Enhanced GDNF expression in dopaminergic cells of monkeys grafted with carotid body cell aggregates

Brain Research

Volumn 1375, Issue , 2011, Pages 120-127

  Luquin, M R ^a,b   Manrique, M ^b   Guillen J ^a   Arbizu, J ^b   Ordonez C ^a   Marcilla, I ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

1 methyl 4 phenyl 1,2,3,6 tetrahydropyridine; 18F DOPA; 18 F DOPA; bilaterally grafted; BL grafted; carotid body; carotid body cell aggregates; CB; CBCA; DA; DAergic; dopamine; dopaminergic; GDNF; glial cell line derived neurotrophic factor; MPTP; Parkinson's disease; PD; PET; positron emission tomography; SNpc; substantia nigra pars compacta; TH ir; tyrosine hydroxylase immunoreactive; UL grafted; unilaterally grafted

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 6 FLUORODOPA F 18; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOGRAFT; AUTOTRANSPLANTATION; BILATERAL STRIATUM CAROTID BODY CELL AGGREGATE AUTOTRANSPLANTATION; CAROTID BODY CELL AGGREGATE AUTOTRANSPLANTATION; CELL COUNT; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROLLED STUDY; CONVALESCENCE; DOPAMINERGIC ACTIVITY; DOPAMINERGIC NERVE CELL; EXPERIMENTAL MONKEY; FOLLOW UP; HISTOPATHOLOGY; IMMUNOREACTIVITY; IN VIVO STUDY; MALE; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSONISM; POSITRON EMISSION TOMOGRAPHY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHAM PROCEDURE; SUBSTANTIA NIGRA; UNILATERAL STRIATUM CAROTID BODY CELL AGGREGATE AUTOTRANSPLANTATION;

ANIMALS; CAROTID BODY; CELL COUNT; CELL TRANSPLANTATION; DIHYDROXYPHENYLALANINE; DOPAMINE; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GRAFT SURVIVAL; IMMUNOHISTOCHEMISTRY; MACACA FASCICULARIS; MALE; NEURONS; PHENOTYPE; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

ANIMALIA;

EID: 79651474103     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.12.033     Document Type: Article

References (35)

1. J. Arias-Stella, and J. Valcarcel Chief cell hyperplasia in the human carotid body at high altitudes; physiologic and pathologic significance Hum. Pathol. 7 1976 361 373
2. V. Arjona, A. Minguez-Castellanos, R.J. Montoro, A. Ortega, F. Escamilla, J.J. Toledo-Aral, R. Pardal, S. Mendez-Ferrer, J.M. Martin, M. Perez, M.J. Katati, E. Valencia, T. Garcia, and J. Lopez-Barneo Autotransplantation of human carotid body cell aggregates for treatment of Parkinson's disease Neurosurgery 53 2003 321 328 discussion 328-30
3. D. Bee, D.J. Pallot, and G.R. Barer Division of type I and endothelial cells in the hypoxic rat carotid body Acta. Anat. Basel 126 1986 226 229 (Pubitemid 16045710)
4. S. Belzunegui, A. Izal-Azcarate, W.S. Sebastian, P. Garrido-Gil, M. Vazquez-Claverie, B. Lopez, I. Marcilla, and M.R. Luquin Striatal carotid body graft promotes differentiation of neural progenitor cells into neurons in the olfactory bulb of adult hemiparkisonian rats Brain Res. 1217 2008 213 220
5. H.A. Boger, L.D. Middaugh, P. Huang, V. Zaman, A.C. Smith, B.J. Hoffer, A.C. Tomac, and A.C. Granholm A partial GDNF depletion leads to earlier age-related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra Exp. Neurol. 202 2006 336 347 (Pubitemid 44692677)
6. I.L. Cepeda, J. Flores, M.L. Cornfeldt, J.R. O'Kusky, and D.J. Doudet Human retinal pigment epithelial cell implants ameliorate motor deficits in two rat models of Parkinson disease J. Neuropathol. Exp. Neurol. 66 2007 576 584 (Pubitemid 47051703)
7. E.F. Espejo, R.J. Montoro, J.A. Armengol, and J. Lopez-Barneo Cellular and functional recovery of Parkinsonian rats after intrastriatal transplantation of carotid body cell aggregates Neuron 20 1998 197 206 (Pubitemid 28125065)
8. C.R. Freed, P.E. Greene, R.E. Breeze, W.Y. Tsai, W. DuMouchel, R. Kao, S. Dillon, H. Winfield, S. Culver, J.Q. Trojanowski, D. Eidelberg, and S. Fahn Transplantation of embryonic dopamine neurons for severe Parkinson's disease N. Engl. J. Med. 344 2001 710 719 (Pubitemid 32204988)
9. P. Garrido-Gil, S. Belzunegui, W. San Sebastian, A. Izal-Azcarate, B. Lopez, I. Marcilla, and M.R. Luquin 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine exposure fails to produce delayed degeneration of substantia nigra neurons in monkeys J. Neurosci. Res. 87 2009 586 597
10. D.M. Gash, Z. Zhang, Y. Ai, R. Grondin, R. Coffey, and G.A. Gerhardt Trophic factor distribution predicts functional recovery in parkinsonian monkeys Ann. Neurol. 58 2005 224 233 (Pubitemid 41098880)
11. R. Grondin, Z. Zhang, A. Yi, W.A. Cass, N. Maswood, A.H. Andersen, D.D. Elsberry, M.C. Klein, G.A. Gerhardt, and D.M. Gash Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys Brain 125 2002 2191 2201
12. H.J. Gundersen, and E.B. Jensen The efficiency of systematic sampling in stereology and its prediction J. Microsc. 147 Pt 3 1987 229 263
13. G. Hao, Y. Yao, J. Wang, L. Zhang, N. Viroonchatapan, and Z.Z. Wang Intrastriatal grafting of glomus cells ameliorates behavioral defects of Parkinsonian rats Physiol. Behav. 77 2002 519 525 (Pubitemid 36084395)
14. R. Hilker, A.T. Portman, J. Voges, M.J. Staal, L. Burghaus, T. van Laar, A. Koulousakis, R.P. Maguire, J. Pruim, B.M. de Jong, K. Herholz, V. Sturm, W.D. Heiss, and K.L. Leenders Disease progression continues in patients with advanced Parkinson's disease and effective subthalamic nucleus stimulation J. Neurol. Neurosurg. Psychiatry 76 2005 1217 1221 (Pubitemid 41208371)
15. A. Izal-Azcarate, S. Belzunegui, W. San Sebastian, P. Garrido-Gil, M. Vazquez-Claverie, B. Lopez, I. Marcilla, and M.A. Luquin Immunohistochemical characterization of the rat carotid body Respir. Physiol. Neurobiol. 161 2008 95 99 (Pubitemid 351324213)
16. C. Jollivet, C.N. Montero-Menei, M.C. Venier-Julienne, A. Sapin, J.P. Benoit, and P. Menei Striatal tyrosine hydroxylase immunoreactive neurons are induced by L-dihydroxyphenylalanine and nerve growth factor treatment in 6-hydroxydopamine lesioned rats Neurosci. Lett. 362 2004 79 82 (Pubitemid 38759072)
17. J.H. Kim, J.M. Auerbach, J.A. Rodriguez-Gomez, I. Velasco, D. Gavin, N. Lumelsky, S.H. Lee, J. Nguyen, R. Sanchez-Pernaute, K. Bankiewicz, and R. McKay Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease Nature 418 2002 50 56 (Pubitemid 34742566)
18. H. Kishima, T. Poyot, J. Bloch, J. Dauguet, F. Conde, F. Dolle, F. Hinnen, W. Pralong, S. Palfi, N. Deglon, P. Aebischer, and P. Hantraye Encapsulated GDNF-producing C2C12 cells for Parkinson's disease: a pre-clinical study in chronic MPTP-treated baboons Neurobiol. Dis. 16 2004 428 439 (Pubitemid 38757323)
19. J.H. Kordower, M.E. Emborg, J. Bloch, S.Y. Ma, Y. Chu, L. Leventhal, J. McBride, E.Y. Chen, S. Palfi, B.Z. Roitberg, W.D. Brown, J.E. Holden, R. Pyzalski, M.D. Taylor, P. Carvey, Z. Ling, D. Trono, P. Hantraye, N. Deglon, and P. Aebischer Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease Science 290 2000 767 773
20. M.R. Luquin, R.J. Montoro, J. Guillen, L. Saldise, R. Insausti, J. Del Rio, and J. Lopez-Barneo Recovery of chronic parkinsonian monkeys by autotransplants of carotid body cell aggregates into putamen Neuron 22 1999 743 750 (Pubitemid 29203497)
21. A. Minguez-Castellanos, F. Escamilla-Sevilla, G.R. Hotton, J.J. Toledo-Aral, A. Ortega-Moreno, S. Mendez-Ferrer, J.M. Martin-Linares, M.J. Katati, P. Mir, J. Villadiego, M. Meersmans, M. Perez-Garcia, D.J. Brooks, V. Arjona, and J. Lopez-Barneo Carotid body autotransplantation in Parkinson disease: a clinical and positron emission tomography study J. Neurol. Neurosurg. Psychiatry 78 2007 825 831 (Pubitemid 47204586)
22. C.W. Olanow, C.G. Goetz, J.H. Kordower, A.J. Stoessl, V. Sossi, M.F. Brin, K.M. Shannon, G.M. Nauert, D.P. Perl, J. Godbold, and T.B. Freeman A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease Ann. Neurol. 54 2003 403 414 (Pubitemid 37072046)
23. M. Paciga, and C.A. Nurse Basic FGF localization in rat carotid body: paracrine role in O2 -chemoreceptor survival NeuroReport 12 2001 3287 3291 (Pubitemid 33010658)
24. S. Palfi, L. Leventhal, Y. Chu, S.Y. Ma, M. Emborg, R. Bakay, N. Deglon, P. Hantraye, P. Aebischer, and J.H. Kordower Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration J. Neurosci. 22 2002 4942 4954 (Pubitemid 37465609)
25. R. Pardal, P. Ortega-Saenz, R. Duran, and J. Lopez-Barneo Glia-like stem cells sustain physiologic neurogenesis in the adult mammalian carotid body Cell 131 2007 364 377 (Pubitemid 47576136)
26. A. Pascual, M. Hidalgo-Figueroa, J.I. Piruat, C.O. Pintado, R. Gomez-Diaz, and J. Lopez-Barneo Absolute requirement of GDNF for adult catecholaminergic neuron survival Nat. Neurosci. 11 2008 755 761 (Pubitemid 351896676)
27. M. Peschanski, G. Defer, J.P. N'Guyen, F. Ricolfi, J.C. Monfort, P. Remy, C. Geny, Y. Samson, P. Hantraye, and R. Jeny Bilateral motor improvement and alteration of L-dopa effect in two patients with Parkinson's disease following intrastriatal transplantation of foetal ventral mesencephalon Brain 117 Pt 3 1994 487 499 (Pubitemid 24225897)
28. W. San Sebastian, J. Guillen, M. Manrique, S. Belzunegui, E. Ciordia, A. Izal-Azcarate, P. Garrido-Gil, M. Vazquez-Claverie, and M.R. Luquin Modification of the number and phenotype of striatal dopaminergic cells by carotid body graft Brain 130 2007 1306 1316 (Pubitemid 47355955)
29. J.T. Slevin, D.M. Gash, C.D. Smith, G.A. Gerhardt, R. Kryscio, H. Chebrolu, A. Walton, R. Wagner, and A.B. Young Unilateral intraputaminal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year each of treatment and withdrawal Neurosurg. Focus 20 2006 E1
30. Y. Takagi, J. Takahashi, H. Saiki, A. Morizane, T. Hayashi, Y. Kishi, H. Fukuda, Y. Okamoto, M. Koyanagi, M. Ideguchi, H. Hayashi, T. Imazato, H. Kawasaki, H. Suemori, S. Omachi, H. Iida, N. Itoh, N. Nakatsuji, Y. Sasai, and N. Hashimoto Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model J. Clin. Invest. 115 2005 102 109 (Pubitemid 40385510)
31. A. Tomac, E. Lindqvist, L.F. Lin, S.O. Ogren, D. Young, B.J. Hoffer, and L. Olson Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo Nature 373 1995 335 339
32. J. Villadiego, S. Mendez-Ferrer, T. Valdes-Sanchez, I. Silos-Santiago, I. Farinas, J. Lopez-Barneo, and J.J. Toledo-Aral Selective glial cell line-derived neurotrophic factor production in adult dopaminergic carotid body cells in situ and after intrastriatal transplantation J. Neurosci. 25 2005 4091 4098 (Pubitemid 40563384)
33. Z.Y. Wang, and G.E. Bisgard Postnatal growth of the carotid body Respir. Physiol. Neurobiol. 149 2005 181 190 (Pubitemid 41406220)
34. R.L. Watts, C.D. Raiser, N.P. Stover, M.L. Cornfeldt, A.W. Schweikert, R.C. Allen, T. Subramanian, D. Doudet, C.R. Honey, and R.A. Bakay Stereotaxic intrastriatal implantation of human retinal pigment epithelial (hRPE) cells attached to gelatin microcarriers: a potential new cell therapy for Parkinson's disease J. Neural Transm. Suppl. 2003 215 227 (Pubitemid 38339958)
35. M.J. West Stereological methods for stimating the total number of neurons and synapes: issues of precision and bias Trends Neurosci. 22 1999 51 61 (Pubitemid 29125550)