Endocrinol Metab 2005;90:1502-1510. (Pubitemid 40464011)
18. Vaughan C, Goldstein FC, Tenover JL. Exogenous testosterone alone or with finasteride does not improve measurements of cognition in healthy older men with low serum testosterone. J Androl 2007;28:875-882. (Pubitemid 350058138)
19. Tsujimura A, Matsumiya K, Takao T, Miyagawa Y, Takada S, Koga M, Iwasa A, Takeyama M, Okuyama A. Treatment with human chorionic gonadotropin for PADAM: a preliminary report. Aging Male 2005;8:175-179. (Pubitemid 43068308)
20. Baggiolini M, Loetscher P, Moser B. Interleukin-8 and the chemokine family. Int J Immunopharmacol 1995;17:103-108.
21. Bruun JM, Pedersen SB, Richelsen B. Interleukin-8 production in human adipose tissue. inhibitory effects of anti-diabetic compounds, the thiazolidinedione ciglitazone and the biguanide metformin. Horm Metab Res 2000;32:537-541. (Pubitemid 32176083)
22. Bruun JM, Pedersen SB, Richelsen B. Regulation of interleukin 8 production and gene expression in human adipose tissue in vitro. J Clin Endocrinol Metab 2001;86: 1267-1273. (Pubitemid 32323015)
23. Zozulinska D, Majchrzak A, Sobieska M, Wiktorowicz K, Wierusz-Wysocka B. Serum interleukin-8 level is increased in diabetic patients. Diabetologia 1999;42:117-118. (Pubitemid 29039749)
24. Straczkowski M, Dzienis-Straczkowska S, Stepien A, Kowalska I, Szelachowska M, Kinalska I. Plasma interleukin-8 concentrations are increased in obese subjects and related to fat mass and tumor necrosis factor-a system. J Clin Endocrinol Metab 2002;87:4602-4606. (Pubitemid 35247047)
25. Bruun JM, Verdich C, Toubro S, Astrup A, Richelsen B. Association between measures of insulin sensitivity and circulating levels of interleukin-8, interleukin-6 and tumor necrosis factor-a. Effect of weight loss in obese men. Eur J Endocrinol 2003;148:535-542. (Pubitemid 36622161)
26. de Mello VD, Kolehmainen M, Schwab U, Mager U, Laaksonen DE, Pulkkinen L, Niskanen L, Gylling H, Atalay M, Rauramaa R, et al. Effect of weight loss on cytokine messenger RNA expression in peripheral blood mononuclear cells of obese subjects with the metabolic syndrome. Metabolism 2008;57:192-199.
27. Fattouh R, Jordana M. TGF-b, eosinophils and IL-13 in allergic airway remodeling: a critical appraisal with therapeutic considerations. Inflamm Allergy Drug Targets 2008;7:224-236.
28. Blease K. Therapeutics targeting IL-13 for the treatment of pulmonary inflammation and airway remodeling. Curr Opin Investig Drugs 2008;9:1180-1184.
29. Kasaian MT, Miller DK. IL-13 as a therapeutic target for respiratory disease. Biochem Pharmacol 2008;76:147-155.
30. Kuperman DA, Schleimer RP. Interleukin-4, interleukin-13, signal transducer and activator of transcription factor 6, and allergic asthma. Curr Mol Med 2008;8:384-392.
31. Eskandari F, Martinez PE, Torvik S, Phillips TM, Sternberg EM, Mistry S, Ronsaville D, Wesley R, Toomey C, Sebring NG, et al. Low bone mass in premenopausal women with depression. Arch Intern Med 2007;167:2329-2336. (Pubitemid 350179528)
32. Schiepers OJ, Wichers MC, Maes M. Cytokines and major depression. Prog Neuropsychopharmacol Biol Psychiatry 2005;29:201-217. (Pubitemid 40202906)
33. Breuil V, Ticchioni M, Testa J, Roux CH, Ferrari P, Breittmayer JP, Albert-Sabonnadiere C, Durant J, De Perreti F, Bernard A, et al. Immune changes in post-menopausal osteoporosis: the Immunos study. Osteoporos Int, in press. [Epub ahead of print].
34. Billiau A, Matthys P. Interferon-g: a historical perspective. Cytokine Growth Factor Rev 2009;20:97-113.
35. Rothwell NJ, Hopkins SJ. Cytokines and the nervous system. II. Actions and mechanisms of action. Trends Neurosci 1995;18:130-136.
36. Vitkovic L, Bockaert J, Jacque C. "Inflammatory" cytokines: neuromodulators in normal brain? J Neurochem 2000;74: 457-471. (Pubitemid 30053717)
37. Brebner K, Hayley S, Zacharko R, Merali Z, Anisman H. Synergistic effects of interleukin-1b, interleukin-6, and tumor necrosis factor-a: central monoamine, corticosterone, and behavioral variations. Neuropsychopharmacology 2000;22: 566-580. (Pubitemid 30219401)
38. Haack M, Hinze-Selch D, Fenzel T, Kraus T, Kuhn M, Schuld A, Pollmacher T. Plasma levels of cytokines and soluble cytokine receptors in psychiatric patients upon hospital admission: effects of confounding factors and diagnosis. J Psychiatr Res 1999;33:407-418. (Pubitemid 29392689)
39. Weizman R, Laor N, Podliszewski E, Notti I, Djaldetti M, Bessler H. Cytokine production in major depressed patients before and after clomipramine treatment. Biol Psychiatry 1994;35:42-47. (Pubitemid 24063274)
40. Gabbay V, Klein RG, Guttman LE, Babb JS, Alonso CM, Nishawala M, Katz Y, Gaite MR, Gonzalez CJ. A preliminary study of cytokines in suicidal and nonsuicidal adolescents with major depression. J Child Adolesc Psychopharmacol 2009;19: 423-430.