Deficiency of CD3gamma, delta, epsilon, and zeta expression in T cells from AML patients

Hematology

Volumn 16, Issue 1, 2011, Pages 31-36

  Chen, Shaohua ^a   Zha, Xianfeng ^a   Yang, Lijian ^a   Li, Bo ^a   Liye, Zhong ^a   Li, Yangqiu ^a,b  

^a MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

^b JINAN UNIVERSITY   (China)

Author keywords

AML; CD3gamma; Delta; Epsilon and zeta chain; Gene expression; T cells

Indexed keywords

CD3 ANTIGEN; CD3 DELTA CHAIN; CD3 EPSILON CHAIN; CD3 GAMMA CHAIN; CD3 ZETA CHAIN; MEMBRANE PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; ARTICLE; CELL SELECTION; CELLULAR IMMUNODEFICIENCY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ADOLESCENT; ADULT; AGED; ANTIGENS, CD3; CASE-CONTROL STUDIES; FEMALE; GENE EXPRESSION PROFILING; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL; RNA, MESSENGER; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; YOUNG ADULT;

EID: 79551708210     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453311X12902908411832     Document Type: Article

References (28)

1. Deschler B, Lübbert M. Acute myeloid leukemia: epidemiology and etiology. Cancer 2006;107:2099-107.
2. Erba HP. Prognostic factor in elderly patients with AML and the implications for treatment. Hematology Am Soc Hematol Educ Program 2007;2007:420-8.
3. Li Y, Yin Q, Yang L, Chen S, Geng S, Wu X, et al. Reduced levels of recent thymic emigrants in acute myeloid leukemia patients. Cancer Immunol Immunother 2009;58:1047-55.
4. Li Y, Chen S, Yang L, Zhou Y, Wu X, Huang M, et al. Clonal expanded TCR Vβ T cells in patients with APL. Hematology 2005;10:135-9.
5. Rezvany M., Jeddi-Tehrani M, Osterborg A,Kimby E, WigzellH, Mellstedt H. Oligoclonal TCR BV gene usage in B-cell chronic lymphocytic leukemia: major perturbations are preferentially seen within the CD4 T-cell subset. Blood 1999; 94:1063-9.
6. Chen X, Woiciechowsky A, Raffegerst S, Schendel D, Kolb HJ, Roskrow M. Impaired expression of the CD3-zeta chain in peripheral blood T cells of patients with chronic myeloid leukaemia results in an increased susceptibility to apoptosis. Br J Haematol 2000;111:817-25.
7. Chen S, Yang L, Chen S, Li Y. TCR ζ chain expression in T cells from patients with CML. Hematology 2009;14:95-100.
8. Wang L, Zhu K, Zha X, Chen S, Yang L, Chen S, et al. Evolution of T-cell clonality in a patient with Ph-negative acute lymphocytic leukemia occurring after interferon and imatinib therapy for Ph-positive chronic myeloid leukemia. J Hematol Oncol 2010;3:14.
9. Call ME, Wucherpfenning KW. The T cell receptor: critical role of the membrane environment in receptor assembly and function. Annu Rev Immunol 2005;23:101-25.
10. Clevers H, Alarcon B, Wileman T, Terhorst C. The T cell receptor/CD3 complex: a dynamic protein ensemble. Annu Rev Immunol 1988;6:629-62.
11. Call ME, Pyrdol J, Wucherpfenning KW. Stoichiometry of the T-cell receptor-CD3 complex and key intermediates assembled in the endoplasmic reticulum. EMBO J 2004;23:2348-57.
12. Arnett KL, Harrison SC, Wiley DC. Crystal structure of a human CD3-epsilon/delta dimmer in complex with a UCHT1 single-chain antibody fragment. Proc Natl Acad Sci USA 2004;101:16268-73.
13. Abraham RT, Weiss A. Jurkat T cells and development of the T-cell receptor signaling paradigm. Nat Rev Immunol 2004;4:301-8.
14. Fischer A, de Saint Basile G, Le Deist F. CD3 deficiens. Curr Opin Allergy Clin Immunol 2005;5:491-5.
15. Liossis SN, Ding XZ, Dennis GJ, Tsokos GC. Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain. J Clin Invest 1998;101:1448-57.
16. Solomou EE, Wong S, Visconte V, Gibellini F, Young NS. Decreased TCR zeta-chain expression in T cells from patients with acquired aplastic anaemia. Br J Haematol 2007;138:72-6.
17. Torelli GF, Paolini R, Tatarelli C, Soriani A, Vitale A, Guarini A, et al. Defective expression of the T-cell receptor-CD3 zeta chain in T-cell acute lymphoblastic leukaemia. Br J Haematol 2003;120:201-8.
18. Mozaffari F, Hansson L, Kiaii S, Ju X, Rossmann ED, Rabbani H, et al. Signalling molecules and cytokine production in T cells of multiple myeloma-increased abnormalities with advancing stage. Br J Haematol 2004;124:315-24.
19. + T-cells from human umbilical cord blood. Hematology 2010;15:230-5.
20. + pediatric ALL. Blood 2003;101:2743-7.
21. Li Y, Chen S, Yang L, Li B, Chan JY, Cai D. TRGV and TRDV repertoire distribution and clonality of T cells from umbilical cord Blood. Transpl Immunol 2009;20:155-62.
22. Hadden JW. Immunodeficiency and cancer: prospects for correction. Int Immunopharmacol 2003;3:1061-71.
23. Costello RT, Rey J, Fauriat C, Gastaut JA, Olive D. New approaches in the immunotherapy of haematological malignancies. Eur J Haematol 2003;70:333-45.
24. DeJarnette JB, Sommers CL, Huang K, Woodside KJ, Emmons R, Katz K, et al. Specific requirement for CD3epsilon in T cell development. Proc Natl Acad Sci USA 1998;95:14909-14.
25. Kiaii S, Choudhury A, Mozaffari F, Kimby E, Osterborg A, Mellstedt H. Signaling molecules and cytokine production in T cells of patients with B-cell chronic lymphocytic leukemia (B-CLL): comparison of indolent and progressive disease. Med Oncol 2005;22:291-302.
26. Shores EW, Love PE. TCRζ chain in T cell development and selection. Curr Opin Immunol 1997;9:380-9.
27. Dadi HK, Simon AJ, Roifman CM. Effect of CD3δ deficiency on maturation of α/β and γ/δ T-cell lineages in severe combined immunodeficiency. N Engl J Med 2003;349:1821-8.
28. Roifman CM. CD3δ immunodeficiency. Curr Opin Allergy Clin Immunol 2004;4:479-84.