-
1
-
-
0036527429
-
Protein kinases - The major drug targets of the twenty-first century?
-
Cohen P, (2002) Protein kinases-the major drug targets of the twenty-first century? Nat Rev Drug Discov 1, 309-315. (Pubitemid 37361447)
-
(2002)
Nature Reviews Drug Discovery
, vol.1
, Issue.4
, pp. 309-315
-
-
Cohen, P.1
-
2
-
-
57349138758
-
Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex
-
Liu XJ, Gingrich JR, Vargas-Caballero M, Dong YN, Sengar A, Beggs S, Wang SH, Ding HK, Frankland PW, &, Salter MW, (2008) Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex. Nat Med 14, 1325-1332.
-
(2008)
Nat Med
, vol.14
, pp. 1325-1332
-
-
Liu, X.J.1
Gingrich, J.R.2
Vargas-Caballero, M.3
Dong, Y.N.4
Sengar, A.5
Beggs, S.6
Wang, S.H.7
Ding, H.K.8
Frankland, P.W.9
Salter, M.W.10
-
3
-
-
0029896163
-
Regulation, substrates and functions of src
-
DOI 10.1016/0304-419X(96)00003-0
-
Brown MT, &, Cooper JA, (1996) Regulation, substrates and functions of src. Biochim Biophys Acta 1287, 121-149. (Pubitemid 26189191)
-
(1996)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1287
, Issue.2-3
, pp. 121-149
-
-
Brown, M.T.1
Cooper, J.A.2
-
4
-
-
0031025991
-
Three-dimensional structure of the tyrosine kinase c-Src
-
DOI 10.1038/385595a0
-
Xu W, Harrison SC, &, Eck MJ, (1997) Three-dimensional structure of the tyrosine kinase c-Src. Nature 385, 595-602. (Pubitemid 27087566)
-
(1997)
Nature
, vol.385
, Issue.6617
, pp. 595-602
-
-
Xu, W.1
Harrison, S.C.2
Eck, M.J.3
-
5
-
-
38349014380
-
Src family kinases: Regulation of their activities, levels and identification of new pathways
-
Ingley E, (2008) Src family kinases: regulation of their activities, levels and identification of new pathways. Biochim Biophys Acta 1784, 56-65.
-
(2008)
Biochim Biophys Acta
, vol.1784
, pp. 56-65
-
-
Ingley, E.1
-
6
-
-
17444374230
-
Src kinase regulation by phosphorylation and dephosphorylation
-
DOI 10.1016/j.bbrc.2005.03.012
-
Roskoski R Jr, (2005) Src kinase regulation by phosphorylation and dephosphorylation. Biochem Biophys Res Commun 331, 1-14. (Pubitemid 40545134)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.331
, Issue.1
, pp. 1-14
-
-
Roskoski Jr., R.1
-
7
-
-
0029887725
-
Subtype-specific regulation of recombinant NMDA receptor-channels by protein tyrosine kinases of the src family
-
Kohr G, &, Seeburg PH, (1996) Subtype-specific regulation of recombinant NMDA receptor-channels by protein tyrosine kinases of the src family. J Physiol 492, 445-452. (Pubitemid 26137754)
-
(1996)
Journal of Physiology
, vol.492
, Issue.2
, pp. 445-452
-
-
Kohr, G.1
Seeburg, P.H.2
-
8
-
-
0030680941
-
Fyn-kinase as a determinant of ethanol sensitivity: Relation to NMDA- Receptor function
-
DOI 10.1126/science.278.5338.698
-
Miyakawa T, Yagi T, Kitazawa H, Yasuda M, Kawai N, Tsuboi K, &, Niki H, (1997) Fyn-kinase as a determinant of ethanol sensitivity: relation to NMDA receptor function. Science 278, 698-701. (Pubitemid 27464970)
-
(1997)
Science
, vol.278
, Issue.5338
, pp. 698-701
-
-
Miyakawa, T.1
Yagi, T.2
Kitazawa, H.3
Yasuda, M.4
Kawai, N.5
Tsuboi, K.6
Niki, H.7
-
9
-
-
0031053363
-
NMDA channel regulation by channel-associated protein tyrosine kinase Src
-
DOI 10.1126/science.275.5300.674
-
Yu X-M, Askalan R, Keil GJI, &, Salter MW, (1997) NMDA channel regulation by channel-associated protein tyrosine kinase Src. Science 275, 674-678. (Pubitemid 27061336)
-
(1997)
Science
, vol.275
, Issue.5300
, pp. 674-678
-
-
Yu, X.-M.1
Askalan, R.2
Keil II, G.J.3
Salter, M.W.4
-
10
-
-
0033382249
-
Phosphorylation-dependent interaction of the N-methyl-D-aspartate receptor ε2 subunit with phosphatidylinositol 3-kinase
-
Hisatsune C, Umemori H, Mishina M, &, Yamamoto T, (1999) Phosphorylation-dependent interaction of the N-methyl-d-aspartate receptor Îμ2 subunit with phosphatidylinositol 3-kinase. Genes Cells 4, 657-666. (Pubitemid 30043546)
-
(1999)
Genes to Cells
, vol.4
, Issue.11
, pp. 657-666
-
-
Hisatsune, C.1
Umemori, H.2
Mishina, M.3
Yamamoto, T.4
-
11
-
-
0035369919
-
NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity
-
DOI 10.1016/S0959-4388(00)00216-6
-
Ali DW, &, Salter MW, (2001) NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity. Curr Opin Neurobiol 11, 336-342. (Pubitemid 32524099)
-
(2001)
Current Opinion in Neurobiology
, vol.11
, Issue.3
, pp. 336-342
-
-
Ali, D.W.1
Salter, M.W.2
-
12
-
-
1842731881
-
SRC kinases: A hub for NMDA receptor regulation
-
Salter MW, &, Kalia LV, (2004) Src kinases: a hub for NMDA receptor regulation. Nat Rev Neurosci 5, 317-328. (Pubitemid 38478658)
-
(2004)
Nature Reviews Neuroscience
, vol.5
, Issue.4
, pp. 317-328
-
-
Salter, M.W.1
Kalia, L.V.2
-
13
-
-
36649008903
-
Hippocampal long-term synaptic plasticity and signal amplification of NMDA receptors
-
MacDonald JF, Jackson MF, &, Beazely MA, (2006) Hippocampal long-term synaptic plasticity and signal amplification of NMDA receptors. Crit Rev Neurobiol 18, 71-84. (Pubitemid 350194079)
-
(2006)
Critical Reviews in Neurobiology
, vol.18
, Issue.1-2
, pp. 71-84
-
-
MacDonald, J.F.1
Jackson, M.F.2
Beazely, M.A.3
-
14
-
-
0034899681
-
Tyrosine phosphorylation of the N-methyl-D-aspartate receptor by exogenous and postsynaptic density-associated Src-family kinases
-
DOI 10.1046/j.1471-4159.2001.00433.x
-
Cheung HH, &, Gurd JW, (2001) Tyrosine phosphorylation of the N-methyl-d-aspartate receptor by exogenous and postsynaptic density-associated Src-family kinases. J Neurochem 78, 524-534. (Pubitemid 32729980)
-
(2001)
Journal of Neurochemistry
, vol.78
, Issue.3
, pp. 524-534
-
-
Cheung, H.H.1
Gurd, J.W.2
-
15
-
-
0035808467
-
Characterization of Fyn-mediated tyrosine phosphorylation sites on GluRε2 (NR2B) subunit of the N-methyl-D-aspartate receptor
-
DOI 10.1074/jbc.M008085200
-
Nakazawa T, Komai S, Tezuka T, Hisatsune C, Umemori H, Semba K, Mishina M, Manabe T, &, Yamamoto T, (2001) Characterization of Fyn-mediated tyrosine phosphorylation sites on GluRÎμ2 (NR2B) subunit of the N-methyl-d-aspartate receptor. J Biol Chem 276, 693-699. (Pubitemid 32050862)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.1
, pp. 693-699
-
-
Nakazawa, T.1
Komai, S.2
Tezuka, T.3
Hisatsune, C.4
Umemori, H.5
Semba, K.6
Mishina, M.7
Manabe, T.8
Yamamoto, T.9
-
16
-
-
0035050819
-
Identification of mouse NMDA receptor subunit NR2A C-terminal tyrosine sites phosphorylated by coexpression with v-Src
-
DOI 10.1046/j.1471-4159.2001.00255.x
-
Yang M, &, Leonard JP, (2001) Identification of mouse NMDA receptor subunit NR2A C-terminal tyrosine sites phosphorylated by coexpression with v-Src. J Neurochem 77, 580-588. (Pubitemid 32298752)
-
(2001)
Journal of Neurochemistry
, vol.77
, Issue.2
, pp. 580-588
-
-
Yang, M.1
Leonard, J.P.2
-
17
-
-
47749084247
-
Control of excitatory synaptic transmission by C-terminal Src kinase
-
Xu J, Weerapura M, Ali MK, Jackson MF, Li H, Lei G, Xue S, Kwan CL, Manolson MF, Yang K, et al. (2008) Control of excitatory synaptic transmission by C-terminal Src kinase. J Biol Chem 283, 17503-17514.
-
(2008)
J Biol Chem
, vol.283
, pp. 17503-17514
-
-
Xu, J.1
Weerapura, M.2
Ali, M.K.3
Jackson, M.F.4
Li, H.5
Lei, G.6
Xue, S.7
Kwan, C.L.8
Manolson, M.F.9
Yang, K.10
-
18
-
-
0031047981
-
Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs
-
DOI 10.1074/jbc.272.9.5501
-
Polte TR, &, Hanks SK, (1997) Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs. J Biol Chem 272, 5501-5509. (Pubitemid 27102371)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.9
, pp. 5501-5509
-
-
Polte, T.R.1
Hanks, S.K.2
-
19
-
-
0029157039
-
Structure-function analysis of SH3 domains: SH3 binding specificity altered by single amino acid substitutions
-
Weng Z, Rickles RJ, Feng S, Richard S, Shaw AS, Schreiber SL, &, Brugge JS, (1995) Structure-function analysis of SH3 domains: SH3 binding specificity altered by single amino acid substitutions. Mol Cell Biol 15, 5627-5634.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5627-5634
-
-
Weng, Z.1
Rickles, R.J.2
Feng, S.3
Richard, S.4
Shaw, A.S.5
Schreiber, S.L.6
Brugge, J.S.7
-
20
-
-
0028875162
-
Recognition and specificity in protein tyrosine kinase-mediated signalling
-
Songyang Z, &, Cantley LC, (1995) Recognition and specificity in protein tyrosine kinase-mediated signalling. Trends Biochem Sci 20, 470-475.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 470-475
-
-
Songyang, Z.1
Cantley, L.C.2
-
21
-
-
0030612112
-
pp60(v-src) transformation of rat cells but not chicken cells strongly correlates with low-affinity phosphopeptide binding by the SH2 domain
-
Verderame MF, (1997) pp60(v-src) transformation of rat cells but not chicken cells strongly correlates with low-affinity phosphopeptide binding by the SH2 domain. Mol Biol Cell 8, 843-854. (Pubitemid 27255026)
-
(1997)
Molecular Biology of the Cell
, vol.8
, Issue.5
, pp. 843-854
-
-
Verderame, M.F.1
-
22
-
-
77957753453
-
Characterization of neuronal Src kinase purified from a bacterial expression system
-
Marin V, Groveman BR, Qiao H, Xu J, Ali MK, Fang X-Q, Lin S-X, Rizkallah R, Hurt MH, Bienkiewicz EA, et al. (2010) Characterization of neuronal Src kinase purified from a bacterial expression system. Protein Expr Purif 74, 289-297.
-
(2010)
Protein Expr Purif
, vol.74
, pp. 289-297
-
-
Marin, V.1
Groveman, B.R.2
Qiao, H.3
Xu, J.4
Ali, M.K.5
Fang, X.-Q.6
Lin, S.-X.7
Rizkallah, R.8
Hurt, M.H.9
Bienkiewicz, E.A.10
-
23
-
-
0033582266
-
PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl- D-aspartate receptor subunit NR2A
-
DOI 10.1073/pnas.96.2.435
-
Tezuka T, Umemori H, Akiyama T, Nakanishi S, &, Yamamoto T, (1999) PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-d-aspartate receptor subunit NR2A. Proc Natl Acad Sci USA 96, 435-440. (Pubitemid 29061226)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.2
, pp. 435-440
-
-
Tezuka, T.1
Umemori, H.2
Akiyama, T.3
Nakanishi, S.4
Yamamoto, T.5
-
24
-
-
1942501611
-
Unique domain anchoring of Src to synaptic NMDA receptors via the mitochondrial protein NADH dehydrogenase subunit 2
-
DOI 10.1073/pnas.0401413101
-
Gingrich JR, Pelkey KA, Fam SR, Huang Y, Petralia RS, Wenthold RJ, &, Salter MW, (2004) Unique domain anchoring of Src to synaptic NMDA receptors via the mitochondrial protein NADH dehydrogenase subunit 2. Proc Natl Acad Sci USA 101, 6237-6242. (Pubitemid 38520558)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.16
, pp. 6237-6242
-
-
Gingrich, J.R.1
Pelkey, K.A.2
Fam, S.R.3
Huang, Y.4
Petralia, R.S.5
Wenthold, R.J.6
Salter, M.W.7
-
25
-
-
0033587177
-
Targeted disruption of the tyrosine phosphatase PTPα leads to constitutive downregulation of the kinases Src and Fyn
-
DOI 10.1016/S0960-9822(99)80238-3
-
Ponniah S, Wang DZ, Lim KL, &, Pallen CJ, (1999) Targeted disruption of the tyrosine phosphatase PTPα leads to constitutive downregulation of the kinases Src and Fyn. Curr Biol 9, 535-538. (Pubitemid 29257109)
-
(1999)
Current Biology
, vol.9
, Issue.10
, pp. 535-538
-
-
Ponniah, S.1
Wang, D.Z.M.2
Kah Leong, L.3
Pallen, C.J.4
-
26
-
-
0033587069
-
Receptor protein tyrosine phosphatase α activates Src-family kinases and controls integrin-mediated responses in fibroblasts
-
DOI 10.1016/S0960-9822(99)80234-6
-
Su J, Muranjan M, &, Sap J, (1999) Receptor protein tyrosine phosphatase α activates Src-family kinases and controls integrin-mediated responses in fibroblasts. Curr Biol 9, 505-511. (Pubitemid 29257105)
-
(1999)
Current Biology
, vol.9
, Issue.10
, pp. 505-511
-
-
Su, J.1
Muranjan, M.2
Sap, J.3
-
27
-
-
0025881470
-
c-src
-
Nada S, Okada M, MacAuley A, Cooper JA, &, Nakagawa H, (1991) Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src. Nature 351, 69-72. (Pubitemid 21896537)
-
(1991)
Nature
, vol.351
, Issue.6321
, pp. 69-72
-
-
Nada, S.1
Okada, M.2
MacAuley, A.3
Cooper, J.A.4
Nakagawa, H.5
-
28
-
-
0027289232
-
Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice
-
DOI 10.1016/0092-8674(93)90641-3
-
Imamoto A, &, Soriano P, (1993) Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice. Cell 73, 1117-1124. (Pubitemid 23180486)
-
(1993)
Cell
, vol.73
, Issue.6
, pp. 1117-1124
-
-
Imamoto, A.1
Soriano, P.2
-
29
-
-
18444401420
-
Gain control of N-methyl-D-aspartate receptor activity by receptor-like protein tyrosine phosphatase α
-
DOI 10.1093/emboj/cdf292
-
Lei G, Xue S, Chery N, Liu Q, Xu J, Kwan CL, Fu Y, Lu YM, Liu M, Harder KH, et al. (2002) Gain control of N-methyl-d-aspartate receptor activity by receptor-like protein tyrosine phopshatase α. EMBO J 21, 2977-2989. (Pubitemid 34670382)
-
(2002)
EMBO Journal
, vol.21
, Issue.12
, pp. 2977-2989
-
-
Lei, G.1
Xue, S.2
Chery, N.3
Liu, Q.4
Xu, J.5
Kwan, C.L.6
Fu, Y.-P.7
Lu, Y.-M.8
Liu, M.9
Harder, K.W.10
Yu, X.-M.11
-
30
-
-
0021173703
-
Identification of functional regions in the transforming protein of Fujinami sarcoma virus by in-phase insertion mutagenesis
-
Stone JC, Atkinson T, Smith M, &, Pawson T, (1984) Identification of functional regions in the transforming protein of Fujinami sarcoma virus by in-phase insertion mutagenesis. Cell 37, 549-558. (Pubitemid 14079049)
-
(1984)
Cell
, vol.37
, Issue.2
, pp. 549-558
-
-
Stone, J.C.1
Atkinson, T.2
Smith, M.3
Pawson, T.4
-
31
-
-
0022977712
-
A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130(gag-fps)
-
Sadowski I, Stone JC, &, Pawson T, (1986) A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps. Mol Cell Biol 6, 4396-4408. (Pubitemid 17217381)
-
(1986)
Molecular and Cellular Biology
, vol.6
, Issue.12
, pp. 4396-4408
-
-
Sadowski, I.1
Stone, J.C.2
Pawson, T.3
-
32
-
-
50249132542
-
Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation
-
Filippakopoulos P, Kofler M, Hantschel O, Gish GD, Grebien F, Salah E, Neudecker P, Kay LE, Turk BE, Superti-Furga G, et al. (2008) Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation. Cell 134, 793-803.
-
(2008)
Cell
, vol.134
, pp. 793-803
-
-
Filippakopoulos, P.1
Kofler, M.2
Hantschel, O.3
Gish, G.D.4
Grebien, F.5
Salah, E.6
Neudecker, P.7
Kay, L.E.8
Turk, B.E.9
Superti-Furga, G.10
-
33
-
-
33644871166
-
Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase
-
DOI 10.1016/j.molcel.2006.01.035, PII S1097276506000876
-
Nagar B, Hantschel O, Seeliger M, Davies JM, Weis WI, Superti-Furga G, &, Kuriyan J, (2006) Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase. Mol Cell 21, 787-798. (Pubitemid 43376129)
-
(2006)
Molecular Cell
, vol.21
, Issue.6
, pp. 787-798
-
-
Nagar, B.1
Hantschel, O.2
Seeliger, M.3
Davies, J.M.4
Weis, W.I.5
Superti-Furga, G.6
Kuriyan, J.7
-
34
-
-
34848838957
-
The Overnight Express autoinduction system: High-density cell growth and protein expression while you sleep
-
Grabski A, Mehler M, &, Drott D, (2005) The Overnight Express autoinduction system: high-density cell growth and protein expression while you sleep. Nat Methods 2, 233-235.
-
(2005)
Nat Methods
, vol.2
, pp. 233-235
-
-
Grabski, A.1
Mehler, M.2
Drott, D.3
|